Published in Cancer Res on July 20, 2010
Cisplatin resistance: a cellular self-defense mechanism resulting from multiple epigenetic and genetic changes. Pharmacol Rev (2012) 2.31
TRAP-1, the mitochondrial Hsp90. Biochim Biophys Acta (2011) 1.22
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease. Cell Death Dis (2013) 1.06
TRAP1 regulates proliferation, mitochondrial function, and has prognostic significance in NSCLC. Mol Cancer Res (2014) 0.99
TRAP1 and the proteasome regulatory particle TBP7/Rpt3 interact in the endoplasmic reticulum and control cellular ubiquitination of specific mitochondrial proteins. Cell Death Differ (2011) 0.96
Translational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1. Cell Death Dis (2013) 0.92
New insights into TRAP1 pathway. Am J Cancer Res (2012) 0.92
Analysis of apoptosis methods recently used in Cancer Research and Cell Death & Disease publications. Cell Death Dis (2012) 0.85
Oxidative metabolism drives inflammation-induced platinum resistance in human ovarian cancer. Cell Death Differ (2016) 0.84
Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma. Oncotarget (2015) 0.84
Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS One (2014) 0.83
Celastrol induces apoptosis of human osteosarcoma cells via the mitochondrial apoptotic pathway. Oncol Rep (2015) 0.83
TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma. Cell Death Differ (2016) 0.82
Mechanisms of Resistance to Hsp90 Inhibitor Drugs: A Complex Mosaic Emerges. Pharmaceuticals (Basel) (2011) 0.81
A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties. Proteome Sci (2010) 0.81
Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer. Oncotarget (2015) 0.80
Hsp90 regulation of mitochondrial protein folding: from organelle integrity to cellular homeostasis. Cell Mol Life Sci (2012) 0.80
Insulin-resistant conditions: A favorable milieu for aggressive drug-resistant malignancies. J Gastrointest Oncol (2011) 0.78
Sorcin modulates mitochondrial Ca(2+) handling and reduces apoptosis in neonatal rat cardiac myocytes. Am J Physiol Cell Physiol (2012) 0.78
Past, present, and emerging roles of mitochondrial heat shock protein TRAP1 in the metabolism and regulation of cancer stem cells. Cell Stress Chaperones (2016) 0.77
Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells. Mol Cancer (2014) 0.76
Overexpression of sorcin in multidrug-resistant human breast cancer. Oncol Lett (2014) 0.76
Whole-genome association analysis of pork meat pH revealed three significant regions and several potential genes in Finnish Yorkshire pigs. BMC Genet (2017) 0.75
The Chaperone TRAP1 As a Modulator of the Mitochondrial Adaptations in Cancer Cells. Front Oncol (2017) 0.75
TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma. Oncotarget (2017) 0.75
Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells. Cell Death Dis (2017) 0.75
Negative Regulation of Hepatic Inflammation by the Soluble Resistance-Related Calcium-Binding Protein via Signal Transducer and Activator of Transcription 3. Front Immunol (2017) 0.75
Italian cross-cultural adaptation and validation of the Oxford Shoulder Score. J Shoulder Elbow Surg (2009) 2.02
Control of PKA stability and signalling by the RING ligase praja2. Nat Cell Biol (2011) 1.66
Novel binding partners of Ldb1 are required for haematopoietic development. Development (2006) 1.63
Mitochondrial AKAP121 links cAMP and src signaling to oxidative metabolism. Mol Biol Cell (2005) 1.62
Epidermal growth factor receptor 1 expression is upregulated in undifferentiated thyroid carcinomas in humans. Thyroid (2011) 1.58
MDR1-P-glycoprotein behaves as an oncofetal protein that promotes cell survival in gastric cancer cells. Lab Invest (2012) 1.56
Antegrade dissection in laparoscopic cholecystectomy. JSLS (2007) 1.49
A cell proliferation and chromosomal instability signature in anaplastic thyroid carcinoma. Cancer Res (2007) 1.47
