Nuclear trafficking of the epidermal growth factor receptor family membrane proteins.

EGF receptor trafficking: consequences for signaling and cancer. Trends Cell Biol (2013) 1.77

Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations. Cancer Lett (2012) 1.73

EGFR nuclear translocation modulates DNA repair following cisplatin and ionizing radiation treatment. Cancer Res (2011) 1.66

Endocytosis and signaling: cell logistics shape the eukaryotic cell plan. Physiol Rev (2012) 1.61

Spatial regulation of receptor tyrosine kinases in development and cancer. Nat Rev Cancer (2012) 1.44

The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus. J Biol Chem (2010) 1.36

Nuclear EGFR as a molecular target in cancer. Radiother Oncol (2013) 1.33

Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family. Cell Biosci (2012) 1.31

COPI-mediated retrograde trafficking from the Golgi to the ER regulates EGFR nuclear transport. Biochem Biophys Res Commun (2010) 1.16

The secret life of kinases: functions beyond catalysis. Cell Commun Signal (2011) 1.13

Cleavage and nuclear localization of the rice XA21 immune receptor. Nat Commun (2012) 1.10

Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor. Oncogene (2012) 1.06

FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior. J Cell Biol (2012) 1.04

Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes. Cancer Res (2011) 1.01

Membrane-bound trafficking regulates nuclear transport of integral epidermal growth factor receptor (EGFR) and ErbB-2. J Biol Chem (2012) 1.00

MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function. Genes Dev (2012) 0.94

Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells. Annu Rev Physiol (2013) 0.94

Prolonged exposure to a Mer ligand in leukemia: Gas6 favors expression of a partial Mer glycoform and reveals a novel role for Mer in the nucleus. PLoS One (2012) 0.93

Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway. Biochem Biophys Res Commun (2011) 0.93

Receptor tyrosine kinases in the nucleus. Cold Spring Harb Perspect Biol (2013) 0.93

EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4. Dev Cell (2014) 0.92

IQGAP3 promotes EGFR-ERK signaling and the growth and metastasis of lung cancer cells. PLoS One (2014) 0.91

iNOS: a potential therapeutic target for malignant glioma. Curr Mol Med (2013) 0.89

Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription. PLoS One (2013) 0.88

Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter. Int J Cancer (2012) 0.88

Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking. Oncogene (2013) 0.87

Steroid-like signalling by interferons: making sense of specific gene activation by cytokines. Biochem J (2012) 0.87

Odin (ANKS1A) modulates EGF receptor recycling and stability. PLoS One (2013) 0.86

Chromatin-tethered MAPKs. Curr Opin Cell Biol (2013) 0.86

Characterization of monocarboxylate transporters (MCTs) expression in soft tissue sarcomas: distinct prognostic impact of MCT1 sub-cellular localization. J Transl Med (2014) 0.85

Epstein-Barr Virus encoded LMP1 regulates cyclin D1 promoter activity by nuclear EGFR and STAT3 in CNE1 cells. J Exp Clin Cancer Res (2013) 0.85

Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response. Cell Res (2015) 0.82

Blocking c-Met-mediated PARP1 phosphorylation enhances anti-tumor effects of PARP inhibitors. Nat Med (2016) 0.82

Kinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitors. Stem Cells Transl Med (2014) 0.82

Phosphoproteomic studies of receptor tyrosine kinases: future perspectives. Mol Biosyst (2011) 0.82

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling. Carcinogenesis (2015) 0.81

Activation of Keap1/Nrf2 signaling pathway by nuclear epidermal growth factor receptor in cancer cells. Am J Transl Res (2014) 0.81

Unusual localization and translocation of TRPV4 protein in cultured ventricular myocytes of the neonatal rat. Eur J Histochem (2012) 0.80

Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells. Oncogene (2013) 0.80

MIR144 and MIR451 regulate human erythropoiesis via RAB14. Br J Haematol (2014) 0.80

Involvement of de novo synthesized palmitate and mitochondrial EGFR in EGF induced mitochondrial fusion of cancer cells. Cell Cycle (2014) 0.80

