FGFR2 and other loci identified in genome-wide association studies are associated with breast cancer in African-American and younger women.

Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe Study. Cancer Epidemiol Biomarkers Prev (2011) 1.41

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1. Am J Hum Genet (2013) 1.39

Evaluation of 19 susceptibility loci of breast cancer in women of African ancestry. Carcinogenesis (2012) 1.38

A bayesian method for evaluating and discovering disease loci associations. PLoS One (2011) 1.19

Association of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer Study. Cancer Causes Control (2013) 1.13

Evaluating genome-wide association study-identified breast cancer risk variants in African-American women. PLoS One (2013) 1.10

Interactions among genes, tumor biology and the environment in cancer health disparities: examining the evidence on a national and global scale. Carcinogenesis (2011) 1.10

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age. Cancer Epidemiol Biomarkers Prev (2014) 1.03

Genome-Wide Association Studies (GWAS) breast cancer susceptibility loci in Arabs: susceptibility and prognostic implications in Tunisians. Breast Cancer Res Treat (2012) 1.01

Confounding and heterogeneity in genetic association studies with admixed populations. Am J Epidemiol (2013) 1.00

Replication of five GWAS-identified loci and breast cancer risk among Hispanic and non-Hispanic white women living in the Southwestern United States. Breast Cancer Res Treat (2011) 0.98

Joint effects of alcohol consumption and polymorphisms in alcohol and oxidative stress metabolism genes on risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev (2011) 0.95

Common genetic variation in adiponectin, leptin, and leptin receptor and association with breast cancer subtypes. Breast Cancer Res Treat (2011) 0.95

Fine mapping of breast cancer genome-wide association studies loci in women of African ancestry identifies novel susceptibility markers. Carcinogenesis (2013) 0.95

Associations with growth factor genes (FGF1, FGF2, PDGFB, FGFR2, NRG2, EGF, ERBB2) with breast cancer risk and survival: the Breast Cancer Health Disparities Study. Breast Cancer Res Treat (2013) 0.93

An integrative genomics approach to biomarker discovery in breast cancer. Cancer Inform (2011) 0.86

Decision tree-based modeling of androgen pathway genes and prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2011) 0.86

Replication of breast cancer susceptibility loci in whites and African Americans using a Bayesian approach. Am J Epidemiol (2013) 0.84

Polymorphisms in inflammatory genes are associated with term small for gestational age and preeclampsia. Am J Reprod Immunol (2014) 0.84

Replication of GWAS "Hits" by Race for Breast and Prostate Cancers in European Americans and African Americans. Front Genet (2011) 0.83

Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study. Cancer Epidemiol Biomarkers Prev (2015) 0.82

Contribution of toll-like receptor signaling pathways to breast tumorigenesis and treatment. Breast Cancer (Dove Med Press) (2013) 0.81

The use of the Gail model, body mass index and SNPs to predict breast cancer among women with abnormal (BI-RADS 4) mammograms. Breast Cancer Res (2015) 0.81

Quantitative assessment of 2q35-rs13387042 polymorphism and hormone receptor status with breast cancer risk. PLoS One (2013) 0.81

Single-nucleotide polymorphisms in nucleotide excision repair genes, cigarette smoking, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev (2013) 0.81

Association of polymorphisms in natural killer cell-related genes with preterm birth. Am J Epidemiol (2013) 0.80

Geographic differences in the distribution of molecular subtypes of breast cancer in Brazil. BMC Womens Health (2014) 0.80

Single nucleotide polymorphisms in nucleotide excision repair genes, cancer treatment, and head and neck cancer survival. Cancer Causes Control (2014) 0.80

A study on genetic variants of Fibroblast growth factor receptor 2 (FGFR2) and the risk of breast cancer from North India. PLoS One (2014) 0.80

Case-control study on the fibroblast growth factor receptor 2 gene polymorphisms associated with breast cancer in chinese han women. J Breast Cancer (2013) 0.79

Quantitative assessment of common genetic variants on chromosome 5p12 and hormone receptor status with breast cancer risk. PLoS One (2013) 0.79

Quantitative assessment of polymorphisms in H19 lncRNA and cancer risk: a meta-analysis of 13,392 cases and 18,893 controls. Oncotarget (2016) 0.79

IRAK4 and TLR3 Sequence Variants may Alter Breast Cancer Risk among African-American Women. Front Immunol (2013) 0.78

Associations between breast density and a panel of single nucleotide polymorphisms linked to breast cancer risk: a cohort study with digital mammography. BMC Cancer (2015) 0.78

Association of three SNPs in TOX3 and breast cancer risk: Evidence from 97275 cases and 128686 controls. Sci Rep (2015) 0.78

