Published in Integr Biol (Camb) on July 26, 2010
Optical probes and techniques for O2 measurement in live cells and tissue. Cell Mol Life Sci (2012) 1.02
Oxygen versus Reactive Oxygen in the Regulation of HIF-1α: The Balance Tips. Biochem Res Int (2012) 0.95
Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria. Cell Mol Life Sci (2010) 0.93
Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. Biosci Rep (2012) 0.93
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci U S A (2006) 4.08
Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha. Science (2003) 3.91
Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation (2005) 2.99
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. Gastroenterology (2007) 2.87
Hypoxia-responsive transcription factors. Pflugers Arch (2005) 2.64
Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol (2010) 2.18
Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival. PLoS One (2011) 1.86
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia. Mol Cell Biol (2011) 1.81
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2009) 1.78
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology (2010) 1.64
Regulation of oxygen distribution in tissues by endothelial nitric oxide. Circ Res (2009) 1.61
Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J (2006) 1.61
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A (2003) 1.52
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome. Am J Respir Crit Care Med (2006) 1.50
Analysis of mitochondrial function using phosphorescent oxygen-sensitive probes. Nat Protoc (2006) 1.44
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest (2011) 1.44
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells. Proc Natl Acad Sci U S A (2009) 1.38
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem (2003) 1.33
Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. J Biol Chem (2010) 1.33
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Kidney Int (2003) 1.21
G2019S leucine-rich repeat kinase 2 causes uncoupling protein-mediated mitochondrial depolarization. Hum Mol Genet (2012) 1.21
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. J Immunol (2010) 1.20
Analysis of intracellular oxygen and metabolic responses of mammalian cells by time-resolved fluorometry. Anal Chem (2007) 1.17
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells. J Immunol (2010) 1.12
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proc Natl Acad Sci U S A (2013) 1.12
Gremlin plays a key role in the pathogenesis of pulmonary hypertension. Circulation (2012) 1.11
Investigation of drug-induced mitochondrial toxicity using fluorescence-based oxygen-sensitive probes. Toxicol Sci (2006) 1.10
Carbon dioxide-sensing in organisms and its implications for human disease. Cell Mol Life Sci (2013) 1.10
15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure. J Am Soc Nephrol (2002) 1.08
Targeting the HIF pathway in inflammation and immunity. Curr Opin Pharmacol (2013) 1.07
c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res (2004) 1.05
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network. J Cell Sci (2013) 1.03
Intracellular O2 sensing probe based on cell-penetrating phosphorescent nanoparticles. ACS Nano (2011) 1.03
Optical probes and techniques for O2 measurement in live cells and tissue. Cell Mol Life Sci (2012) 1.02
Fluorescence-based cell viability screening assays using water-soluble oxygen probes. J Biomol Screen (2003) 1.01
Sensing intracellular oxygen using near-infrared phosphorescent probes and live-cell fluorescence imaging. Am J Physiol Regul Integr Comp Physiol (2006) 1.01
Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung. Am J Respir Crit Care Med (2008) 0.97
A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun (2007) 0.97
Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner. Am J Physiol Cell Physiol (2005) 0.96
Hypoxia increases antibiotic resistance in Pseudomonas aeruginosa through altering the composition of multidrug efflux pumps. Antimicrob Agents Chemother (2012) 0.96
Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia. J Biol Chem (2010) 0.95
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. Arthritis Res Ther (2009) 0.95
Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor. J Immunol (2005) 0.94
Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway. Antioxid Redox Signal (2009) 0.94
NFκB and HIF display synergistic behaviour during hypoxic inflammation. Cell Mol Life Sci (2011) 0.94
Hypoxia, innate immunity and infection in the lung. Respir Physiol Neurobiol (2010) 0.93
Fluorescence based oxygen uptake analysis in the study of metabolic responses to apoptosis induction. J Immunol Methods (2005) 0.93
Intracellular oxygen-sensitive phosphorescent probes based on cell-penetrating peptides. Anal Biochem (2009) 0.93
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock (2011) 0.93
Bafilomycin A1 activates respiration of neuronal cells via uncoupling associated with flickering depolarization of mitochondria. Cell Mol Life Sci (2010) 0.93
Bafilomycin A1 activates HIF-dependent signalling in human colon cancer cells via mitochondrial uncoupling. Biosci Rep (2012) 0.93
