Yoshio Miki

Author PubWeight™ 75.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 JNK phosphorylation of 14-3-3 proteins regulates nuclear targeting of c-Abl in the apoptotic response to DNA damage. Nat Cell Biol 2005 2.56
2 Role of BRCA1 and BRCA2 as regulators of DNA repair, transcription, and cell cycle in response to DNA damage. Cancer Sci 2004 2.33
3 DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage. Mol Cell 2007 2.18
4 Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Mol Cell 2010 2.09
5 C421A polymorphism in the human breast cancer resistance protein gene is associated with low expression of Q141K protein and low-level drug resistance. Mol Cancer Ther 2002 1.95
6 Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage. J Biol Chem 2005 1.50
7 Genetic and histological assessment of surgical margins in resected liver metastases from colorectal carcinoma: minimum surgical margins for successful resection. Arch Surg 2002 1.49
8 Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency. Genome Res 2011 1.47
9 Protein kinase Cdelta is responsible for constitutive and DNA damage-induced phosphorylation of Rad9. EMBO J 2003 1.47
10 Reduced levels of ATF-2 predispose mice to mammary tumors. Mol Cell Biol 2006 1.22
11 Genome-wide gene-expression profiles of breast-cancer cells purified with laser microbeam microdissection: identification of genes associated with progression and metastasis. Int J Oncol 2004 1.20
12 DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells. J Clin Invest 2012 1.18
13 Activation of SAPK/JNK signaling by protein kinase Cdelta in response to DNA damage. J Biol Chem 2002 1.11
14 The deubiquitinating enzyme USP11 controls an IkappaB kinase alpha (IKKalpha)-p53 signaling pathway in response to tumor necrosis factor alpha (TNFalpha). J Biol Chem 2007 1.09
15 Identification of novel deletion polymorphisms in breast cancer. Int J Oncol 2008 1.08
16 Protein kinase C delta induces transcription of the TP53 tumor suppressor gene by controlling death-promoting factor Btf in the apoptotic response to DNA damage. Mol Cell Biol 2007 1.08
17 Transforming mutations of RAC guanosine triphosphatases in human cancers. Proc Natl Acad Sci U S A 2013 1.07
18 Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest 2012 1.02
19 ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage. J Biol Chem 2009 1.02
20 Interference with BRCA2, which localizes to the centrosome during S and early M phase, leads to abnormal nuclear division. Biochem Biophys Res Commun 2007 1.01
21 Identification of a predictive gene expression signature of cervical lymph node metastasis in oral squamous cell carcinoma. Cancer Sci 2007 1.00
22 Human regulatory factor X 4 (RFX4) is a testis-specific dimeric DNA-binding protein that cooperates with other human RFX members. J Biol Chem 2001 1.00
23 IL12RB2 and ABCA1 genes are associated with susceptibility to radiation dermatitis. Clin Cancer Res 2008 0.99
24 Roles of interleukin-6 and parathyroid hormone-related peptide in osteoclast formation associated with oral cancers: significance of interleukin-6 synthesized by stromal cells in response to cancer cells. Am J Pathol 2009 0.99
25 Identification and characterization of the human protein kinase-like gene NTKL: mitosis-specific centrosomal localization of an alternatively spliced isoform. Genomics 2002 0.99
26 Down-regulation of keratin 4 and keratin 13 expression in oral squamous cell carcinoma and epithelial dysplasia: a clue for histopathogenesis. Histopathology 2011 0.98
27 The cell death machinery governed by the p53 tumor suppressor in response to DNA damage. Cancer Sci 2010 0.98
28 DNA damage signalling recruits RREB-1 to the p53 tumour suppressor promoter. Biochem J 2009 0.98
