Published in Apoptosis on August 01, 2010
Identification of markers of prostate cancer progression using candidate gene expression. Br J Cancer (2011) 1.04
Conditional over-expression of PITX1 causes skeletal muscle dystrophy in mice. Biol Open (2012) 0.90
The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. Nucleic Acids Res (2013) 0.84
JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat Cell Biol (2005) 2.56
Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage. Cancer Sci (2004) 2.33
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol Cell (2007) 2.18
Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol Cell (2010) 2.09
DF3/MUC1 signaling in multiple myeloma cells is regulated by interleukin-7. Cancer Biol Ther (2003) 1.96
C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther (2002) 1.95
Regulation of a transient receptor potential (TRP) channel by tyrosine phosphorylation. SRC family kinase-dependent tyrosine phosphorylation of TRPV4 on TYR-253 mediates its response to hypotonic stress. J Biol Chem (2003) 1.50
Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage. J Biol Chem (2005) 1.50
Genetic and histological assessment of surgical margins in resected liver metastases from colorectal carcinoma: minimum surgical margins for successful resection. Arch Surg (2002) 1.49
Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome Res (2011) 1.47
Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J (2003) 1.47
Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor. Cancer Biol Ther (2003) 1.44
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage. EMBO J (2006) 1.42
Reduced levels of ATF-2 predispose mice to mammary tumors. Mol Cell Biol (2006) 1.22
Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis. Int J Oncol (2004) 1.20
DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells. J Clin Invest (2012) 1.18
Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage. J Biol Chem (2002) 1.11
The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha). J Biol Chem (2007) 1.09
Identification of novel deletion polymorphisms in breast cancer. Int J Oncol (2008) 1.08
Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. Mol Cell Biol (2007) 1.08
Transforming mutations of RAC guanosine triphosphatases in human cancers. Proc Natl Acad Sci U S A (2013) 1.07
Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest (2012) 1.02
ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage. J Biol Chem (2009) 1.02
Binding of IgG-opsonized particles to Fc gamma R is an active stage of phagocytosis that involves receptor clustering and phosphorylation. J Immunol (2005) 1.01
Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division. Biochem Biophys Res Commun (2007) 1.01
Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci (2007) 1.00
Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members. J Biol Chem (2001) 1.00
IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis. Clin Cancer Res (2008) 0.99
Identification and characterization of the human protein kinase-like gene NTKL: mitosis-specific centrosomal localization of an alternatively spliced isoform. Genomics (2002) 0.99
Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells. Am J Pathol (2009) 0.99
Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology (2011) 0.98
The cell death machinery governed by the p53 tumor suppressor in response to DNA damage. Cancer Sci (2010) 0.98
DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter. Biochem J (2009) 0.98
A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese. J Hum Genet (2012) 0.94
DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail. Cancer Lett (2013) 0.94
Protein kinase Cdelta activates RelA/p65 and nuclear factor-kappaB signaling in response to tumor necrosis factor-alpha. Cancer Res (2009) 0.93
Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer. Cancer Sci (2008) 0.93
Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress. Cell Signal (2007) 0.93
BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization. Cancer Sci (2009) 0.93
Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage. Mol Cell Biol (2006) 0.92
Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta. J Biol Chem (2003) 0.91
High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas. Breast Cancer Res Treat (2011) 0.90
A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress. Nucleic Acids Res (2008) 0.89
Expression of basal cell keratin 15 and keratin 19 in oral squamous neoplasms represents diverse pathophysiologies. Histol Histopathol (2012) 0.89
Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer. J Hum Genet (2007) 0.88
Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray. Cancer Sci (2004) 0.88
Genome-wide association study of breast cancer in the Japanese population. PLoS One (2013) 0.87
BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK2. Cancer Res (2010) 0.87
Tumor suppressor p53 induces miR-1915 processing to inhibit Bcl-2 in the apoptotic response to DNA damage. FEBS J (2014) 0.87
Conserved domains in the chicken homologue of BRCA2. Oncogene (2002) 0.87
Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome-wide expression profiling. Cancer Sci (2009) 0.87
Enabling death by the Abl tyrosine kinase: mechanisms for nuclear shuttling of c-Abl in response to DNA damage. Cell Cycle (2005) 0.87
Programmed cell death 6, a novel p53-responsive gene, targets to the nucleus in the apoptotic response to DNA damage. Cancer Sci (2012) 0.86
Identification of dihydropyrimidinase-related protein 4 as a novel target of the p53 tumor suppressor in the apoptotic response to DNA damage. Int J Cancer (2010) 0.86
Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer. Oncology (2005) 0.85
Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer. Breast Cancer (2008) 0.85
Induction of amphiregulin by p53 promotes apoptosis via control of microRNA biogenesis in response to DNA damage. Proc Natl Acad Sci U S A (2013) 0.85
Abnormal collagen deposition in fibromas from patient with juvenile hyaline fibromatosis. J Dermatol Sci (2009) 0.85
BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC. Cancer Res (2014) 0.85
A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumor-suppressor gene. Int J Clin Oncol (2008) 0.84
Prevalence and differentiation of hereditary breast and ovarian cancers in Japan. Breast Cancer (2013) 0.84
BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress. Antioxid Redox Signal (2008) 0.84
Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC. Int J Exp Pathol (2006) 0.83
Gene expression profiling of breast cancer. Breast Cancer (2006) 0.82
Mutation analysis of the mel-18 gene that shows decreased expression in human breast cancer cell lines. Breast Cancer (2002) 0.80
Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas. Surgery (2009) 0.80
DYRK2 regulates epithelial-mesenchymal-transition and chemosensitivity through Snail degradation in ovarian serous adenocarcinoma. Tumour Biol (2015) 0.79
Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis. Clin Cancer Res (2008) 0.79
Prognostic value of matrix Gla protein in breast cancer. Mol Med Rep (2011) 0.79
Histological features of breast cancer, highly sensitive to chemotherapy. Breast Cancer (2007) 0.79
Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers. J Cancer Res Clin Oncol (2004) 0.79
D4S234E, a novel p53-responsive gene, induces apoptosis in response to DNA damage. Exp Cell Res (2010) 0.79
Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage. Cancer Sci (2008) 0.79
Relatively common mutations of the Bloom syndrome gene in the Japanese population. Int J Mol Med (2004) 0.78
Frequency of immunohistochemical loss of mismatch repair protein in double primary cancers of the colorectum and stomach in Japan. Dis Colon Rectum (2006) 0.77
Postoperative prognosis of node-negative breast cancers predicted by gene-expression profiling on a cDNA microarray of 25,344 genes. Breast Cancer (2005) 0.77
Development of detection method for novel fusion gene using GeneChip exon array. J Clin Bioinforma (2014) 0.77
[Gene expression profiling for prediction of response to chemotherapy]. Gan To Kagaku Ryoho (2006) 0.77
Engagement of DYRK2 in proper control for cell division. Cell Cycle (2015) 0.77
Identification of Evi-1 as a novel effector of PKCδ in the apoptotic response to DNA damage. Biochim Biophys Acta (2011) 0.77
PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage. Mol Carcinog (2011) 0.77
Immunohistochemical study of β-catenin and functionally related molecular markers in tongue squamous cell carcinoma and its correlation with cellular proliferation. Oncol Lett (2010) 0.77
Common peak approach using mass spectrometry data sets for predicting the effects of anticancer drugs on breast cancer. Cancer Inform (2007) 0.75