Substitution at carbon 2 of 19-nor-1α,25-dihydroxyvitamin D3 with 3-hydroxypropyl group generates an analogue with enhanced chemotherapeutic potency in PC-3 prostate cancer cells.

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Published in J Steroid Biochem Mol Biol on September 03, 2011

Authors

Diego Iglesias-Gato1, Shasha Zheng, John N Flanagan, Lan Jiang, Atsushi Kittaka, Toshiyuki Sakaki, Keiko Yamamoto, Toshimasa Itoh, Nathan K Lebrasseur, Gunnar Norstedt, Tai C Chen

Author Affiliations

1: Department of Molecular Medicine and Surgery, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.

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