Published in Nat Genet on June 28, 2009
A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol (2011) 16.53
MYC on the path to cancer. Cell (2012) 8.65
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
Next-generation genomics: an integrative approach. Nat Rev Genet (2010) 5.88
Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion. Nat Genet (2011) 5.67
MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res (2009) 4.32
Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat Genet (2009) 3.94
The many faces and functions of β-catenin. EMBO J (2012) 3.85
Long non-coding RNAs and cancer: a new frontier of translational research? Oncogene (2012) 3.83
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Res (2010) 3.46
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC. Proc Natl Acad Sci U S A (2010) 3.37
Interpreting noncoding genetic variation in complex traits and human disease. Nat Biotechnol (2012) 3.01
Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proc Natl Acad Sci U S A (2013) 2.93
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression. Nat Genet (2012) 2.86
Upregulation of c-MYC in cis through a large chromatin loop linked to a cancer risk-associated single-nucleotide polymorphism in colorectal cancer cells. Mol Cell Biol (2010) 2.80
Beyond GWASs: illuminating the dark road from association to function. Am J Hum Genet (2013) 2.67
CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer. Genome Res (2013) 2.57
Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk. Nat Genet (2010) 2.45
An 8q24 gene desert variant associated with prostate cancer risk confers differential in vivo activity to a MYC enhancer. Genome Res (2010) 2.24
Current status of genome-wide association studies in cancer. Hum Genet (2011) 2.14
Architecture of inherited susceptibility to common cancer. Nat Rev Cancer (2010) 2.14
A compendium of genome-wide associations for cancer: critical synopsis and reappraisal. J Natl Cancer Inst (2010) 2.00
Molecular pathological epidemiology of epigenetics: emerging integrative science to analyze environment, host, and disease. Mod Pathol (2013) 1.95
The molecular pathology of cancer. Nat Rev Clin Oncol (2010) 1.86
The Glanville fritillary genome retains an ancient karyotype and reveals selective chromosomal fusions in Lepidoptera. Nat Commun (2014) 1.85
Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus. Cell Res (2014) 1.83
Identification of {beta}-catenin binding regions in colon cancer cells using ChIP-Seq. Nucleic Acids Res (2010) 1.81
A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3). Nat Genet (2010) 1.78
A polymorphism in IRF4 affects human pigmentation through a tyrosinase-dependent MITF/TFAP2A pathway. Cell (2013) 1.75
Genome-wide association studies and beyond. Annu Rev Public Health (2010) 1.73
Cancer susceptibility variants and the risk of adult glioma in a US case-control study. J Neurooncol (2011) 1.69
Genomic approaches towards finding cis-regulatory modules in animals. Nat Rev Genet (2012) 1.65
Aspirin use, 8q24 single nucleotide polymorphism rs6983267, and colorectal cancer according to CTNNB1 alterations. J Natl Cancer Inst (2013) 1.63
A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression. PLoS Genet (2011) 1.60
Transcriptional enhancers in development and disease. Genome Biol (2012) 1.52
Genome-wide association analyses identify three new susceptibility loci for primary angle closure glaucoma. Nat Genet (2012) 1.51
Enhancer-targeted genome editing selectively blocks innate resistance to oncokinase inhibition. Genome Res (2014) 1.49
CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations. Oncotarget (2013) 1.48
Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". PLoS Genet (2010) 1.47
VDR/RXR and TCF4/β-catenin cistromes in colonic cells of colorectal tumor origin: impact on c-FOS and c-MYC gene expression. Mol Endocrinol (2011) 1.46
Genome-wide association studies of cancer. J Clin Oncol (2010) 1.45
Thyroid cancer susceptibility polymorphisms: confirmation of loci on chromosomes 9q22 and 14q13, validation of a recessive 8q24 locus and failure to replicate a locus on 5q24. J Med Genet (2012) 1.44
Maps of open chromatin guide the functional follow-up of genome-wide association signals: application to hematological traits. PLoS Genet (2011) 1.41
Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis. PLoS Genet (2010) 1.40
Long-range interaction and correlation between MYC enhancer and oncogenic long noncoding RNA CARLo-5. Proc Natl Acad Sci U S A (2014) 1.39
Genome-wide association studies in cancer--current and future directions. Carcinogenesis (2009) 1.39
Generalizability and epidemiologic characterization of eleven colorectal cancer GWAS hits in multiple populations. Cancer Epidemiol Biomarkers Prev (2010) 1.38
A beta-catenin/TCF-coordinated chromatin loop at MYC integrates 5' and 3' Wnt responsive enhancers. Proc Natl Acad Sci U S A (2009) 1.37
