Published in Science on November 01, 1996
Homeopathic Treatment for Depression in Peri- and Postmenopausal Women (HOMDEP-MENOP) | NCT01635218
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature (2007) 144.95
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
Criteria for evaluating evidence on public health interventions. J Epidemiol Community Health (2002) 8.16
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Global burden of oral conditions in 1990-2010: a systematic analysis. J Dent Res (2013) 6.15
Using internet and mobile phone technology to deliver an automated physical activity program: randomized controlled trial. J Med Internet Res (2007) 5.79
Cognition and depression: current status and future directions. Annu Rev Clin Psychol (2010) 4.88
Measuring the burden of neglected tropical diseases: the global burden of disease framework. PLoS Negl Trop Dis (2007) 4.87
Analysis of the lung microbiome in the "healthy" smoker and in COPD. PLoS One (2011) 4.65
Cross-national epidemiology of DSM-IV major depressive episode. BMC Med (2011) 4.52
Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nat Rev Drug Discov (2008) 4.46
Monitoring global health: time for new solutions. BMJ (2004) 4.39
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry (2008) 3.85
Lung infection--a public health priority. PLoS Med (2006) 3.34
Modeling the impact of global tuberculosis control strategies. Proc Natl Acad Sci U S A (1998) 3.22
Emergence of a new norovirus genotype II.4 variant associated with global outbreaks of gastroenteritis. J Clin Microbiol (2006) 2.97
Hypertension treatment and control in sub-Saharan Africa: the epidemiological basis for policy. BMJ (1998) 2.93
Global burden of severe periodontitis in 1990-2010: a systematic review and meta-regression. J Dent Res (2014) 2.66
The epidemiology of depression across cultures. Annu Rev Public Health (2013) 2.60
Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. Am J Hum Genet (2006) 2.55
Sexual mixing patterns in the spread of gonococcal and chlamydial infections. Am J Public Health (1999) 2.54
The burden of human African trypanosomiasis. PLoS Negl Trop Dis (2008) 2.53
Improvement in household stoves and risk of chronic obstructive pulmonary disease in Xuanwei, China: retrospective cohort study. BMJ (2005) 2.36
Treatment of suicidal people around the world. Br J Psychiatry (2011) 2.34
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. BMC Med Genet (2007) 2.00
Evaluation and outcome measures in the treatment of female urinary stress incontinence: International Urogynecological Association (IUGA) guidelines for research and clinical practice. Int Urogynecol J Pelvic Floor Dysfunct (2007) 1.95
Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease. Thorax (1999) 1.93
Effect of simulated commercial flight on oxygenation in patients with interstitial lung disease and chronic obstructive pulmonary disease. Thorax (2004) 1.85
Elevated left and reduced right orbitomedial prefrontal fractional anisotropy in adults with bipolar disorder revealed by tract-based spatial statistics. Arch Gen Psychiatry (2008) 1.83
The health impact of polyparasitism in humans: are we under-estimating the burden of parasitic diseases? Parasitology (2008) 1.82
Abnormal amygdala-prefrontal effective connectivity to happy faces differentiates bipolar from major depression. Biol Psychiatry (2009) 1.78
The costs of depression. Psychiatr Clin North Am (2011) 1.77
Hyperpolarized 3He diffusion MRI and histology in pulmonary emphysema. Magn Reson Med (2006) 1.76
Assessing available information on the burden of sepsis: global estimates of incidence, prevalence and mortality. J Glob Health (2012) 1.74
Elevated striatal and decreased dorsolateral prefrontal cortical activity in response to emotional stimuli in euthymic bipolar disorder: no associations with psychotropic medication load. Bipolar Disord (2008) 1.71
Clinically important changes in health-related quality of life for patients with chronic obstructive pulmonary disease: an expert consensus panel report. J Gen Intern Med (2003) 1.70
Physiological and radiological characterisation of patients diagnosed with chronic obstructive pulmonary disease in primary care. Thorax (2000) 1.65
Excess heart-disease-related mortality in a national study of patients with mental disorders: identifying modifiable risk factors. Gen Hosp Psychiatry (2009) 1.65
Genome-wide association scan of trait depression. Biol Psychiatry (2010) 1.65
Activities of new fluoroquinolones against fluoroquinolone-resistant pathogens of the lower respiratory tract. Antimicrob Agents Chemother (1998) 1.62
New disability weights for the global burden of disease. Bull World Health Organ (2010) 1.59
New concepts in the pathobiology of chronic obstructive pulmonary disease. Proc Am Thorac Soc (2008) 1.59
