Published in J Transl Med on May 09, 2014
The biological function and clinical utilization of CD147 in human diseases: a review of the current scientific literature. Int J Mol Sci (2014) 1.15
Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. J Cell Mol Med (2015) 0.83
Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis. Biomed Res Int (2015) 0.83
CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis. Sci Rep (2016) 0.79
Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors. Oncotarget (2015) 0.77
Characterization of acetate transport in colorectal cancer cells and potential therapeutic implications. Oncotarget (2016) 0.75
Evaluation of MCT1, MCT4 and CD147 Genes in Peripheral Blood Cells of Breast Cancer Patients and Their Potential Use as Diagnostic and Prognostic Markers. Int J Mol Sci (2017) 0.75
Hallmarks of cancer: the next generation. Cell (2011) 140.01
Notch signaling: cell fate control and signal integration in development. Science (1999) 28.83
Large-scale mapping of human protein-protein interactions by mass spectrometry. Mol Syst Biol (2007) 8.16
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest (2008) 7.52
Comparative study of the National Cancer Institute and French Federation of Cancer Centers Sarcoma Group grading systems in a population of 410 adult patients with soft tissue sarcoma. J Clin Oncol (1997) 3.60
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: a metabolic survival role for tumor-associated stroma. Cancer Res (2006) 2.68
Soft tissue sarcomas. CA Cancer J Clin (2004) 2.65
Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review. Front Pharmacol (2011) 2.24
EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie (2005) 2.10
Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer. Br J Cancer (2007) 2.00
(F-18) fluorodeoxyglucose positron emission tomography as a predictor of pathologic grade and other prognostic variables in bone and soft tissue sarcoma. Clin Cancer Res (2000) 1.89
Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas. Virchows Arch (2008) 1.71
Role of monocarboxylate transporters in human cancers: state of the art. J Bioenerg Biomembr (2012) 1.70
Reduction of glucose metabolic activity is more accurate than change in size at predicting histopathologic response to neoadjuvant therapy in high-grade soft-tissue sarcomas. Clin Cancer Res (2008) 1.62
Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene (2010) 1.60
Regulation of intracellular pH in human melanoma: potential therapeutic implications. Mol Cancer Ther (2002) 1.57
Silencing of monocarboxylate transporters via small interfering ribonucleic acid inhibits glycolysis and induces cell death in malignant glioma: an in vitro study. Neurosurgery (2004) 1.52
The SLC16 gene family - structure, role and regulation in health and disease. Mol Aspects Med (2013) 1.50
The H+-linked monocarboxylate transporter (MCT1/SLC16A1): a potential therapeutic target for high-risk neuroblastoma. Mol Pharmacol (2006) 1.49
FDG-PET/CT imaging predicts histopathologic treatment responses after the initial cycle of neoadjuvant chemotherapy in high-grade soft-tissue sarcomas. Clin Cancer Res (2009) 1.47
Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma. Histopathology (2010) 1.44
Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer. BMC Cancer (2011) 1.39
The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147. Am J Pathol (2002) 1.30
Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets. Neuro Oncol (2012) 1.29
Clinical value of [18-F]] fluorodeoxyglucose positron emission tomography imaging in soft tissue sarcomas. Ann Surg (2000) 1.29
Lung cancer: a comparative study of metabolism related protein expression in cancer cells and tumor associated stroma. Cancer Biol Ther (2007) 1.18
Increasing expression of monocarboxylate transporters 1 and 4 along progression to invasive cervical carcinoma. Int J Gynecol Pathol (2008) 1.18
Sarcoma epidemiology and etiology: potential environmental and genetic factors. Surg Clin North Am (2008) 1.17
The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer. Eur J Cancer (2009) 1.13
Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study. Neurosurgery (2006) 1.03
Monocarboxylate transporters 1 and 4 are associated with CD147 in cervical carcinoma. Dis Markers (2009) 1.01
A novel nutrient sensing mechanism underlies substrate-induced regulation of monocarboxylate transporter-1. Am J Physiol Gastrointest Liver Physiol (2012) 1.00
Correlation between glycolytic phenotype and tumor grade in soft-tissue sarcomas by 18F-FDG PET. J Nucl Med (2010) 0.93
Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia. Traffic (2011) 0.93
Transport mechanism for L-lactic acid in human myocytes using human prototypic embryonal rhabdomyosarcoma cell line (RD cells). Biol Pharm Bull (2005) 0.86
Regulation of monocarboxylate transporter 1 in skeletal muscle cells by intracellular signaling pathways. Biol Pharm Bull (2010) 0.80
Regulation of human monocarboxylate transporter 4 in skeletal muscle cells: the role of protein kinase C (PKC). Int J Pharm (2012) 0.78
Matrix metalloproteinase expression in high grade soft tissue sarcomas. Oncol Rep (2007) 0.78