FGFR2 risk SNPs confer breast cancer risk by augmenting oestrogen responsiveness. Carcinogenesis (2016) 0.78

Effects of polymorphisms in alcohol metabolism and oxidative stress genes on survival from head and neck cancer. Cancer Epidemiol (2013) 0.77

Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortium. Breast Cancer Res Treat (2016) 0.77

Association between mitogen-activated protein kinase kinase kinase 1 polymorphisms and breast cancer susceptibility: a meta-analysis of 20 case-control studies. PLoS One (2014) 0.77

Assessing interactions between common genetic variant on 2q35 and hormone receptor status with breast cancer risk: evidence based on 26 studies. PLoS One (2013) 0.77

Diet and lifestyle factors modify immune/inflammation response genes to alter breast cancer risk and prognosis: the Breast Cancer Health Disparities Study. Mutat Res (2014) 0.77

Genetic variation in cell cycle regulatory gene AURKA and association with intrinsic breast cancer subtype. Mol Carcinog (2014) 0.76

Incremental impact of breast cancer SNP panel on risk classification in a screening population of white and African American women. Breast Cancer Res Treat (2013) 0.76

An exome-wide analysis of low frequency and rare variants in relation to risk of breast cancer in African American Women: the AMBER Consortium. Carcinogenesis (2016) 0.75

Association between 8q24 (rs13281615 and rs6983267) polymorphism and breast cancer susceptibility: a meta-analysis involving 117,355 subjects. Oncotarget (2016) 0.75

Toll-like receptor 4 as a predictor of clinical outcomes of estrogen receptor-negative breast cancer in Saudi women. Onco Targets Ther (2017) 0.75

Genetic Ancestry, Skin Reflectance and Pigmentation Genotypes in Association with Serum Vitamin D Metabolite Balance. Horm Mol Biol Clin Investig (2011) 0.75

The LSP1 rs3817198 T > C polymorphism contributes to increased breast cancer risk: a meta-analysis of twelve studies. Oncotarget (2016) 0.75

Polymorphisms in the carcinogen detoxification genes CYB5A and CYB5R3 and breast cancer risk in African American women. Cancer Causes Control (2014) 0.75

Significant association between lncRNA H19 polymorphisms and cancer susceptibility: a meta-analysis. Oncotarget (2017) 0.75

PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet (2007) 209.92

Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96

Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet (2007) 10.81

Genomewide association studies and human disease. N Engl J Med (2009) 9.05

Fibroblast growth factor signalling: from development to cancer. Nat Rev Cancer (2010) 8.55

Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat Genet (2009) 8.44

A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39

Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30

Evaluating associations of haplotypes with traits. Genet Epidemiol (2004) 5.70

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A (2008) 4.76

A genomewide single-nucleotide-polymorphism panel with high ancestry information for African American admixture mapping. Am J Hum Genet (2006) 3.77

Allele-specific up-regulation of FGFR2 increases susceptibility to breast cancer. PLoS Biol (2008) 3.49

Genetic predisposition to breast cancer: past, present, and future. Annu Rev Genomics Hum Genet (2008) 3.40

FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation. Hum Mol Genet (2009) 2.62

The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology. Breast Cancer Res Treat (1995) 2.31

Randomized recruitment in case-control studies. Am J Epidemiol (1991) 2.19

Hormone-dependent effects of FGFR2 and MAP3K1 in breast cancer susceptibility in a population-based sample of post-menopausal African-American and European-American women. Carcinogenesis (2008) 2.03

Evaluation of 11 breast cancer susceptibility loci in African-American women. Cancer Epidemiol Biomarkers Prev (2009) 1.90

Information on ancestry from genetic markers. Genet Epidemiol (2004) 1.72

Ancestry estimation and correction for population stratification in molecular epidemiologic association studies. Cancer Epidemiol Biomarkers Prev (2008) 1.43

Cigarette smoking, N-acetyltransferases 1 and 2, and breast cancer risk. Cancer Epidemiol Biomarkers Prev (1998) 1.43

Examining population stratification via individual ancestry estimates versus self-reported race. Cancer Epidemiol Biomarkers Prev (2005) 1.33

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev (2009) 1.29

Common genetic variants for breast cancer: 32 largely refuted candidates and larger prospects. J Natl Cancer Inst (2006) 0.97

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA (2006) 24.01

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy. Cancer Discov (2011) 7.65

A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37

Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res (2005) 3.26

The landscape of recombination in African Americans. Nature (2011) 3.06

Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study. Clin Cancer Res (2010) 3.04

Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nat Genet (2011) 3.02

Interleukin-6 as a therapeutic target in human ovarian cancer. Clin Cancer Res (2011) 2.85

