Published in BMC Cancer on August 13, 2010
miRNA-mRNA correlation-network modules in human prostate cancer and the differences between primary and metastatic tumor subtypes. PLoS One (2012) 0.99
Network topology reveals key cardiovascular disease genes. PLoS One (2013) 0.96
Mouse models for colorectal cancer. Am J Cancer Res (2013) 0.91
Regulation of gene expression in ovarian cancer cells by luteinizing hormone receptor expression and activation. BMC Cancer (2011) 0.86
Frequent alteration of the tumor suppressor gene APC in sporadic canine colorectal tumors. PLoS One (2012) 0.81
Cancer driver-passenger distinction via sporadic human and dog cancer comparison: a proof-of-principle study with colorectal cancer. Oncogene (2013) 0.80
Inactivation of tumor suppressor gene pten in early and advanced gallbladder cancer. Diagn Pathol (2015) 0.76
Palmoplantar Keratoderma in Slurp2-Deficient Mice. J Invest Dermatol (2015) 0.76
The modularity and dynamicity of miRNA-mRNA interactions in high-grade serous ovarian carcinomas and the prognostic implication. Comput Biol Chem (2016) 0.75
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
The sequence of the human genome. Science (2001) 101.55
The consensus coding sequences of human breast and colorectal cancers. Science (2006) 60.02
Patterns of somatic mutation in human cancer genomes. Nature (2007) 38.41
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science (2008) 36.02
Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell (2003) 25.94
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma. Proc Natl Acad Sci U S A (2007) 18.83
TGFbeta signaling in growth control, cancer, and heritable disorders. Cell (2000) 12.38
Linking colorectal cancer to Wnt signaling. Cell (2000) 11.58
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science (1996) 11.13
Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (1990) 8.32
Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus. Science (2000) 7.25
Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers. Science (1991) 6.15
Human and mouse genomic sequences reveal extensive breakpoint reuse in mammalian evolution. Proc Natl Acad Sci U S A (2003) 4.54
Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell (1998) 4.22
The ABC of APC. Hum Mol Genet (2001) 4.16
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nat Genet (1996) 4.09
A sequence-level map of chromosomal breakpoints in the MCF-7 breast cancer cell line yields insights into the evolution of a cancer genome. Genome Res (2008) 4.06
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene. Nature (1997) 3.57
Mammalian retroelements. Genome Res (2002) 3.49
The significance of unstable chromosomes in colorectal cancer. Nat Rev Cancer (2003) 3.21
Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation. Cancer Res (2007) 2.97
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
High-resolution genomic and expression analyses of copy number alterations in breast tumors. Genes Chromosomes Cancer (2008) 2.46
The onset and extent of genomic instability in sporadic colorectal tumor progression. Proc Natl Acad Sci U S A (1999) 2.41
ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias. Proc Natl Acad Sci U S A (1993) 2.19
ApcMin: a mouse model for intestinal and mammary tumorigenesis. Eur J Cancer (1995) 1.94
Frequency of Smad gene mutations in human cancers. Cancer Res (1997) 1.73
Human, mouse, and rat genome large-scale rearrangements: stability versus speciation. Genome Res (2004) 1.63
APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice. J Cell Biol (2007) 1.60
Transcriptional profiles of intestinal tumors in Apc(Min) mice are unique from those of embryonic intestine and identify novel gene targets dysregulated in human colorectal tumors. Cancer Res (2005) 1.58
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. Cancer Res (1999) 1.48
High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. Oncogene (2006) 1.46
Chromosomal breakpoints in primary colon cancer cluster at sites of structural variants in the genome. Cancer Res (2008) 1.44
A resistant genetic background leading to incomplete penetrance of intestinal neoplasia and reduced loss of heterozygosity in ApcMin/+ mice. Proc Natl Acad Sci U S A (1998) 1.32
Aneuploidy-dependent massive deregulation of the cellular transcriptome and apparent divergence of the Wnt/beta-catenin signaling pathway in human rectal carcinomas. Cancer Res (2006) 1.31
Stage-specific alterations of the genome, transcriptome, and proteome during colorectal carcinogenesis. Genes Chromosomes Cancer (2007) 1.26
Genome-wide differences between microsatellite stable and unstable colorectal tumors. Carcinogenesis (2005) 1.23
Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function. Proc Natl Acad Sci U S A (2004) 1.20
Evolution of the tumor suppressor BRCA1 locus in primates: implications for cancer predisposition. Hum Mol Genet (2004) 1.17
Long-lived Min mice develop advanced intestinal cancers through a genetically conservative pathway. Cancer Res (2009) 1.10
Adenomatous polyposis coli/beta-catenin interaction and downstream targets: altered gene expression in gastrointestinal tumors. Clin Colorectal Cancer (2003) 1.04
Basic principles and technologies for deciphering the genetic map of cancer. World J Surg (2009) 0.96