Hydroxylases as therapeutic targets in inflammatory bowel disease. Lab Invest (2013) 0.92
Hypercapnia induces cleavage and nuclear localization of RelB protein, giving insight into CO2 sensing and signaling. J Biol Chem (2012) 0.92
Dynamics of intracellular oxygen in PC12 Cells upon stimulation of neurotransmission. J Biol Chem (2007) 0.91
SUMO, hypoxia and the regulation of metabolism. Biochem Soc Trans (2008) 0.89
Assessment of cellular oxygen gradients with a panel of phosphorescent oxygen-sensitive probes. Anal Chem (2012) 0.89
Alterations in oxidative gene expression in equine skeletal muscle following exercise and training. Physiol Genomics (2009) 0.88
The use of a fluorescence-based oxygen uptake assay in the analysis of cytotoxicity. Toxicol In Vitro (2006) 0.87
Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults. Biol Neonate (2006) 0.87
A low-volume platform for cell-respirometric screening based on quenched-luminescence oxygen sensing. Biosens Bioelectron (2004) 0.86
Hydroxylase-dependent regulation of the NF-κB pathway. Biol Chem (2013) 0.86
Optical oxygen microrespirometry as a platform for environmental toxicology and animal model studies. Environ Sci Technol (2005) 0.86
On-chip electrochemical microsystems for measurements of copper and conductivity in artificial seawater. Talanta (2013) 0.86
Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest (2016) 0.86
Hypoxic regulation of NF-kappaB signaling. Methods Enzymol (2007) 0.85
Imaging of neurosphere oxygenation with phosphorescent probes. Biomaterials (2013) 0.85
Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism. J Cell Physiol (2006) 0.85
In vivo imaging of brain metabolism activity using a phosphorescent oxygen-sensitive probe. J Neurosci Methods (2013) 0.83
The impact of hypoxia on cell death pathways. Biochem Soc Trans (2013) 0.83
Hypoxia modulates infection of epithelial cells by Pseudomonas aeruginosa. PLoS One (2013) 0.83
Availability of the key metabolic substrates dictates the respiratory response of cancer cells to the mitochondrial uncoupling. Biochim Biophys Acta (2013) 0.83
Chronic hypoxia leads to a glycolytic phenotype and suppressed HIF-2 signaling in PC12 cells. Biochim Biophys Acta (2013) 0.82
Lower expression of Nrf2 mRNA in older donor livers: a possible contributor to increased ischemia-reperfusion injury? Transplantation (2007) 0.82
Cell-penetrating conjugates of coproporphyrins with oligoarginine peptides: rational design and application for sensing intracellular O2. Bioconjug Chem (2011) 0.81
In vitro analysis of cell metabolism using a long-decay pH-sensitive lanthanide probe and extracellular acidification assay. Anal Biochem (2009) 0.81
Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha. J Interferon Cytokine Res (2005) 0.80
Homogeneous assays for cellular proteases employing the platinum(II)-coproporphyrin label and time-resolved phosphorescence. Anal Biochem (2005) 0.80
Bactenecin 7 peptide fragment as a tool for intracellular delivery of a phosphorescent oxygen sensor. FEBS J (2010) 0.80
Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles. Cell Mol Life Sci (2014) 0.79
Mitochondria, oxygen sensing, and the regulation of HIF-2alpha. Focus on "Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line". Am J Physiol Cell Physiol (2008) 0.79
Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochim Biophys Acta (2010) 0.79
Imaging of cellular oxygen and analysis of metabolic responses of mammalian cells. Methods Mol Biol (2010) 0.79
Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea. FASEB J (2010) 0.79
Phosphorescent oxygen sensors based on nanostructured polyolefin substrates. Anal Chem (2010) 0.79
Performance evaluation of the phosphorescent porphyrin label: solid-phase immunoassay of alpha-fetoprotein. Anal Chem (2002) 0.78
Analysis of activity and inhibition of oxygen-dependent enzymes by optical respirometry on the LightCycler system. Anal Biochem (2009) 0.78
Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion. Mol Cell Biochem (2012) 0.78
Phosphorescent metalloporphyrins as labels in time-resolved luminescence microscopy: effect of mounting on emission intensity. Microsc Res Tech (2002) 0.77
Multi-parametric O₂ imaging in three-dimensional neural cell models with the phosphorescent probes. Methods Mol Biol (2015) 0.77
Genome-wide investigation of cellular targets and mode of action of the antifungal bacterial metabolite 2,4-diacetylphloroglucinol in Saccharomyces cerevisiae. FEMS Yeast Res (2013) 0.77
Rapid high-throughput assessment of aerobic bacteria in complex samples by fluorescence-based oxygen respirometry. Appl Environ Microbiol (2006) 0.77
Synthesis and evaluation of phosphorescent oligonucleotide probes for hybridisation assays. Nucleic Acids Res (2002) 0.77
Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. Adv Exp Med Biol (2002) 0.77
A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network. J Cell Sci (2015) 0.77
Complexes of Ir(III)-octaethylporphyrin with peptides as probes for sensing cellular O2. Chembiochem (2012) 0.76