A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11. Hum Mol Genet (2012) 2.45

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses. Cancer Res (2012) 2.24

Association of surgery with improved survival in stage IV breast cancer patients. Ann Surg (2008) 2.14

Identification of a basal-like subtype of breast ductal carcinoma in situ. Hum Pathol (2007) 2.12

Lifetime risk of melanoma in CDKN2A mutation carriers in a population-based sample. J Natl Cancer Inst (2005) 2.10

Comprehensive association study of type 2 diabetes and related quantitative traits with 222 candidate genes. Diabetes (2008) 2.01

Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer. Breast Cancer Res (2008) 2.01

Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry. Nat Genet (2013) 1.82

Comparative analysis of breast cancer risk factors among African-American women and White women. Am J Epidemiol (2005) 1.81

Prognostic significance of stromal platelet-derived growth factor beta-receptor expression in human breast cancer. Am J Pathol (2009) 1.81

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma. Cancer Res (2006) 1.80

A design for cancer case-control studies using only incident cases: experience with the GEM study of melanoma. Int J Epidemiol (2006) 1.80

Number of nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma. Cancer Epidemiol Biomarkers Prev (2007) 1.76

A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet (2011) 1.68

Obesity and screening for breast, cervical, and colorectal cancer in women: a review. Cancer (2008) 1.67

Physical activity and postmenopausal breast cancer: proposed biologic mechanisms and areas for future research. Cancer Epidemiol Biomarkers Prev (2009) 1.67

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons. Nat Neurosci (2013) 1.63

Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neurons. J Neurosci (2009) 1.62

High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype. Mod Pathol (2005) 1.57

A dynamic inflammatory cytokine network in the human ovarian cancer microenvironment. Cancer Res (2011) 1.55

Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes. Cancer (2010) 1.52

The prevalence of CDKN2A germ-line mutations and relative risk for cutaneous malignant melanoma: an international population-based study. Cancer Epidemiol Biomarkers Prev (2006) 1.51

Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer. J Transl Med (2010) 1.51

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry. PLoS Genet (2011) 1.47

Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African Americans. Hum Mol Genet (2011) 1.45

Ambient UV, personal sun exposure and risk of multiple primary melanomas. Cancer Causes Control (2007) 1.44

Polymorphisms in nucleotide excision repair genes, smoking and breast cancer in African Americans and whites: a population-based case-control study. Carcinogenesis (2006) 1.42

Survivin: a promising tumor biomarker. Cancer Lett (2007) 1.41

Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma. Cancer (2004) 1.40

FAK overexpression and p53 mutations are highly correlated in human breast cancer. Int J Cancer (2009) 1.35

CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance. Clin Cancer Res (2006) 1.35

Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer. Mod Pathol (2009) 1.34

Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer. Clin Cancer Res (2008) 1.34

A nomogram for individualized estimation of survival among patients with brain metastasis. Neuro Oncol (2012) 1.32

Increased claudin-4 expression is associated with poor prognosis and high tumour grade in breast cancer. Int J Cancer (2009) 1.30

Reproductive factors and breast cancer risk among older women. Breast Cancer Res Treat (2006) 1.30

SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas. Am J Surg Pathol (2011) 1.27

Proteome of synaptosome-associated proteins in spinal cord dorsal horn after peripheral nerve injury. Proteomics (2009) 1.27

Early onset prostate cancer has a significant genetic component. Prostate (2011) 1.26

Genome-wide association of body fat distribution in African ancestry populations suggests new loci. PLoS Genet (2013) 1.24

Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain. Mol Pain (2008) 1.24

Environmental risk factors in endemic pemphigus foliaceus (fogo selvagem). J Investig Dermatol Symp Proc (2004) 1.19

CENP-F expression is associated with poor prognosis and chromosomal instability in patients with primary breast cancer. Int J Cancer (2007) 1.17

SOX11 expression correlates to promoter methylation and regulates tumor growth in hematopoietic malignancies. Mol Cancer (2010) 1.16

Constipation, laxative use, and colon cancer in a North Carolina population. Am J Gastroenterol (2003) 1.16

RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer. Transl Oncol (2011) 1.16

CDKN2A germline mutations in individuals with cutaneous malignant melanoma. J Invest Dermatol (2007) 1.14

The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study. Breast Cancer Res (2005) 1.14

Association of germline microRNA SNPs in pre-miRNA flanking region and breast cancer risk and survival: the Carolina Breast Cancer Study. Cancer Causes Control (2013) 1.13

JAM-A expression positively correlates with poor prognosis in breast cancer patients. Int J Cancer (2009) 1.13

XRCC1 genotype and breast cancer: functional studies and epidemiologic data show interactions between XRCC1 codon 280 His and smoking. Cancer Res (2006) 1.12