Use of the Internet for health information by the chronically ill. Prev Chronic Dis (2004) 1.56
First nationwide survey on cardiovascular risk factors in Grand-Duchy of Luxembourg (ORISCAV-LUX). BMC Public Health (2010) 1.50
N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD. Respir Res (2009) 1.50
A role for white matter abnormalities in the pathophysiology of bipolar disorder. Neurosci Biobehav Rev (2009) 1.49
The Benefits of Exercise for the Clinically Depressed. Prim Care Companion J Clin Psychiatry (2004) 1.48
A step forward for understanding the morbidity burden in Guinea: a national descriptive study. BMC Public Health (2011) 1.47
International Study to Predict Optimized Treatment for Depression (iSPOT-D), a randomized clinical trial: rationale and protocol. Trials (2011) 1.46
Circulating vascular cell adhesion molecule-1 is associated with cerebral blood flow dysregulation, mobility impairment, and falls in older adults. Hypertension (2015) 1.45
Improving the public health utility of global cardiovascular mortality data: the rise of ischemic heart disease. Popul Health Metr (2011) 1.43
Evaluating the WHO Assessment Instrument for Mental Health Systems by comparing mental health policies in four countries. Bull World Health Organ (2008) 1.42
Glutamatergic modulators: the future of treating mood disorders? Harv Rev Psychiatry (2010) 1.42
Prospective associations of insomnia markers and symptoms with depression. Am J Epidemiol (2010) 1.40
Antenatal syphilis screening using point-of-care testing in Sub-Saharan African countries: a cost-effectiveness analysis. PLoS Med (2013) 1.39
Adolescent smoking and depression: evidence for self-medication and peer smoking mediation. Addiction (2009) 1.39
Abnormal left and right amygdala-orbitofrontal cortical functional connectivity to emotional faces: state versus trait vulnerability markers of depression in bipolar disorder. Biol Psychiatry (2010) 1.37
Cognitive and symptomatic predictors of functional disability in schizophrenia. Schizophr Res (2010) 1.35
Chronic obstructive pulmonary disease (COPD) and occupational exposures. J Occup Med Toxicol (2006) 1.33
COPD in India: Iceberg or volcano? J Thorac Dis (2012) 1.30
Predisposition locus for major depression at chromosome 12q22-12q23.2. Am J Hum Genet (2003) 1.29
Assessing the global burden of ischemic heart disease, part 2: analytic methods and estimates of the global epidemiology of ischemic heart disease in 2010. Glob Heart (2012) 1.26
The evolution of the Global Burden of Disease framework for disease, injury and risk factor quantification: developing the evidence base for national, regional and global public health action. Global Health (2005) 1.25
The uneven tides of the health transition. Soc Sci Med (2002) 1.25
Novel glutamatergic agents for major depressive disorder and bipolar disorder. Pharmacol Biochem Behav (2011) 1.24
Metabolic syndrome in South Asians. Indian J Endocrinol Metab (2012) 1.24
Protecting children from environmental toxins. PLoS Med (2005) 1.23
Global Burden of Severe Tooth Loss: A Systematic Review and Meta-analysis. J Dent Res (2014) 1.21
Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes. Int J Chron Obstruct Pulmon Dis (2009) 1.19
Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats. Biol Psychiatry (2013) 1.19
Exponential enhancement of oncolytic vesicular stomatitis virus potency by vector-mediated suppression of inflammatory responses in vivo. Mol Ther (2007) 1.19
Use of lambda-mu-sigma-derived Z score for evaluating respiratory impairment in middle-aged persons. Respir Care (2011) 1.18
Antiherpes virus-specific treatment and cognition in schizophrenia: a test-of-concept randomized double-blind placebo-controlled trial. Schizophr Bull (2012) 1.17
Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date. Drugs (2012) 1.17
Impaired sensorimotor gating in unmedicated adults with obsessive-compulsive disorder. Neuropsychopharmacology (2012) 1.17
Enhanced oncolytic potency of vesicular stomatitis virus through vector-mediated inhibition of NK and NKT cells. Cancer Gene Ther (2008) 1.17
Self-management education for patients with chronic obstructive pulmonary disease: a systematic review. Thorax (2003) 1.17
Insomnia and sleep duration as mediators of the relationship between depression and hypertension incidence. Am J Hypertens (2009) 1.17
Gender differences in the risk of coronary artery disease in iran. Iran J Public Health (2012) 1.17
Metabolic syndrome and cardiovascular disease in South Asians. Vasc Health Risk Manag (2009) 1.16
Perceived need for treatment for alcohol use disorders: results from two national surveys. Psychiatr Serv (2009) 1.16
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J Clin Invest (2009) 1.16
Transcripts involved in calcium signaling and telencephalic neuronal fate are altered in induced pluripotent stem cells from bipolar disorder patients. Transl Psychiatry (2014) 1.15
