Jan Kajstura

Author PubWeight™ 197.44‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 2003 18.09
2 Concern Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet 2011 11.45
3 Chimerism of the transplanted heart. N Engl J Med 2002 8.69
4 Human cardiac stem cells. Proc Natl Acad Sci U S A 2007 7.76
5 Stem cell niches in the adult mouse heart. Proc Natl Acad Sci U S A 2006 4.58
6 Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression. Circ Res 2004 4.13
7 Stem cells in the dog heart are self-renewing, clonogenic, and multipotent and regenerate infarcted myocardium, improving cardiac function. Proc Natl Acad Sci U S A 2005 4.13
8 Cardiac stem cells possess growth factor-receptor systems that after activation regenerate the infarcted myocardium, improving ventricular function and long-term survival. Circ Res 2005 3.93
9 Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. Proc Natl Acad Sci U S A 2005 3.93
10 Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function. Proc Natl Acad Sci U S A 2005 3.64
11 Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction. Circulation 2010 3.42
12 Cardiac stem cells and mechanisms of myocardial regeneration. Physiol Rev 2005 3.30
13 Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function. Circ Res 2008 3.07
14 Bone marrow cells adopt the cardiomyogenic fate in vivo. Proc Natl Acad Sci U S A 2007 3.06
15 Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy. Proc Natl Acad Sci U S A 2003 2.95
16 Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ Res 2004 2.91
17 Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance. Circulation 2012 2.83
18 Role of cardiac stem cells in cardiac pathophysiology: a paradigm shift in human myocardial biology. Circ Res 2011 2.76
19 Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66shc gene. Circ Res 2006 2.71
20 Clonality of mouse and human cardiomyogenesis in vivo. Proc Natl Acad Sci U S A 2009 2.60
21 Life and death of cardiac stem cells: a paradigm shift in cardiac biology. Circulation 2006 2.56
22 Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure. Circ Res 2003 2.45
23 Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med 2007 2.39
24 Human cardiac stem cell differentiation is regulated by a mircrine mechanism. Circulation 2011 2.38
25 Adolescent feline heart contains a population of small, proliferative ventricular myocytes with immature physiological properties. Circ Res 2007 2.38
26 Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population. Circ Res 2006 2.34
27 Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ Res 2005 2.32
28 Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res 2008 2.31
29 Cardiac progenitor cells and biotinylated insulin-like growth factor-1 nanofibers improve endogenous and exogenous myocardial regeneration after infarction. Circulation 2009 2.30
30 Recombinant human erythropoietin protects the myocardium from ischemia-reperfusion injury and promotes beneficial remodeling. Proc Natl Acad Sci U S A 2003 2.28
31 Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ Res 2003 2.26
32 Identification of a coronary vascular progenitor cell in the human heart. Proc Natl Acad Sci U S A 2009 2.23
33 Notch1 regulates the fate of cardiac progenitor cells. Proc Natl Acad Sci U S A 2008 2.22
34 Cardiac-specific IGF-1 expression attenuates dilated cardiomyopathy in tropomodulin-overexpressing transgenic mice. Circ Res 2002 2.11
35 Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci U S A 2008 2.05
36 Functionally competent cardiac stem cells can be isolated from endomyocardial biopsies of patients with advanced cardiomyopathies. Circ Res 2011 1.98
37 Postinfarct cytokine therapy regenerates cardiac tissue and improves left ventricular function. Circ Res 2006 1.98
38 Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge. Circ Res 2008 1.97
39 Regenerating new heart with stem cells. J Clin Invest 2013 1.83
40 Insulin-like growth factor-1 receptor identifies a pool of human cardiac stem cells with superior therapeutic potential for myocardial regeneration. Circ Res 2011 1.77
41 Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes. Circulation 2013 1.73
42 The young mouse heart is composed of myocytes heterogeneous in age and function. Circ Res 2007 1.69
43 Cardiac regeneration. J Am Coll Cardiol 2006 1.67
44 Bone marrow stem cells regenerate infarcted myocardium. Pediatr Transplant 2003 1.66
45 Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. EMBO J 2003 1.66
46 Anthracycline cardiomyopathy is mediated by depletion of the cardiac stem cell pool and is rescued by restoration of progenitor cell function. Circulation 2009 1.62
