Published in J Clin Immunol on June 23, 2010
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
A new statistical method for haplotype reconstruction from population data. Am J Hum Genet (2001) 59.30
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum (1997) 43.47
A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet (2003) 26.59
The DNA damage response: putting checkpoints in perspective. Nature (2000) 19.07
DNA damage and repair. Nature (2003) 6.76
The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell (1998) 6.58
Requirement of the MRN complex for ATM activation by DNA damage. EMBO J (2003) 6.23
Mechanism and regulation of class switch recombination. Annu Rev Immunol (2008) 5.98
Polymorphisms in DNA repair genes and associations with cancer risk. Cancer Epidemiol Biomarkers Prev (2002) 5.04
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science (2004) 4.58
Systemic lupus erythematosus. Cell (1996) 4.21
Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann Rheum Dis (1999) 1.75
Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet (1998) 1.73
Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis (2008) 1.64
The relationship between cancer and medication exposures in systemic lupus erythaematosus: a case-cohort study. Ann Rheum Dis (2007) 1.37
Breast cancer risk is associated with the genes encoding the DNA double-strand break repair Mre11/Rad50/Nbs1 complex. Cancer Epidemiol Biomarkers Prev (2007) 1.34
The genetics of human systemic lupus erythematosus. Trends Immunol (2003) 1.34
NBS1 and its functional role in the DNA damage response. DNA Repair (Amst) (2004) 1.30
Genetics of human systemic lupus erythematosus: the emerging picture. Curr Opin Immunol (2004) 1.19
Polymorphisms in the DNA repair genes XRCC1, APEX1, XRCC3 and NBS1, and the risk for lung cancer in never- and ever-smokers. Lung Cancer (2006) 1.14
Poly(ADP-ribosyl)ation in relation to cancer and autoimmune disease. Cell Mol Life Sci (2005) 1.11
Lupus and cancer. Lupus (2009) 1.07
Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus. Clin Exp Immunol (2004) 1.04
Neutrophils from systemic lupus erythematosus patients demonstrate increased nuclear DNA damage. Clin Exp Rheumatol (2002) 1.04
Lupus nephritis: the central role of nucleosomes revealed. Am J Pathol (2008) 1.03
Breast cancer risk in elderly women with systemic autoimmune rheumatic diseases: a population-based case-control study. Br J Cancer (2009) 1.01
Polymorphisms and haplotypes of the NBS1 gene are associated with risk of sporadic breast cancer in non-Hispanic white women <or=55 years. Carcinogenesis (2006) 1.00
Pathological lymphocyte activation by defective clearance of self-ligands in systemic lupus erythematosus. Rheumatology (Oxford) (2003) 0.98
Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology. Methods Mol Biol (2009) 0.95
Efficiency of the DNA repair and polymorphisms of the XRCC1, XRCC3 and XRCC4 DNA repair genes in systemic lupus erythematosus. Lupus (2008) 0.94
Polymorphisms and haplotypes of the NBS1 gene in childhood acute leukaemia. Eur J Cancer (2008) 0.92
TREX1 polymorphisms associated with autoantibodies in patients with systemic lupus erythematosus. Rheumatol Int (2007) 0.91
Fixing DNA breaks during class switch recombination. J Exp Med (2008) 0.90
Delayed repair of DNA damage by ionizing radiation in cells from patients with juvenile systemic lupus erythematosus and rheumatoid arthritis. Radiat Res (1997) 0.89
Possible association of the X-ray cross complementing gene 1 (XRCC1) Arg280His polymorphism as a risk for rheumatoid arthritis. Rheumatol Int (2005) 0.88
Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus. Immunology (2004) 0.87
Smoky coal exposure, NBS1 polymorphisms, p53 protein accumulation, and lung cancer risk in Xuan Wei, China. Lung Cancer (2005) 0.87
Immunogenicity of mitochondrial DNA modified by hydroxyl radical. Cell Immunol (2007) 0.86
New insights into the pathogenesis of systemic lupus erythematosus. Curr Rheumatol Rep (2005) 0.86
Immunogenicity of DNA damaged by reactive oxygen species--implications for anti-DNA antibodies in lupus. Free Radic Biol Med (1997) 0.86
