PubRank

Volker Lohmann

Author PubWeight™ 88.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons. J Virol 2003 5.41
2 Persistent and transient replication of full-length hepatitis C virus genomes in cell culture. J Virol 2002 5.21
3 Characterization of the early steps of hepatitis C virus infection by using luciferase reporter viruses. J Virol 2006 3.75
4 Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees. Proc Natl Acad Sci U S A 2002 3.43
5 Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment. Cell Host Microbe 2011 3.05
6 Quantitative analysis of the hepatitis C virus replication complex. J Virol 2005 2.91
7 Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs. Hepatology 2002 2.53
8 The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response. Hepatology 2010 2.52
9 Assembly of infectious hepatitis C virus particles. Trends Microbiol 2010 2.36
10 Analysis of hepatitis C virus superinfection exclusion by using novel fluorochrome gene-tagged viral genomes. J Virol 2007 2.29
11 A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C. J Virol Methods 2003 1.96
12 Essential role of cyclophilin A for hepatitis C virus replication and virus production and possible link to polyprotein cleavage kinetics. PLoS Pathog 2009 1.94
13 Multiple effects of silymarin on the hepatitis C virus lifecycle. Hepatology 2010 1.92
14 The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection. Nat Rev Microbiol 2013 1.88
15 Identification of hepatoprotective flavonolignans from silymarin. Proc Natl Acad Sci U S A 2010 1.67
16 Mouse hepatic cells support assembly of infectious hepatitis C virus particles. Gastroenterology 2011 1.64
17 Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication. J Biol Chem 2005 1.63
18 Production of infectious genotype 1b virus particles in cell culture and impairment by replication enhancing mutations. PLoS Pathog 2009 1.56
19 The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment. J Virol 2002 1.56
20 Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I). J Biol Chem 2011 1.54
21 Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication. Hepatology 2012 1.49
22 Identification of determinants involved in initiation of hepatitis C virus RNA synthesis by using intergenotypic replicase chimeras. J Virol 2007 1.44
23 Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line. J Virol 2005 1.41
24 Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model. Gastroenterology 2008 1.40
25 Role of annexin A2 in the production of infectious hepatitis C virus particles. J Virol 2010 1.38
26 Mutagenic effect of ribavirin on hepatitis C nonstructural 5B quasispecies in vitro and during antiviral therapy. Gastroenterology 2006 1.37
27 Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy. Hepatology 2007 1.36
28 Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication. J Virol 2004 1.36
29 Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha. J Gen Virol 2003 1.29
30 Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency. J Virol 2011 1.28
31 The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A. PLoS Pathog 2013 1.28
32 Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection. Cell Host Microbe 2012 1.24
33 Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells. Gastroenterology 2005 1.24
34 A target on the move: innate and adaptive immune escape strategies of hepatitis C virus. Antiviral Res 2006 1.19
35 Structural and functional analysis of hepatitis C virus strain JFH1 polymerase. J Virol 2009 1.17
36 Hepatitis C virus replication cycle. J Hepatol 2010 1.15
37 A comprehensive structure-function comparison of hepatitis C virus strain JFH1 and J6 polymerases reveals a key residue stimulating replication in cell culture across genotypes. J Virol 2011 1.07
38 Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle. PLoS Pathog 2013 1.02
39 Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo. Gastroenterology 2012 0.96
40 Human leukocyte antigen B27 selects for rare escape mutations that significantly impair hepatitis C virus replication and require compensatory mutations. Hepatology 2011 0.91
41 Bile acids specifically increase hepatitis C virus RNA-replication. PLoS One 2012 0.90
42 Experimental models to study the immunobiology of hepatitis C virus. J Gen Virol 2010 0.90
43 Annexin A2 as a differential diagnostic marker of hepatocellular tumors. Pathol Res Pract 2010 0.89
44 Relationships between hepatitis C virus replication and CXCL-8 production in vitro. J Virol 2006 0.89
45 Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential. J Hepatol 2012 0.86
46 Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B. Hepatology 2013 0.86
47 Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope. PLoS Pathog 2012 0.85
48 Differing and isoform-specific roles for the formin DIAPH3 in plasma membrane blebbing and filopodia formation. Cell Res 2011 0.82
49 TCR-redirected human T cells inhibit hepatitis C virus replication: hepatotoxic potential is linked to antigen specificity and functional avidity. J Immunol 2012 0.82
50 Nonstructural protein 5A does not contribute to the resistance of hepatitis C virus replication to interferon alpha in cell culture. Virology 2005 0.81
51 An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection. PLoS One 2011 0.80
52 The accelerating pace of HCV research: a summary of the 15th International Symposium on Hepatitis C Virus And Related Viruses. Gastroenterology 2008 0.79
53 In vitro replicative properties of replicons constructed using sequence variants of the hepatitis C virus strain AD78 that caused a single-source outbreak of hepatitis C. Virus Res 2009 0.77
54 Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3. J Gen Virol 2011 0.77
55 Hepatitis C virus replicons volume 3 and 4. Gastroenterology 2012 0.75
56 Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture. Nat Microbiol 2017 0.75