PubRank

Cliff J Luke

Author PubWeight™ 15.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin Z. PLoS One 2010 1.62
2 Serpins flex their muscle: I. Putting the clamps on proteolysis in diverse biological systems. J Biol Chem 2010 1.32
3 Prostasin expression is regulated by airway surface liquid volume and is increased in cystic fibrosis. Am J Physiol Lung Cell Mol Physiol 2008 1.21
4 Serpins flex their muscle: II. Structural insights into target peptidase recognition, polymerization, and transport functions. J Biol Chem 2010 1.14
5 Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans. Pediatr Res 2009 1.07
6 A pro-cathepsin L mutant is a luminal substrate for endoplasmic-reticulum-associated degradation in C. elegans. PLoS One 2012 0.97
7 The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases. Biochemistry 2002 0.97
8 SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins. J Biol Chem 2004 0.92
9 The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases. Genomics 2004 0.92
10 SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change. J Biol Chem 2007 0.87
11 Using C. elegans to identify the protease targets of serpins in vivo. Methods Enzymol 2011 0.80
12 The Caenorhabditis elegans muscle specific serpin, SRP-3, neutralizes chymotrypsin-like serine peptidases. Biochemistry 2006 0.79
13 Necrotic cell death: harnessing the Dark side of the Force in mammary gland involution. Nat Cell Biol 2011 0.79
14 A small conductance calcium-activated K+ channel in C. elegans, KCNL-2, plays a role in the regulation of the rate of egg-laying. PLoS One 2013 0.78
15 Identification and activity of a lower eukaryotic serine proteinase inhibitor (serpin) from Cyanea capillata: analysis of a jellyfish serpin, jellypin. Biochemistry 2004 0.78