Nijmegen breakage syndrome and DNA double strand break repair by NBS1 complex. Adv Biophys (2004) 0.85
Association of chondromodulin-II Val58Ile polymorphism with radiographic joint destruction in rheumatoid arthritis. J Rheumatol (2005) 0.84
Increased sensitivity of lymphocytes from patients with systemic autoimmune diseases to DNA alkylation by the methylating carcinogen N-methyl-N-nitrosourea. Ann Rheum Dis (1988) 0.83
A central role of nucleosomes in lupus nephritis. Ann N Y Acad Sci (2007) 0.82
Peripheral blood lymphocyte apoptosis and circulating dendritic cells in patients with systemic lupus erythematosus: correlation with immunological status and disease-related symptoms. Clin Rheumatol (2006) 0.80
Lupus-inducing drugs alter the structure of supercoiled circular DNA domains. Arthritis Rheum (1990) 0.78
Sensitivity of lymphocytes from patients with systemic lupus erythematosus to the induction of sister chromatid exchanges by alkylating agents and bromodeoxyuridine. Ann Rheum Dis (1987) 0.77
Poly(ADP-ribose) polymerase activity in systemic lupus erythematosus and systemic sclerosis. Hum Immunol (2009) 0.77
Repair of DNA damage induced in systemic lupus erythematosus skin fibroblasts by simulated sunlight. J Invest Dermatol (1992) 0.76
Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits. Nat Cell Biol (2002) 7.21
ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation. Nat Cell Biol (2008) 5.19
Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet (2011) 4.50
IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway. Cell (2007) 4.48
Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin. Mol Cell (2005) 3.89
PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J (2005) 3.10
Meta-analysis identifies common variants associated with body mass index in east Asians. Nat Genet (2012) 2.70
Imaging calcium entry sites and ribbon structures in two presynaptic cells. J Neurosci (2003) 2.32
Ethylene glycol induces calcium oxalate crystal deposition in Malpighian tubules: a Drosophila model for nephrolithiasis/urolithiasis. Kidney Int (2011) 2.28
Structural basis of a flavivirus recognized by its neutralizing antibody: solution structure of the domain III of the Japanese encephalitis virus envelope protein. J Biol Chem (2003) 2.09
Long contiguous stretches of homozygosity in the human genome. Hum Mutat (2006) 2.07
Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet (2012) 2.05
The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell (2012) 2.02
iSMART: an integrated cloud computing web server for traditional Chinese medicine for online virtual screening, de novo evolution and drug design. J Biomol Struct Dyn (2011) 1.72
Incidence of the mucopolysaccharidoses in Taiwan, 1984-2004. Am J Med Genet A (2009) 1.67
Down-regulation of myeloid cell leukemia-1 through inhibiting Erk/Pin 1 pathway by sorafenib facilitates chemosensitization in breast cancer. Cancer Res (2008) 1.56
Pompe disease in infants: improving the prognosis by newborn screening and early treatment. Pediatrics (2009) 1.56
Subunit 6 of the COP9 signalosome promotes tumorigenesis in mice through stabilization of MDM2 and is upregulated in human cancers. J Clin Invest (2011) 1.54
Mesenchymal stem cell insights: prospects in cardiovascular therapy. Cell Transplant (2014) 1.50
Tumor necrosis factor-α gene polymorphisms in age-related macular degeneration. Retina (2010) 1.45
Association of the neuronal nicotinic acetylcholine receptor subunit alpha4 polymorphisms with febrile convulsions. Epilepsia (2003) 1.44
Association between angiotensin I-converting enzyme gene insertion/deletion polymorphism and mitral valve prolapse syndrome. Am Heart J (2003) 1.43
Kabuki syndrome in a girl with mosaic 45,X/47,XXX and aortic coarctation. Fertil Steril (2007) 1.42
The rice pentatricopeptide repeat protein RF5 restores fertility in Hong-Lian cytoplasmic male-sterile lines via a complex with the glycine-rich protein GRP162. Plant Cell (2012) 1.41
Functional genomic analysis identified epidermal growth factor receptor activation as the most common genetic event in oral squamous cell carcinoma. Cancer Res (2009) 1.36