Basal-like and triple-negative breast cancers: a critical review with an emphasis on the implications for pathologists and oncologists. Mod Pathol (2010) 2.42
A distinct spectrum of copy number aberrations in pediatric high-grade gliomas. Clin Cancer Res (2010) 2.37
Breast cancer prognostic classification in the molecular era: the role of histological grade. Breast Cancer Res (2010) 2.33
Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN. Cancer Discov (2013) 1.93
Lobular neoplasia of the breast revisited with emphasis on the role of E-cadherin immunohistochemistry. Am J Surg Pathol (2013) 1.83
Role of monocarboxylate transporters in human cancers: state of the art. J Bioenerg Biomembr (2012) 1.70
MicroRNA history: discovery, recent applications, and next frontiers. Mutat Res (2011) 1.66
Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res (2007) 1.61
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Lab Invest (2006) 1.59
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Res (2005) 1.59
Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice. Infect Immun (2005) 1.59
CD147 immunohistochemistry discriminates between reactive mesothelial cells and malignant mesothelioma. Diagn Cytopathol (2012) 1.51
Overexpression of platelet-derived growth factor receptor alpha in breast cancer is associated with tumour progression. Breast Cancer Res (2005) 1.47
Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development. PLoS One (2009) 1.44
MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature. Cancer Res (2010) 1.40
Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer. BMC Cancer (2011) 1.39
Mutation analysis of B-RAF gene in human gliomas. Acta Neuropathol (2004) 1.39
Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells. Gastroenterology (2012) 1.38
P-cadherin overexpression is an indicator of clinical outcome in invasive breast carcinomas and is associated with CDH3 promoter hypomethylation. Clin Cancer Res (2005) 1.36
Expression of monocarboxylate transporters 1, 2, and 4 in human tumours and their association with CD147 and CD44. J Biomed Biotechnol (2010) 1.32
Phase II and pharmacogenomics study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme and gliosarcoma. Neuro Oncol (2011) 1.31
Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets. Neuro Oncol (2012) 1.29
Distribution and significance of nerve growth factor receptor (NGFR/p75NTR) in normal, benign and malignant breast tissue. Mod Pathol (2006) 1.28
EGFRvIII deletion mutations in pediatric high-grade glioma and response to targeted therapy in pediatric glioma cell lines. Clin Cancer Res (2009) 1.24
Distribution of p63, cytokeratins 5/6 and cytokeratin 14 in 51 normal and 400 neoplastic human tissue samples using TARP-4 multi-tumor tissue microarray. Virchows Arch (2003) 1.24
Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res (2013) 1.23
p63 expression in normal skin and usual cutaneous carcinomas. J Cutan Pathol (2002) 1.22
Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma. Cancer Res (2010) 1.21
Synthesis and antioxidant properties of new chromone derivatives. Bioorg Med Chem (2009) 1.20
Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast. Appl Immunohistochem Mol Morphol (2003) 1.15
P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ. Virchows Arch (2006) 1.13
Desmoplastic small round cell tumour: Cytological and immunocytochemical features. Cytojournal (2005) 1.12
P-cadherin expression in breast cancer: a review. Breast Cancer Res (2007) 1.09
EGFR/HER2 in breast cancer: a biological approach for molecular diagnosis and therapy. Expert Rev Mol Diagn (2008) 1.09
The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β. Genes Dev (2013) 1.08
Mixed micropapillary-ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components. J Pathol (2009) 1.08
Lymphatic vessel density and epithelial D2-40 immunoreactivity in pre-invasive and invasive lesions of the uterine cervix. Gynecol Oncol (2007) 1.06
Portuguese students' knowledge of antibiotics: a cross-sectional study of secondary school and university students in Braga. BMC Public Health (2009) 1.05
Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas. PLoS One (2012) 1.04
Pediatric pigmented dermatofibrosarcoma protuberans (Bednár tumor): case report and review of the literature with emphasis on the differential diagnosis. Pathol Res Pract (2002) 1.02
Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs). J Bioenerg Biomembr (2012) 1.00
17 beta -estradiol-mediated vessel assembly and stabilization in tumor angiogenesis requires TGF beta and EGFR crosstalk. Angiogenesis (2003) 1.00
Prognostic value of MGMT promoter methylation in glioblastoma patients treated with temozolomide-based chemoradiation: a Portuguese multicentre study. Oncol Rep (2010) 0.99
Taking advantage of basic research: p63 is a reliable myoepithelial and stem cell marker. Adv Anat Pathol (2002) 0.99
Molecular alterations of KIT oncogene in gliomas. Cell Oncol (2007) 0.99
Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature. J Cutan Pathol (2002) 0.98
Molecular characterization of EGFR, PDGFRA and VEGFR2 in cervical adenosquamous carcinoma. BMC Cancer (2009) 0.98