47 Age-associated defects in EphA2 signaling impair the migration of human cardiac progenitor cells. Circulation 2013 1.61
48 Effects of age and heart failure on human cardiac stem cell function. Am J Pathol 2011 1.57
49 Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy. Circulation 2013 1.53
50 Nuclear targeting of Akt antagonizes aspects of cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A 2006 1.48
51 Cardiomyogenesis in the developing heart is regulated by c-kit-positive cardiac stem cells. Circ Res 2012 1.37
52 Concise review: stem cells, myocardial regeneration, and methodological artifacts. Stem Cells 2006 1.34
53 Spontaneous calcium oscillations regulate human cardiac progenitor cell growth. Circ Res 2009 1.32
54 Pim-1 kinase antagonizes aspects of myocardial hypertrophy and compensation to pathological pressure overload. Proc Natl Acad Sci U S A 2008 1.31
55 Cardiac-specific overexpression of insulin-like growth factor 1 attenuates aging-associated cardiac diastolic contractile dysfunction and protein damage. Am J Physiol Heart Circ Physiol 2006 1.23
56 bcl-2 overexpression promotes myocyte proliferation. Proc Natl Acad Sci U S A 2002 1.22
57 Myocardial aging--a stem cell problem. Basic Res Cardiol 2005 1.17
58 c-Kit-positive cardiac stem cells nested in hypoxic niches are activated by stem cell factor reversing the aging myopathy. Circ Res 2013 1.15
59 The ephrin A1-EphA2 system promotes cardiac stem cell migration after infarction. Circ Res 2011 1.14
60 IGF-I alleviates diabetes-induced RhoA activation, eNOS uncoupling, and myocardial dysfunction. Am J Physiol Regul Integr Comp Physiol 2008 1.11
61 Myocardial regeneration and stem cell repair. Curr Probl Cardiol 2008 1.08
62 Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart. Circ Res 2009 1.06
63 Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart. Circ Res 2010 1.06
64 Myocyte growth and cardiac repair. J Mol Cell Cardiol 2002 1.01
65 If I can stop one heart from breaking. Circulation 2007 0.99
66 Increasing cardiac contractility after myocardial infarction exacerbates cardiac injury and pump dysfunction. Circ Res 2010 0.97
67 Tissue-specific adult stem cells in the human lung. Nat Med 2011 0.97
68 A matter of life and death: cardiac myocyte apoptosis and regeneration. J Clin Invest 2003 0.97
69 Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation 2008 0.96
70 Mitotically inactivated embryonic stem cells can be used as an in vivo feeder layer to nurse damaged myocardium after acute myocardial infarction: a preclinical study. Circ Res 2012 0.95
71 Mechanisms of myocardial regeneration. Circ J 2009 0.95
72 Regeneration of the infarcted heart with stem cells derived by nuclear transplantation. Circ Res 2004 0.94
73 Priming with ligands secreted by human stromal progenitor cells promotes grafts of cardiac stem/progenitor cells after myocardial infarction. Stem Cells 2014 0.92
74 Metalloproteinase inhibitor counters high-energy phosphate depletion and AMP deaminase activity enhancing ventricular diastolic compliance in subacute heart failure. J Pharmacol Exp Ther 2006 0.89
75 Effect of cardiac stem cells on left-ventricular remodeling in a canine model of chronic myocardial infarction. Circ Heart Fail 2012 0.88
76 Some like it plastic. Circ Res 2004 0.88
77 Myocardial Regeneration by Exogenous and Endogenous Progenitor Cells. Drug Discov Today Dis Mech 2007 0.84
78 Endothelial progenitor cells: neovascularization or more? J Mol Cell Cardiol 2006 0.84
79 Mechanisms of myocardial regeneration. Trends Cardiovasc Med 2011 0.83
80 Myocyte proliferation and ventricular remodeling. J Card Fail 2002 0.82
81 Biased DNA segregation during stem cell division. Circ Res 2012 0.82
82 The existence of myocardial repair: mechanistic insights and enhancements. Cardiol Rev 2013 0.82
83 Identification of a coronary stem cell in the human heart. J Mol Med (Berl) 2011 0.81
84 Cardiac stem cells and myocardial regeneration. Novartis Found Symp 2005 0.81
85 Primitive cells and tissue regeneration. Circ Res 2003 0.80
86 Myocardial damage and repair. J Mol Cell Cardiol 2003 0.80
87 Identity deception: not a crime for a stem cell. Physiology (Bethesda) 2005 0.79
88 Regenerating the myocardium: a reality today. Can J Cardiol 2005 0.79
89 Circulating progenitor cells: search for an identity. Circulation 2004 0.78
90 Endothelial progenitor cells: unexpected disclosures. Circ Res 2005 0.77
91 Created equal? The many facets of cell reprogramming. Circ Res 2012 0.76
92 [Bone marrow cells and cardiac repair]. Arq Bras Cardiol 2006 0.75
93 Adeno-associated virus mediated gene delivery into coronary microvessels of chronically instrumented dogs. J Appl Physiol (1985) 2003 0.75
94 Heart failure and regenerative cardiology. Regen Med 2006 0.75