DNA mismatch repair and colorectal cancer. J Pathol (1998) 0.96
Copy number abnormalities in sporadic canine colorectal cancers. Genome Res (2010) 0.95
Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus. Genomics (2004) 0.92
DA and Xiao-two giant and composite LTR-retrotransposon-like elements identified in the human genome. Genomics (2008) 0.89
Studying the consequences of immediate loss of gene function in the intestine: APC. Biochem Soc Trans (2005) 0.81
Mouse Models of Intestinal Cancer. Comp Med (2004) 0.80
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med (2008) 10.12
Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios. Science (2003) 9.20
A catalog of reference genomes from the human microbiome. Science (2010) 8.10
End-sequence profiling: sequence-based analysis of aberrant genomes. Proc Natl Acad Sci U S A (2003) 7.70
Celecoxib for the prevention of sporadic colorectal adenomas. N Engl J Med (2006) 7.62
Prior image constrained compressed sensing (PICCS): a method to accurately reconstruct dynamic CT images from highly undersampled projection data sets. Med Phys (2008) 7.52
A Sanger/pyrosequencing hybrid approach for the generation of high-quality draft assemblies of marine microbial genomes. Proc Natl Acad Sci U S A (2006) 7.17
Celecoxib for the prevention of colorectal adenomatous polyps. N Engl J Med (2006) 6.15
CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. Science (2009) 5.00
A physical map of the mouse genome. Nature (2002) 4.97
Within the fold: assessing differential expression measures and reproducibility in microarray assays. Genome Biol (2002) 4.67
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology (2009) 4.08
The dynamic genome of Hydra. Nature (2010) 4.00
Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res (2005) 3.79
The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell (2010) 3.52
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A (2009) 3.39
Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases. Structure (2004) 3.31
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer. Clin Cancer Res (2009) 3.08
Genomic and functional adaptation in surface ocean planktonic prokaryotes. Nature (2010) 2.93
Molecular staging for survival prediction of colorectal cancer patients. J Clin Oncol (2005) 2.88
Osteopontin identified as lead marker of colon cancer progression, using pooled sample expression profiling. J Natl Cancer Inst (2002) 2.77
Potent immunogenicity and efficacy of a universal influenza vaccine candidate comprising a recombinant fusion protein linking influenza M2e to the TLR5 ligand flagellin. Vaccine (2007) 2.76
Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clin Cancer Res (2006) 2.70
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome Biol (2007) 2.70
Transcriptome-guided characterization of genomic rearrangements in a breast cancer cell line. Proc Natl Acad Sci U S A (2009) 2.57
Five-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib Trial. Cancer Prev Res (Phila) (2009) 2.46
Sequence survey of receptor tyrosine kinases reveals mutations in glioblastomas. Proc Natl Acad Sci U S A (2005) 2.38
Genome sequence of the necrotrophic plant pathogen Pythium ultimum reveals original pathogenicity mechanisms and effector repertoire. Genome Biol (2010) 2.36
Correlation of osteopontin protein expression and pathological stage across a wide variety of tumor histologies. Clin Cancer Res (2004) 2.33
Identification of substrates of human protein-tyrosine phosphatase PTPN22. J Biol Chem (2006) 2.29
Biochemical characterization of the human copper transporter Ctr1. J Biol Chem (2001) 2.28
Multi-platform, multi-site, microarray-based human tumor classification. Am J Pathol (2004) 2.14
Abdominal CT with model-based iterative reconstruction (MBIR): initial results of a prospective trial comparing ultralow-dose with standard-dose imaging. AJR Am J Roentgenol (2012) 2.13
Phylogenomics of nonavian reptiles and the structure of the ancestral amniote genome. Proc Natl Acad Sci U S A (2007) 2.09
Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem (2005) 2.07
Analysis of primate genomic variation reveals a repeat-driven expansion of the human genome. Genome Res (2003) 2.07
Unraveling the genomic mosaic of a ubiquitous genus of marine cyanobacteria. Genome Biol (2008) 2.06
EMT is the dominant program in human colon cancer. BMC Med Genomics (2011) 2.05
Extracellular matrix protein betaig-h3/TGFBI promotes metastasis of colon cancer by enhancing cell extravasation. Genes Dev (2008) 2.00
A set of BAC clones spanning the human genome. Nucleic Acids Res (2004) 2.00
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome. Cancer Res (2008) 1.99
Correlations of DDAH1 transcript variants with human endothelial asymmetric dimethylarginine metabolizing activity. Am J Hypertens (2013) 1.98
High temporal resolution and streak-free four-dimensional cone-beam computed tomography. Phys Med Biol (2008) 1.96
Prognostic and predictive value of a malignancy-risk gene signature in early-stage non-small cell lung cancer. J Natl Cancer Inst (2011) 1.92
1-Mb resolution array-based comparative genomic hybridization using a BAC clone set optimized for cancer gene analysis. Genome Res (2003) 1.90
