Published in Drug Metab Dispos on September 17, 2010
Discovery of a sesamin-metabolizing microorganism and a new enzyme. Proc Natl Acad Sci U S A (2016) 0.82
Influence of sesamin on CYP2C-mediated diclofenac metabolism: in vitro and in vivo analysis. Pharmacol Res Perspect (2015) 0.77
Human hepatic metabolism of the anti-osteoporosis drug eldecalcitol involves sterol C4-methyl oxidase. Pharmacol Res Perspect (2015) 0.75
Common origin of methylenedioxy ring degradation and demethylation in bacteria. Sci Rep (2017) 0.75
Effect of health foods on cytochrome P450-mediated drug metabolism. J Pharm Health Care Sci (2017) 0.75
Upregulation of CREB-mediated transcription enhances both short- and long-term memory. J Neurosci (2011) 1.41
Aryl hydrocarbon receptor suppresses intestinal carcinogenesis in ApcMin/+ mice with natural ligands. Proc Natl Acad Sci U S A (2009) 1.40
Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers. Drug Metab Dispos (2009) 1.34
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. Mol Pharmacol (2005) 1.33
Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells. J Biol Chem (2003) 1.21
Crystal structure of CYP105A1 (P450SU-1) in complex with 1alpha,25-dihydroxyvitamin D3. Biochemistry (2008) 1.08
Effectiveness of aquatic exercise and balneotherapy: a summary of systematic reviews based on randomized controlled trials of water immersion therapies. J Epidemiol (2009) 1.07
Metabolism of vitamin D by human microsomal CYP2R1. Biochem Biophys Res Commun (2004) 1.06
Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker. Am J Physiol Regul Integr Comp Physiol (2006) 1.05
1,25-(OH)2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of Nephrolithiasis. Clin J Am Soc Nephrol (2013) 1.04
The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. Toxicol Sci (2009) 1.03
The roles of cytochrome P450 enzymes in prostate cancer development and treatment. Anticancer Res (2012) 1.01
A systematic review of nonrandomized controlled trials on the curative effects of aquatic exercise. Int J Gen Med (2011) 0.97
Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation. Arch Toxicol (2011) 0.94
Identification of the amino acid residue of CYP27B1 responsible for binding of 25-hydroxyvitamin D3 whose mutation causes vitamin D-dependent rickets type 1. J Biol Chem (2005) 0.93
Insight into functional diversity of cytochrome P450 in the white-rot basidiomycete Phanerochaete chrysosporium: involvement of versatile monooxygenase. Biochem Biophys Res Commun (2011) 0.92
Effects of coexpression of UGT1A9 on enzymatic activities of human UGT1A isoforms. Drug Metab Dispos (2007) 0.92
Evaluation of 19-nor-2alpha-(3-hydroxypropyl)-1alpha,25-dihydroxyvitamin D3 as a therapeutic agent for androgen-dependent prostate cancer. Anticancer Res (2009) 0.91
A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats. Toxicol Sci (2004) 0.90
Human cytochrome P450-dependent differential metabolism among three 2α-substituted-1α,25-dihydroxyvitamin D(3) analogs. J Steroid Biochem Mol Biol (2012) 0.89
Structure-function analysis of vitamin D 24-hydroxylase (CYP24A1) by site-directed mutagenesis: amino acid residues responsible for species-based difference of CYP24A1 between humans and rats. Mol Pharmacol (2006) 0.89
Novel metabolism of 1 alpha,25-dihydroxyvitamin D3 with C24-C25 bond cleavage catalyzed by human CYP24A1. Biochemistry (2004) 0.88
Hepatic UDP-glucuronosyltransferases responsible for glucuronidation of thyroxine in humans. Drug Metab Dispos (2007) 0.87
Interactions between human UDP-glucuronosyltransferase (UGT) 2B7 and UGT1A enzymes. J Pharm Sci (2010) 0.87
Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells. J Steroid Biochem Mol Biol (2011) 0.86
Interaction between mitochondrial CYP27B1 and adrenodoxin: role of arginine 458 of mouse CYP27B1. Biochemistry (2006) 0.86
CYP24A1 as a potential target for cancer therapy. Anticancer Agents Med Chem (2014) 0.86
Purification and characterization of mouse CYP27B1 overproduced by an Escherichia coli system coexpressing molecular chaperonins GroEL/ES. Biochem Biophys Res Commun (2004) 0.85
Conversion of vitamin D3 to 1alpha,25-dihydroxyvitamin D3 by Streptomyces griseolus cytochrome P450SU-1. Biochem Biophys Res Commun (2004) 0.85
Metabolism of A-ring diastereomers of 1alpha,25-dihydroxyvitamin D3 by CYP24A1. Biochem Biophys Res Commun (2004) 0.84
