Published in Mol Microbiol on May 12, 2010
Evolving New Protein-Protein Interaction Specificity through Promiscuous Intermediates. Cell (2015) 2.21
Diversity of bacterial type II toxin-antitoxin systems: a comprehensive search and functional analysis of novel families. Nucleic Acids Res (2011) 2.19
Toxin-antitoxin systems as multilevel interaction systems. Toxins (Basel) (2014) 1.36
Toxin-antitoxin systems are important for niche-specific colonization and stress resistance of uropathogenic Escherichia coli. PLoS Pathog (2012) 1.22
ppGpp and polyphosphate modulate cell cycle progression in Caulobacter crescentus. J Bacteriol (2011) 1.14
Structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria. Proc Natl Acad Sci U S A (2012) 1.00
Regulating toxin-antitoxin expression: controlled detonation of intracellular molecular timebombs. Toxins (Basel) (2014) 1.00
The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment. Mol Microbiol (2011) 0.98
Transcriptional cross-activation between toxin-antitoxin systems of Escherichia coli. BMC Microbiol (2013) 0.96
The Brucella abortus general stress response system regulates chronic mammalian infection and is controlled by phosphorylation and proteolysis. J Biol Chem (2013) 0.96
The three vibrio cholerae chromosome II-encoded ParE toxins degrade chromosome I following loss of chromosome II. J Bacteriol (2010) 0.93
The HicA toxin from Burkholderia pseudomallei has a role in persister cell formation. Biochem J (2014) 0.88
Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus. J Biol Chem (2012) 0.85
Chromosome replication and segregation govern the biogenesis and inheritance of inorganic polyphosphate granules. Mol Biol Cell (2013) 0.83
Comprehensive Functional Analysis of the 18 Vibrio cholerae N16961 Toxin-Antitoxin Systems Substantiates Their Role in Stabilizing the Superintegron. J Bacteriol (2015) 0.82
WrpA Is an Atypical Flavodoxin Family Protein under Regulatory Control of the Brucella abortus General Stress Response System. J Bacteriol (2016) 0.81
Structured and Dynamic Disordered Domains Regulate the Activity of a Multifunctional Anti-σ Factor. MBio (2015) 0.80
myo-inositol and D-ribose ligand discrimination in an ABC periplasmic binding protein. J Bacteriol (2013) 0.80
Cell growth inhibition upon deletion of four toxin-antitoxin loci from the megaplasmids of Sinorhizobium meliloti. J Bacteriol (2013) 0.80
Linkage, mobility, and selfishness in the MazF family of bacterial toxins: a snapshot of bacterial evolution. Genome Biol Evol (2013) 0.79
Recovery of plasmid pEMB1, whose toxin-antitoxin system stabilizes an ampicillin resistance-conferring β-lactamase gene in Escherichia coli, from natural environments. Appl Environ Microbiol (2014) 0.78
Intergenerational continuity of cell shape dynamics in Caulobacter crescentus. Sci Rep (2015) 0.77
Transcriptomic analysis of the stationary phase response regulator SpdR in Caulobacter crescentus. BMC Microbiol (2016) 0.76
Growth control switch by a DNA-damage-inducible toxin-antitoxin system in Caulobacter crescentus. Nat Microbiol (2016) 0.76
Identification and characterization of a HEPN-MNT family type II toxin-antitoxin in Shewanella oneidensis. Microb Biotechnol (2015) 0.76
Identification and characterization of chromosomal relBE toxin-antitoxin locus in Streptomyces cattleya DSM46488. Sci Rep (2016) 0.76
CspC regulates the expression of the glyoxylate cycle genes at stationary phase in Caulobacter. BMC Genomics (2015) 0.76
The Chromosomal parDE2 Toxin-Antitoxin System of Mycobacterium tuberculosis H37Rv: Genetic and Functional Characterization. Front Microbiol (2016) 0.75
Conserved ABC Transport System Regulated by the General Stress Response Pathways of Alpha- and Gammaproteobacteria. J Bacteriol (2017) 0.75
Characterization of the Deep-Sea Streptomyces sp. SCSIO 02999 Derived VapC/VapB Toxin-Antitoxin System in Escherichia coli. Toxins (Basel) (2016) 0.75
Characterization of Toxin-Antitoxin (TA) Systems in Pseudomonas aeruginosa Clinical Isolates in Iran. Jundishapur J Microbiol (2016) 0.75
Evolutionary diversification of protein-protein interactions by interface add-ons. Proc Natl Acad Sci U S A (2017) 0.75
A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions. Nucleic Acids Res (1988) 26.70
