Large-scale expression analysis reveals distinct microRNA profiles at different stages of human neurodevelopment.

PubWeight™: 1.10‹?› | Rank: Top 10%

🔗 View Article (PMC 2886071)

Published in PLoS One on June 15, 2010

Authors

Brandon Smith1, Julie Treadwell, Dongling Zhang, Dao Ly, Iain McKinnell, P Roy Walker, Marianna Sikorska

Author Affiliations

1: Institute for Biological Sciences, National Research Council Canada, Ottawa, Canada. brandon.smith@nrc-cnrc.gc.ca

Articles citing this

Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes Dev (2011) 1.55

SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase. J Cell Biol (2011) 1.29

The emerging roles of microRNAs in CNS injuries. Nat Rev Neurol (2013) 1.18

MicroRNA in central nervous system trauma and degenerative disorders. Physiol Genomics (2011) 1.10

MicroRNAs in vitreus humor from patients with ocular diseases. Mol Vis (2013) 1.00

The role of microRNAs in human neural stem cells, neuronal differentiation and subtype specification. Cell Tissue Res (2014) 0.98

MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist Kremen1. Front Mol Neurosci (2013) 0.98

Profiling of REST-Dependent microRNAs Reveals Dynamic Modes of Expression. Front Neurosci (2012) 0.92

Role of miRNAs in neuronal differentiation from human embryonic stem cell-derived neural stem cells. Stem Cell Rev (2012) 0.91

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation. Oncotarget (2014) 0.91

MicroRNA dysregulation in spinal cord injury: causes, consequences and therapeutics. Front Cell Neurosci (2014) 0.91

The effects of microRNAs on human neural stem cell differentiation in two- and three-dimensional cultures. Stem Cell Res Ther (2014) 0.89

Molecular mechanisms of peripheral nerve regeneration: emerging roles of microRNAs. Front Physiol (2013) 0.86

Down-regulation of RE-1 silencing transcription factor (REST) in advanced prostate cancer by hypoxia-induced miR-106b~25. Exp Cell Res (2013) 0.86

Rapid differentiation of human embryonal carcinoma stem cells (NT2) into neurons for neurite outgrowth analysis. Cell Mol Neurobiol (2011) 0.86

Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96. Eur J Neurosci (2013) 0.82

Specification of neural cell fate and regulation of neural stem cell proliferation by microRNAs. Am J Stem Cells (2012) 0.82

Schwann cell-free adult canine olfactory ensheathing cell preparations from olfactory bulb and mucosa display differential migratory and neurite growth-promoting properties in vitro. BMC Neurosci (2013) 0.81

General hallmarks of microRNAs in brain evolution and development. RNA Biol (2015) 0.81

p38α controls self-renewal and fate decision of neurosphere-forming cells in adult hippocampus. FEBS Open Bio (2015) 0.79

Epigenetic programming of hypoxic-ischemic encephalopathy in response to fetal hypoxia. Prog Neurobiol (2014) 0.79

Ontogeny of small RNA in the regulation of mammalian brain development. BMC Genomics (2014) 0.79

A positive feedback mechanism that regulates expression of miR-9 during neurogenesis. PLoS One (2014) 0.79

Differential methylation of the micro-RNA 7b gene targets postnatal maturation of murine neuronal Mecp2 gene expression. Dev Neurobiol (2013) 0.78

The Transcriptional Response of Neurotrophins and Their Tyrosine Kinase Receptors in Lumbar Sensorimotor Circuits to Spinal Cord Contusion is Affected by Injury Severity and Survival Time. Front Physiol (2013) 0.78

MicroRNAs as potential therapeutics for treating spinal cord injury. Neural Regen Res (2012) 0.78

MicroRNA-181 promotes synaptogenesis and attenuates axonal outgrowth in cortical neurons. Cell Mol Life Sci (2016) 0.77

MicroRNAs 29b and 181a down-regulate the expression of the norepinephrine transporter and glucocorticoid receptors in PC12 cells. J Neurochem (2016) 0.76

microRNAs and the adolescent brain: Filling the knowledge gap. Neurosci Biobehav Rev (2016) 0.75

