Published in Genet Epidemiol on July 01, 2010
Performance of random forests and logic regression methods using mini-exome sequence data. BMC Proc (2011) 0.82
Importance measures for epistatic interactions in case-parent trios. Ann Hum Genet (2010) 0.79
Gene-Gene Interaction Among WNT Genes for Oral Cleft in Trios. Genet Epidemiol (2015) 0.78
Efficient simulation of epistatic interactions in case-parent trios. Hum Hered (2013) 0.77
Detecting disease variants in case-parent trio studies using the bioconductor software package trio. Genet Epidemiol (2014) 0.75
Finding the missing heritability of complex diseases. Nature (2009) 67.95
The human disease network. Proc Natl Acad Sci U S A (2007) 19.58
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA (2009) 12.35
Prepublication data sharing. Nature (2009) 12.24
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res (2002) 9.50
Comparative effectiveness of weight-loss interventions in clinical practice. N Engl J Med (2011) 7.81
Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet (2013) 7.44
Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia. Am J Hum Genet (2003) 6.63
Analysis and application of European genetic substructure using 300 K SNP information. PLoS Genet (2008) 6.42
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations. PLoS Genet (2009) 6.36
Intra-individual change over time in DNA methylation with familial clustering. JAMA (2008) 6.17
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. N Engl J Med (2003) 5.88
An integrated epigenetic and genetic approach to common human disease. Trends Genet (2004) 4.89
Implementing genomic medicine in the clinic: the future is here. Genet Med (2013) 4.89
Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet (2009) 4.78
Random-coil behavior and the dimensions of chemically unfolded proteins. Proc Natl Acad Sci U S A (2004) 4.44
Completing the map of human genetic variation. Nature (2007) 4.38
Whole-genome sequencing of a single proband together with linkage analysis identifies a Mendelian disease gene. PLoS Genet (2010) 4.29
Variants of DENND1B associated with asthma in children. N Engl J Med (2009) 4.18
Identifying interacting SNPs using Monte Carlo logic regression. Genet Epidemiol (2005) 4.18
Lipid adjustment in the analysis of environmental contaminants and human health risks. Environ Health Perspect (2005) 3.92
Personalized epigenomic signatures that are stable over time and covary with body mass index. Sci Transl Med (2010) 3.81
The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB. J Am Acad Dermatol (2008) 3.72
MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster. J Biol Chem (2007) 3.71
Detectable clonal mosaicism from birth to old age and its relationship to cancer. Nat Genet (2012) 3.68
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4. Nat Genet (2010) 3.63
Ascertainment adjustment in complex diseases. Genet Epidemiol (2002) 3.63
Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol (2012) 3.62
Mobile interspersed repeats are major structural variants in the human genome. Cell (2010) 3.60
Assessing the implementation of the chronic care model in quality improvement collaboratives. Health Serv Res (2005) 3.51
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene. Am J Hum Genet (2009) 3.41
Potential of fibroblast cell therapy for recessive dystrophic epidermolysis bullosa. J Invest Dermatol (2008) 3.34
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
The Centers for Mendelian Genomics: a new large-scale initiative to identify the genes underlying rare Mendelian conditions. Am J Med Genet A (2012) 3.12
Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am J Hum Genet (2005) 3.03
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Uncertainty in Rank Estimation: Implications for Value-Added Modeling Accountability Systems. J Educ Behav Stat (2002) 2.84
Significant linkage to compulsive hoarding on chromosome 14 in families with obsessive-compulsive disorder: results from the OCD Collaborative Genetics Study. Am J Psychiatry (2007) 2.84
Bone marrow transplantation for recessive dystrophic epidermolysis bullosa. N Engl J Med (2010) 2.82
Projecting the number of patients with end-stage renal disease in the United States to the year 2015. J Am Soc Nephrol (2005) 2.79
Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome. Am J Hum Genet (2003) 2.73
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. JAMA (2013) 2.58
A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol (2009) 2.53
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Lipoid proteinosis maps to 1q21 and is caused by mutations in the extracellular matrix protein 1 gene (ECM1). Hum Mol Genet (2002) 2.41