Integrative functional genomics identifies an enhancer looping to the SOX9 gene disrupted by the 17q24.3 prostate cancer risk locus. Genome Res (2012) 1.35
Positive regulation of c-Myc by cohesin is direct, and evolutionarily conserved. Dev Biol (2010) 1.34
Integrative genomic analysis implicates gain of PIK3CA at 3q26 and MYC at 8q24 in chronic lymphocytic leukemia. Clin Cancer Res (2012) 1.33
Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes. Hum Mol Genet (2011) 1.33
TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proc Natl Acad Sci U S A (2010) 1.32
Genetic heterogeneity in colorectal cancer associations between African and European americans. Gastroenterology (2010) 1.31
MYC, Metabolism, and Cancer. Cancer Discov (2015) 1.29
Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a cis-acting regulator of EIF3H. PLoS Genet (2010) 1.29
The 8q24 gene desert: an oasis of non-coding transcriptional activity. Front Genet (2012) 1.28
Replication study of SNP associations for colorectal cancer in Hong Kong Chinese. Br J Cancer (2010) 1.24
Junk DNA and the long non-coding RNA twist in cancer genetics. Oncogene (2015) 1.22
Characterization of the association between 8q24 and colon cancer: gene-environment exploration and meta-analysis. BMC Cancer (2010) 1.22
You Don't Muck with MYC. Genes Cancer (2010) 1.20
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci. Nat Commun (2015) 1.19
GWAS3D: Detecting human regulatory variants by integrative analysis of genome-wide associations, chromosome interactions and histone modifications. Nucleic Acids Res (2013) 1.18
Allele-specific expression of TGFBR1 in colon cancer patients. Carcinogenesis (2010) 1.17
Genome-wide mechanisms of nuclear receptor action. Trends Endocrinol Metab (2009) 1.16
GWAS-identified colorectal cancer susceptibility loci associated with clinical outcomes. Carcinogenesis (2012) 1.16
Genome-wide epigenetic data facilitate understanding of disease susceptibility association studies. J Biol Chem (2012) 1.15
Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proc Natl Acad Sci U S A (2014) 1.15
Layers of epistasis: genome-wide regulatory networks and network approaches to genome-wide association studies. Wiley Interdiscip Rev Syst Biol Med (2010) 1.15
HBS1L-MYB intergenic variants modulate fetal hemoglobin via long-range MYB enhancers. J Clin Invest (2014) 1.14
Genetic polymorphisms in pre-microRNA genes as prognostic markers of colorectal cancer. Cancer Epidemiol Biomarkers Prev (2011) 1.14
Recent insights into the pathogenesis of colorectal cancer. Curr Opin Gastroenterol (2010) 1.13
Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level. Genome Biol (2010) 1.12
Maps of open chromatin highlight cell type-restricted patterns of regulatory sequence variation at hematological trait loci. Genome Res (2013) 1.10
Laying a solid foundation for Manhattan--'setting the functional basis for the post-GWAS era'. Trends Genet (2014) 1.10
Polymorphisms near TBX5 and GDF7 are associated with increased risk for Barrett's esophagus. Gastroenterology (2014) 1.08
Chromosome 8q24-Associated Cancers and MYC. Genes Cancer (2010) 1.07
No effect of cancer-associated SNP rs6983267 in the 8q24 region on co-expression of MYC and TCF7L2 in normal colon tissue. Mol Cancer (2009) 1.06
NOTCH2 in breast cancer: association of SNP rs11249433 with gene expression in ER-positive breast tumors without TP53 mutations. Mol Cancer (2010) 1.06
Functional interpretation of non-coding sequence variation: concepts and challenges. Bioessays (2013) 1.06
Multiple Wnt/ß-catenin responsive enhancers align with the MYC promoter through long-range chromatin loops. PLoS One (2011) 1.05
EPMA position paper in cancer: current overview and future perspectives. EPMA J (2015) 1.04
MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 methyltransferase. Cancer Res (2012) 1.04
Low-penetrance susceptibility variants in familial colorectal cancer. Cancer Epidemiol Biomarkers Prev (2010) 1.01
Pesticide use modifies the association between genetic variants on chromosome 8q24 and prostate cancer. Cancer Res (2010) 1.00
Pancreatic cancer susceptibility loci and their role in survival. PLoS One (2011) 0.98
Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese. Am J Hum Genet (2012) 0.98
Genetic architecture of colorectal cancer. Gut (2015) 0.97
Molecular pathways: aspirin and Wnt signaling-a molecularly targeted approach to cancer prevention and treatment. Clin Cancer Res (2014) 0.96
Prostate cancer risk locus at 8q24 as a regulatory hub by physical interactions with multiple genomic loci across the genome. Hum Mol Genet (2014) 0.96
COGENT (COlorectal cancer GENeTics) revisited. Mutagenesis (2012) 0.96
A systematic approach to understand the functional consequences of non-protein coding risk regions. Cell Cycle (2010) 0.96