Identification of β-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation. PLoS One (2016) 0.75

Differentiation impairs Bach1 dependent HO-1 activation and increases sensitivity to oxidative stress in SH-SY5Y neuroblastoma cells. Sci Rep (2017) 0.75

Articles cited by this

The human genome browser at UCSC. Genome Res (2002) 168.23

Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A (2001) 132.88

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87

Genome-wide mapping of in vivo protein-DNA interactions. Science (2007) 64.92

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature (2005) 48.95

An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science (2001) 44.16

miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res (2006) 39.25

miRBase: tools for microRNA genomics. Nucleic Acids Res (2007) 38.61

Identification of tissue-specific microRNAs from mouse. Curr Biol (2002) 34.55

Human MicroRNA targets. PLoS Biol (2004) 34.51

An extensive class of small RNAs in Caenorhabditis elegans. Science (2001) 34.17

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60

Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15

Embryonic stem cell-specific MicroRNAs. Dev Cell (2003) 13.05

MicroRNAs regulate brain morphogenesis in zebrafish. Science (2005) 11.16

Computational identification of Drosophila microRNA genes. Genome Biol (2003) 9.86

A microRNA array reveals extensive regulation of microRNAs during brain development. RNA (2003) 9.76

A custom microarray platform for analysis of microRNA gene expression. Nat Methods (2004) 9.44

Human embryonic stem cells express a unique set of microRNAs. Dev Biol (2004) 8.87

REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell (2005) 8.65

A MicroRNA feedback circuit in midbrain dopamine neurons. Science (2007) 8.33

Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science (2005) 8.20

The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell (2007) 7.99

Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol (2004) 7.33

The neuron-restrictive silencer factor (NRSF): a coordinate repressor of multiple neuron-specific genes. Science (1995) 6.85

Specific microRNAs modulate embryonic stem cell-derived neurogenesis. Stem Cells (2005) 6.72

REST: a mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell (1995) 6.43

An abundance of bidirectional promoters in the human genome. Genome Res (2004) 5.90

Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci U S A (2006) 5.78

Regulation of miRNA expression during neural cell specification. Eur J Neurosci (2005) 5.27

miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. Nat Neurosci (2009) 5.27

Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc Natl Acad Sci U S A (2008) 5.24

The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. Genes Dev (2007) 5.16

The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci (2008) 4.28

Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev Biol (1984) 4.16

Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol (2008) 4.07

MicroRNA fingerprints during human megakaryocytopoiesis. Proc Natl Acad Sci U S A (2006) 3.80

The bifunctional microRNA miR-9/miR-9* regulates REST and CoREST and is downregulated in Huntington's disease. J Neurosci (2008) 3.62

Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci U S A (2004) 3.39

A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci U S A (2007) 3.15

MicroRNA expression in the adult mouse central nervous system. RNA (2008) 3.12

REST maintains self-renewal and pluripotency of embryonic stem cells. Nature (2008) 3.06

MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth. Cell Res (2008) 2.90

Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A (2007) 2.60

A microRNA-based gene dysregulation pathway in Huntington's disease. Neurobiol Dis (2007) 2.41

The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene. Proc Natl Acad Sci U S A (2008) 2.09

NTera 2 cells: a human cell line which displays characteristics expected of a human committed neuronal progenitor cell. J Neurosci Res (1993) 1.97

Embryonic stem cell-specific miR302-367 cluster: human gene structure and functional characterization of its core promoter. Mol Cell Biol (2008) 1.74

Identification of the REST regulon reveals extensive transposable element-mediated binding site duplication. Nucleic Acids Res (2006) 1.62

Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene. Dev Biol (2006) 1.47

Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression. Mol Cell Biol (2000) 1.46

Nonrestrictive developmental regulation of microRNA gene expression. Mamm Genome (2006) 1.41

Identification of new central nervous system specific mouse microRNAs. FEBS Lett (2006) 1.40

