Published in Biol Psychiatry on August 25, 2010
Personality and longevity: knowns, unknowns, and implications for public health and personalized medicine. J Aging Res (2011) 1.68
A genome-wide association study of depressive symptoms. Biol Psychiatry (2013) 1.58
A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus. Mol Psychiatry (2012) 1.55
Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci. Mol Psychiatry (2013) 1.16
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). PLoS One (2012) 1.14
Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia. Proc Natl Acad Sci U S A (2014) 1.14
Genetic analysis of cortical thickness and fractional anisotropy of water diffusion in the brain. Front Neurosci (2011) 1.09
Genetic determinants of depression: recent findings and future directions. Harv Rev Psychiatry (2015) 1.02
Resting glutamate levels and rapid glutamate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression. Neuropsychopharmacology (2011) 0.97
Genetic and clinical factors predict lithium's effects on PER2 gene expression rhythms in cells from bipolar disorder patients. Transl Psychiatry (2013) 0.97
Neuroticism, depressive symptoms, and serum BDNF. Psychosom Med (2011) 0.96
Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder. Transl Psychiatry (2012) 0.94
Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking. Transl Psychiatry (2011) 0.93
The sodium leak channel, NALCN, in health and disease. Front Cell Neurosci (2014) 0.90
Common variants on Xq28 conferring risk of schizophrenia in Han Chinese. Schizophr Bull (2013) 0.90
Associations between LSAMP gene polymorphisms and major depressive disorder and panic disorder. Transl Psychiatry (2012) 0.89
Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis. Psychol Med (2014) 0.89
Neurobiology, pathophysiology, and treatment of melatonin deficiency and dysfunction. ScientificWorldJournal (2012) 0.89
Personality traits prospectively predict verbal fluency in a lifespan sample. Psychol Aging (2011) 0.89
The retinoid-related orphan receptor alpha (RORA) gene and fear-related psychopathology. J Affect Disord (2013) 0.86
Heritability and molecular genetic basis of antisaccade eye tracking error rate: a genome-wide association study. Psychophysiology (2014) 0.84
Genetics of serum BDNF: meta-analysis of the Val66Met and genome-wide association study. World J Biol Psychiatry (2011) 0.83
Assessment of trait and state aspects of depression in schizophrenia. Schizophr Bull (2013) 0.83
Targeted pharmacogenetic analysis of antipsychotic response in the CATIE study. Pharmacogenomics (2012) 0.82
The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease. Front Synaptic Neurosci (2014) 0.81
RDoC and translational perspectives on the genetics of trauma-related psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet (2015) 0.80
Can single genes matter in a polygenic world? Biol Psychiatry (2010) 0.80
The role of rs2237781 within GRM8 in eating behavior. Brain Behav (2013) 0.79
Hostility in adolescents and adults: a genome-wide association study of the Young Finns. Transl Psychiatry (2011) 0.78
Associations of PER3 and RORA Circadian Gene Polymorphisms and Depressive Symptoms in Older Adults. Am J Geriatr Psychiatry (2015) 0.78
FMR1, circadian genes and depression: suggestive associations or false discovery? J Circadian Rhythms (2013) 0.78
GENOME-WIDE ASSOCIATION STUDY (GWAS) AND GENOME-WIDE BY ENVIRONMENT INTERACTION STUDY (GWEIS) OF DEPRESSIVE SYMPTOMS IN AFRICAN AMERICAN AND HISPANIC/LATINA WOMEN. Depress Anxiety (2016) 0.77
Genetic association of impulsivity in young adults: a multivariate study. Transl Psychiatry (2014) 0.77
Genome-wide linkage scan of antisocial behavior, depression, and impulsive substance use in the UCSF family alcoholism study. Psychiatr Genet (2012) 0.76
Association study of three single-nucleotide polymorphisms in the cyclic adenosine monophosphate response element binding 1 gene and major depressive disorder. Exp Ther Med (2015) 0.76
Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population. Neuropsychiatr Dis Treat (2015) 0.76
Constraints on Biological Mechanism from Disease Comorbidity Using Electronic Medical Records and Database of Genetic Variants. PLoS Comput Biol (2016) 0.75
RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response. Transl Psychiatry (2015) 0.75
CDH13 and HCRTR2 May Be Associated with Hypersomnia Symptom of Bipolar Depression: A Genome-Wide Functional Enrichment Pathway Analysis. Psychiatry Investig (2015) 0.75
Genome-Wide Association Study of Loneliness Demonstrates a Role for Common Variation. Neuropsychopharmacology (2016) 0.75