Metabolism of mono- and dichloro-dibenzo-p-dioxins by Phanerochaete chrysosporium cytochromes P450. Appl Microbiol Biotechnol (2010) 0.84
Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1. Biochemistry (2008) 0.84
Cholecystokinin-A receptors regulate photic input pathways to the circadian clock. FASEB J (2007) 0.84
Influence of royal jelly on mouse hepatic gene expression and safety assessment with a DNA microarray. J Nutr Sci Vitaminol (Tokyo) (2005) 0.83
Metabolism of 1alpha,25-dihydroxyvitamin D2 by human CYP24A1. Biochem Biophys Res Commun (2009) 0.83
Upregulation of Myo6 expression after traumatic stress in mouse hippocampus. Neurosci Lett (2008) 0.83
Isolation of a new phlorotannin, a potent inhibitor of carbohydrate-hydrolyzing enzymes, from the brown alga Sargassum patens. J Agric Food Chem (2012) 0.82
Functional analyses of cytochrome P450 genes responsible for the early steps of brassicicene C biosynthesis. Bioorg Med Chem Lett (2009) 0.82
Synthesis and evaluation of geometric analogs of 1α,25-dihydroxyvitamin D2 as potential therapeutics. J Steroid Biochem Mol Biol (2015) 0.82
Enzymatic properties of cytochrome P450 catalyzing 3'-hydroxylation of naringenin from the white-rot fungus Phanerochaete chrysosporium. Biochem Biophys Res Commun (2009) 0.82
The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells. Drug Metab Pharmacokinet (2012) 0.81
Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1: enzymes and catalysis. FEBS J (2010) 0.81
Mechanism of the anti-proliferative action of 25-hydroxy-19-nor-vitamin D(3) in human prostate cells. J Mol Endocrinol (2011) 0.81
A hypopharyngeal gland protein of the worker honeybee Apis mellifera L. enhances proliferation of primary-cultured rat hepatocytes and suppresses apoptosis in the absence of serum. Protein Expr Purif (2005) 0.81
Enzymatic properties of human CYP2W1 expressed in Escherichia coli. Biochem Biophys Res Commun (2006) 0.81
Structural basis of species differences between human and experimental animal CYP1A1s in metabolism of 3,3',4,4',5-pentachlorobiphenyl. J Biochem (2011) 0.81
Development of a synchronous enzyme-reaction system for a highly sensitive enzyme immunoassay. J Biochem (2002) 0.80
The impact of pharmacogenetics of metabolic enzymes and transporters on the pharmacokinetics of telmisartan in healthy volunteers. Pharmacogenet Genomics (2011) 0.80
Role of Gln 85 of human CYP27A1 in 25-hydroxyvitamin D(3)-binding and protein folding. Biochem Biophys Res Commun (2007) 0.80
Anti-proliferative activity of 25-hydroxyvitamin D3 in human prostate cells. Mol Cell Endocrinol (2013) 0.80
A novel mechanism for polychlorinated biphenyl-induced decrease in serum thyroxine level in rats. Drug Metab Dispos (2007) 0.80
Avian cytochrome P450 (CYP) 1-3 family genes: isoforms, evolutionary relationships, and mRNA expression in chicken liver. PLoS One (2013) 0.80
Metabolic pathways of dioxin by CYP1A1: species difference between rat and human CYP1A subfamily in the metabolism of dioxins. Arch Biochem Biophys (2003) 0.80
Human UDP-glucuronosyltransferase expression in insect cells: ratio of active to inactive recombinant proteins and the effects of a C-terminal his-tag on glucuronidation kinetics. Drug Metab Dispos (2012) 0.80
How is sesamin metabolised in the human liver to show its biological effects? Expert Opin Drug Metab Toxicol (2011) 0.79
Biodegradation of polychlorinated dibenzo-p-dioxins by recombinant yeast expressing rat CYP1A subfamily. Arch Biochem Biophys (2002) 0.79
Rat cytochrome P450-mediated transformation of dichlorodibenzo-p-dioxins by recombinant white-rot basidiomycete Coriolus hirsutus. Appl Microbiol Biotechnol (2005) 0.79
Metabolism of 2 alpha-propoxy-1 alpha,25-dihydroxyvitamin D3 and 2 alpha-(3-hydroxypropoxy)-1 alpha,25-dihydroxyvitamin D3 by human CYP27A1 and CYP24A1. Drug Metab Dispos (2005) 0.79
Potent 19-norvitamin D analogs for prostate and liver cancer therapy. Future Med Chem (2012) 0.79
Homology modeling of human 25-hydroxyvitamin D3 1alpha-hydroxylase (CYP27B1) based on the crystal structure of rabbit CYP2C5. J Steroid Biochem Mol Biol (2004) 0.79
Can rotational thromboelastometry predict septic disseminated intravascular coagulation? Blood Coagul Fibrinolysis (2015) 0.79