Published in Ann N Y Acad Sci on August 01, 2010
Glutathione in cancer cell death. Cancers (Basel) (2011) 1.15
Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death. Antioxid Redox Signal (2011) 1.01
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol (2012) 0.97
Disulfide bonds within the C2 domain of RAGE play key roles in its dimerization and biogenesis. PLoS One (2012) 0.83
Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells. Free Radic Biol Med (2015) 0.82
Glutathione and redox signaling in substance abuse. Biomed Pharmacother (2014) 0.76
Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π. JCI Insight (2016) 0.75
Inhibition of endotoxin-induced airway epithelial cell injury by a novel family of pyrrol derivates. Lab Invest (2016) 0.75
NOX enzymes and the biology of reactive oxygen. Nat Rev Immunol (2004) 12.93
Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science (1995) 8.17
High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med (2005) 7.20
Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science (2008) 4.51
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med (2009) 4.05
The Fas signaling pathway: more than a paradigm. Science (2002) 3.45
Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic Biol Med (2008) 3.38
Fas-induced caspase denitrosylation. Science (1999) 3.21
S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide. Nat Med (2004) 3.15
The CD95 receptor: apoptosis revisited. Cell (2007) 3.13
Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system. Antioxid Redox Signal (2004) 3.04
Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis. J Exp Med (2004) 2.84
Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A (2006) 2.51
Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation. Antioxid Redox Signal (2005) 2.48
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis. J Clin Invest (1999) 2.43
The transcription factor NRF2 protects against pulmonary fibrosis. FASEB J (2004) 2.43
Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med (2005) 2.29
S-glutathiolation of Ras mediates redox-sensitive signaling by angiotensin II in vascular smooth muscle cells. J Biol Chem (2004) 2.09
Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding. Biochemistry (2001) 2.07
Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen. Am J Respir Cell Mol Biol (1997) 2.02
Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice. Am J Respir Cell Mol Biol (1997) 1.78
TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells. J Immunol (2002) 1.50
P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1996) 1.48
Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase. Free Radic Biol Med (2005) 1.44
Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity. Biochemistry (1998) 1.43
Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas. J Cell Biol (2009) 1.42
Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor. Am J Physiol Lung Cell Mol Physiol (2001) 1.42
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias. Eur Respir J (2003) 1.35
Aerosolized administration of N-acetylcysteine attenuates lung fibrosis induced by bleomycin in mice. Am J Respir Crit Care Med (2000) 1.33
Expression of Fas (CD95) and FasL (CD95L) in human airway epithelium. Am J Respir Cell Mol Biol (1998) 1.31
Targeted disruption of the glutaredoxin 1 gene does not sensitize adult mice to tissue injury induced by ischemia/reperfusion and hyperoxia. Free Radic Biol Med (2007) 1.25
Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol (2006) 1.25
Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo. Hum Pathol (2004) 1.19
Oxidant-induced S-glutathiolation inactivates protein kinase C-alpha (PKC-alpha): a potential mechanism of PKC isozyme regulation. Biochemistry (2000) 1.19
Glutathione-thiyl radical scavenging and transferase properties of human glutaredoxin (thioltransferase). Potential role in redox signal transduction. J Biol Chem (2003) 1.10
Epithelial cell apoptosis by fas ligand-positive myofibroblasts in lung fibrosis. Am J Respir Cell Mol Biol (2006) 1.01
Cellular and molecular targets of protein S-glutathiolation. Antioxid Redox Signal (2005) 1.01
Evasion of myofibroblasts from immune surveillance: a mechanism for tissue fibrosis. Proc Natl Acad Sci U S A (2007) 1.01
Oxygen-induced pulmonary injury in gamma-glutamyl transpeptidase-deficient mice. Lung (2001) 0.99
