Published in BMC Biol on April 19, 2010
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Positive and negative regulation of Gli activity by Kif7 in the zebrafish embryo. PLoS Genet (2013) 0.93
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Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis. J Biol Chem (2013) 0.90
Vertebrate Hedgehog signaling: cilia rule. BMC Biol (2010) 0.88
The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1. J Biol Chem (2011) 0.87
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Stabilization of speckle-type POZ protein (Spop) by Daz interacting protein 1 (Dzip1) is essential for Gli turnover and the proper output of Hedgehog signaling. J Biol Chem (2013) 0.83
The PCP protein Vangl2 regulates migration of hindbrain motor neurons by acting in floor plate cells, and independently of cilia function. Dev Biol (2013) 0.82
Growth Arrest Specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling. J Biol Chem (2011) 0.81
N-cadherin-mediated cell adhesion restricts cell proliferation in the dorsal neural tube. Mol Biol Cell (2011) 0.81
miR-219 regulates neural progenitors by dampening apical Par protein-dependent Hedgehog signaling. Development (2016) 0.77
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Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease. Sci Rep (2012) 0.76
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BAR Domain-Containing FAM92 Proteins Interact with Chibby1 To Facilitate Ciliogenesis. Mol Cell Biol (2016) 0.75
DAZ interacting protein 1 (Dzip1) phosphorylation by Polo-like kinase 1 (Plk1) regulates the centriolar satellites localization of the BBSome during the cell cycle. J Biol Chem (2016) 0.75
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Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function. PLoS Genet (2005) 6.15
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Cilia-driven fluid flow in the zebrafish pronephros, brain and Kupffer's vesicle is required for normal organogenesis. Development (2005) 4.64
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development (2005) 4.32
Disruption of the basal body compromises proteasomal function and perturbs intracellular Wnt response. Nat Genet (2007) 4.24
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The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol (2009) 2.63
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev (2009) 2.59
Foxj1 transcription factors are master regulators of the motile ciliogenic program. Nat Genet (2008) 2.58
Hedgehog-regulated Costal2-kinase complexes control phosphorylation and proteolytic processing of Cubitus interruptus. Dev Cell (2005) 2.50
Zebrafish smoothened functions in ventral neural tube specification and axon tract formation. Development (2001) 2.26
The zebrafish slow-muscle-omitted gene product is required for Hedgehog signal transduction and the development of slow muscle identity. Development (2000) 2.25
Planarian Hh signaling regulates regeneration polarity and links Hh pathway evolution to cilia. Science (2009) 2.25
Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr Biol (2003) 2.17
Divergence of hedgehog signal transduction mechanism between Drosophila and mammals. Dev Cell (2006) 2.12
Identification of signaling pathways regulating primary cilium length and flow-mediated adaptation. Curr Biol (2010) 2.08
Analysis of the zebrafish smoothened mutant reveals conserved and divergent functions of hedgehog activity. Development (2001) 2.05
The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal (2009) 2.05
The zebrafish fleer gene encodes an essential regulator of cilia tubulin polyglutamylation. Mol Biol Cell (2007) 2.05
Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling. Proc Natl Acad Sci U S A (2009) 1.95
Dampened Hedgehog signaling but normal Wnt signaling in zebrafish without cilia. Development (2009) 1.93
Left-right pattern of cardiac BMP4 may drive asymmetry of the heart in zebrafish. Development (1997) 1.84
Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes Dev (1999) 1.77
Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly. J Cell Biol (2004) 1.73
The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation. Development (2009) 1.45
A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development (2005) 1.45
The extracellular domain of Smoothened regulates ciliary localization and is required for high-level Hh signaling. Curr Biol (2009) 1.39
The Zn finger protein Iguana impacts Hedgehog signaling by promoting ciliogenesis. Dev Biol (2009) 1.38
iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes Dev (2004) 1.36
The zebrafish iguana locus encodes Dzip1, a novel zinc-finger protein required for proper regulation of Hedgehog signaling. Development (2004) 1.34
An artificial promoter construct for heat-inducible misexpression during fish embryogenesis. Dev Biol (2004) 1.32
Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development. Mol Cell Biol (2005) 1.31
The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear. Nature (2008) 1.31
Adenylate cyclase regulates elongation of mammalian primary cilia. Exp Cell Res (2009) 1.27
Zebrafish ift57, ift88, and ift172 intraflagellar transport mutants disrupt cilia but do not affect hedgehog signaling. Dev Dyn (2009) 1.18
Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2. BMC Dev Biol (2002) 1.14
Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway. BMC Dev Biol (2008) 1.12
Expression of ptc and gli genes in talpid3 suggests bifurcation in Shh pathway. Development (1999) 1.09
The iguana/DZIP1 protein is a novel component of the ciliogenic pathway essential for axonemal biogenesis. Dev Dyn (2010) 1.02
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Phosphorylation of the atypical kinesin Costal2 by the kinase Fused induces the partial disassembly of the Smoothened-Fused-Costal2-Cubitus interruptus complex in Hedgehog signalling. Development (2007) 0.99
Developmental roles and clinical significance of hedgehog signaling. Curr Top Dev Biol (2003) 5.40
A transgenic zebrafish model of neutrophilic inflammation. Blood (2006) 3.93
Efficient target-selected mutagenesis in zebrafish. Genome Res (2003) 3.61