29 DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail. Cancer Lett 2013 0.94
30 A genome-wide association study identifies a genetic variant in the SIAH2 locus associated with hormonal receptor-positive breast cancer in Japanese. J Hum Genet 2012 0.94
31 Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer. Cancer Sci 2008 0.93
32 BRCA2 interacts with the cytoskeletal linker protein plectin to form a complex controlling centrosome localization. Cancer Sci 2009 0.93
33 Protein kinase C delta activates IkappaB-kinase alpha to induce the p53 tumor suppressor in response to oxidative stress. Cell Signal 2007 0.93
34 Protein kinase Cdelta activates RelA/p65 and nuclear factor-kappaB signaling in response to tumor necrosis factor-alpha. Cancer Res 2009 0.93
35 Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage. Mol Cell Biol 2006 0.92
36 High level of miR-21, miR-10b, and miR-31 expression in bilateral vs. unilateral breast carcinomas. Breast Cancer Res Treat 2011 0.90
37 Expression of basal cell keratin 15 and keratin 19 in oral squamous neoplasms represents diverse pathophysiologies. Histol Histopathol 2012 0.89
38 A functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress. Nucleic Acids Res 2008 0.89
39 Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer. J Hum Genet 2007 0.88
40 Expression profiling to predict postoperative prognosis for estrogen receptor-negative breast cancers by analysis of 25,344 genes on a cDNA microarray. Cancer Sci 2004 0.88
41 Genome-wide association study of breast cancer in the Japanese population. PLoS One 2013 0.87
42 BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK2. Cancer Res 2010 0.87
43 Enabling death by the Abl tyrosine kinase: mechanisms for nuclear shuttling of c-Abl in response to DNA damage. Cell Cycle 2005 0.87
44 Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome-wide expression profiling. Cancer Sci 2009 0.87
45 Conserved domains in the chicken homologue of BRCA2. Oncogene 2002 0.87
46 Programmed cell death 6, a novel p53-responsive gene, targets to the nucleus in the apoptotic response to DNA damage. Cancer Sci 2012 0.86
47 Identification of dihydropyrimidinase-related protein 4 as a novel target of the p53 tumor suppressor in the apoptotic response to DNA damage. Int J Cancer 2010 0.86
48 Molecular prediction of the therapeutic response to neoadjuvant chemotherapy in breast cancer. Breast Cancer 2008 0.85
49 Abnormal collagen deposition in fibromas from patient with juvenile hyaline fibromatosis. J Dermatol Sci 2009 0.85
50 Microsatellite instability caused by hMLH1 promoter methylation increases with tumor progression in right-sided sporadic colorectal cancer. Oncology 2005 0.85
51 BRCA2 phosphorylated by PLK1 moves to the midbody to regulate cytokinesis mediated by nonmuscle myosin IIC. Cancer Res 2014 0.85
52 Prevalence and differentiation of hereditary breast and ovarian cancers in Japan. Breast Cancer 2013 0.84
53 A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumor-suppressor gene. Int J Clin Oncol 2008 0.84
54 BRCA1-mediated ubiquitination inhibits topoisomerase II alpha activity in response to oxidative stress. Antioxid Redox Signal 2008 0.84
55 Accelerated growth of intestinal tumours after radiation exposure in Mlh1-knockout mice: evaluation of the late effect of radiation on a mouse model of HNPCC. Int J Exp Pathol 2006 0.83
56 Gene expression profiling of breast cancer. Breast Cancer 2006 0.82
57 Mutation analysis of the mel-18 gene that shows decreased expression in human breast cancer cell lines. Breast Cancer 2002 0.80
58 Gene-expression phenotypes for vascular invasiveness of hepatocellular carcinomas. Surgery 2009 0.80
59 Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage. Cancer Sci 2008 0.79