A classification scheme for redox-based modifications of proteins. Am J Respir Cell Mol Biol (2007) 0.91
The CD95 receptor: apoptosis revisited. Cell (2007) 3.13
Apoptosis regulators Fas and Bim cooperate in shutdown of chronic immune responses and prevention of autoimmunity. Immunity (2008) 2.62
Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A (2006) 2.51
Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation. Proc Natl Acad Sci U S A (2004) 2.19
Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. J Cell Biol (2006) 1.84
Redox-sensitive kinases of the nuclear factor-kappaB signaling pathway. Antioxid Redox Signal (2006) 1.67
Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1. J Cell Sci (2008) 1.60
Chronic heart failure reduces Akt phosphorylation in human skeletal muscle: relationship to muscle size and function. J Appl Physiol (1985) (2010) 1.59
Cellular FLIP (long form) regulates CD8+ T cell activation through caspase-8-dependent NF-kappa B activation. J Immunol (2005) 1.51
Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas. J Cell Biol (2009) 1.42
Morphological and cytochemical determination of cell death by apoptosis. Histochem Cell Biol (2007) 1.42
Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med (2014) 1.40
Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness. Am J Respir Crit Care Med (2008) 1.40
The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes. Mol Cell Biol (2002) 1.36
Nuclear factor kappaB, airway epithelium, and asthma: avenues for redox control. Proc Am Thorac Soc (2009) 1.31
Inhibition of apoptosis and caspase-3 in vascular smooth muscle cells by plasminogen activator inhibitor type-1. J Cell Biochem (2004) 1.31
In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization. Biochim Biophys Acta (2006) 1.27
c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis. Am J Respir Cell Mol Biol (2008) 1.26
Gammadelta T cells promote a Th1 response during coxsackievirus B3 infection in vivo: role of Fas and Fas ligand. J Virol (2002) 1.22
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxid Redox Signal (2006) 1.22
Augmentation of proliferation of vascular smooth muscle cells by plasminogen activator inhibitor type 1. Arterioscler Thromb Vasc Biol (2006) 1.15
Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection? Proc Am Thorac Soc (2009) 1.12
Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells. Proc Natl Acad Sci U S A (2007) 1.12
Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation. J Biol Chem (2007) 1.12
c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3. Am J Respir Cell Mol Biol (2010) 1.11
Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-β release in lung epithelial cells. Am J Respir Cell Mol Biol (2011) 1.11
Ablation of glutaredoxin-1 attenuates lipopolysaccharide-induced lung inflammation and alveolar macrophage activation. Am J Respir Cell Mol Biol (2010) 1.10
Cellular FLIP long form augments caspase activity and death of T cells through heterodimerization with and activation of caspase-8. J Immunol (2005) 1.01
Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates. J Immunol (2005) 1.01
Redox-based regulation of apoptosis: S-glutathionylation as a regulatory mechanism to control cell death. Antioxid Redox Signal (2011) 1.01
Lyme arthritis synovial gammadelta T cells instruct dendritic cells via fas ligand. J Immunol (2005) 1.00
Silica induces NLRP3 inflammasome activation in human lung epithelial cells. Part Fibre Toxicol (2013) 1.00
In situ detection and visualization of S-nitrosylated proteins following chemical derivatization: identification of Ran GTPase as a target for S-nitrosylation. Nitric Oxide (2004) 0.99
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells. Part Fibre Toxicol (2012) 0.98
The death receptor Fas (CD95/APO-1) mediates the deletion of T lymphocytes undergoing homeostatic proliferation. J Immunol (2005) 0.97
Oxidative processing of latent Fas in the endoplasmic reticulum controls the strength of apoptosis. Mol Cell Biol (2012) 0.97
High expression of Fas ligand by synovial fluid-derived gamma delta T cells in Lyme arthritis. J Immunol (2003) 0.96
Protocols for the detection of s-glutathionylated and s-nitrosylated proteins in situ. Methods Enzymol (2010) 0.96
Epithelial NF-κB orchestrates house dust mite-induced airway inflammation, hyperresponsiveness, and fibrotic remodeling. J Immunol (2013) 0.95