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production. J Virol (2003) 1.31
Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nat Genet (2012) 1.30
Trypsin-induced proteome alteration during cell subculture in mammalian cells. J Biomed Sci (2010) 1.29
Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3, and XRCC4 and their association with oral cancer in Taiwan. J Oral Pathol Med (2008) 1.29
Mutation analysis of Gaucher disease patients in Taiwan: high prevalence of the RecNciI and L444P mutations. Blood Cells Mol Dis (2006) 1.28
Laboratory-based surveillance and molecular epidemiology of influenza virus in Taiwan. J Clin Microbiol (2005) 1.26
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. Lung Cancer (2008) 1.25
Oxidative DNA damage in pterygium. Mol Vis (2005) 1.23
Genome-wide association study of diabetic retinopathy in a Taiwanese population. Ophthalmology (2011) 1.23
The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic. EMBO J (2003) 1.22
Ligand-based dual target drug design for H1N1: swine flu--a preliminary first study. J Biomol Struct Dyn (2009) 1.22
Investigation into potent inflammation inhibitors from traditional Chinese medicine. Chem Biol Drug Des (2011) 1.21
Structure-based and ligand-based drug design for HER 2 receptor. J Biomol Struct Dyn (2010) 1.21
Anti-SARS coronavirus 3C-like protease effects of Isatis indigotica root and plant-derived phenolic compounds. Antiviral Res (2005) 1.21
Identification of over-expressed proteins in oral squamous cell carcinoma (OSCC) patients by clinical proteomic analysis. Clin Chim Acta (2006) 1.20
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. Gigascience (2012) 1.18
The roles of human sucrose nonfermenting protein 2 homologue in the tumor-promoting functions of Rsf-1. Cancer Res (2008) 1.16
Association of phospholipase A2 receptor 1 polymorphisms with idiopathic membranous nephropathy in Chinese patients in Taiwan. J Biomed Sci (2010) 1.14
Vascular endothelial growth factor gene polymorphisms in age-related macular degeneration. Am J Ophthalmol (2008) 1.12
Aurora-A is a critical regulator of microtubule assembly and nuclear activity in mouse oocytes, fertilized eggs, and early embryos. Biol Reprod (2003) 1.11
Dually responsive multiblock copolymers via RAFT polymerization: Synthesis of temperature- and redox-responsive copolymers of PNIPAM and PDMAEMA. Macromolecules (2007) 1.11
Screening from the world's largest TCM database against H1N1 virus. J Biomol Struct Dyn (2011) 1.11
Rsf-1, a chromatin remodeling protein, induces DNA damage and promotes genomic instability. J Biol Chem (2010) 1.10
Tomato-based food products for prostate cancer prevention: what have we learned? Cancer Metastasis Rev (2010) 1.08
BRCA1 is required for meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes. Biol Reprod (2008) 1.07
The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development. Biol Reprod (2009) 1.07
Production of cloned transgenic cow expressing omega-3 fatty acids. Transgenic Res (2011) 1.07
RANKL increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation. J Cell Biochem (2011) 1.06
Endothelin-1 promotes MMP-13 production and migration in human chondrosarcoma cells through FAK/PI3K/Akt/mTOR pathways. J Cell Physiol (2012) 1.06
In silico pharmacology suggests ginger extracts may reduce stroke risks. Mol Biosyst (2011) 1.06
Potent inhibitor design against H1N1 swine influenza: structure-based and molecular dynamics analysis for M2 inhibitors from traditional Chinese medicine database. J Biomol Struct Dyn (2011) 1.05
Anti-apoptotic and pro-survival effects of exercise training on hypertensive hearts. J Appl Physiol (1985) (2011) 1.05
ISG15 over-expression inhibits replication of the Japanese encephalitis virus in human medulloblastoma cells. Antiviral Res (2009) 1.05
Aloe-emodin is an interferon-inducing agent with antiviral activity against Japanese encephalitis virus and enterovirus 71. Int J Antimicrob Agents (2008) 1.05
Talin-1 overexpression defines high risk for aggressive oral squamous cell carcinoma and promotes cancer metastasis. J Pathol (2011) 1.05