Neuroplasticity and second messenger pathways in antidepressant efficacy: pharmacogenetic results from a prospective trial investigating treatment resistance. Eur Arch Psychiatry Clin Neurosci (2017) 0.75
Cadherin-13 Deficiency Increases Dorsal Raphe 5-HT Neuron Density and Prefrontal Cortex Innervation in the Mouse Brain. Front Cell Neurosci (2017) 0.75
Pharmacogenetics of stimulant abuse liability: association of CDH13 variant with amphetamine response in a racially-heterogeneous sample of healthy young adults. Psychopharmacology (Berl) (2016) 0.75
Meta-analysis of genome-wide SNP- and pathway-based associations for facets of neuroticism. J Hum Genet (2017) 0.75
RORA Polymorphism Interacts with Childhood Maltreatment in Determining Anxiety Sensitivity by Sex: A Preliminary Study in Healthy Young Adults. Clin Psychopharmacol Neurosci (2017) 0.75
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet (2006) 115.71
Genomic control for association studies. Biometrics (1999) 64.39
Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry (2005) 58.92
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet (2006) 37.83
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature (2009) 33.26
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
The endophenotype concept in psychiatry: etymology and strategic intentions. Am J Psychiatry (2003) 21.70
Genotype imputation. Annu Rev Genomics Hum Genet (2009) 18.64
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Evidence-based health policy--lessons from the Global Burden of Disease Study. Science (1996) 13.50
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity (2007) 13.29
Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis. JAMA (2009) 12.35
Family-based association tests for genomewide association scans. Am J Hum Genet (2007) 10.67
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet (2008) 10.49
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet (2006) 8.19
Molecular components of the mammalian circadian clock. Hum Mol Genet (2006) 7.51
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
In silico method for inferring genotypes in pedigrees. Nat Genet (2006) 7.08
Epigenetic regulation in psychiatric disorders. Nat Rev Neurosci (2007) 6.00
A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron (2004) 5.71
Gender differences in personality traits across cultures: robust and surprising findings. J Pers Soc Psychol (2001) 4.92
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov (2008) 4.46
Personality and major depression: a Swedish longitudinal, population-based twin study. Arch Gen Psychiatry (2006) 3.94
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
Universal features of personality traits from the observer's perspective: data from 50 cultures. J Pers Soc Psychol (2005) 3.70
Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. Mol Psychiatry (2008) 3.68
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry (2009) 3.59
Cadherin regulates dendritic spine morphogenesis. Neuron (2002) 3.55
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
A longitudinal twin study of personality and major depression in women. Arch Gen Psychiatry (1993) 2.97
Circadian genes, rhythms and the biology of mood disorders. Pharmacol Ther (2007) 2.62
Disruption of the nuclear hormone receptor RORalpha in staggerer mice. Nature (1996) 2.58
Hierarchical linear modeling analyses of the NEO-PI-R scales in the Baltimore Longitudinal Study of Aging. Psychol Aging (2005) 2.56
Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J Pharmacol Exp Ther (2001) 2.55
Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. Am J Med Genet B Neuropsychiatr Genet (2008) 2.53
Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease. Neurochem Int (2004) 2.47
A whole genome association study of neuroticism using DNA pooling. Mol Psychiatry (2007) 2.30
Genome-wide association scan for five major dimensions of personality. Mol Psychiatry (2008) 2.29
Five-Factor Model personality profiles of drug users. BMC Psychiatry (2008) 2.11
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Mol Psychiatry (2009) 2.03
Neuroticism, major depression and gender: a population-based twin study. Psychol Med (2002) 2.01
Personality plasticity after age 30. Pers Soc Psychol Bull (2006) 1.97
Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet (2009) 1.92
Heritability of facet-level traits in a cross-cultural twin sample: support for a hierarchical model of personality. J Pers Soc Psychol (1998) 1.91
Molecular studies of major depressive disorder: the epigenetic perspective. Mol Psychiatry (2007) 1.88
