Published in Mol Cell Proteomics on June 14, 2007
Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle. Mol Cell Biol (2007) 2.43
Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry. J Biol Chem (2008) 2.28
Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation. Proc Natl Acad Sci U S A (2010) 1.87
Tissue-specific expression and post-translational modification of histone H3 variants. J Proteome Res (2008) 1.84
Preferential dimethylation of histone H4 lysine 20 by Suv4-20. J Biol Chem (2008) 1.58
Top-down mass spectrometry: recent developments, applications and perspectives. Analyst (2011) 1.50
Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals. Mol Cell Proteomics (2010) 1.43
An integrated top-down and bottom-up strategy for broadly characterizing protein isoforms and modifications. J Proteome Res (2009) 1.21
Top Down proteomics: facts and perspectives. Biochem Biophys Res Commun (2014) 1.14
Robust methods for purification of histones from cultured mammalian cells with the preservation of their native modifications. Nucleic Acids Res (2009) 1.06
Lymphocyte development requires S-nitrosoglutathione reductase. J Immunol (2010) 1.05
Comparing and combining capillary electrophoresis electrospray ionization mass spectrometry and nano-liquid chromatography electrospray ionization mass spectrometry for the characterization of post-translationally modified histones. Mol Cell Proteomics (2013) 0.96
Chemical and biochemical approaches in the study of histone methylation and demethylation. Med Res Rev (2012) 0.85
Global histone profiling by LC-FTMS after inhibition and knockdown of deacetylases in human cells. J Chromatogr B Analyt Technol Biomed Life Sci (2009) 0.84
Site specific identification of endogenous S-nitrosocysteine proteomes. J Proteomics (2013) 0.84
Middle-Down and Top-Down Mass Spectrometric Analysis of Co-occurring Histone Modifications. Curr Protoc Protein Sci (2014) 0.82
Solid-phase capture for the detection and relative quantification of S-nitrosoproteins by mass spectrometry. Methods (2012) 0.79
Differential alkylation-based redox proteomics - Lessons learnt. Redox Biol (2015) 0.77
Sample preparation for the analysis of membrane proteomes by mass spectrometry. Protein Cell (2012) 0.75
Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells. J Immunol (2016) 0.75
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med (2012) 11.14
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature (2005) 6.40
Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma. Science (2013) 6.29
Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature (2011) 4.84
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
Precision proteomics: the case for high resolution and high mass accuracy. Proc Natl Acad Sci U S A (2008) 4.00
A monovalent streptavidin with a single femtomolar biotin binding site. Nat Methods (2006) 3.89
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization. Nat Med (2011) 3.82
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. Nat Chem Biol (2011) 3.60
Pervasive combinatorial modification of histone H3 in human cells. Nat Methods (2007) 3.54
Proteoform: a single term describing protein complexity. Nat Methods (2013) 3.48
Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation. Cell (2008) 3.09
Quantitative analysis of modified proteins and their positional isomers by tandem mass spectrometry: human histone H4. Anal Chem (2006) 3.08
Deconstruction of iterative multidomain polyketide synthase function. Science (2008) 3.02
Expression patterns and post-translational modifications associated with mammalian histone H3 variants. J Biol Chem (2005) 3.00
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation. Nature (2012) 2.96
Functional CpG methylation system in a social insect. Science (2006) 2.95
Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity. Science (2004) 2.83
Asymmetrically modified nucleosomes. Cell (2012) 2.79
The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood (2010) 2.71
Decoding protein modifications using top-down mass spectrometry. Nat Methods (2007) 2.62
High throughput characterization of combinatorial histone codes. Mol Cell Proteomics (2009) 2.52
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature (2010) 2.49
Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle. Mol Cell Biol (2007) 2.43
Shotgun annotation of histone modifications: a new approach for streamlined characterization of proteins by top down mass spectrometry. J Am Chem Soc (2004) 2.36
ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry. Nucleic Acids Res (2007) 2.35
In vivo residue-specific histone methylation dynamics. J Biol Chem (2009) 2.33
Mass spectrometric characterization of human histone H3: a bird's eye view. J Proteome Res (2006) 2.29
Mass spectrometry analysis of Arabidopsis histone H3 reveals distinct combinations of post-translational modifications. Nucleic Acids Res (2004) 2.28
Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry. J Biol Chem (2008) 2.28
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell (2011) 2.27
Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. Mol Cell (2009) 2.27
Facile detection of acyl and peptidyl intermediates on thiotemplate carrier domains via phosphopantetheinyl elimination reactions during tandem mass spectrometry. Biochemistry (2006) 2.22
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature (2010) 2.20
Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic. Proc Natl Acad Sci U S A (2006) 2.19
One-pot shotgun quantitative mass spectrometry characterization of histones. J Proteome Res (2009) 2.13
Precise characterization of human histones in the H2A gene family by top down mass spectrometry. J Proteome Res (2006) 2.09
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat Immunol (2010) 2.07
Negative regulation of NF-kappaB action by Set9-mediated lysine methylation of the RelA subunit. EMBO J (2009) 2.05
Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase. Proc Natl Acad Sci U S A (2005) 2.03
ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry. Nucleic Acids Res (2004) 2.03
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Mol Cell (2011) 1.96
Retracted Branched tricarboxylic acid metabolism in Plasmodium falciparum. Nature (2010) 1.92
Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci U S A (2005) 1.91
Precise and parallel characterization of coding polymorphisms, alternative splicing, and modifications in human proteins by mass spectrometry. Mol Cell Proteomics (2005) 1.86
Web and database software for identification of intact proteins using "top down" mass spectrometry. Anal Chem (2003) 1.85
Tissue-specific expression and post-translational modification of histone H3 variants. J Proteome Res (2008) 1.84
Examining histone posttranslational modification patterns by high-resolution mass spectrometry. Methods Enzymol (2012) 1.83
Proteome-wide prediction of acetylation substrates. Proc Natl Acad Sci U S A (2009) 1.81
Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis. Proc Natl Acad Sci U S A (2006) 1.80
Histone H3 lysine 56 methylation regulates DNA replication through its interaction with PCNA. Mol Cell (2012) 1.79
Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production. J Am Chem Soc (2005) 1.76
Unusual transformations in the biosynthesis of the antibiotic phosphinothricin tripeptide. Nat Chem Biol (2007) 1.72
A novel histone deacetylase pathway regulates mitosis by modulating Aurora B kinase activity. Genes Dev (2006) 1.70
Complete protein characterization using top-down mass spectrometry and ultraviolet photodissociation. J Am Chem Soc (2013) 1.69
A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome. J Am Soc Mass Spectrom (2009) 1.65
Processing complex mixtures of intact proteins for direct analysis by mass spectrometry. Anal Chem (2002) 1.63
Mass spectrometric interrogation of thioester-bound intermediates in the initial stages of epothilone biosynthesis. Chem Biol (2004) 1.61
Top-down proteomics on a chromatographic time scale using linear ion trap fourier transform hybrid mass spectrometers. Anal Chem (2007) 1.60
Dichlorination of a pyrrolyl-S-carrier protein by FADH2-dependent halogenase PltA during pyoluteorin biosynthesis. Proc Natl Acad Sci U S A (2005) 1.58
Preferential dimethylation of histone H4 lysine 20 by Suv4-20. J Biol Chem (2008) 1.58
Top down mass spectrometry of < 60-kDa proteins from Methanosarcina acetivorans using quadrupole FRMS with automated octopole collisionally activated dissociation. Mol Cell Proteomics (2006) 1.57
Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units. Proc Natl Acad Sci U S A (2006) 1.56
Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J (2007) 1.55
Gene-specific characterization of human histone H2B by electron capture dissociation. J Proteome Res (2006) 1.53
A mixed integer linear optimization framework for the identification and quantification of targeted post-translational modifications of highly modified proteins using multiplexed electron transfer dissociation tandem mass spectrometry. Mol Cell Proteomics (2009) 1.51
The significance, development and progress of high-throughput combinatorial histone code analysis. Cell Mol Life Sci (2010) 1.51
Oncogene-induced cellular senescence elicits an anti-Warburg effect. Proteomics (2013) 1.50
Identification of histone H3 lysine 36 acetylation as a highly conserved histone modification. J Biol Chem (2006) 1.50
Chromatin-specific remodeling by HMGB1 and linker histone H1 silences proinflammatory genes during endotoxin tolerance. Mol Cell Biol (2009) 1.49
Heterologous production of fosfomycin and identification of the minimal biosynthetic gene cluster. Chem Biol (2006) 1.47
Construction of a hybrid quadrupole/Fourier transform ion cyclotron resonance mass spectrometer for versatile MS/MS above 10 kDa. J Am Soc Mass Spectrom (2004) 1.46
"Proteotyping": population proteomics of human leukocytes using top down mass spectrometry. Anal Chem (2008) 1.46
Modifications of H3 and H4 during chromatin replication, nucleosome assembly, and histone exchange. J Biol Chem (2006) 1.42
Cloning, expression, and biochemical characterization of Streptomyces rubellomurinus genes required for biosynthesis of antimalarial compound FR900098. Chem Biol (2008) 1.41
Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa. Anal Chem (2010) 1.40
Global assessment of combinatorial post-translational modification of core histones in yeast using contemporary mass spectrometry. LYS4 trimethylation correlates with degree of acetylation on the same H3 tail. J Biol Chem (2007) 1.40
Combinatorial profiling of chromatin binding modules reveals multisite discrimination. Nat Chem Biol (2010) 1.39
Dissecting non-ribosomal and polyketide biosynthetic machineries using electrospray ionization Fourier-Transform mass spectrometry. Nat Prod Rep (2006) 1.39
Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics (2011) 1.39
Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol Cell Proteomics (2009) 1.39
Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair. J Mol Cell Biol (2013) 1.37
A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis. Proc Natl Acad Sci U S A (2008) 1.36
Large-scale top-down proteomics of the human proteome: membrane proteins, mitochondria, and senescence. Mol Cell Proteomics (2013) 1.33
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency. Nat Cell Biol (2013) 1.33
Tandem mass spectrometry with ultrahigh mass accuracy clarifies peptide identification by database retrieval. J Proteome Res (2009) 1.33
New and automated MSn approaches for top-down identification of modified proteins. J Am Soc Mass Spectrom (2005) 1.33
On the scalability and requirements of whole protein mass spectrometry. Anal Chem (2011) 1.31
Interrogation of global active site occupancy of a fungal iterative polyketide synthase reveals strategies for maintaining biosynthetic fidelity. J Am Chem Soc (2012) 1.29