Published in Cell Mol Life Sci on November 09, 2011
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Hypoxia, mitochondrial dysfunction and synovial invasiveness in rheumatoid arthritis. Nat Rev Rheumatol (2016) 0.86
Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest (2016) 0.86
Hypoxia-inducible factor (HIF) network: insights from mathematical models. Cell Commun Signal (2013) 0.85
Distinct phenotypes of human prostate cancer cells associate with different adaptation to hypoxia and pro-inflammatory gene expression. PLoS One (2014) 0.84
Chorioamnionitis (ChA) modifies CX3CL1 (fractalkine) production by human amniotic epithelial cells (HAEC) under normoxic and hypoxic conditions. J Inflamm (Lond) (2014) 0.81
Myeloid knockout of HIF-1 α does not markedly affect hemorrhage/resuscitation-induced inflammation and hepatic injury. Mediators Inflamm (2014) 0.81
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Development of Antioxidant COX-2 Inhibitors as Radioprotective Agents for Radiation Therapy-A Hypothesis-Driven Review. Antioxidants (Basel) (2016) 0.76
Partial Enteral Nutrition Mitigated Ischemia/Reperfusion-Induced Damage of Rat Small Intestinal Barrier. Nutrients (2016) 0.75
Perfluorocarbon-Loaded Lipid Nanocapsules to Assess the Dependence of U87-Human Glioblastoma Tumor pO2 on In Vitro Expansion Conditions. PLoS One (2016) 0.75
Perturbation of neddylation-dependent NF-κB responses in the intestinal epithelium drives apoptosis and inhibits resolution of mucosal inflammation. Mol Biol Cell (2016) 0.75
Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity. Proc Natl Acad Sci U S A (2006) 4.08
Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha. Science (2003) 3.91
Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome. Circulation (2005) 2.99
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. Gastroenterology (2007) 2.87
Hypoxia-responsive transcription factors. Pflugers Arch (2005) 2.64
The mammalian MAPK/ERK pathway exhibits properties of a negative feedback amplifier. Sci Signal (2010) 2.40
Hypoxia: an alarm signal during intestinal inflammation. Nat Rev Gastroenterol Hepatol (2010) 2.18
A sphingosine-1-phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ Res (2006) 2.12
MicroRNA-155 promotes resolution of hypoxia-inducible factor 1alpha activity during prolonged hypoxia. Mol Cell Biol (2011) 1.81
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury. Proc Natl Acad Sci U S A (2009) 1.78
Raf family kinases: old dogs have learned new tricks. Genes Cancer (2011) 1.72
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology (2010) 1.64
Regulation of oxygen distribution in tissues by endothelial nitric oxide. Circ Res (2009) 1.61
Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury. FASEB J (2006) 1.61
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia. Proc Natl Acad Sci U S A (2003) 1.52
Predictors of elevated nuclear factor-kappaB-dependent genes in obstructive sleep apnea syndrome. Am J Respir Crit Care Med (2006) 1.50
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice. J Clin Invest (2011) 1.44
Regulation of arterial tone by KV1 potassium channels. Circ Res (2005) 1.43
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells. Proc Natl Acad Sci U S A (2009) 1.38
The role of HIF-1 alpha in transcriptional regulation of the proximal tubular epithelial cell response to hypoxia. J Biol Chem (2003) 1.33
Stabilization of hypoxia-inducible factor-1alpha protein in hypoxia occurs independently of mitochondrial reactive oxygen species production. J Biol Chem (2010) 1.33
Robotic multiwell planar patch-clamp for native and primary mammalian cells. Nat Protoc (2009) 1.25
Modification of the transcriptomic response to renal ischemia/reperfusion injury by lipoxin analog. Kidney Int (2003) 1.21
An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. J Immunol (2010) 1.20
NF-κB links CO2 sensing to innate immunity and inflammation in mammalian cells. J Immunol (2010) 1.12
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proc Natl Acad Sci U S A (2013) 1.12
Gremlin plays a key role in the pathogenesis of pulmonary hypertension. Circulation (2012) 1.11
Carbon dioxide-sensing in organisms and its implications for human disease. Cell Mol Life Sci (2013) 1.10
15-Epi-16-(para-fluorophenoxy)-lipoxin A(4)-methyl ester, a synthetic analogue of 15-epi-lipoxin A(4), is protective in experimental ischemic acute renal failure. J Am Soc Nephrol (2002) 1.08
Targeting the HIF pathway in inflammation and immunity. Curr Opin Pharmacol (2013) 1.07
c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia. Cancer Res (2004) 1.05
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network. J Cell Sci (2013) 1.03
ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2. J Cell Sci (2012) 1.01
Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung. Am J Respir Crit Care Med (2008) 0.97
A critical role for p38 map kinase in NF-kappaB signaling during intermittent hypoxia/reoxygenation. Biochem Biophys Res Commun (2007) 0.97
Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner. Am J Physiol Cell Physiol (2005) 0.96
Hypoxia increases antibiotic resistance in Pseudomonas aeruginosa through altering the composition of multidrug efflux pumps. Antimicrob Agents Chemother (2012) 0.96
Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia. J Biol Chem (2010) 0.95
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. Arthritis Res Ther (2009) 0.95
Potentiation of glucocorticoid activity in hypoxia through induction of the glucocorticoid receptor. J Immunol (2005) 0.94
Hypoxia activates NF-kappaB-dependent gene expression through the canonical signaling pathway. Antioxid Redox Signal (2009) 0.94
K(v)1.5 potassium channel gene regulation by Sp1 transcription factor and oxidative stress. Am J Physiol Heart Circ Physiol (2007) 0.94
Hypoxia, innate immunity and infection in the lung. Respir Physiol Neurobiol (2010) 0.93
The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock (2011) 0.93
Hypercapnia induces cleavage and nuclear localization of RelB protein, giving insight into CO2 sensing and signaling. J Biol Chem (2012) 0.92
Hydroxylases as therapeutic targets in inflammatory bowel disease. Lab Invest (2013) 0.92
Extracellular signal-regulated kinase regulates RhoA activation and tumor cell plasticity by inhibiting guanine exchange factor H1 activity. Mol Cell Biol (2013) 0.92
SUMO, hypoxia and the regulation of metabolism. Biochem Soc Trans (2008) 0.89
Alterations in oxidative gene expression in equine skeletal muscle following exercise and training. Physiol Genomics (2009) 0.88
Effects of heat shock and hypoxia on neonatal neutrophil lipopolysaccharide responses: altered apoptosis, Toll-like receptor-4 and CD11b expression compared with adults. Biol Neonate (2006) 0.87
Hydroxylase-dependent regulation of the NF-κB pathway. Biol Chem (2013) 0.86
Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest (2016) 0.86
Hypoxic regulation of NF-kappaB signaling. Methods Enzymol (2007) 0.85
Hypoxia-inducible factor (HIF) network: insights from mathematical models. Cell Commun Signal (2013) 0.85
Regulation of protein phosphatase 1gamma activity in hypoxia through increased interaction with NIPP1: implications for cellular metabolism. J Cell Physiol (2006) 0.85
The impact of hypoxia on cell death pathways. Biochem Soc Trans (2013) 0.83
Hypoxia modulates infection of epithelial cells by Pseudomonas aeruginosa. PLoS One (2013) 0.83
Lower expression of Nrf2 mRNA in older donor livers: a possible contributor to increased ischemia-reperfusion injury? Transplantation (2007) 0.82
Cholera toxin potentiates influences of IFN-gamma through activation of NF-kappaB and release of tumor necrosis factor-alpha. J Interferon Cytokine Res (2005) 0.80
Monitoring of cell oxygenation and responses to metabolic stimulation by intracellular oxygen sensing technique. Integr Biol (Camb) (2010) 0.80
Extracellular calcium depletion transiently elevates oxygen consumption in neurosecretory PC12 cells through activation of mitochondrial Na+/Ca2+ exchange. Biochim Biophys Acta (2010) 0.79
Mitochondria, oxygen sensing, and the regulation of HIF-2alpha. Focus on "Induction of HIF-2alpha is dependent on mitochondrial O2 consumption in an O2-sensitive adrenomedullary chromaffin cell line". Am J Physiol Cell Physiol (2008) 0.79
Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea. FASEB J (2010) 0.79
Glucose reintroduction triggers the activation of Nrf2 during experimental ischemia reperfusion. Mol Cell Biochem (2012) 0.78
Catching transcriptional regulation by thermostatistical modeling. Phys Biol (2012) 0.78
Potassium channels at the beginnings of cell proliferation. J Physiol (2005) 0.77
A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network. J Cell Sci (2015) 0.77
Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate. Cell Mol Life Sci (2015) 0.77
Endothelial COX-2 induction by hypoxia liberates 6-keto-PGF1 alpha, a potent epithelial secretagogue. Adv Exp Med Biol (2002) 0.77
Monitoring of transcriptional dynamics of HIF and NFκB activities. Methods Mol Biol (2014) 0.77
Identification of cyclic AMP response element-binding protein-dependent transcriptional responses in hypoxia by microarray analysis. Methods Enzymol (2004) 0.75
Enhanced sensitivity of protein kinase B/Akt to insulin in hypoxia is independent of HIF1alpha and promotes cell viability. Eur J Cell Biol (2007) 0.75
Resistance to caspase-dependent, hypoxia-induced apoptosis is not hypoxia-inducible factor-1 alpha mediated in prostate carcinoma cells. Cancer (2005) 0.75