PubRank

Dirk Schübeler

Author PubWeight™ 144.69‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007 20.22
2 Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 2005 15.37
3 DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 2011 8.75
4 Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 2008 7.68
5 Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol 2008 4.50
6 Targets and dynamics of promoter DNA methylation during early mouse development. Nat Genet 2010 4.27
7 Identification of genetic elements that autonomously determine DNA methylation states. Nat Genet 2011 4.04
8 Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs. Cell 2010 3.57
9 Genomic patterns of DNA methylation: targets and function of an epigenetic mark. Curr Opin Cell Biol 2007 3.54
10 BLUEPRINT to decode the epigenetic signature written in blood. Nat Biotechnol 2012 3.24
11 Determinants and dynamics of genome accessibility. Nat Rev Genet 2011 3.15
12 A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus. Mol Cell Biol 2003 3.09
13 Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa. Nat Struct Mol Biol 2010 3.07
14 PcG proteins, DNA methylation, and gene repression by chromatin looping. PLoS Biol 2008 2.85
15 DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity. EMBO J 2008 2.81
16 DNA replication-timing analysis of human chromosome 22 at high resolution and different developmental states. Proc Natl Acad Sci U S A 2004 2.66
17 Genetics and epigenetics: stability and plasticity during cellular differentiation. Trends Genet 2009 2.57
18 Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias. Genes Dev 2005 2.26
19 Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila. EMBO J 2007 2.19
20 Methylated DNA immunoprecipitation (MeDIP). Methods Mol Biol 2009 2.17
21 Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome. Genes Dev 2009 2.08
22 Tackling the epigenome: challenges and opportunities for collaboration. Nat Biotechnol 2010 2.04
23 A question of timing: emerging links between transcription and replication. Curr Opin Genet Dev 2006 2.00
24 New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood 2008 1.97
25 Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells. PLoS Genet 2011 1.97
26 Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming. Cancer Cell 2013 1.85
27 Methylation-dependent and -independent genomic targeting principles of the MBD protein family. Cell 2013 1.79
28 Relics of repeat-induced point mutation direct heterochromatin formation in Neurospora crassa. Genome Res 2008 1.61
29 Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing. Nat Struct Mol Biol 2010 1.57
30 DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation. Mol Cell Biol 2002 1.57
31 Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa. Nat Struct Mol Biol 2013 1.54
32 Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting. Genome Res 2012 1.54
33 ChIPs of the beta-globin locus: unraveling gene regulation within an active domain. Curr Opin Genet Dev 2002 1.45
34 Epigenomics: mapping the methylome. Cell Cycle 2006 1.42
35 Methylation of histones: playing memory with DNA. Curr Opin Cell Biol 2005 1.40
36 A chromatin-modifying function of JNK during stem cell differentiation. Nat Genet 2011 1.31
37 DNA methylation is required for the control of stem cell differentiation in the small intestine. Genes Dev 2014 1.31
38 Transcription-coupled methylation of histone H3 at lysine 36 regulates dosage compensation by enhancing recruitment of the MSL complex in Drosophila melanogaster. Mol Cell Biol 2008 1.28
39 Identification of active regulatory regions from DNA methylation data. Nucleic Acids Res 2013 1.26
40 Heterochromatin protein 1 (HP1) modulates replication timing of the Drosophila genome. Genome Res 2010 1.12
41 Chromatin measurements reveal contributions of synthesis and decay to steady-state mRNA levels. Mol Syst Biol 2012 1.10
42 Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome. Genome Biol 2012 1.09
43 H3K64 trimethylation marks heterochromatin and is dynamically remodeled during developmental reprogramming. Nat Struct Mol Biol 2009 1.08
44 Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state. Proc Natl Acad Sci U S A 2012 1.02
45 Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice. PLoS One 2011 1.00
46 Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation. PLoS One 2013 0.99
47 Ezh2 is required for neural crest-derived cartilage and bone formation. Development 2014 0.97
48 RNA polymerase II: just stopping by. Cell 2007 0.96
49 Epigenomics: Methylation matters. Nature 2009 0.94
50 Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion. Toxicol Sci 2012 0.92
51 Gene regulation and priming by topoisomerase IIα in embryonic stem cells. Nat Commun 2013 0.87
52 Chromatin: sub out the replacement. Curr Biol 2009 0.80
53 Tracking the evolution of cancer methylomes. Nat Genet 2012 0.78
54 Enhancing genome annotation with chromatin. Nat Genet 2007 0.77
55 Twisting chromatin in stem cells. EMBO J 2013 0.76