PubRank

Frederick Sachs

Author PubWeight™ 83.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Polycystin-1 and -2 dosage regulates pressure sensing. Cell 2009 3.36
2 Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers. Nature 2004 3.12
3 Maximum likelihood estimation of ion channel kinetics from macroscopic currents. Biophys J 2005 2.18
4 Effects of stretch-activated channel blockers on [Ca2+]i and muscle damage in the mdx mouse. J Physiol 2004 2.17
5 Biophysics and structure of the patch and the gigaseal. Biophys J 2009 2.15
6 The mechanosensitive ion channel Piezo1 is inhibited by the peptide GsMTx4. Biochemistry 2011 1.93
7 Xerocytosis is caused by mutations that alter the kinetics of the mechanosensitive channel PIEZO1. Proc Natl Acad Sci U S A 2013 1.86
8 Revisiting TRPC1 and TRPC6 mechanosensitivity. Pflugers Arch 2007 1.81
9 Desensitization of mechano-gated K2P channels. Proc Natl Acad Sci U S A 2006 1.65
10 Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel. J Physiol 2010 1.58
11 High-speed pressure clamp. Pflugers Arch 2002 1.56
12 Mechanosensitive channel properties and membrane mechanics in mouse dystrophic myotubes. J Physiol 2007 1.55
13 Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology. Toxicon 2006 1.49
14 A fluorescence energy transfer-based mechanical stress sensor for specific proteins in situ. FEBS J 2008 1.49
15 Connexins are mechanosensitive. Am J Physiol Cell Physiol 2004 1.46
16 A simple automated stimulator of mechanically induced arrhythmias in the isolated rat heart. Exp Physiol 2009 1.44
17 Gating the mechanical channel Piezo1: a comparison between whole-cell and patch recording. Channels (Austin) 2012 1.43
18 Atomic force microscopy analysis of cell volume regulation. Phys Rev E Stat Nonlin Soft Matter Phys 2008 1.37
19 Maximum likelihood estimation of molecular motor kinetics from staircase dwell-time sequences. Biophys J 2006 1.35
20 Dynamic regulation of mechanosensitive channels: capacitance used to monitor patch tension in real time. Phys Biol 2004 1.35
21 Solution structure of peptide toxins that block mechanosensitive ion channels. J Biol Chem 2002 1.34
22 Visualizing dynamic cytoplasmic forces with a compliance-matched FRET sensor. J Cell Sci 2010 1.30
23 Molecular force transduction by ion channels: diversity and unifying principles. J Cell Sci 2012 1.28
24 Ca2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular stores. J Neurosci 2006 1.25
25 Streptomycin reduces stretch-induced membrane permeability in muscles from mdx mice. Neuromuscul Disord 2006 1.25
26 cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels. Toxicon 2003 1.25
27 Piezo1: properties of a cation selective mechanical channel. Channels (Austin) 2012 1.16
28 Extracting dwell time sequences from processive molecular motor data. Biophys J 2006 1.16
29 Is lipid bilayer binding a common property of inhibitor cysteine knot ion-channel blockers? Biophys J 2007 1.10
30 Mechanosensation and endothelin in astrocytes--hypothetical roles in CNS pathophysiology. Brain Res Brain Res Rev 2004 1.09
31 Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes. PLoS One 2010 1.09
32 Microfluidic actuation using electrochemically generated bubbles. Anal Chem 2002 1.08
33 Orientation-based FRET sensor for real-time imaging of cellular forces. J Cell Sci 2012 1.08
34 Human PIEZO1: removing inactivation. Biophys J 2013 1.07
35 A mechanosensitive ion channel regulating cell volume. Am J Physiol Cell Physiol 2010 1.06
36 Effects of GsMTx4 on bacterial mechanosensitive channels in inside-out patches from giant spheroplasts. Biophys J 2010 1.06