Rational probe optimization and enhanced detection strategy for microRNAs using microarrays. RNA Biol (2005) 1.31

miRNAminer: a tool for homologous microRNA gene search. BMC Bioinformatics (2008) 1.21

Marked change in microRNA expression during neuronal differentiation of human teratocarcinoma NTera2D1 and mouse embryonal carcinoma P19 cells. Biochem Biophys Res Commun (2007) 1.13

Regulation of the mammalian nervous system by microRNAs. Mol Pharmacol (2008) 0.96

Human NT2/D1 cells differentiate into functional astrocytes. Neuroreport (1999) 0.92

MicroRNA expression profile in murine central nervous system development. J Mol Neurosci (2008) 0.92

Cytoskeleton of human embryonal carcinoma cells. Cell Differ (1984) 0.87

Developmental regulation of neurogenesis in the pluripotent human embryonal carcinoma cell line NTERA-2. Eur J Neurosci (2000) 0.86

MicroRNA expression profiling during neural differentiation of mouse embryonic carcinoma P19 cells. Acta Biochim Biophys Sin (Shanghai) (2009) 0.86

Genome-wide computational analyses of microRNAs and their targets from Canis familiaris. Comput Biol Chem (2007) 0.83

[Knockdown and overexpression of miR-219 lead to embryonic defects in zebrafish development]. Fen Zi Xi Bao Sheng Wu Xue Bao (2008) 0.80

Effects of glutathione depletion on the viability of human NT2-derived neuronal and astroglial cultures. Neuron Glia Biol (2004) 0.78

Articles by these authors

Role of Sox2 in the development of the mouse neocortex. Dev Biol (2006) 2.32

Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis. Dev Biol (2004) 2.12

Sequential DNA methylation of the Nanog and Oct-4 upstream regions in human NT2 cells during neuronal differentiation. J Biol Chem (2004) 1.94

Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells. FASEB J (2009) 1.62

A core collection and mini core collection of Oryza sativa L. in China. Theor Appl Genet (2010) 1.46

Myostatin imposes reversible quiescence on embryonic muscle precursors. Dev Dyn (2006) 1.24

Differentiation of mouse Neuro 2A cells into dopamine neurons. J Neurosci Methods (2009) 1.19

The regulation and action of myostatin as a negative regulator of muscle development during avian embryogenesis. Dev Biol (2002) 1.19

Epigenetic modifications of SOX2 enhancers, SRR1 and SRR2, correlate with in vitro neural differentiation. J Neurosci Res (2008) 1.09

Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity. Neurobiol Dis (2008) 1.02

Transcriptional activation of the human brain-derived neurotrophic factor gene promoter III by dopamine signaling in NT2/N neurons. J Biol Chem (2003) 1.01

Measurement of apoptosis by DNA fragmentation. Methods Mol Biol (2004) 1.01

Paraquat induces oxidative stress, neuronal loss in substantia nigra region and parkinsonism in adult rats: neuroprotection and amelioration of symptoms by water-soluble formulation of coenzyme Q10. BMC Neurosci (2009) 1.00

Probing stemness and neural commitment in human amniotic fluid cells. Stem Cell Rev (2010) 0.98

Characterization of astrocytes derived from human NTera-2/D1 embryonal carcinoma cells. J Neurosci Res (2002) 0.95

Wnt 6 regulates the epithelialisation process of the segmental plate mesoderm leading to somite formation. Dev Biol (2004) 0.93

Water-soluble formulation of Coenzyme Q10 inhibits Bax-induced destabilization of mitochondria in mammalian cells. Apoptosis (2006) 0.93

Chick PTPsigma regulates the targeting of retinal axons within the optic tectum. J Neurosci (2002) 0.92

Evolution of motif variants and positional bias of the cyclic-AMP response element. BMC Evol Biol (2007) 0.92

Neuroprotective effects of coenzyme Q10 at rostral ventrolateral medulla against fatality during experimental endotoxemia in the rat. Shock (2003) 0.89

Identification of functional dopamine receptors in human teratocarcinoma NT2 cells. Brain Res Mol Brain Res (2002) 0.89