Nuclear trafficking of EGFR by Vps34 represses Arf expression to promote lung tumor cell survival. Oncogene (2015) 0.79

Non-canonical signaling mode of the epidermal growth factor receptor family. Am J Cancer Res (2015) 0.79

Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cells. PLoS One (2012) 0.79

Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant human glioma cells. Cancer Biol Ther (2015) 0.78

Inner nuclear membrane localization of epidermal growth factor receptor (EGFR) in spontaneous canine model of invasive micropapillary carcinoma of the mammary gland. Pathol Res Pract (2015) 0.78

PML represses lung cancer metastasis by suppressing the nuclear EGFR-mediated transcriptional activation of MMP2. Cell Cycle (2014) 0.77

EGFs and ERBBs--brief history and prospects. Semin Cell Dev Biol (2010) 0.77

On mammary gland growth factors: roles in normal development and in cancer. Cold Spring Harb Perspect Biol (2012) 0.77

Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker Assessment. Front Oncol (2015) 0.76

Protein mislocalization: mechanisms, functions and clinical applications in cancer. Biochim Biophys Acta (2014) 0.76

Antagonizing c-Cbl enhances EGFR-dependent corneal epithelial homeostasis. Invest Ophthalmol Vis Sci (2014) 0.76

Study on chemotherapeutic sensitizing effect of nimotuzumab on different human esophageal squamous carcinoma cells. Oncol Lett (2015) 0.75

HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas. Oncotarget (2016) 0.75

The tomato cell death suppressor Adi3 is restricted to the endosomal system in response to the Pseudomonas syringae effector protein AvrPto. PLoS One (2014) 0.75

Subcellular localization of EGFR in esophageal carcinoma cell lines. J Cell Commun Signal (2015) 0.75

Endosomal escape efficiency of fusogenic B18 and B55 peptides fused with anti-EGFR single chain Fv as estimated by nuclear translocation. J Biochem (2015) 0.75

Effects of different ligands on epidermal growth factor receptor (EGFR) nuclear translocation. Biochem Biophys Res Commun (2016) 0.75

Analysis of origin and protein-protein interaction maps suggests distinct oncogenic role of nuclear EGFR during cancer evolution. J Cancer (2017) 0.75

Untangling the ErbB signalling network. Nat Rev Mol Cell Biol (2001) 28.05

ERBB receptors and cancer: the complexity of targeted inhibitors. Nat Rev Cancer (2005) 16.73

Regulated portals of entry into the cell. Nature (2003) 15.33

Endocytic recycling. Nat Rev Mol Cell Biol (2004) 10.87

EGF-ERBB signalling: towards the systems level. Nat Rev Mol Cell Biol (2006) 10.39

Mechanisms of endocytosis. Annu Rev Biochem (2009) 10.07

EGFR antagonists in cancer treatment. N Engl J Med (2008) 9.68

Rab conversion as a mechanism of progression from early to late endosomes. Cell (2005) 8.96

Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol (2001) 7.22

Pathways of clathrin-independent endocytosis. Nat Rev Mol Cell Biol (2007) 6.48

The biogenesis of multivesicular endosomes. Nat Rev Mol Cell Biol (2004) 6.31

The emerging shape of the ESCRT machinery. Nat Rev Mol Cell Biol (2007) 6.05

The EGFR family and its ligands in human cancer. signalling mechanisms and therapeutic opportunities. Eur J Cancer (2001) 5.96

Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol (2009) 5.83

Pathways and mechanisms of endocytic recycling. Nat Rev Mol Cell Biol (2009) 5.60

Clathrin-independent endocytosis of ubiquitinated cargos. Proc Natl Acad Sci U S A (2005) 5.37

Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell (2003) 5.05

Molecular mechanism of the nuclear protein import cycle. Nat Rev Mol Cell Biol (2007) 5.02

gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science (2001) 4.90

ErbB receptors and signaling pathways in cancer. Curr Opin Cell Biol (2009) 4.40

Derailed endocytosis: an emerging feature of cancer. Nat Rev Cancer (2008) 4.25

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol (2009) 4.16

Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J Natl Cancer Inst (2007) 4.03

APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors. Oncogene (2009) 3.86

Crossing the nuclear envelope: hierarchical regulation of nucleocytoplasmic transport. Science (2007) 3.86

Endocytosis and intracellular trafficking of ErbBs. Exp Cell Res (2009) 3.70

Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell (2009) 3.69

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway. Cancer Cell (2005) 3.67

Structural biology of nucleocytoplasmic transport. Annu Rev Biochem (2007) 3.66

Presenilin-dependent ErbB4 nuclear signaling regulates the timing of astrogenesis in the developing brain. Cell (2006) 3.42

Nuclear targeting signal recognition: a key control point in nuclear transport? Bioessays (2000) 3.17

Karyopherin-mediated import of integral inner nuclear membrane proteins. Nature (2006) 3.12

Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J Biol Chem (2005) 3.02

Importin beta: conducting a much larger cellular symphony. Mol Cell (2004) 2.75

Quantitative determination of nuclear and cytoplasmic epidermal growth factor receptor expression in oropharyngeal squamous cell cancer by using automated quantitative analysis. Clin Cancer Res (2005) 2.65

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway. Genes Dev (2008) 2.61

Nuclear EGFR contributes to acquired resistance to cetuximab. Oncogene (2009) 2.58

Blurring the boundary: the nuclear envelope extends its reach. Science (2007) 2.58

Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res (2005) 2.58

Binding at and transactivation of the COX-2 promoter by nuclear tyrosine kinase receptor ErbB-2. Cancer Cell (2004) 2.53

Tyrosine phosphorylation controls PCNA function through protein stability. Nat Cell Biol (2006) 2.45

The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone. J Cell Biol (2004) 2.41

Tracing the retrograde route in protein trafficking. Cell (2008) 2.38

Oncogenic EGFR signaling networks in glioma. Sci Signal (2009) 2.38

Characterization of a novel tripartite nuclear localization sequence in the EGFR family. J Biol Chem (2007) 2.30

c-erbB-3: a nuclear protein in mammary epithelial cells. J Cell Biol (2002) 2.27

Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor. Mol Cell Biol (2005) 2.20

Nuclear-cytoplasmic transport of EGFR involves receptor endocytosis, importin beta1 and CRM1. J Cell Biochem (2006) 2.11

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer (2006) 2.09

Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation. J Cell Biol (2001) 2.04

A novel endocytic mechanism of epidermal growth factor receptor sequestration and internalization. Cancer Res (2006) 2.01

Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression. Mol Biol Cell (2007) 1.99

EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat (2006) 1.92

Importin-alpha-16 is a translocon-associated protein involved in sorting membrane proteins to the nuclear envelope. Nat Struct Mol Biol (2006) 1.90

Membrane traffic exploited by protein toxins. Annu Rev Cell Dev Biol (2002) 1.87

Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity. Radiother Oncol (2005) 1.87

Back signaling by the Nrg-1 intracellular domain. J Cell Biol (2003) 1.85

The epidermal growth factor receptor: a role in repair of radiation-induced DNA damage. Clin Cancer Res (2007) 1.79

Co-regulation of B-Myb expression by E2F1 and EGF receptor. Mol Carcinog (2006) 1.78

Somatic EGFR mutations and efficacy of tyrosine kinase inhibitors in NSCLC. Nat Rev Clin Oncol (2009) 1.78

Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors. Clin Cancer Res (2009) 1.74

Highway to the inner nuclear membrane: rules for the road. Nat Rev Mol Cell Biol (2007) 1.71

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer. Mol Carcinog (2009) 1.71

Nuclear localization of p185neu tyrosine kinase and its association with transcriptional transactivation. Biochem Biophys Res Commun (1994) 1.71

Management of breast cancer with targeted agents: importance of heterogeneity. [corrected]. Nat Rev Clin Oncol (2010) 1.69

Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma. Cancer Res (2007) 1.68

Molecular predictors of response to trastuzumab and lapatinib in breast cancer. Nat Rev Clin Oncol (2009) 1.67

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression. Nucleic Acids Res (2008) 1.66

SUMOylation mediates the nuclear translocation and signaling of the IGF-1 receptor. Sci Signal (2010) 1.63

Cargo recognition during clathrin-mediated endocytosis: a team effort. Curr Opin Cell Biol (2004) 1.62

Retrograde transport pathways utilised by viruses and protein toxins. Virol J (2006) 1.61

Membrane-anchored growth factors, the epidermal growth factor family: beyond receptor ligands. Cancer Sci (2008) 1.60

Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes. Mol Cancer Res (2010) 1.60

Nuclear localization and possible functions of receptor tyrosine kinases. Curr Opin Cell Biol (2003) 1.53

rab7 activity affects epidermal growth factor:epidermal growth factor receptor degradation by regulating endocytic trafficking from the late endosome. J Biol Chem (2005) 1.50

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK. Mol Cancer (2008) 1.49

Nuclear expression of phosphorylated EGFR is associated with poor prognosis of patients with esophageal squamous cell carcinoma. Pathobiology (2007) 1.46

EGFR tyrosine kinase inhibitors in lung cancer: an evolving story. Annu Rev Med (2008) 1.46

Nuclear translocation of cell-surface receptors: lessons from fibroblast growth factor. Traffic (2005) 1.39

Signalling shortcuts: cell-surface receptors in the nucleus? Nat Rev Mol Cell Biol (2002) 1.39

Trafficking of receptor tyrosine kinases to the nucleus. Exp Cell Res (2008) 1.33

Regulation of EGFR endocytic trafficking by rab proteins. Histol Histopathol (2006) 1.32

Lapatinib, a dual EGFR and HER2 tyrosine kinase inhibitor, downregulates thymidylate synthase by inhibiting the nuclear translocation of EGFR and HER2. PLoS One (2009) 1.30

Localization of epidermal growth factor receptor in hepatocyte nuclei. Hepatology (1991) 1.27

Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane. J Cell Biol (2008) 1.24

The HER4/4ICD estrogen receptor coactivator and BH3-only protein is an effector of tamoxifen-induced apoptosis. Cancer Res (2008) 1.23

The developing role of receptors and adaptors. Nat Rev Cancer (2006) 1.21

ErbB4/HER4: role in mammary gland development, differentiation and growth inhibition. J Mammary Gland Biol Neoplasia (2008) 1.20

HER4 intracellular domain (4ICD) activity in the developing mammary gland and breast cancer. J Mammary Gland Biol Neoplasia (2008) 1.20

Nuclear EGFR is required for cisplatin resistance and DNA repair. Am J Transl Res (2009) 1.19

Integrative nuclear signaling in cell development--a role for FGF receptor-1. DNA Cell Biol (2007) 1.16

The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus. Cancer Res (2007) 1.13

Integrative nuclear FGFR1 signaling (INFS) pathway mediates activation of the tyrosine hydroxylase gene by angiotensin II, depolarization and protein kinase C. J Neurochem (2002) 1.13

The role of HER1-HER4 and EGFRvIII in hormone-refractory prostate cancer. Clin Cancer Res (2006) 1.12

Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism. Int J Radiat Oncol Biol Phys (2007) 1.12

Cell biology: popping out of the nucleus. Nature (2004) 1.10

Schwannoma-derived growth factor must be transported into the nucleus to exert its mitogenic activity. Proc Natl Acad Sci U S A (1993) 1.10

Nuclear trafficking of FGFR1: a role for the transmembrane domain. J Cell Biochem (2003) 1.07

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors. J Cell Biol (2005) 1.07

The whole structure of the 13-subunit oxidized cytochrome c oxidase at 2.8 A. Science (1996) 9.32

Endoscopic mucosal resection for treatment of early gastric cancer. Gut (2001) 8.70