CD-Search: protein domain annotations on the fly. Nucleic Acids Res (2004) 16.76
Prokaryotic toxin-antitoxin stress response loci. Nat Rev Microbiol (2005) 9.08
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res (2005) 6.61
Genetics of Caulobacter crescentus. Methods Enzymol (1991) 6.22
The bacterial toxin RelE displays codon-specific cleavage of mRNAs in the ribosomal A site. Cell (2003) 6.01
An nptI-sacB-sacR cartridge for constructing directed, unmarked mutations in gram-negative bacteria by marker exchange-eviction mutagenesis. Gene (1987) 5.25
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells. Proc Natl Acad Sci U S A (1986) 5.00
Integrons: agents of bacterial evolution. Nat Rev Microbiol (2006) 4.81
Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrest. Science (2003) 4.55
RelE, a global inhibitor of translation, is activated during nutritional stress. Proc Natl Acad Sci U S A (2001) 4.10
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA. J Mol Biol (2003) 3.76
Bacterial programmed cell death and multicellular behavior in bacteria. PLoS Genet (2006) 3.56
RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA. Mol Microbiol (2003) 3.32
Programmed cell death in bacteria: proteic plasmid stabilization systems. Mol Microbiol (1995) 3.21
Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct (2009) 3.17
Effects of the ccd function of the F plasmid on bacterial growth. J Bacteriol (1985) 3.10
Bacterial toxin-antitoxin systems: more than selfish entities? PLoS Genet (2009) 3.03
Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxin systems: implications for pathogenesis, stress responses, and evolution. PLoS Genet (2009) 2.89
Stable inheritance of plasmid R1 requires two different loci. J Bacteriol (1985) 2.78
New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay system. Genome Biol (2003) 2.77
A developmentally regulated Caulobacter flagellar promoter is activated by 3' enhancer and IHF binding elements. Mol Biol Cell (1992) 2.61
Axe-Txe, a broad-spectrum proteic toxin-antitoxin system specified by a multidrug-resistant, clinical isolate of Enterococcus faecium. Mol Microbiol (2003) 2.58
A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus. Nucleic Acids Res (2007) 2.48
ParE toxin encoded by the broad-host-range plasmid RK2 is an inhibitor of Escherichia coli gyrase. Mol Microbiol (2002) 2.25
Addiction protein Phd of plasmid prophage P1 is a substrate of the ClpXP serine protease of Escherichia coli. Proc Natl Acad Sci U S A (1995) 2.16
Lon-dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria. Mol Microbiol (1994) 2.02
The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell (2009) 2.01
Chromosomal toxin-antitoxin loci can diminish large-scale genome reductions in the absence of selection. Mol Microbiol (2007) 1.86
The stable maintenance system pem of plasmid R100: degradation of PemI protein may allow PemK protein to inhibit cell growth. J Bacteriol (1992) 1.78
The parDE operon of the broad-host-range plasmid RK2 specifies growth inhibition associated with plasmid loss. J Mol Biol (1994) 1.62
Whole-genome transcriptional analysis of heavy metal stresses in Caulobacter crescentus. J Bacteriol (2005) 1.49
Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2. J Bacteriol (1992) 1.48
Transcriptional profiling of Caulobacter crescentus during growth on complex and minimal media. J Bacteriol (2004) 1.46
Chromosomal toxin-antitoxin systems may act as antiaddiction modules. J Bacteriol (2008) 1.46
New broad-host-range promoter probe vectors based on the plasmid RK2 replicon. FEMS Microbiol Lett (2001) 1.37
Functional interactions between coexisting toxin-antitoxin systems of the ccd family in Escherichia coli O157:H7. J Bacteriol (2007) 1.22
The yefM-yoeB toxin-antitoxin systems of Escherichia coli and Streptococcus pneumoniae: functional and structural correlation. J Bacteriol (2006) 1.12
Tightly regulated and heritable division control in single bacterial cells. Biophys J (2008) 1.10
The anti-toxin ParD of plasmid RK2 consists of two structurally distinct moieties and belongs to the ribbon-helix-helix family of DNA-binding proteins. Biochem J (2002) 1.06
A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex. Biochemistry (2010) 1.05
Characteristics and significance of DNA binding activity of plasmid stabilization protein ParD from the broad host-range plasmid RK2. J Biol Chem (1993) 1.04