Genome-wide association study of smoking initiation and current smoking. Am J Hum Genet (2009) 1.87
Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism. Arch Gen Psychiatry (2008) 1.75
Genome-wide association for methamphetamine dependence: convergent results from 2 samples. Arch Gen Psychiatry (2008) 1.72
Expression of T-cadherin (CDH13, H-Cadherin) in human brain and its characteristics as a negative growth regulator of epidermal growth factor in neuroblastoma cells. J Neurochem (2000) 1.64
The cadherin superfamily in neural development: diversity, function and interaction with other molecules. Front Biosci (2003) 1.56
Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology (2010) 1.56
Personality self-reports are concurrently reliable and valid during acute depressive episodes. J Affect Disord (2005) 1.55
A developmental genetic analysis of adult personality: extraversion and neuroticism from 18 to 59 years of age. J Pers Soc Psychol (1994) 1.46
Temporally distinct demands for classic cadherins in synapse formation and maturation. Mol Cell Neurosci (2004) 1.42
The Italian version of the NEO PI-R: Conceptual and empirical support for the use of targeted rotation. Pers Individ Dif (2003) 1.40
Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Eur J Hum Genet (2009) 1.38
Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. Eur J Neurosci (2003) 1.36
Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG. Eur J Pharmacol (2005) 1.24
Immunohistochemical characterization of the orphan nuclear receptor ROR alpha in the mouse nervous system. J Histochem Cytochem (2004) 1.14
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2009) 1.12
PER2 variantion is associated with depression vulnerability. Am J Med Genet B Neuropsychiatr Genet (2010) 1.03
Personality traits in Sardinia: testing founder population effects on trait means and variances. Behav Genet (2006) 1.02
Relationship between the five-factor model of personality and unipolar, bipolar and schizophrenic patients. Psychiatry Res (1997) 1.01
Intra-individual Change in Personality Stability and Age. J Res Pers (2010) 0.98
Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats. Neuropharmacology (2004) 0.95
Therapeutic potential of group III metabotropic glutamate receptors. Curr Med Chem (2008) 0.94
Positive associations of polymorphisms in the metabotropic glutamate receptor type 8 gene (GRM8) with schizophrenia. Am J Med Genet B Neuropsychiatr Genet (2004) 0.94
The group III mGlu receptor agonist ACPT-I exerts anxiolytic-like but not antidepressant-like effects, mediated by the serotonergic and GABA-ergic systems. Neuropharmacology (2009) 0.85
Identification of human cadherin-14, a novel neurally specific type II cadherin, by protein interaction cloning. J Biol Chem (1997) 0.85
A map of human genome variation from population-scale sequencing. Nature (2010) 121.13
A second generation human haplotype map of over 3.1 million SNPs. Nature (2007) 85.39
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science (2007) 43.16
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet (2008) 30.94
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol (2010) 26.41
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics (2010) 21.21
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Genotype imputation. Annu Rev Genomics Hum Genet (2009) 18.64
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet (2006) 17.36
Genome-wide detection and characterization of positive selection in human populations. Nature (2007) 17.27
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Gait speed and survival in older adults. JAMA (2011) 15.01
Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet (2007) 14.99
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature (2007) 14.43
LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics (2010) 13.54
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
A global reference for human genetic variation. Nature (2015) 12.85
Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci (2004) 12.46
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet (2012) 11.29
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet (2009) 9.45
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Meta-analysis and imputation refines the association of 15q25 with smoking quantity. Nat Genet (2010) 8.55
Heritability of cardiovascular and personality traits in 6,148 Sardinians. PLoS Genet (2006) 8.19
Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci (2006) 8.00
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31