The role of the tripartite glutamatergic synapse in the pathophysiology and therapeutics of mood disorders. Neuroscientist (2009) 1.13
Religiosity and decreased risk of substance use disorders: is the effect mediated by social support or mental health status? Soc Psychiatry Psychiatr Epidemiol (2009) 1.13
Multivariate permutation analysis associates multiple polymorphisms with subphenotypes of major depression. Genes Brain Behav (2007) 1.12
The effects of physical exercise in schizophrenia and affective disorders. Eur Arch Psychiatry Clin Neurosci (2013) 1.11
Quality of care for cardiovascular disease-related conditions in patients with and without mental disorders. J Gen Intern Med (2008) 1.10
Comorbidity and disease burden in the National Comorbidity Survey Replication (NCS-R). Depress Anxiety (2012) 1.09
Disseminating self-help: positive psychology exercises in an online trial. J Med Internet Res (2012) 1.09
Equity in private insurance coverage for substance abuse: a perspective on parity. Health Aff (Millwood) (2007) 1.09
Admissions to hospital with exacerbations of chronic obstructive pulmonary disease: Effect of age related factors and service organisation. Thorax (2006) 1.08
Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders. Curr Pharm Des (2009) 1.08
Comparison of the prevalence of chronic obstructive pulmonary disease diagnosed by lower limit of normal and fixed ratio criteria. J Korean Med Sci (2009) 1.07
Physical activity inversely associated with the presence of depression among urban adolescents in regional China. BMC Public Health (2009) 1.07
Echocardiographic evaluation of heart in chronic obstructive pulmonary disease patient and its co-relation with the severity of disease. Lung India (2011) 1.06
Perceived need for care among low-income immigrant and U.S.-born black and Latina women with depression. J Womens Health (Larchmt) (2009) 1.05
An exploration of attitudes among black Americans towards psychiatric genetic research. Psychiatry (2009) 1.05
Pharmacogenetics studies in STAR*D: strengths, limitations, and results. Psychiatr Serv (2009) 1.04
Respiratory infection and the impact of pulmonary immunity on lung health and disease. Am J Respir Crit Care Med (2012) 1.04
Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet (1997) 44.03
Mortality by cause for eight regions of the world: Global Burden of Disease Study. Lancet (1997) 29.18
Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet (1997) 25.40
Mortality from tobacco in developed countries: indirect estimation from national vital statistics. Lancet (1992) 25.28
Alcohol consumption and mortality among middle-aged and elderly U.S. adults. N Engl J Med (1997) 8.25
Mortality from smoking worldwide. Br Med Bull (1996) 7.87
Regional patterns of disability-free life expectancy and disability-adjusted life expectancy: global Burden of Disease Study. Lancet (1997) 7.29
The global burden of disease in 1990: summary results, sensitivity analysis and future directions. Bull World Health Organ (1994) 6.99
The global burden of disease, 1990-2020. Nat Med (1998) 6.50
Quantifying disability: data, methods and results. Bull World Health Organ (1994) 4.99
Measuring the accumulated hazards of smoking: global and regional estimates for 2000. Tob Control (2003) 4.94
Armed conflict as a public health problem. BMJ (2002) 4.42
Healthy life expectancy in 191 countries, 1999. Lancet (2001) 4.31
On the comparable quantification of health risks: lessons from the Global Burden of Disease Study. Epidemiology (1999) 3.66
The decline in child mortality: a reappraisal. Bull World Health Organ (2000) 3.46
Global and regional cause-of-death patterns in 1990. Bull World Health Organ (1994) 3.37
Progress and directions in refining the global burden of disease approach: a response to Williams. Health Econ (2000) 3.17
The use of cause-of-death statistics for health situation assessment: national and international experiences. World Health Stat Q (1990) 2.84
The utility of DALYs for public health policy and research: a reply. Bull World Health Organ (1997) 2.49
Regional, disease specific patterns of smoking-attributable mortality in 2000. Tob Control (2004) 2.12
Measuring the burden of disease. Lancet (1998) 1.58
At least one in seven cases of cancer is caused by smoking. Global estimates for 1985. Int J Cancer (1994) 1.45
Hypertension in developing countries. World Health Stat Q (1988) 1.45
Sustained proliferation of PDX-1+ cells derived from human islets. Diabetes (1999) 1.35
Ex vivo expansion of human pancreatic endocrine cells. J Clin Endocrinol Metab (1997) 1.33
Tobacco or health. World Health Stat Q (1993) 1.32
KSA antigen Ep-CAM mediates cell-cell adhesion of pancreatic epithelial cells: morphoregulatory roles in pancreatic islet development. J Cell Biol (1998) 1.26