Human genetics and genomics a decade after the release of the draft sequence of the human genome. Hum Genomics (2011) 0.95
MCS9.7 enhancer activity is highly, but not completely, associated with expression of Irf6 and p63. Dev Dyn (2011) 0.95
Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus. PLoS Genet (2013) 0.95
Modulation of enhancer looping and differential gene targeting by Epstein-Barr virus transcription factors directs cellular reprogramming. PLoS Pathog (2013) 0.95
Cellular MYCro economics: Balancing MYC function with MYC expression. Cold Spring Harb Perspect Med (2013) 0.95
Identifying potential cancer driver genes by genomic data integration. Sci Rep (2013) 0.95
8q24 Cancer risk allele associated with major metastatic risk in inflammatory breast cancer. PLoS One (2012) 0.94
Dissecting the causal genetic mechanisms of coronary heart disease. Curr Atheroscler Rep (2014) 0.93
Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics (2004) 125.23
The International HapMap Project. Nature (2003) 73.65
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat Methods (2007) 45.04
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet (2007) 32.41
Identification of c-MYC as a target of the APC pathway. Science (1998) 24.25
The significance of digital gene expression profiles. Genome Res (1997) 23.90
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma. Science (1997) 22.80
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data. Nucleic Acids Res (2005) 17.58
Cumulative association of five genetic variants with prostate cancer. N Engl J Med (2008) 15.34
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet (2007) 11.62
Linking colorectal cancer to Wnt signaling. Cell (2000) 11.58
Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet (2007) 9.88
Diversity and complexity in DNA recognition by transcription factors. Science (2009) 9.07
Incidence of hereditary nonpolyposis colorectal cancer and the feasibility of molecular screening for the disease. N Engl J Med (1998) 8.47
A common genetic risk factor for colorectal and prostate cancer. Nat Genet (2007) 7.11
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet (2009) 6.99
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Genome-wide analysis of transcript isoform variation in humans. Nat Genet (2008) 6.70
Sequence variant on 8q24 confers susceptibility to urinary bladder cancer. Nat Genet (2008) 6.69
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell (2006) 6.49
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet (2007) 6.02
Modelling Myc inhibition as a cancer therapy. Nature (2008) 5.81
Myc deletion rescues Apc deficiency in the small intestine. Nature (2007) 5.42
Genome-wide association. Closing the net on common disease genes. Science (2007) 4.89
Patched acts catalytically to suppress the activity of Smoothened. Nature (2002) 4.69
The Intestinal Wnt/TCF Signature. Gastroenterology (2006) 4.48
Requirement for beta-catenin in anterior-posterior axis formation in mice. J Cell Biol (2000) 4.36
Population-based molecular detection of hereditary nonpolyposis colorectal cancer. J Clin Oncol (2000) 3.98
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet (2007) 3.93
Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen. Cell (1993) 3.46
Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development. Cell (2002) 3.37
Genome-wide association studies in cancer. Hum Mol Genet (2008) 3.34
Comprehensive resequence analysis of a 136 kb region of human chromosome 8q24 associated with prostate and colon cancers. Hum Genet (2008) 2.41
Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge. Genes Dev (2003) 2.34
Genetic variation in 8q24 associated with risk of colorectal cancer. Cancer Biol Ther (2007) 2.32
Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Development (1998) 2.29
Variants on 9p24 and 8q24 are associated with risk of colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res (2007) 2.02
Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk. Hum Mol Genet (2008) 1.96
Beta-catenin signaling is required for neural differentiation of embryonic stem cells. Development (2004) 1.92
Serial analysis of chromatin occupancy identifies beta-catenin target genes in colorectal carcinoma cells. Proc Natl Acad Sci U S A (2007) 1.89
Wnt signaling inhibitors regulate the transcriptional response to morphogenetic Shh-Gli signaling in the neural tube. Dev Cell (2006) 1.65
Allelic imbalance at rs6983267 suggests selection of the risk allele in somatic colorectal tumor evolution. Cancer Res (2008) 1.59
Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis. Oncogene (2006) 1.43
A common 8q24 variant and the risk of colon cancer: a population-based case-control study. Cancer Epidemiol Biomarkers Prev (2008) 1.42
Wnt signaling as a therapeutic target for cancer. Methods Mol Biol (2007) 1.34
High-throughput assay for determining specificity and affinity of protein-DNA binding interactions. Nat Protoc (2006) 1.34
Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer (2009) 1.25
Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene. Nucleic Acids Res (2007) 1.14
Locating potential enhancer elements by comparative genomics using the EEL software. Nat Protoc (2006) 1.13
Functional analysis of cis-regulatory elements controlling initiation and maintenance of early Cdx1 gene expression in the mouse. Dev Dyn (2002) 0.95
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. Nat Genet (2008) 16.17
Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls. Nature (2010) 12.27
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet (2007) 11.62
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened. Genes Dev (2002) 8.56
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat Genet (2002) 8.19
Genome-wide association study identifies five susceptibility loci for glioma. Nat Genet (2009) 7.62
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol (2003) 7.42
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet (2008) 6.97
Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial. Lancet (2011) 6.77
Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nat Genet (2008) 6.75
Small molecule modulation of Smoothened activity. Proc Natl Acad Sci U S A (2002) 6.55
Medulloblastoma growth inhibition by hedgehog pathway blockade. Science (2002) 6.53
Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell (2006) 6.49
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet (2008) 6.26
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. Nat Genet (2012) 6.25
A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet (2007) 6.02
Minimizing the risk of reporting false positives in large-scale RNAi screens. Nat Methods (2006) 5.96
Hedgehog: functions and mechanisms. Genes Dev (2008) 5.69
Common 5p15.33 and 6p21.33 variants influence lung cancer risk. Nat Genet (2008) 5.43
A global map of human gene expression. Nat Biotechnol (2010) 5.32
DNA-binding specificities of human transcription factors. Cell (2013) 5.14
A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell (2012) 4.89
Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. N Engl J Med (2003) 4.88
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo. EMBO J (2010) 4.78
A recurrent mutation in PALB2 in Finnish cancer families. Nature (2007) 4.64
Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet (2010) 4.51
Loci on 7p12.2, 10q21.2 and 14q11.2 are associated with risk of childhood acute lymphoblastic leukemia. Nat Genet (2009) 4.47
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia. Nat Genet (2008) 4.37
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs. Nat Med (2011) 4.25
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33. Nat Genet (2010) 4.20
Counting absolute numbers of molecules using unique molecular identifiers. Nat Methods (2011) 4.18
The EUROclass trial: defining subgroups in common variable immunodeficiency. Blood (2007) 4.14
Genetic prognostic and predictive markers in colorectal cancer. Nat Rev Cancer (2009) 3.99
Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk. Nat Genet (2007) 3.93
Retracted A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function. Nat Genet (2009) 3.88
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet (2010) 3.86
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Frequency and spectrum of cancers in the Peutz-Jeghers syndrome. Clin Cancer Res (2006) 3.81
Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. N Engl J Med (2008) 3.76
Identification of pathways regulating cell size and cell-cycle progression by RNAi. Nature (2006) 3.60
Diagnostic criteria for monoclonal B-cell lymphocytosis. Br J Haematol (2005) 3.50
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities. Genome Res (2010) 3.46
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer. Nat Genet (2011) 3.37
Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat Genet (2012) 3.31
Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet (2012) 3.19
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas. Science (2011) 3.17
Mutations in PTF1A cause pancreatic and cerebellar agenesis. Nat Genet (2004) 3.09
Metastasis-Associated Gene Expression Changes Predict Poor Outcomes in Patients with Dukes Stage B and C Colorectal Cancer. Clin Cancer Res (2009) 3.08
Mutations in BRIP1 confer high risk of ovarian cancer. Nat Genet (2011) 3.06
Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. J Natl Cancer Inst (2011) 3.05
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites. Cell (2013) 2.98
Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis. J Clin Oncol (2004) 2.95
The risk of extra-colonic, extra-endometrial cancer in the Lynch syndrome. Int J Cancer (2008) 2.95
Low-level microsatellite instability in most colorectal carcinomas. Cancer Res (2002) 2.87
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts. Gut (2013) 2.86