A genome-wide association study of breast cancer in women of African ancestry. Hum Genet (2012) 1.11

Tandem BRAF mutations in primary invasive melanomas. J Invest Dermatol (2004) 1.10

High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer. Proteomics Clin Appl (2011) 1.10

Prognostic impact of tumour-specific HMG-CoA reductase expression in primary breast cancer. Breast Cancer Res (2008) 1.08

Trends in stage-specific incidence rates for urothelial carcinoma of the bladder in the United States: 1988 to 2006. Cancer (2013) 1.07

Glutathione-S-transferase genotypes, smoking, and their association with markers of inflammation, hemostasis, and endothelial function: the atherosclerosis risk in communities (ARIC) study. Atherosclerosis (2003) 1.06

Dynamic temporal and spatial regulation of mu opioid receptor expression in primary afferent neurons following spinal nerve injury. Eur J Pain (2011) 1.06

Consumption of trans-fatty acid and its association with colorectal adenomas. Am J Epidemiol (2008) 1.06

5,10-methylenetetrahydrofolate reductase 677 and 1298 polymorphisms, folate intake, and microsatellite instability in colon cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.05

UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans. Mutat Res (2008) 1.05

miR-187 is an independent prognostic factor in breast cancer and confers increased invasive potential in vitro. Clin Cancer Res (2012) 1.04

Population-specific coding variant underlies genome-wide association with adiponectin level. Hum Mol Genet (2011) 1.04

Association between non-steroidal anti-inflammatory drugs (NSAIDs) and invasive breast cancer and carcinoma in situ of the breast. Cancer Causes Control (2003) 1.04

Vitamin D receptor polymorphisms in patients with cutaneous melanoma. Int J Cancer (2011) 1.04

A critical assessment of transcranial doppler screening rates in a large pediatric sickle cell center: opportunities to improve healthcare quality. Pediatr Blood Cancer (2008) 1.04

Joint effects between UDP-glucuronosyltransferase 1A7 genotype and dietary carcinogen exposure on risk of colon cancer. Cancer Epidemiol Biomarkers Prev (2005) 1.04

Genetic studies in familial ankylosing spondylitis susceptibility. Arthritis Rheum (2004) 1.03

μ-Opioid receptor gene A118G polymorphism predicts survival in patients with breast cancer. Anesthesiology (2012) 1.03

Familial aggregation of melanoma risks in a large population-based sample of melanoma cases. Cancer Causes Control (2004) 1.03

Distance to diagnosing provider as a measure of access for patients with melanoma. Arch Dermatol (2007) 1.02

Patient perspectives on research recruitment through cancer registries. Cancer Causes Control (2005) 1.02

Polychlorinated biphenyls, cytochrome P450 1A1 (CYP1A1) polymorphisms, and breast cancer risk among African American women and white women in North Carolina: a population-based case-control study. Breast Cancer Res (2004) 1.02

COX-2 polymorphism, use of nonsteroidal anti-inflammatory drugs, and risk of colon cancer in African Americans (United States). Cancer Causes Control (2006) 1.01

Urbanization and breast cancer incidence in North Carolina, 1995-1999. Ann Epidemiol (2005) 1.01

The tumor suppressor CDKN3 controls mitosis. J Cell Biol (2013) 1.01

A locus on chromosome 9p predisposes to a specific disease manifestation, acute anterior uveitis, in ankylosing spondylitis, a genetically complex, multisystem, inflammatory disease. Arthritis Rheum (2005) 1.00

Birthweight, parental age, birth order and breast cancer risk in African-American and white women: a population-based case-control study. Breast Cancer Res (2004) 1.00

Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer. BMC Cancer (2013) 0.99

Increased androgen receptor expression in serous carcinoma of the ovary is associated with an improved survival. J Ovarian Res (2010) 0.98

DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival. Breast Cancer Res (2014) 0.98

ADIPOQ, ADIPOR1, and ADIPOR2 polymorphisms in relation to serum adiponectin levels and BMI in black and white women. Obesity (Silver Spring) (2011) 0.98

Evaluation of the prognostic significance of MSMB and CRISP3 in prostate cancer using automated image analysis. Mod Pathol (2011) 0.97

Determinants of breast cancer treatment delay differ for African American and White women. Cancer Epidemiol Biomarkers Prev (2013) 0.97

Family history of colon cancer: what does it mean and how is it useful? Am J Prev Med (2003) 0.96

Methylation of HIN-1, RASSF1A, RIL and CDH13 in breast cancer is associated with clinical characteristics, but only RASSF1A methylation is associated with outcome. BMC Cancer (2012) 0.96