Global and regional mortality patterns by cause of death in 1980. Int J Epidemiol (1986) 1.22
Global gene expression profiling and histochemical analysis of the developing human fetal pancreas. Diabetologia (2007) 1.21
An in vivo model for study of the angiogenic effects of basic fibroblast growth factor. Biochem Biophys Res Commun (1987) 1.19
Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro. J Endocrinol (2000) 1.18
Counting the dead in China. Measuring tobacco's impact in the developing world. BMJ (1998) 1.14
Growth factor/matrix-induced proliferation of human adult beta-cells. Diabetes (1995) 1.13
The incremental effect of age-weighting on YLLs, YLDs, and DALYs: a response. Bull World Health Organ (1996) 1.09
Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells. Diabetes (1994) 1.08
On the assessment of maternal mortality. World Health Stat Q (1987) 1.04
A role for activin A and betacellulin in human fetal pancreatic cell differentiation and growth. J Clin Endocrinol Metab (2000) 1.03
Trehalose: a cryoprotectant that enhances recovery and preserves function of human pancreatic islets after long-term storage. Diabetes (1997) 1.02
Sex differentials in mortality. WHO Chron (1984) 1.02
Functional beta-cell mass after transplantation of human fetal pancreatic cells: differentiation or proliferation? Diabetes (1997) 1.00
Reducing child mortality. Bull World Health Organ (2000) 0.94
Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas. Cell Transplant (1997) 0.92
Epidemiologic surveillance of the tobacco epidemic. MMWR Morb Mortal Wkly Rep (1992) 0.91
Keratinocyte growth factor and beta-cell differentiation in human fetal pancreatic endocrine precursor cells. Diabetologia (2003) 0.89
Gene transfer to human pancreatic endocrine cells using viral vectors. Diabetes (1999) 0.88
Developmental gene expression in the human fetal pancreas. Pediatr Res (1994) 0.86
Decrease in the number of neonatal islets required for successful transplantation by strict metabolic control of diabetic rats. Transplantation (1988) 0.85
Smoking and death in Russia. Tob Control (1998) 0.84
Factors influencing islet transplantation. Number, location, and metabolic control. Transplantation (1990) 0.83
A note on estimating the cause of death structure in high mortality populations. Popul Bull UN (1982) 0.83
Protection from cell death in cultured human fetal pancreatic cells. Cell Transplant (2000) 0.81
The use of digital image processing to quantitate angiogenesis induced by basic fibroblast growth factor and transplanted pancreatic islets. Microvasc Res (1991) 0.81
Tuberculosis mortality differentials in Indonesia during 2007-2008: evidence for health policy and monitoring. Int J Tuberc Lung Dis (2011) 0.80
Transplantation of human fetal pancreas: fresh vs. cultured fetal islets or ICCS. J Mol Med (Berl) (1999) 0.80
Enhancement of pancreatic islet cell monolayer growth by endothelial cell matrix and insulin. In Vitro Cell Dev Biol (1989) 0.79
100 years of mortality due to chronic obstructive pulmonary disease in Australia: the role of tobacco consumption. Int J Tuberc Lung Dis (2012) 0.79
Development of a cell line from the human fetal pancreas. Transplant Proc (1995) 0.78
Maturation and function of human fetal pancreatic cells after cryopreservation. Transplantation (1993) 0.78
Analysis of a human fetal pancreatic islet cell line. Transplant Proc (1997) 0.78
International trends in cancer mortality in France, West Germany, Italy, Japan, England and Wales, and the United States. Ann N Y Acad Sci (1990) 0.77
Health for all: analyzing health status and determinants. World Health Stat Q (1998) 0.77
Use of hepatocyte growth factor/scatter factor to increase transplantable human fetal islet cell mass. Transplant Proc (1994) 0.77
Angiogenic peptides in pancreatic islet transplantation to diabetic rats. Transplantation (1990) 0.76
In vivo maturation and growth potential of human fetal pancreases: fresh versus cultured tissue. Transplant Proc (1995) 0.76
Investigating Australia's burden of disease. Med J Aust (2000) 0.75
Changing grassroots perception on the family. Rural Reconstr Forum (1995) 0.75
Using national mortality data to study the changing sex differential in mortality. Soz Praventivmed (1984) 0.75
Mortality patterns and trends among the elderly in developed countries. World Health Stat Q (1982) 0.75
Generation of viable isletlike cell clusters from cryopreserved human fetal pancreas. Transplant Proc (1992) 0.75
The impact of demographic trends on health: introduction. World Health Stat Q (1987) 0.75
Health projections. Introduction. World Health Stat Q (1984) 0.75
[Preventable deaths: general view]. World Health Stat Q (1989) 0.75
Health outlook for South and East Asia for the year 2000. World Health Stat Q (1981) 0.75