KRAS mutation is associated with lung metastasis in patients with curatively resected colorectal cancer. Clin Cancer Res (2011) 1.87
Comparative analysis of Alu repeats in primate genomes. Genome Res (2009) 1.85
Proliferative genes dominate malignancy-risk gene signature in histologically-normal breast tissue. Breast Cancer Res Treat (2009) 1.83
Lineage-specific expansions of retroviral insertions within the genomes of African great apes but not humans and orangutans. PLoS Biol (2005) 1.82
Using comparative genomics to reorder the human genome sequence into a virtual sheep genome. Genome Biol (2007) 1.79
Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein. Science (2003) 1.77
Undetermined focal liver lesions on gray-scale ultrasound in patients with fatty liver: characterization with contrast-enhanced ultrasound. J Gastroenterol Hepatol (2008) 1.74
Vaccination with recombinant fusion proteins incorporating Toll-like receptor ligands induces rapid cellular and humoral immunity. Vaccine (2006) 1.74
A preliminary comparative analysis of primate segmental duplications shows elevated substitution rates and a great-ape expansion of intrachromosomal duplications. Genome Res (2006) 1.69
A West Nile virus recombinant protein vaccine that coactivates innate and adaptive immunity. J Infect Dis (2007) 1.68
Analysis of the Pseudoalteromonas tunicata genome reveals properties of a surface-associated life style in the marine environment. PLoS One (2008) 1.60
A physical map of the bovine genome. Genome Biol (2007) 1.56
Complete genome sequence of Erythrobacter litoralis HTCC2594. J Bacteriol (2009) 1.54
Characterization of a marine gammaproteobacterium capable of aerobic anoxygenic photosynthesis. Proc Natl Acad Sci U S A (2007) 1.51
Proteomic contributions to personalized cancer care. Mol Cell Proteomics (2008) 1.46
Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses. Immunology (2013) 1.46
Finding complex biological relationships in recent PubMed articles using Bio-LDA. PLoS One (2011) 1.45
Efficacious recombinant influenza vaccines produced by high yield bacterial expression: a solution to global pandemic and seasonal needs. PLoS One (2008) 1.44
DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers. Clin Cancer Res (2008) 1.44
Mariprofundus ferrooxydans PV-1 the first genome of a marine Fe(II) oxidizing Zetaproteobacterium. PLoS One (2011) 1.40
Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin. Gastroenterology (2011) 1.40
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer. Cancer Res (2012) 1.39
Surgical treatment and long-term outcomes of thalamic cavernous malformations. World Neurosurg (2012) 1.38
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. J Clin Invest (2010) 1.35
Reduced image noise at low-dose multidetector CT of the abdomen with prior image constrained compressed sensing algorithm. Radiology (2011) 1.34
Complete genome sequence of Robiginitalea biformata HTCC2501. J Bacteriol (2009) 1.33
Increased Src activity disrupts cadherin/catenin-mediated homotypic adhesion in human colon cancer and transformed rodent cells. Cancer Res (2002) 1.33
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing. BMC Bioinformatics (2008) 1.32
Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer. Gut (2011) 1.32
Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int (2002) 1.31
Effects of p38 MAPK inhibition on early stages of diabetic retinopathy and sensory nerve function. Invest Ophthalmol Vis Sci (2010) 1.31
Prior image constrained compressed sensing: implementation and performance evaluation. Med Phys (2012) 1.30
Temporal resolution improvement using PICCS in MDCT cardiac imaging. Med Phys (2009) 1.28
CD24: from A to Z. Cell Mol Immunol (2010) 1.28
Osteopontin induces multiple changes in gene expression that reflect the six "hallmarks of cancer" in a model of breast cancer progression. Mol Carcinog (2005) 1.28
Muscle wasting and interleukin-6-induced atrogin-I expression in the cachectic Apc ( Min/+ ) mouse. Pflugers Arch (2008) 1.27
Understanding the complexity of temperature dynamics in Xinjiang, China, from multitemporal scale and spatial perspectives. ScientificWorldJournal (2013) 1.26
Long-term results of transanal excision after neoadjuvant chemoradiation for T2 and T3 adenocarcinomas of the rectum. J Gastrointest Surg (2008) 1.25
Claudin-1 up-regulates the repressor ZEB-1 to inhibit E-cadherin expression in colon cancer cells. Gastroenterology (2011) 1.25
A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation. Int J Radiat Oncol Biol Phys (2009) 1.24
Improved outcome with cytoreduction versus embolization for symptomatic hepatic metastases of carcinoid and neuroendocrine tumors. Ann Surg Oncol (2006) 1.23
Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice. Proc Natl Acad Sci U S A (2009) 1.22
Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. Biochemistry (2004) 1.22
Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients. Diabetes (2002) 1.22
Secondary cytoreductive surgery for patients with relapsed epithelial ovarian carcinoma: who benefits? Cancer (2004) 1.21
Time-resolved interventional cardiac C-arm cone-beam CT: an application of the PICCS algorithm. IEEE Trans Med Imaging (2011) 1.20