Multiple skeletal muscle metastases from colon carcinoma preceded by paraneoplastic dermatomyositis. Case Rep Med (2013) 1.44
Multistep, sequential control of the trafficking and function of the multiple sulfatase deficiency gene product, SUMF1 by PDI, ERGIC-53 and ERp44. Hum Mol Genet (2008) 1.43
Adaptation to oxidative stress, chemoresistance, and cell survival. Antioxid Redox Signal (2009) 1.42
Hb Southern Italy: coexistence of two missence mutations (the Hb Sun Prairie alpha2 130 Ala --> Pro and Hb Caserta alpha2 26 Ala --> Thr) in a single HBA2 gene. Br J Haematol (2008) 1.39
Expression and purification of the recombinant subunits of toluene/o-xylene monooxygenase and reconstitution of the active complex. Eur J Biochem (2002) 1.39
TRAP1, a novel mitochondrial chaperone responsible for multi-drug resistance and protection from apoptotis in human colorectal carcinoma cells. Cancer Lett (2009) 1.38
The mitochondrial chaperone TRAP1 promotes neoplastic growth by inhibiting succinate dehydrogenase. Cell Metab (2013) 1.36
Mitochondrial AKAP121 binds and targets protein tyrosine phosphatase D1, a novel positive regulator of src signaling. Mol Cell Biol (2004) 1.33
Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation. FEBS Lett (2005) 1.32
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry (2006) 1.32
Retracted ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells. J Cell Sci (2008) 1.30
Pseudomonas aeruginosa exploits lipid A and muropeptides modification as a strategy to lower innate immunity during cystic fibrosis lung infection. PLoS One (2009) 1.26
Phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas stutzeri OX1: interplay between two enzymes. Appl Environ Microbiol (2004) 1.26
Chromobox protein homologue 7 protein, with decreased expression in human carcinomas, positively regulates E-cadherin expression by interacting with the histone deacetylase 2 protein. Cancer Res (2009) 1.25
Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol (2010) 1.18
Mitochondrial localization unveils a novel role for GRK2 in organelle biogenesis. Cell Signal (2011) 1.10
AKAP121 downregulation impairs protective cAMP signals, promotes mitochondrial dysfunction, and increases oxidative stress. Cardiovasc Res (2010) 1.09
Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis. Cancer Res (2011) 1.08
Heat shock proteins, cell survival and drug resistance: the mitochondrial chaperone TRAP1, a potential novel target for ovarian cancer therapy. Gynecol Oncol (2009) 1.07
The role of the conserved residues His-246, His-199, and Tyr-255 in the catalysis of catechol 2,3-dioxygenase from Pseudomonas stutzeri OX1. J Biol Chem (2004) 1.06
Extra-mitochondrial localisation of frataxin and its association with IscU1 during enterocyte-like differentiation of the human colon adenocarcinoma cell line Caco-2. J Cell Sci (2005) 1.03
Protein-tyrosine phosphatase PTPD1 regulates focal adhesion kinase autophosphorylation and cell migration. J Biol Chem (2008) 1.03
A-kinase anchor protein 84/121 are targeted to mitochondria and mitotic spindles by overlapping amino-terminal motifs. J Mol Biol (2002) 1.00
Reverse transcriptase inhibitors induce cell differentiation and enhance the immunogenic phenotype in human renal clear-cell carcinoma. Int J Cancer (2008) 1.00
Thermal stability and aggregation of sulfolobus solfataricus beta-glycosidase are dependent upon the N-epsilon-methylation of specific lysyl residues: critical role of in vivo post-translational modifications. J Biol Chem (2003) 0.99
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth. Nat Commun (2013) 0.99
Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi. Nature (2013) 0.98
PTPD1 supports receptor stability and mitogenic signaling in bladder cancer cells. J Biol Chem (2010) 0.98