Imputation methods to improve inference in SNP association studies. Genet Epidemiol (2006) 2.41
Do patient consent procedures affect participation rates in health services research? Med Care (2002) 2.38
Microdeletions of 3q29 confer high risk for schizophrenia. Am J Hum Genet (2010) 2.38
Prediction of real-world functional disability in chronic mental disorders: a comparison of schizophrenia and bipolar disorder. Am J Psychiatry (2010) 2.35
Recurrent DNA inversion rearrangements in the human genome. Proc Natl Acad Sci U S A (2007) 2.29
DNA methylation regulates MicroRNA expression. Cancer Biol Ther (2007) 2.21
Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies. J Am Coll Cardiol (2010) 2.17
Prevalence and correlates of hoarding behavior in a community-based sample. Behav Res Ther (2008) 2.16
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet (2012) 2.15
PhenoDB: a new web-based tool for the collection, storage, and analysis of phenotypic features. Hum Mutat (2013) 2.13
Peroxisome biogenesis disorders. Annu Rev Genomics Hum Genet (2003) 2.09
Nonmelanoma skin cancer and risk for subsequent malignancy. J Natl Cancer Inst (2008) 2.08
Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1. Circulation (2007) 2.03
Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial. Ophthalmology (2011) 2.00
The identification of OCD-related subgroups based on comorbidity. Biol Psychiatry (2003) 2.00
The molecular basis of lipoid proteinosis: mutations in extracellular matrix protein 1. Exp Dermatol (2007) 1.98
Recurrent mutations in kindlin-1, a novel keratinocyte focal contact protein, in the autosomal recessive skin fragility and photosensitivity disorder, Kindler syndrome. J Invest Dermatol (2004) 1.95
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
Mutations in the gene encoding capillary morphogenesis protein 2 cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Am J Hum Genet (2003) 1.94
Independent but coordinated trials: insights from the practice-based Opportunities for Weight Reduction Trials Collaborative Research Group. Clin Trials (2010) 1.93
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci (2005) 1.91
Behavioral risk exposure and host genetics of susceptibility to HIV-1 infection. J Infect Dis (2005) 1.89
Overrepresentation of rare variants in a specific ethnic group may confuse interpretation of association analyses. Hum Mol Genet (2006) 1.84
Variation in a repeat sequence determines whether a common variant of the cystic fibrosis transmembrane conductance regulator gene is pathogenic or benign. Am J Hum Genet (2003) 1.81
Neuropsychological functioning in bipolar disorder and schizophrenia. Biol Psychiatry (2006) 1.80
A multilevel model to address batch effects in copy number estimation using SNP arrays. Biostatistics (2010) 1.76
Hidden Markov models for the assessment of chromosomal alterations using high-throughput SNP arrays. Ann Appl Stat (2008) 1.75
Association between IRF6 and nonsyndromic cleft lip with or without cleft palate in four populations. Genet Med (2007) 1.75
Quantifying uncertainty in genotype calls. Bioinformatics (2009) 1.74
Measuring the effectiveness of a collaborative for quality improvement in pediatric asthma care: does implementing the chronic care model improve processes and outcomes of care? Ambul Pediatr (2005) 1.72
Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis. Gastroenterology (2006) 1.71
Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation. J Invest Dermatol (2003) 1.67
The international dystrophic epidermolysis bullosa patient registry: an online database of dystrophic epidermolysis bullosa patients and their COL7A1 mutations. Hum Mutat (2011) 1.65
Recombination rates in admixed individuals identified by ancestry-based inference. Nat Genet (2011) 1.64
Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart. Genome Biol (2005) 1.64
New tools for Mendelian disease gene identification: PhenoDB variant analysis module; and GeneMatcher, a web-based tool for linking investigators with an interest in the same gene. Hum Mutat (2015) 1.64
Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population. Proc Natl Acad Sci U S A (2010) 1.64
Contact order and ab initio protein structure prediction. Protein Sci (2002) 1.59
European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups. Mol Med (2009) 1.59
Coffee intake and risk of hypertension: the Johns Hopkins precursors study. Arch Intern Med (2002) 1.58
"Genes to society"--the logic and process of the new curriculum for the Johns Hopkins University School of Medicine. Acad Med (2010) 1.57