Structures of metal sites of oxidized bovine heart cytochrome c oxidase at 2.8 A. Science (1995) 5.43

Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase. Science (1998) 5.01

Detection of a wide range of medically important fungi by the polymerase chain reaction. J Med Microbiol (1994) 4.14

Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor. Nature (1985) 3.59

IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling. Nature (2000) 3.56

A new endoscopic mucosal resection procedure using an insulation-tipped electrosurgical knife for rectal flat lesions: report of two cases. Gastrointest Endosc (1999) 3.55

Hypertrophic nonobstructive cardiomyopathy with giant negative T waves (apical hypertrophy): ventriculographic and echocardiographic features in 30 patients. Am J Cardiol (1979) 3.29

Risk factors for lymph node metastasis from intramucosal gastric carcinoma. Cancer (1996) 3.21

Metastatic tumors to the stomach: analysis of 54 patients diagnosed at endoscopy and 347 autopsy cases. Endoscopy (2001) 3.01

Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation. Neurobiol Dis (1996) 2.50

Ampulla cardiomyopathy ('Takotusbo' cardiomyopathy)--reversible left ventricular dysfunction: with ST segment elevation. Jpn Circ J (2000) 2.39

Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci U S A (1999) 2.39

The role of EZH2 in tumour progression. Br J Cancer (2011) 2.33

Combined transcriptome and proteome analysis as a powerful approach to study genes under glucose repression in Bacillus subtilis. Nucleic Acids Res (2001) 2.28

WIP regulates N-WASP-mediated actin polymerization and filopodium formation. Nat Cell Biol (2001) 2.18

Anandamide amidohydrolase reacting with 2-arachidonoylglycerol, another cannabinoid receptor ligand. FEBS Lett (1998) 2.16

DNA microarray analysis of Bacillus subtilis DegU, ComA and PhoP regulons: an approach to comprehensive analysis of B.subtilis two-component regulatory systems. Nucleic Acids Res (2001) 2.13

Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores. Plant Physiol (1999) 2.11

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br J Cancer (2006) 2.09

Validity of 18F-fluorodeoxyglucose imaging with a dual-head coincidence gamma camera for detection of myocardial viability. J Nucl Med (1999) 2.06

Mode of action of clotrimazole. Sabouraudia (1973) 2.01

Comprehensive DNA microarray analysis of Bacillus subtilis two-component regulatory systems. J Bacteriol (2001) 1.94

Antibacterial activity of essential oils and their major constituents against respiratory tract pathogens by gaseous contact. J Antimicrob Chemother (2001) 1.90

Manipulation of the small intestine as a cause of the increased inflammatory response after open compared with laparoscopic surgery. Br J Surg (2006) 1.88

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology. Nat Med (1996) 1.86

Mutations of the epigenetics-modifying gene (DNMT3a, TET2, IDH1/2) at diagnosis may induce FLT3-ITD at relapse in de novo acute myeloid leukemia. Leukemia (2012) 1.82

Phylogenetic classification and species identification of dermatophyte strains based on DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions. J Clin Microbiol (1999) 1.81

Emission of coherent THz radiation from superconductors. Science (2007) 1.78

The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br J Cancer (2006) 1.73

New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups. Antimicrob Agents Chemother (1984) 1.71

Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proc Natl Acad Sci U S A (1998) 1.71

Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax. J Biol Chem (2001) 1.70

Bit storage and bit flip operations in an electromechanical oscillator. Nat Nanotechnol (2008) 1.68

Abnormality of c-kit oncoprotein in certain patients with chronic myelogenous leukemia--potential clinical significance. Leukemia (2002) 1.68

Molecular diagnosis and epidemiology of fungal infections. Med Mycol (1998) 1.64

Minilaparotomy wound edge protector (Lap-Protector): a new device. Surg Today (2001) 1.64

Hyperfine structure of antiprotonic helium revealed by a laser-microwave-laser resonance method. Phys Rev Lett (2002) 1.62

Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. Antimicrob Agents Chemother (1990) 1.60

