Published in Genes Cancer on June 01, 2010
MYC on the path to cancer. Cell (2012) 8.65
c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells. Cell (2012) 6.49
Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting. Mol Cell (2013) 2.83
c-Myc and cancer metabolism. Clin Cancer Res (2012) 1.60
Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. PLoS One (2014) 1.57
MYC, Metabolism, and Cancer. Cancer Discov (2015) 1.29
Targeting MYC Expression through G-Quadruplexes. Genes Cancer (2010) 1.29
The circadian clock in cancer development and therapy. Prog Mol Biol Transl Sci (2013) 1.28
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony. Genes Cancer (2010) 1.11
Amplitude modulation of androgen signaling by c-MYC. Genes Dev (2013) 1.08
c-Myc induction of programmed cell death may contribute to carcinogenesis: a perspective inspired by several concepts of chemical carcinogenesis. Cancer Biol Ther (2011) 1.04
Cellular MYCro economics: Balancing MYC function with MYC expression. Cold Spring Harb Perspect Med (2013) 0.95
Theoretical analysis of competing conformational transitions in superhelical DNA. PLoS Comput Biol (2012) 0.89
Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway. Genes Cancer (2012) 0.85
Cytoplasmic calcium increase via fusion with inactivated Sendai virus induces apoptosis in human multiple myeloma cells by downregulation of c-Myc oncogene. Oncotarget (2016) 0.78
Genetic systems to investigate regulation of oncogenes and tumour suppressor genes in Drosophila. Cells (2012) 0.77
Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models. Nat Commun (2015) 0.77
Partition of Myc into immobile vs. mobile complexes within nuclei. Sci Rep (2013) 0.77
SerpinB3 and Yap Interplay Increases Myc Oncogenic Activity. Sci Rep (2015) 0.76
Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth. Nucleic Acids Res (2016) 0.75
Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells. Front Cell Dev Biol (2017) 0.75
Evidence for an oncogenic modifier role for mutant histone acetyltransferases in diffuse large B-cell lymphoma. Leuk Lymphoma (2016) 0.75
KSR1 and EPHB4 Regulate Myc and PGC1β To Promote Survival of Human Colon Tumors. Mol Cell Biol (2016) 0.75
Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling. Genes (Basel) (2017) 0.75
Small molecule selectively suppresses MYC transcription in cancer cells. Proc Natl Acad Sci U S A (2017) 0.75
MYC Modulation around the CDK2/p27/SKP2 Axis. Genes (Basel) (2017) 0.75
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Stochastic gene expression in a single cell. Science (2002) 34.54
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
Supercoiling of the DNA template during transcription. Proc Natl Acad Sci U S A (1987) 14.25
c-Myc regulates transcriptional pause release. Cell (2010) 11.64
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A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci U S A (2003) 7.30
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs. Nature (2009) 6.88
Variability in gene expression underlies incomplete penetrance. Nature (2010) 5.85
An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol Cell Biol (1996) 5.74
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling. Nat Genet (2009) 5.65
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MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res (2007) 5.25
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HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev (2009) 4.41
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Drosophila myc regulates organ size by inducing cell competition. Cell (2004) 3.98
The functional response of upstream DNA to dynamic supercoiling in vivo. Nat Struct Mol Biol (2008) 3.90
dMyc transforms cells into super-competitors. Cell (2004) 3.66
Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells. Mol Cell Biol (2010) 2.80
Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. EMBO J (2007) 2.75
Myc recruits P-TEFb to mediate the final step in the transcriptional activation of the cad promoter. J Biol Chem (2002) 2.68
Timeline: Z-DNA: the long road to biological function. Nat Rev Genet (2003) 2.65
The life cycle of C-myc: from synthesis to degradation. Cell Cycle (2004) 2.56
Long-range enhancers on 8q24 regulate c-Myc. Proc Natl Acad Sci U S A (2010) 2.54
c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism. J Biol Chem (2001) 2.36
The c-myc promoter: still MysterY and challenge. Adv Cancer Res (2008) 2.06
Reduced c-Myc signaling triggers telomere-independent senescence by regulating Bmi-1 and p16(INK4a). Proc Natl Acad Sci U S A (2006) 2.06
Making myc. Curr Top Microbiol Immunol (2006) 1.87
Transcription of human c-myc in permeabilized nuclei is associated with formation of Z-DNA in three discrete regions of the gene. EMBO J (1992) 1.75
The dynamic response of upstream DNA to transcription-generated torsional stress. Nat Struct Mol Biol (2004) 1.74
The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expression. EMBO J (2006) 1.73
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein. J Biol Chem (2009) 1.72
The role of supercoiling in transcriptional control of MYC and its importance in molecular therapeutics. Nat Rev Cancer (2009) 1.71
c-Myc is required for the formation of intestinal crypts but dispensable for homeostasis of the adult intestinal epithelium. Mol Cell Biol (2005) 1.70
Energetics of the strand separation transition in superhelical DNA. J Mol Biol (1992) 1.53
A genome-wide screen for beta-catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol (2008) 1.42
c-myc expression: keep the noise down! Mol Cells (2005) 1.37
A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Proc Natl Acad Sci U S A (2009) 1.37
Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of Drosophila Myc. Proc Natl Acad Sci U S A (2007) 1.37
Supercoil-driven DNA structures regulate genetic transactions. Front Biosci (2007) 1.35
Translational activation of the non-AUG-initiated c-myc 1 protein at high cell densities due to methionine deprivation. Genes Dev (1992) 1.35
Loss of protooncogene c-Myc function impedes G1 phase progression both before and after the restriction point. Mol Biol Cell (2003) 1.34
MYC activation associated with the integration of HPV DNA at the MYC locus in genital tumors. Oncogene (2006) 1.31
The c-MYC NHE III(1): function and regulation. Annu Rev Pharmacol Toxicol (2010) 1.31
Energetics at the DNA supercoiling transition. Biophys J (2010) 1.29
TFIIH operates through an expanded proximal promoter to fine-tune c-myc expression. Mol Cell Biol (2005) 1.23
Gene regulation and epigenetic remodeling in murine embryonic stem cells by c-Myc. PLoS One (2009) 1.20
Conditional deletion of c-myc does not impair liver regeneration. Cancer Res (2006) 1.19
NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III(1). Mol Cancer Ther (2009) 1.19
Targeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression. PLoS One (2009) 1.05
Control of wing size and proportions by Drosophila myc. Genetics (2009) 1.02
The zinc-finger protein CNBP is required for forebrain formation in the mouse. Development (2003) 1.00
Hierarchical mechanisms build the DNA-binding specificity of FUSE binding protein. Proc Natl Acad Sci U S A (2008) 0.98
Cellular nucleic-acid-binding protein, a transcriptional enhancer of c-Myc, promotes the formation of parallel G-quadruplexes. Biochem J (2010) 0.96
Effects of IL-3 on promoter usage, attenuation and antisense transcription of the c-myc oncogene in the IL-3-dependent Ba/F3 early pre-B cell line. Oncogene (1991) 0.90
Identification of processes that influence negative supercoiling in the human c-myc gene. Biochim Biophys Acta (1997) 0.90
Deciphering the genome's regulatory code: the many languages of DNA. Bioessays (2010) 0.85
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