Bub1 prevents chromosome misalignment and precocious anaphase during mouse oocyte meiosis. Cell Cycle (2006) 1.04
An in vivo evaluation of a biodegradable genipin-cross-linked gelatin peripheral nerve guide conduit material. Biomaterials (2005) 1.04
Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci. Hypertension (2013) 1.03
Proteomic identification of salivary transferrin as a biomarker for early detection of oral cancer. Anal Chim Acta (2010) 1.03
NADPH oxidase-derived superoxide anion-induced apoptosis is mediated via the JNK-dependent activation of NF-κB in cardiomyocytes exposed to high glucose. J Cell Physiol (2012) 1.03
Influence of TAT-peptide polymerization on properties and transfection activity of TAT/DNA polyplexes. J Control Release (2005) 1.03
Association of the Slit and Trk-like 1 gene in Taiwanese patients with Tourette syndrome. Pediatr Neurol (2007) 1.03
Matrix metalloproteinase-9 polymorphism and risk of pelvic organ prolapse in Taiwanese women. Eur J Obstet Gynecol Reprod Biol (2010) 1.03
MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric division during mouse oocyte meiotic maturation. Cell Cycle (2007) 1.03
Retrospective evaluation of serum markers APRI and AST/ALT for assessing liver fibrosis and cirrhosis in chronic hepatitis B and C patients with hepatocellular carcinoma. Intern Med (2008) 1.03
Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not rabbit-human interspecies cloned embryos. Dev Dyn (2008) 1.03
Interleukin gene polymorphisms in age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 1.02
Molecular analysis of thiopurine S-methyltransferase alleles in South-east Asian populations. Pharmacogenetics (2002) 1.01
Rhein induces apoptosis in human breast cancer cells. Evid Based Complement Alternat Med (2011) 1.01
Lipopolysaccharide upregulates uPA, MMP-2 and MMP-9 via ERK1/2 signaling in H9c2 cardiomyoblast cells. Mol Cell Biochem (2009) 1.01
Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart. Mol Cell Biochem (2008) 1.00
Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells. Endocrinology (2008) 1.00
Replication and meta-analysis of GWAS identified susceptibility loci in Kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. PLoS One (2013) 0.99
Overexpression of a chromatin remodeling factor, RSF-1/HBXAP, correlates with aggressive oral squamous cell carcinoma. Am J Pathol (2011) 0.99
IGF-II/mannose-6-phosphate receptor signaling induced cell hypertrophy and atrial natriuretic peptide/BNP expression via Galphaq interaction and protein kinase C-alpha/CaMKII activation in H9c2 cardiomyoblast cells. J Endocrinol (2008) 0.99
Influence of nano-carrier architecture on in vitro siRNA delivery performance and in vivo biodistribution: polyplexes vs micelleplexes. ACS Nano (2011) 0.98
Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertilization, and early embryonic mitosis. Biol Reprod (2002) 0.98
Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine? J Biomol Struct Dyn (2012) 0.98
Schwann Cell Migration Induced by Earthworm Extract via Activation of PAs and MMP2/9 Mediated through ERK1/2 and p38. Evid Based Complement Alternat Med (2011) 0.98
DNA damage and endoplasmic reticulum stress mediated curcumin-induced cell cycle arrest and apoptosis in human lung carcinoma A-549 cells through the activation caspases cascade- and mitochondrial-dependent pathway. Cancer Lett (2008) 0.98
S100A8 is identified as a biomarker of HPV18-infected oral squamous cell carcinomas by suppression subtraction hybridization, clinical proteomics analysis, and immunohistochemistry staining. J Proteome Res (2007) 0.97
p53 gene codon 72 polymorphism but not tumor necrosis factor-alpha gene is associated with prostate cancer. Urol Int (2004) 0.97
Interleukin-4 gene, but not the interleukin-1 beta gene polymorphism, is associated with oral cancer. J Clin Lab Anal (2005) 0.97
Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer. Urology (2003) 0.97
Eccentric cardiac hypertrophy was induced by long-term intermittent hypoxia in rats. Exp Physiol (2006) 0.96
Association of TAP2 gene polymorphisms in Chinese patients with rheumatoid arthritis. Clin Rheumatol (2003) 0.96