Published in Cell Mol Life Sci on August 04, 2010
Histone methylation: a dynamic mark in health, disease and inheritance. Nat Rev Genet (2012) 5.42
Bittersweet memories: linking metabolism to epigenetics through O-GlcNAcylation. Nat Rev Mol Cell Biol (2012) 2.74
Operating on chromatin, a colorful language where context matters. J Mol Biol (2011) 2.00
Proteome-wide post-translational modification statistics: frequency analysis and curation of the swiss-prot database. Sci Rep (2011) 1.92
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods Enzymol (2012) 1.83
Mass spectrometry-based proteomics: existing capabilities and future directions. Chem Soc Rev (2012) 1.47
Quantitative proteomic analysis of histone modifications. Chem Rev (2015) 1.32
SnapShot: histone modifications. Cell (2014) 1.20
EpiProfile Quantifies Histone Peptides With Modifications by Extracting Retention Time and Intensity in High-resolution Mass Spectra. Mol Cell Proteomics (2015) 1.09
Stable-isotope-labeled histone peptide library for histone post-translational modification and variant quantification by mass spectrometry. Mol Cell Proteomics (2014) 1.08
Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH) Analysis for Characterization and Quantification of Histone Post-translational Modifications. Mol Cell Proteomics (2015) 1.06
Histones: at the crossroads of peptide and protein chemistry. Chem Rev (2014) 1.01
Peptide identification by tandem mass spectrometry with alternate fragmentation modes. Mol Cell Proteomics (2012) 0.91
Evaluation of proteomic search engines for the analysis of histone modifications. J Proteome Res (2014) 0.89
Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation. J Virol (2013) 0.87
Extensive post-translational modification of active and inactivated forms of endogenous p53. Mol Cell Proteomics (2013) 0.86
Characterization of histone post-translational modifications during virus infection using mass spectrometry-based proteomics. Methods (2015) 0.84
Bottom-up and middle-down proteomics have comparable accuracies in defining histone post-translational modification relative abundance and stoichiometry. Anal Chem (2015) 0.83
Cigarette smoke induces distinct histone modifications in lung cells: implications for the pathogenesis of COPD and lung cancer. J Proteome Res (2013) 0.83
Combining genomic and proteomic approaches for epigenetics research. Epigenomics (2013) 0.83
The histone methyltransferase DOT1L: regulatory functions and a cancer therapy target. Am J Cancer Res (2015) 0.82
Cytoplasmic protein methylation is essential for neural crest migration. J Cell Biol (2013) 0.82
Finding combinatorial histone code by semi-supervised biclustering. BMC Genomics (2012) 0.80
Epigenetics of the failing heart. Heart Fail Rev (2015) 0.77
Establishing and characterizing a new primary effusion lymphoma cell line harboring Kaposi's sarcoma-associated herpesvirus. Infect Agent Cancer (2016) 0.77
Multiplexed data independent acquisition (MSX-DIA) applied by high resolution mass spectrometry improves quantification quality for the analysis of histone peptides. Proteomics (2016) 0.76
Abnormal levels of histone methylation in the retinas of diabetic rats are reversed by minocycline treatment. Sci Rep (2017) 0.75
Histone modification profiling reveals differential signatures associated with human embryonic stem cell self-renewal and differentiation. Proteomics (2016) 0.75
Application of dual reading domains as novel reagents in chromatin biology reveals a new H3K9me3 and H3K36me2/3 bivalent chromatin state. Epigenetics Chromatin (2017) 0.75
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med (2012) 11.14
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med (2011) 3.82
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Asymmetrically modified nucleosomes. Cell (2012) 2.79
High throughput characterization of combinatorial histone codes. Mol Cell Proteomics (2009) 2.52
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature (2010) 2.49
In vivo residue-specific histone methylation dynamics. J Biol Chem (2009) 2.33
Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res (2004) 2.28
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell (2011) 2.27
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature (2010) 2.20
One-pot shotgun quantitative mass spectrometry characterization of histones. J Proteome Res (2009) 2.13
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol (2010) 2.07
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Mol Cell (2011) 1.96
Retracted Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature (2010) 1.92
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods Enzymol (2012) 1.83
Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Mol Cell (2012) 1.79
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J (2007) 1.55
A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron transfer dissociation tandem mass spectrometry. Mol Cell Proteomics (2009) 1.51
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem (2006) 1.50
Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Mol Cell Biol (2009) 1.49
Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics (2011) 1.39
Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol Cell Proteomics (2009) 1.39
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol (2013) 1.33
Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval. J Proteome Res (2009) 1.33
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proc Natl Acad Sci U S A (2012) 1.28
Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila. Nat Struct Mol Biol (2013) 1.26
Proteomic characterization of novel histone post-translational modifications. Epigenetics Chromatin (2013) 1.26
Global secretome analysis identifies novel mediators of bone metastasis. Cell Res (2012) 1.22
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. Epigenetics (2012) 1.19
Quantitative dynamics of the link between cellular metabolism and histone acetylation. J Biol Chem (2013) 1.19
Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. Genome Biol (2012) 1.18
Origins and formation of histone methylation across the human cell cycle. Mol Cell Biol (2012) 1.16