37 Evidence for non-independent gating of P2X2 receptors expressed in Xenopus oocytes. BMC Neurosci 2002 1.04
38 Dynamic properties of stretch-activated K+ channels in adult rat atrial myocytes. Prog Biophys Mol Biol 2003 1.04
39 Mechanosensitive ion channels as drug targets. Curr Drug Targets CNS Neurol Disord 2004 1.01
40 Electromechanical coupling in the membranes of Shaker-transfected HEK cells. Proc Natl Acad Sci U S A 2009 1.01
41 Volume cytometry: microfluidic sensor for high-throughput screening in real time. Anal Chem 2005 0.99
42 Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids. Pflugers Arch 2007 0.99
43 Real Time FRET Based Detection of Mechanical Stress in Cytoskeletal and Extracellular Matrix Proteins. Cell Mol Bioeng 2011 0.97
44 The slow force response to stretch in atrial and ventricular myocardium from human heart: functional relevance and subcellular mechanisms. Prog Biophys Mol Biol 2008 0.97
45 Genetically encoded force sensors for measuring mechanical forces in proteins. Commun Integr Biol 2011 0.96
46 Drift-free atomic force microscopy measurements of cell height and mechanical properties. Rev Sci Instrum 2007 0.91
47 Microfluidic chip to produce temperature jumps for electrophysiology. Anal Chem 2008 0.90
48 Stretch-activated potassium channels in hypotonically induced blebs of atrial myocytes. J Membr Biol 2008 0.90
49 Dynamic effects of Hg2+-induced changes in cell volume. Cell Biochem Biophys 2008 0.90
50 Modeling ion channels in the gigaseal. Biophys J 2011 0.89
51 Stretch induced endothelin-1 secretion by adult rat astrocytes involves calcium influx via stretch-activated ion channels (SACs). Biochem Biophys Res Commun 2011 0.89
52 Caveolae regulation of mechanosensitive channel function in myotubes. PLoS One 2013 0.87
53 Shear-induced volume decrease in MDCK cells. Cell Physiol Biochem 2012 0.87
54 Angiotensin II and myosin light-chain phosphorylation contribute to the stretch-induced slow force response in human atrial myocardium. Cardiovasc Res 2008 0.86
55 Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Rep 2012 0.86
56 Fluorescence-based force/tension sensors: a novel tool to visualize mechanical forces in structural proteins in live cells. Antioxid Redox Signal 2014 0.85
57 Interplay between cytoskeletal stresses and cell adaptation under chronic flow. PLoS One 2012 0.84
58 High throughput assay of diffusion through Cx43 gap junction channels with a microfluidic chip. Anal Chem 2010 0.84
59 Microfabricated torsion levers optimized for low force and high-frequency operation in fluids. Ultramicroscopy 2006 0.83
60 Hereditary xerocytosis revisited. Am J Hematol 2014 0.82
61 Small quantum dots conjugated to nanobodies as immunofluorescence probes for nanometric microscopy. Bioconjug Chem 2014 0.81
62 Gigaseal mechanics: creep of the gigaseal under the action of pressure, adhesion, and voltage. J Phys Chem B 2014 0.81
63 Probing the double layer: effect of image forces on AFM. Biophys J 2006 0.80
64 Neurite outgrowth from PC12 cells is enhanced by an inhibitor of mechanical channels. Neurosci Lett 2010 0.79
65 Cell biology: The sensation of stretch. Nature 2012 0.79
66 Flexoelectricity and elasticity of asymmetric biomembranes. Phys Rev E Stat Nonlin Soft Matter Phys 2002 0.79
67 Mechanical effects on KATP channel gating in rat ventricular myocytes. PLoS One 2013 0.77
68 Retaining your identity under stress. Nat Struct Biol 2002 0.77
69 Cholesterol depletion facilitates recovery from hypotonic cell swelling in CHO cells. Cell Physiol Biochem 2011 0.77
70 A microfluidic platform for measuring electrical activity across cells. Biomicrofluidics 2012 0.75