Polycythemia associated with the JAK2V617F mutation emerged during treatment of chronic myelogenous leukemia. Leukemia (2007) 1.53

Expression of cytokines after meniscal rasping to promote meniscal healing. Arthroscopy (2001) 1.53

Histopathologic findings predicting lymph node metastasis and prognosis of patients with superficial esophageal carcinoma: analysis of 240 surgically resected tumors. Cancer (2000) 1.53

Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am J Pathol (2000) 1.52

Oligodendroglial microtubular tangles in olivopontocerebellar atrophy. J Neuropathol Exp Neurol (1990) 1.52

The effects of biphasic and conventional monophasic defibrillation on postresuscitation myocardial function. J Am Coll Cardiol (1999) 1.50

"Myocardial stunning"-like phenomenon during a crisis of pheochromocytoma. Jpn Circ J (1994) 1.49

Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease. Am J Pathol (1996) 1.47

Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis. Circ Res (1993) 1.47

Arrhythmogenic right ventricular cardiomyopathy with an initial manifestation of severe left ventricular impairment and normal contraction of the right ventricle. Jpn Circ J (2000) 1.46

Crystal structures of the copper-containing amine oxidase from Arthrobacter globiformis in the holo and apo forms: implications for the biogenesis of topaquinone. Biochemistry (1997) 1.45

Expression of multiple cancer-testis antigen genes in gastrointestinal and breast carcinomas. Br J Cancer (2001) 1.44

Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons. Neurosci Res (1998) 1.41

Coenzyme Q10, iron, and vitamin B6 in genetically-confirmed Alzheimer's disease. Lancet (1992) 1.41

Autoimmune reactivity of sera to hepatocyte plasma membrane in type 1 autoimmune hepatitis. J Gastroenterol (2000) 1.41

Studies on the mechanism of antifungal action of aculeacin A. J Antibiot (Tokyo) (1982) 1.41

Cloning two genes for nicotianamine aminotransferase, a critical enzyme in iron acquisition (Strategy II) in graminaceous plants. Plant Physiol (1999) 1.41

Isolation, characterization, and serial propagation of a bovine group C rotavirus in a monkey kidney cell line (MA104). J Clin Microbiol (1991) 1.39

The comparison of epidural fentanyl, epidural lidocaine, and intravenous fentanyl in patients undergoing gastrectomy. Anesth Analg (1995) 1.39

Pericardio-peritoneal drainage using a subcostal approach. Jpn J Thorac Cardiovasc Surg (1999) 1.39

Intragastric endoscopic surgery using the transanal endoscopic microsurgery technique. Br J Surg (1997) 1.39

Control of dimorphism in Candida albicans by zinc: effect on cell morphology and composition. J Gen Microbiol (1975) 1.37

Determination of the strange-quark density of the proton from ATLAS measurements of the W→ℓν and Z→ℓℓ cross sections. Phys Rev Lett (2012) 1.34

Intramural metastasis of thoracic esophageal carcinoma. Int J Cancer (1992) 1.33

Crystallization and preliminary X-ray studies of Bacillus pumilus IPO xylanase. J Mol Biol (1987) 1.33

Short-homology-independent illegitimate recombination in Escherichia coli: distinct mechanism from short-homology-dependent illegitimate recombination. J Mol Biol (1997) 1.32

Thymidylate synthase as a determinant of pemetrexed sensitivity in non-small cell lung cancer. Br J Cancer (2011) 1.32

Capuramycin, a new nucleoside antibiotic. Taxonomy, fermentation, isolation and characterization. J Antibiot (Tokyo) (1986) 1.32

Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental tinea pedis in guinea pigs. Antimicrob Agents Chemother (1990) 1.31

Immunohistochemical and immunoelectron microscopic localization of S-100 protein in the interdigitating reticulum cells of the human lymph node. Virchows Arch B Cell Pathol Incl Mol Pathol (1981) 1.31

S100 protein in folliculostellate cells of the rat pituitary anterior lobe. Brain Res (1980) 1.30