Proteolytic regulation of nuclear factor of activated T (NFAT) c2 cells and NFAT activity by caspase-3. J Biol Chem (2006) 0.94
In vivo levels of mitochondrial hydrogen peroxide increase with age in mtDNA mutator mice. Aging Cell (2014) 0.93
Distinct functions of airway epithelial nuclear factor-kappaB activity regulate nitrogen dioxide-induced acute lung injury. Am J Respir Cell Mol Biol (2009) 0.93
Cellular FLIP long form-transgenic mice manifest a Th2 cytokine bias and enhanced allergic airway inflammation. J Immunol (2004) 0.93
Strain-dependent activation of NF-kappaB in the airway epithelium and its role in allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol (2009) 0.92
In situ analysis of protein S-glutathionylation in lung tissue using glutaredoxin-1-catalyzed cysteine derivatization. Am J Pathol (2009) 0.92
Cooperation between classical and alternative NF-κB pathways regulates proinflammatory responses in epithelial cells. Am J Respir Cell Mol Biol (2012) 0.91
Nonphagocytic oxidase 1 causes death in lung epithelial cells via a TNF-RI-JNK signaling axis. Am J Respir Cell Mol Biol (2006) 0.91
Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling. Free Radic Biol Med (2011) 0.90
Reactive nitrogen species and cell signaling: implications for death or survival of lung epithelium. Am J Respir Crit Care Med (2002) 0.90
The c-FLIPL cleavage product p43FLIP promotes activation of extracellular signal-regulated kinase (ERK), nuclear factor κB (NF-κB), and caspase-8 and T cell survival. J Biol Chem (2013) 0.89
Interleukin-1 receptor and caspase-1 are required for the Th17 response in nitrogen dioxide-promoted allergic airway disease. Am J Respir Cell Mol Biol (2013) 0.88
Growth enhancement and food conversion efficiency of transgenic fish Labeo rohita. J Exp Zool A Comp Exp Biol (2004) 0.88
Plasma advanced glycation end-products and skin autofluorescence are increased in COPD. Eur Respir J (2013) 0.87
Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells. Exp Cell Res (2002) 0.87
Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics. Eur Respir J (2013) 0.87
Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD. Respir Res (2014) 0.87
c-FLIP(S) reduces activation of caspase and NF-kappaB pathways and decreases T cell survival. Eur J Immunol (2008) 0.86
Systemic inflammation and skeletal muscle dysfunction in chronic obstructive pulmonary disease: state of the art and novel insights in regulation of muscle plasticity. Clin Chest Med (2007) 0.86
Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation. Eur J Immunol (2010) 0.86
Activation of gamma delta T cells by Borrelia burgdorferi is indirect via a TLR- and caspase-dependent pathway. J Immunol (2008) 0.85
Genetic ablation of glutaredoxin-1 causes enhanced resolution of airways hyperresponsiveness and mucus metaplasia in mice with allergic airways disease. Am J Physiol Lung Cell Mol Physiol (2012) 0.85
Decreased plasma sRAGE levels in COPD: influence of oxygen therapy. Eur J Clin Invest (2012) 0.85
Induction of a mesenchymal expression program in lung epithelial cells by wingless protein (Wnt)/β-catenin requires the presence of c-Jun N-terminal kinase-1 (JNK1). Am J Respir Cell Mol Biol (2012) 0.83
Emerging mechanisms of glutathione-dependent chemistry in biology and disease. J Cell Biochem (2013) 0.83
Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation. Am J Physiol Lung Cell Mol Physiol (2014) 0.82
Interferon-β induces a long-lasting antiviral state in human respiratory epithelial cells. J Infect (2012) 0.82
The role of sex differences in autophagy in the heart during coxsackievirus B3-induced myocarditis. J Cardiovasc Transl Res (2013) 0.81
Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice. Free Radic Res (2012) 0.81
Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death. Am J Respir Cell Mol Biol (2011) 0.81
Catalase overexpression fails to attenuate allergic airways disease in the mouse. J Immunol (2007) 0.80
Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease. Inflamm Bowel Dis (2015) 0.80
Fas ligand deficiency impairs host inflammatory response against infection with the spirochete Borrelia burgdorferi. Infect Immun (2006) 0.80
Reduced immune response to Borrelia burgdorferi in the absence of γδ T cells. Infect Immun (2011) 0.80
Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease. Free Radic Res (2009) 0.80