A novel brain-enriched E3 ubiquitin ligase RNF182 is up regulated in the brains of Alzheimer's patients and targets ATP6V0C for degradation. Mol Neurodegener (2008) 0.89

Molecular mechanisms of glutamate neurotoxicity in mixed cultures of NT2-derived neurons and astrocytes: protective effects of coenzyme Q10. J Neurosci Res (2003) 0.88

Identification of blottin: a novel gastric trefoil factor family-2 binding protein. Proteomics (2006) 0.87

Regulation of MYPT1 stability by the E3 ubiquitin ligase SIAH2. Exp Cell Res (2009) 0.87

Albumin targeting of damaged muscle fibres in the mdx mouse can be monitored by MRI. Neuromuscul Disord (2004) 0.86

Attenuation of free radical production and paracrystalline inclusions by creatine supplementation in a patient with a novel cytochrome b mutation. Muscle Nerve (2004) 0.86

Analysis of behavior using genetical genomics in mice as a model: from alcohol preferences to gene expression differences. Genome (2007) 0.85

Neurogenesis and neuronal communication on micropatterned neurochips. Biotechnol Bioeng (2005) 0.84

Major components of the insulin-like growth factor axis are expressed early in chicken embryogenesis, with IGF binding protein ( IGFBP) -5 expression subject to regulation by Sonic Hedgehog. Anat Embryol (Berl) (2003) 0.83

Neuroregenerative strategies in the brain: emerging significance of bone morphogenetic protein 7 (BMP7). Biochem Cell Biol (2008) 0.83

Novel subtractive transcription-based amplification of mRNA (STAR) method and its application in search of rare and differentially expressed genes in AD brains. BMC Genomics (2006) 0.82

Unique technology for solubilization and delivery of highly lipophilic bioactive molecules. J Drug Target (2004) 0.81

Assessing indica-japonica differentiation of improved rice varieties using microsatellite markers. J Genet Genomics (2009) 0.80

Derivatised alpha-tocopherol as a CoQ10 carrier in a novel water-soluble formulation. Biofactors (2003) 0.80

Labeling DNA damage with terminal transferase. Applicability, specificity, and limitations. Methods Mol Biol (2002) 0.79

Orally delivered water soluble Coenzyme Q10 (Ubisol-Q10) blocks on-going neurodegeneration in rats exposed to paraquat: potential for therapeutic application in Parkinson's disease. BMC Neurosci (2014) 0.79

Novel RBPJ transcripts identified in human amniotic fluid cells. Stem Cell Rev (2010) 0.79

Involvement of NOS3 in RA-Induced neural differentiation of human NT2/D1 cells. J Neurosci Res (2012) 0.78

Effects of glutathione depletion on the viability of human NT2-derived neuronal and astroglial cultures. Neuron Glia Biol (2004) 0.78

Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation. Biochem J (2005) 0.78

Development of BMP7-producing human cells, using a third generation lentiviral gene delivery system. J Neurosci Methods (2011) 0.78

Attenuation of UV-induced apoptosis by coenzyme Q10 in human cells harboring large-scale deletion of mitochondrial DNA. Ann N Y Acad Sci (2005) 0.77

Induction of human immunodeficiency virus (HIV-1) envelope specific cell-mediated immunity by a non-homologous synthetic peptide. PLoS One (2007) 0.77

Neuroprotective effects of GDNF-expressing human amniotic fluid cells. Stem Cell Rev (2014) 0.77

Identification of a functional CRE in the promoter of Fukuyama congenital muscular dystrophy gene fukutin. Brain Res Mol Brain Res (2005) 0.77

Role of the fourth intracellular loop of D1-like dopaminergic receptors in conferring subtype-specific signaling properties. FEBS Lett (2004) 0.76

Human amniotic fluid cells form functional gap junctions with cortical cells. Stem Cells Int (2012) 0.76

Therapeutic potential of amniotic fluid-derived cells for treating the injured nervous system. Biochem Cell Biol (2013) 0.75