Simian virus 40 small t antigen mediates conformation-dependent transfer of protein phosphatase 2A onto the androgen receptor. Mol Cell Biol (2005) 1.13
Analysis of histones in Xenopus laevis. II. mass spectrometry reveals an index of cell type-specific modifications on H3 and H4. J Biol Chem (2008) 1.12
Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses. Nat Struct Mol Biol (2012) 1.11
Mild performic acid oxidation enhances chromatographic and top down mass spectrometric analyses of histones. Mol Cell Proteomics (2007) 1.11
A novel approach for untargeted post-translational modification identification using integer linear optimization and tandem mass spectrometry. Mol Cell Proteomics (2010) 1.11
Protein quantification across hundreds of experimental conditions. Proc Natl Acad Sci U S A (2009) 1.10
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes Dev (2012) 1.10
Large-scale global identification of protein lysine methylation in vivo. Epigenetics (2013) 1.09
A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics Chromatin (2013) 1.06
Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics Chromatin (2010) 1.03
BclAF1 restriction factor is neutralized by proteasomal degradation and microRNA repression during human cytomegalovirus infection. Proc Natl Acad Sci U S A (2012) 1.01
H4K20 methylation regulates quiescence and chromatin compaction. Mol Biol Cell (2013) 0.99
H3R42me2a is a histone modification with positive transcriptional effects. Proc Natl Acad Sci U S A (2013) 0.97
Systems-wide proteomic characterization of combinatorial post-translational modification patterns. Expert Rev Proteomics (2010) 0.96
Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation. J Biol Chem (2006) 0.96
Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity. J Biol Chem (2011) 0.95
Novel protein identification methods for biomarker discovery via a proteomic analysis of periodontally healthy and diseased gingival crevicular fluid samples. J Clin Periodontol (2011) 0.95
Quantitative proteomics reveals direct and indirect alterations in the histone code following methyltransferase knockdown. Mol Biosyst (2010) 0.94
Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates. Epigenetics (2010) 0.94
Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. J Cell Sci (2011) 0.93
Proteomic interrogation of human chromatin. PLoS One (2011) 0.93
Poly-acetylated chromatin signatures are preferred epitopes for site-specific histone H4 acetyl antibodies. Sci Rep (2012) 0.93
Site-specific casein kinase 1epsilon-dependent phosphorylation of Dishevelled modulates beta-catenin signaling. FEBS J (2006) 0.91
Evaluation of proteomic search engines for the analysis of histone modifications. J Proteome Res (2014) 0.89
Memory acquisition and retrieval impact different epigenetic processes that regulate gene expression. BMC Genomics (2015) 0.89
Drawbacks in the use of unconventional hydrophobic anhydrides for histone derivatization in bottom-up proteomics PTM analysis. Proteomics (2015) 0.87
Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. J Proteome Res (2012) 0.87
Electron transfer dissociation facilitates sequencing of adenosine diphosphate-ribosylated peptides. Anal Chem (2010) 0.87
Neutron-encoded mass signatures for quantitative top-down proteomics. Anal Chem (2014) 0.87
Collective mass spectrometry approaches reveal broad and combinatorial modification of high mobility group protein A1a. J Am Soc Mass Spectrom (2010) 0.86
Revealing histone variant induced changes via quantitative proteomics. Crit Rev Biochem Mol Biol (2011) 0.86
Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature (2013) 0.85
Dysregulation of PAD4-mediated citrullination of nuclear GSK3β activates TGF-β signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proc Natl Acad Sci U S A (2013) 0.85
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics (2013) 0.85
Modern approaches for investigating epigenetic signaling pathways. J Appl Physiol (1985) (2010) 0.84
Mass spectrometric analysis of histone proteoforms. Annu Rev Anal Chem (Palo Alto Calif) (2014) 0.83
Combining genomic and proteomic approaches for epigenetics research. Epigenomics (2013) 0.83
Comprehending dynamic protein methylation with mass spectrometry. Curr Opin Chem Biol (2013) 0.82
Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. Curr Protoc Protein Sci (2014) 0.82
Discovery of lysine post-translational modifications through mass spectrometric detection. Essays Biochem (2012) 0.82
Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination. Mol Cell Proteomics (2014) 0.82
High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. J Proteome Res (2014) 0.81
Proteomic analysis of the SIRT6 interactome: novel links to genome maintenance and cellular stress signaling. Sci Rep (2013) 0.80
A proteomic glimpse into the initial global epigenetic changes during HIV infection. Proteomics (2014) 0.80
PILOT_PROTEIN: identification of unmodified and modified proteins via high-resolution mass spectrometry and mixed-integer linear optimization. J Proteome Res (2012) 0.79
Quantitative proteomic approaches to studying histone modifications. Curr Chem Genomics (2011) 0.79
Discovery of biomarker combinations that predict periodontal health or disease with high accuracy from GCF samples based on high-throughput proteomic analysis and mixed-integer linear optimization. J Clin Periodontol (2012) 0.78
A core viral protein binds host nucleosomes to sequester immune danger signals. Nature (2016) 0.78
Improvement in the apparent mass resolution of oligonucleotides by using 12C/14N-enriched samples. Anal Chem (2002) 0.78
Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. Methods Mol Biol (2013) 0.78
In vivo proximity labeling for the detection of protein-protein and protein-RNA interactions. J Proteome Res (2014) 0.77
Validation of protein acetylation by mass spectrometry. Methods Mol Biol (2013) 0.77
De novo peptide design and experimental validation of histone methyltransferase inhibitors. PLoS One (2014) 0.75
Assessment of quantification precision of histone post-translational modifications by using an ion trap and down to 50,000 cells as starting material. J Proteome Res (2017) 0.75