The cellular amount of the common gamma-chain influences spontaneous or induced cell proliferation. J Immunol (2009) 0.97
Sulfatase modifying factor 1 trafficking through the cells: from endoplasmic reticulum to the endoplasmic reticulum. EMBO J (2007) 0.97
Differential apoptosis markers in human keloids and hypertrophic scars fibroblasts. Mol Cell Biochem (2009) 0.97
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma. J Clin Endocrinol Metab (2005) 0.96
The HIV-1 transactivator factor (Tat) induces enterocyte apoptosis through a redox-mediated mechanism. PLoS One (2011) 0.96
Laparoscopic appendectomy in Italy: an appraisal of 26,863 cases. J Laparoendosc Adv Surg Tech A (2004) 0.95
The 3'-untranslated region directs ribosomal protein-encoding mRNAs to specific cytoplasmic regions. Biochim Biophys Acta (2006) 0.95
Difficult cholecystectomies: validity of the laparoscopic approach. JSLS (2003) 0.94
The FCP1 phosphatase interacts with RNA polymerase II and with MEP50 a component of the methylosome complex involved in the assembly of snRNP. Nucleic Acids Res (2003) 0.93
Notch signaling modulates hypoxia-induced neuroendocrine differentiation of human prostate cancer cells. Mol Cancer Res (2011) 0.93
Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1. Mol Oncol (2013) 0.93
Reactive oxygen species, Ki-Ras, and mitochondrial superoxide dismutase cooperate in nerve growth factor-induced differentiation of PC12 cells. J Biol Chem (2010) 0.92
New insights into TRAP1 pathway. Am J Cancer Res (2012) 0.92
The cytosolic ribonuclease inhibitor contributes to intracellular redox homeostasis. FEBS Lett (2007) 0.92
Pancreatic cancer-derived S-100A8 N-terminal peptide: a diabetes cause? Clin Chim Acta (2006) 0.92
Biological properties of a human compact anti-ErbB2 antibody. Carcinogenesis (2005) 0.92
Umbilical port-site complications in laparoscopic cholecystectomy: role of topical antibiotic therapy. JSLS (2008) 0.91
A complex of α6 integrin and E-cadherin drives liver metastasis of colorectal cancer cells through hepatic angiopoietin-like 6. EMBO Mol Med (2012) 0.91
Bidimensional tandem mass spectrometry for selective identification of nitration sites in proteins. Anal Chem (2007) 0.90
Erlotinib enhances the proapoptotic activity of cytotoxic agents and synergizes with paclitaxel in poorly-differentiated thyroid carcinoma cells. Anticancer Res (2010) 0.90
Effects of the known pathogenic mutations on the aggregation pathway of the amyloidogenic peptide of apolipoprotein A-I. J Mol Biol (2011) 0.90
The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. PLoS One (2012) 0.90
Role of MT1-MMP in the osteogenic differentiation. Bone (2008) 0.89
Topological investigation of amyloid fibrils obtained from beta2-microglobulin. Protein Sci (2002) 0.89
The Cu,Zn superoxide dismutase in neuroblastoma SK-N-BE cells is exported by a microvesicles dependent pathway. Brain Res Mol Brain Res (2003) 0.89
Exploring the mechanism of formation of native-like and precursor amyloid oligomers for the native acylphosphatase from Sulfolobus solfataricus. Structure (2006) 0.88
A novel toll-like receptor 9 agonist cooperates with trastuzumab in trastuzumab-resistant breast tumors through multiple mechanisms of action. Clin Cancer Res (2009) 0.88
Proteomics of beta2-microglobulin amyloid fibrils. Biochim Biophys Acta (2005) 0.88
Hb Foggia or alpha 117(GH5)Phe -> Ser: a new alpha 2 globin allele affecting the alpha Hb-AHSP interaction. Haematologica (2008) 0.88
Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1). Int J Biochem Cell Biol (2009) 0.87
PED/PEA-15 controls fibroblast motility and wound closure by ERK1/2-dependent mechanisms. J Cell Physiol (2012) 0.87
Structural and biochemical characterization of a new type of lectin isolated from carp eggs. Biochem J (2003) 0.87
Functional amyloids in insect immune response. Insect Biochem Mol Biol (2011) 0.87