60 Prognostic value of matrix Gla protein in breast cancer. Mol Med Rep 2011 0.79
61 Identification of the molecular mechanisms for dedifferentiation at the invasion front of colorectal cancer by a gene expression analysis. Clin Cancer Res 2008 0.79
62 Gene expression patterns as marker for 5-year postoperative prognosis of primary breast cancers. J Cancer Res Clin Oncol 2004 0.79
63 Histological features of breast cancer, highly sensitive to chemotherapy. Breast Cancer 2007 0.79
64 D4S234E, a novel p53-responsive gene, induces apoptosis in response to DNA damage. Exp Cell Res 2010 0.79
65 The c-Abl tyrosine kinase stabilizes Pitx1 in the apoptotic response to DNA damage. Apoptosis 2010 0.79
66 Relatively common mutations of the Bloom syndrome gene in the Japanese population. Int J Mol Med 2004 0.78
67 Postoperative prognosis of node-negative breast cancers predicted by gene-expression profiling on a cDNA microarray of 25,344 genes. Breast Cancer 2005 0.77
68 PKCδ regulates Mdm2 independently of p53 in the apoptotic response to DNA damage. Mol Carcinog 2011 0.77
69 [Gene expression profiling for prediction of response to chemotherapy]. Gan To Kagaku Ryoho 2006 0.77
70 Immunohistochemical study of β-catenin and functionally related molecular markers in tongue squamous cell carcinoma and its correlation with cellular proliferation. Oncol Lett 2010 0.77
71 Frequency of immunohistochemical loss of mismatch repair protein in double primary cancers of the colorectum and stomach in Japan. Dis Colon Rectum 2006 0.77
72 Development of detection method for novel fusion gene using GeneChip exon array. J Clin Bioinforma 2014 0.77
73 Identification of Evi-1 as a novel effector of PKCδ in the apoptotic response to DNA damage. Biochim Biophys Acta 2011 0.77
74 Introduction and characterization of a polymerase-dead point mutation into the POLK gene in vertebrates. FEBS Lett 2009 0.75
75 Common peak approach using mass spectrometry data sets for predicting the effects of anticancer drugs on breast cancer. Cancer Inform 2007 0.75
76 Clinical impact of intraoperative detection of carcinoembryonic antigen mRNA in pleural lavage specimens from nonsmall cell lung cancer patients. Thorac Cardiovasc Surg 2012 0.75
77 [SNPs associated with adverse effects]. Gan To Kagaku Ryoho 2005 0.75
78 [Mechanisms of human breast cancer tumorigenesis: outline (including the molecular mechanism and multi-step of breast carcinogenesis)]. Nihon Rinsho 2012 0.75
79 [Prospects for genetic diagnosis]. Nihon Rinsho 2007 0.75
80 Prospective randomized phase II study determines the clinical usefulness of genetic biomarkers for sensitivity to primary chemotherapy with paclitaxel in breast cancer. Cancer Sci 2010 0.75
81 [PARP (poly(ADP-ribose) polymerase) family]. Nihon Rinsho 2012 0.75
82 [PARP inhibitors for cancer therapy]. Gan To Kagaku Ryoho 2011 0.75
83 Identifying haplotype block structure using an ancestor-derived model. J Hum Genet 2007 0.75
84 [Problem of the hereditary breast cancer screening; including the genetic diagnosis]. Nihon Rinsho 2012 0.75
85 [Gene testing of hereditary cancer on comprehensive gene medical examination support system]. Gan To Kagaku Ryoho 2005 0.75
86 [Clinical genetics for hereditary cancers: from the viewpoint of physicians working at a hospital specialized in cancer]. Gan To Kagaku Ryoho 2005 0.75
87 [Genomic based approach to individualized cancer therapy]. Nihon Rinsho 2010 0.75
88 [Gene expression profiling studies in breast cancer]. Nihon Rinsho 2012 0.75
89 Familial breast and ovarian cancers. Int J Clin Oncol 2004 0.75
90 Recurrence pattern and rapid intraoperative detection of carcinoembryonic antigen (CEA) mRNA in pleural lavage in patients with non-small cell lung cancer (NSCLC). Rinsho Byori 2008 0.75