A systematic genome-wide analysis of zebrafish protein-coding gene function. Nature (2013) 3.52
Multiple muscle cell identities induced by distinct levels and timing of hedgehog activity in the zebrafish embryo. Curr Biol (2003) 2.17
The B-cell maturation factor Blimp-1 specifies vertebrate slow-twitch muscle fiber identity in response to Hedgehog signaling. Nat Genet (2003) 2.11
Pivotal Advance: Pharmacological manipulation of inflammation resolution during spontaneously resolving tissue neutrophilia in the zebrafish. J Leukoc Biol (2010) 2.08
Retinoic acid signaling restricts the cardiac progenitor pool. Science (2005) 1.95
Regulation of stem cell maintenance and transit amplifying cell proliferation by tgf-beta signaling in Drosophila spermatogenesis. Curr Biol (2003) 1.73
Expression of multiple slow myosin heavy chain genes reveals a diversity of zebrafish slow twitch muscle fibres with differing requirements for Hedgehog and Prdm1 activity. Development (2008) 1.52
Prdm1- and Sox6-mediated transcriptional repression specifies muscle fibre type in the zebrafish embryo. EMBO Rep (2008) 1.50
A homologue of the Drosophila kinesin-like protein Costal2 regulates Hedgehog signal transduction in the vertebrate embryo. Development (2005) 1.45
A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion. Development (2007) 1.39
iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo. Genes Dev (2004) 1.36
Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures. Dis Model Mech (2012) 1.27
Modeling cardiovascular disease in the zebrafish. Trends Cardiovasc Med (2008) 1.19
Hedgehogs tryst with the cell cycle. J Cell Sci (2002) 1.18
The transformation of the model organism: a decade of developmental genetics. Nat Genet (2003) 1.17
Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling. Elife (2013) 1.15
Drosophila melanogaster as a model host for Staphylococcus aureus infection. Microbiology (2004) 1.11
Targeted mutation of the talpid3 gene in zebrafish reveals its conserved requirement for ciliogenesis and Hedgehog signalling across the vertebrates. Development (2011) 1.10
The adventures of Sonic Hedgehog in development and repair. I. Hedgehog signaling in gastrointestinal development and disease. Am J Physiol Gastrointest Liver Physiol (2007) 1.10
Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion. Development (2013) 1.08
Microcephalin coordinates mitosis in the syncytial Drosophila embryo. J Cell Sci (2007) 1.07
Analysis of Pax7 expressing myogenic cells in zebrafish muscle development, injury, and models of disease. Dev Dyn (2011) 1.06
Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases. ACS Chem Biol (2013) 1.04
Modeling inflammation in the zebrafish: how a fish can help us understand lung disease. Exp Lung Res (2007) 1.02
Prdm1a and miR-499 act sequentially to restrict Sox6 activity to the fast-twitch muscle lineage in the zebrafish embryo. Development (2011) 1.01
Sdf1a patterns zebrafish melanophores and links the somite and melanophore pattern defects in choker mutants. Development (2007) 1.01
Signalling change: signal transduction through the decades. Nat Rev Mol Cell Biol (2013) 0.99
Divergence of zebrafish and mouse lymphatic cell fate specification pathways. Development (2014) 0.98
Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing. Dev Biol (2002) 0.95
Ischemia is not required for arteriogenesis in zebrafish embryos. Arterioscler Thromb Vasc Biol (2007) 0.94
Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development (2011) 0.93
Hedgehog signalling is required for cloacal development in the zebrafish embryo. Int J Dev Biol (2009) 0.92
Microarray profiling reveals CXCR4a is downregulated by blood flow in vivo and mediates collateral formation in zebrafish embryos. Physiol Genomics (2009) 0.91
The extracellular matrix protein TGFBI promotes myofibril bundling and muscle fibre growth in the zebrafish embryo. Dev Dyn (2009) 0.90
Control of muscle fibre-type diversity during embryonic development: the zebrafish paradigm. Mech Dev (2013) 0.89
Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood (2012) 0.88
Inhibitors of neutrophil recruitment identified using transgenic zebrafish to screen a natural product library. Dis Model Mech (2013) 0.86
Factors associated with high levels of patient satisfaction with pain management. Acad Emerg Med (2012) 0.86
TigarB causes mitochondrial dysfunction and neuronal loss in PINK1 deficiency. Ann Neurol (2013) 0.85
Evolution of the Alx homeobox gene family: parallel retention and independent loss of the vertebrate Alx3 gene. Evol Dev (2011) 0.85
Expression of patched, prdm1 and engrailed in the lamprey somite reveals conserved responses to Hedgehog signaling. Evol Dev (2009) 0.85
Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. J Immunol (2014) 0.85
Collagen XV, a novel factor in zebrafish notochord differentiation and muscle development. Dev Biol (2008) 0.84
Tardbpl splicing rescues motor neuron and axonal development in a mutant tardbp zebrafish. Hum Mol Genet (2013) 0.84
Hedgehog signaling in the Drosophila eye and head: an analysis of the effects of different patched trans-heterozygotes. Genetics (2003) 0.83
Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish. Biol Open (2013) 0.80
Drugging Hedgehog: signaling the pathway to translation. BMC Biol (2013) 0.78
NICE guidance on bevacizumab in combination with paclitaxel and carboplatin for the first-line treatment of advanced ovarian cancer. Lancet Oncol (2013) 0.78
NICE guidance on bevacizumab in combination with gemcitabine and carboplatin for treating the first recurrence of platinum-sensitive advanced ovarian cancer. Lancet Oncol (2013) 0.78
Conservation of upstream regulators of scute on the notum of cyclorraphous Diptera. Dev Genes Evol (2006) 0.78
Expression screening and annotation of a zebrafish myoblast cDNA library. Gene Expr Patterns (2008) 0.77
Zebrafish models of the immune response: taking it on the ChIn. BMC Biol (2010) 0.76
On the origin of SCPP genes. Evol Dev (2014) 0.75
Small-scale marker-based screening for mutations in zebrafish development. Methods Mol Biol (2008) 0.75
MoD Special Issue celebrating 100 years since "On Growth and Form" by D'Arcy Wentworth Thompson. Mech Dev (2017) 0.75