Maspin expression in normal skin and usual cutaneous carcinomas. Virchows Arch (2002) 0.97
Distribution of p63, a novel myoepithelial marker, in fine-needle aspiration biopsies of the breast: an analysis of 82 samples. Cancer (2003) 0.95
Butyrate activates the monocarboxylate transporter MCT4 expression in breast cancer cells and enhances the antitumor activity of 3-bromopyruvate. J Bioenerg Biomembr (2012) 0.95
Insights into angiogenesis in non-small cell lung cancer: molecular mechanisms, polymorphic genes, and targeted therapies. Recent Pat Anticancer Drug Discov (2012) 0.95
Vascular endothelial growth factor, transforming growth factor-alpha, and estrogen receptors: possible cross-talks and interactions. Am J Pathol (2002) 0.92
Expression of p53, Ki-67 and c-erb B2 in growth hormone-and/or prolactin-secreting pituitary adenomas. Arq Neuropsiquiatr (2006) 0.92
Pathologic quiz case: a 62-year-old woman with a 4.5-cm nodule in the right breast. Lipid-rich breast carcinoma. Arch Pathol Lab Med (2003) 0.92
DNA copy number profiles of gastric cancer precursor lesions. BMC Genomics (2007) 0.91
How useful is the assessment of lymphatic vascular density in oral carcinoma prognosis? World J Surg Oncol (2007) 0.91
Lymphangiogenesis in tumors: what do we know? Microsc Res Tech (2003) 0.90
Angiogenesis and breast cancer. J Oncol (2010) 0.90
Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation. PLoS One (2011) 0.89
VEGFR-3 expression in breast cancer tissue is not restricted to lymphatic vessels. Pathol Res Pract (2005) 0.89
U-2940, a human B-cell line derived from a diffuse large cell lymphoma sequential to Hodgkin lymphoma. Int J Cancer (2006) 0.89
Molecular characterization of PDGFR-alpha/PDGF-A and c-KIT/SCF in gliosarcomas. Cell Oncol (2005) 0.88
Primary epithelial malignant mesothelioma of the pericardium with deciduoid features: cytohistologic and immunohistochemical study. Diagn Cytopathol (2002) 0.88
KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas. J Neuropathol Exp Neurol (2015) 0.87
Mixed gastric carcinomas show similar chromosomal aberrations in both their diffuse and glandular components. Cell Oncol (2006) 0.87
Molecular analysis of c-Kit and PDGFRA in GISTs diagnosed by EUS. Am J Clin Pathol (2007) 0.87
The monocarboxylate transporter inhibitor α-cyano-4-hydroxycinnamic acid disrupts rat lung branching. Cell Physiol Biochem (2013) 0.86
Molecular profiling, including TERT promoter mutations, of acral lentiginous melanomas. Melanoma Res (2016) 0.86
Differential sensitivities to lactate transport inhibitors of breast cancer cell lines. Endocr Relat Cancer (2013) 0.86
TP53 germline mutations in Portugal and genetic modifiers of age at cancer onset. Fam Cancer (2009) 0.86
Impact of EGFR genetic variants on glioma risk and patient outcome. Cancer Epidemiol Biomarkers Prev (2011) 0.86
Ki-67 and CD100 immunohistochemical expression is associated with local recurrence and poor prognosis in soft tissue sarcomas, respectively. Oncol Lett (2013) 0.85
Role of endoglin and VEGF family expression in colorectal cancer prognosis and anti-angiogenic therapies. World J Clin Oncol (2011) 0.85
Analysis of waveform-derived ORA parameters in early forms of keratoconus and normal corneas. J Refract Surg (2013) 0.85
Molecular evidence in support of the neoplastic and precursor nature of microglandular adenosis. Histopathology (2012) 0.85
Assessing the impact of a school intervention to promote students' knowledge and practices on correct antibiotic use. Int J Environ Res Public Health (2013) 0.85
Low RKIP expression associates with poor prognosis in bladder cancer patients. Virchows Arch (2013) 0.84
Glucose Addiction in Cancer Therapy: Advances and Drawbacks. Curr Drug Metab (2015) 0.84
Immunoexpression of Ezrin and CD44 in patients with osteosarcoma. J Pediatr Hematol Oncol (2010) 0.84
MicroRNAs and metastases--the neuroblastoma link. Cancer Biol Ther (2010) 0.83
Self-interaction of human Pex11pβ during peroxisomal growth and division. PLoS One (2013) 0.83
KIT activation in uterine cervix adenosquamous carcinomas by KIT/SCF autocrine/paracrine stimulation loops. Gynecol Oncol (2008) 0.83
Localization of MCT2 at peroxisomes is associated with malignant transformation in prostate cancer. J Cell Mol Med (2015) 0.83
Fine-needle aspiration cytology of pulmonary rheumatoid nodule: case report and review of the major cytologic features. Diagn Cytopathol (2002) 0.83
The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma. Acta Neuropathol Commun (2014) 0.82
Cyclooxygenase-2 and epidermal growth factor receptor expressions in different histological subtypes of cervical carcinomas. Int J Gynecol Pathol (2007) 0.82
Long term outcome of otosclerosis surgery. Braz J Otorhinolaryngol (2012) 0.81
Maspin is expressed in the nuclei of breast myoepithelial cells. J Pathol (2002) 0.81
Angiogenic potential of gellan-gum-based hydrogels for application in nucleus pulposus regeneration: in vivo study. Tissue Eng Part A (2012) 0.81
Peritumoural, but not intratumoural, lymphatic vessel density and invasion correlate with colorectal carcinoma poor-outcome markers. Virchows Arch (2007) 0.81