Primary coronary artery dissection observed at coronary angiography. Am J Cardiol (1988) 1.30

Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100. Neurosci Lett (2002) 1.29

Species identification and strain typing of Malassezia species stock strains and clinical isolates based on the DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions. J Med Microbiol (2000) 1.29

Observation of associated near-side and away-side long-range correlations in sqrt[s(NN)]=5.02 TeV proton-lead collisions with the ATLAS detector. Phys Rev Lett (2013) 1.27

Sodium thiosulfate solution spray for relief of irritation caused by Lugol's stain in chromoendoscopy. Gastrointest Endosc (2001) 1.26

Two dioxygenase genes, Ids3 and Ids2, from Hordeum vulgare are involved in the biosynthesis of mugineic acid family phytosiderophores. Plant Mol Biol (2000) 1.26

Phylogenetic classification of Trichophyton mentagrophytes complex strains based on DNA sequences of nuclear ribosomal internal transcribed spacer 1 regions. J Clin Microbiol (1998) 1.25

Fatigue fracture of the ulna occurring in pitchers of fast-pitch softball. Am J Sports Med (1991) 1.25

Vimentin is a novel AKT1 target mediating motility and invasion. Oncogene (2010) 1.23

Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. Oncogene (2012) 1.23

Characteristics of coronary heart disease in Japanese taxi drivers as determined by coronary angiographic analyses. Ind Health (2000) 1.23

Effect of fatty acyl group and sterol composition on sensitivity of lecithin liposomes to imidazole antimycotics. Antimicrob Agents Chemother (1979) 1.23

Amyloid beta-protein precursor accumulates in dystrophic neurites of senile plaques in Alzheimer-type dementia. Brain Res (1990) 1.21

Inhibition of the SH3 domain-mediated binding of Src to the androgen receptor and its effect on tumor growth. Oncogene (2007) 1.20

In vitro antifungal activity of a novel lipopeptide antifungal agent, FK463, against various fungal pathogens. J Antibiot (Tokyo) (2000) 1.20

Down-regulation of the surface expression of class I MHC antigens by human cytomegalovirus. Virology (1993) 1.20

Dendritic cell vaccination with MAGE peptide is a novel therapeutic approach for gastrointestinal carcinomas. Clin Cancer Res (2001) 1.19

Search for dark matter candidates and large extra dimensions in events with a photon and missing transverse momentum in pp collision data at sqrt[s]=7 TeV with the ATLAS detector. Phys Rev Lett (2013) 1.19

Immunohistochemical localization of S-100 protein in granular cell myoblastoma. Cancer (1982) 1.18

Localization of S-100 protein and glial fibrillary acidic protein-related antigen in pleomorphic adenoma of the salivary glands. Lab Invest (1982) 1.18

[Studies on the immunohistochemical localization of S-100 and glial fibrillary acidic proteins in the rat nervous system and in human brain tumors (author's transl)]. No To Shinkei (1980) 1.18

Identification of fetomodulin, a surface marker protein of fetal development, as thrombomodulin by gene cloning and functional assays. Dev Biol (1990) 1.18

MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol. Oncogene (2012) 1.17

Immunohistochemical diagnosis of Cryptococcus neoformans var. gattii infection in chronic meningoencephalitis: the first case in Japan. Intern Med (2001) 1.17

Appearance of sodium dodecyl sulfate-stable amyloid beta-protein (Abeta) dimer in the cortex during aging. Am J Pathol (1999) 1.17

Relative biological effectiveness for cell-killing effect on various human cell lines irradiated with heavy-ion medical accelerator in Chiba (HIMAC) carbon-ion beams. Int J Radiat Oncol Biol Phys (2000) 1.17

Stomach-partitioning gastrojejunostomy for unresectable gastric carcinoma. Arch Surg (1997) 1.17

Clinical observation of 52 cases of aortitis syndrome. Jpn Heart J (1969) 1.16

Redifferentiation of smooth muscle cells after coronary angioplasty determined via myosin heavy chain expression. Circulation (1997) 1.16