Genetic and computational identification of a conserved bacterial metabolic module. PLoS Genet (2008) 0.95
Ligand-binding PAS domains in a genomic, cellular, and structural context. Annu Rev Microbiol (2011) 1.99
A photosensory two-component system regulates bacterial cell attachment. Proc Natl Acad Sci U S A (2007) 1.64
Primary reactions of the LOV2 domain of phototropin, a plant blue-light photoreceptor. Biochemistry (2003) 1.46
The genetic basis of laboratory adaptation in Caulobacter crescentus. J Bacteriol (2010) 1.45
Short hydrogen bonds in photoactive yellow protein. Acta Crystallogr D Biol Crystallogr (2004) 1.40
Function, structure and mechanism of bacterial photosensory LOV proteins. Nat Rev Microbiol (2011) 1.35
Bacterial lifestyle shapes stringent response activation. Trends Microbiol (2013) 1.26
ppGpp and polyphosphate modulate cell cycle progression in Caulobacter crescentus. J Bacteriol (2011) 1.14
The LovK-LovR two-component system is a regulator of the general stress pathway in Caulobacter crescentus. J Bacteriol (2012) 1.13
Tightly regulated and heritable division control in single bacterial cells. Biophys J (2008) 1.10
Photoregulation in prokaryotes. Curr Opin Microbiol (2008) 1.09
The LOV2 domain of phototropin: a reversible photochromic switch. J Am Chem Soc (2004) 1.08
An analysis of the solution structure and signaling mechanism of LovK, a sensor histidine kinase integrating light and redox signals. Biochemistry (2010) 1.07
A structural model of anti-anti-σ inhibition by a two-component receiver domain: the PhyR stress response regulator. Mol Microbiol (2010) 1.06
A conserved mode of protein recognition and binding in a ParD-ParE toxin-antitoxin complex. Biochemistry (2010) 1.05
Minimally invasive determination of mRNA concentration in single living bacteria. Nucleic Acids Res (2008) 1.02
Structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria. Proc Natl Acad Sci U S A (2012) 1.00
The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment. Mol Microbiol (2011) 0.98
The Brucella abortus general stress response system regulates chronic mammalian infection and is controlled by phosphorylation and proteolysis. J Biol Chem (2013) 0.96
Genetic and computational identification of a conserved bacterial metabolic module. PLoS Genet (2008) 0.95
The Brucella abortus virulence regulator, LovhK, is a sensor kinase in the general stress response signalling pathway. Mol Microbiol (2014) 0.91
Two-component signaling systems and cell cycle control in Caulobacter crescentus. Adv Exp Med Biol (2008) 0.90
Model-based deconvolution of cell cycle time-series data reveals gene expression details at high resolution. PLoS Comput Biol (2009) 0.90
Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens. MBio (2014) 0.88
The photobiology of microbial pathogenesis. PLoS Pathog (2009) 0.87
An analytical approach to bistable biological circuit discrimination using real algebraic geometry. J R Soc Interface (2015) 0.86
Phase resetting reveals network dynamics underlying a bacterial cell cycle. PLoS Comput Biol (2012) 0.86
Molecular structure and function of the novel BrnT/BrnA toxin-antitoxin system of Brucella abortus. J Biol Chem (2012) 0.85
Chromosome replication and segregation govern the biogenesis and inheritance of inorganic polyphosphate granules. Mol Biol Cell (2013) 0.83
Single-gene tuning of Caulobacter cell cycle period and noise, swarming motility, and surface adhesion. Mol Syst Biol (2010) 0.83
Electronic and protein structural dynamics of a photosensory histidine kinase. Biochemistry (2010) 0.82
myo-inositol and D-ribose ligand discrimination in an ABC periplasmic binding protein. J Bacteriol (2013) 0.80
The primary photophysics of the Avena sativa phototropin 1 LOV2 domain observed with time-resolved emission spectroscopy. Photochem Photobiol (2011) 0.78
Molecular structure of the Brucella abortus metalloprotein RicA, a Rab2-binding virulence effector. Biochemistry (2013) 0.77
Microbiology. A bacterial pathogen sees the light. Science (2007) 0.77
High-resolution computational imaging of leaf hair patterning using polarized light microscopy. Plant J (2013) 0.76
Bacterial moving and shaking: the 11th blast meeting. Mol Microbiol (2011) 0.75