Martin Steinhoff

Author PubWeight™ 104.93‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The neurobiology of itch. Nat Rev Neurosci 2006 3.25
2 IL-31: a new link between T cells and pruritus in atopic skin inflammation. J Allergy Clin Immunol 2006 2.39
3 Neuronal control of skin function: the skin as a neuroimmunoendocrine organ. Physiol Rev 2006 2.30
4 Role for protease activity in visceral pain in irritable bowel syndrome. J Clin Invest 2007 2.09
5 Cytokines and chemokines orchestrate atopic skin inflammation. J Allergy Clin Immunol 2006 2.08
6 Frontiers in pruritus research: scratching the brain for more effective itch therapy. J Clin Invest 2006 1.90
7 The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia. Sci Signal 2011 1.75
8 Evaluation of protease-activated receptor 2 in murine models of arthritis. Arthritis Rheum 2007 1.70
9 "Outside-to-inside" (and now back to "outside") pathogenic mechanisms in atopic dermatitis. J Invest Dermatol 2008 1.64
10 Tumor immune escape by the loss of homeostatic chemokine expression. Proc Natl Acad Sci U S A 2007 1.58
11 Expression of vanilloid receptor subtype 1 in cutaneous sensory nerve fibers, mast cells, and epithelial cells of appendage structures. Exp Dermatol 2004 1.52
12 Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor. Am J Physiol Cell Physiol 2011 1.51
13 Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. Cancer Res 2006 1.42
14 Endosomal endothelin-converting enzyme-1: a regulator of beta-arrestin-dependent ERK signaling. J Biol Chem 2009 1.27
15 The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest 2013 1.27
16 UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proc Natl Acad Sci U S A 2013 1.26
17 Activation of proteinase-activated receptor-2 by human kallikrein-related peptidases. J Invest Dermatol 2007 1.25
18 Proinflammatory role of proteinase-activated receptor-2 in humans and mice during cutaneous inflammation in vivo. FASEB J 2003 1.22
19 Endothelin-converting enzyme 1 degrades neuropeptides in endosomes to control receptor recycling. Proc Natl Acad Sci U S A 2007 1.21
20 Pathophysiology of pruritus in atopic dermatitis: an overview. Exp Dermatol 2002 1.21
21 Post-endocytic sorting of calcitonin receptor-like receptor and receptor activity-modifying protein 1. J Biol Chem 2007 1.21
22 Endothelin-converting enzyme-1 regulates endosomal sorting of calcitonin receptor-like receptor and beta-arrestins. J Cell Biol 2007 1.20
23 Colitis induced by proteinase-activated receptor-2 agonists is mediated by a neurogenic mechanism. Can J Physiol Pharmacol 2003 1.17
24 Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B. J Invest Dermatol 2005 1.16
25 Retracted A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest 2004 1.15
26 Efficacy and safety of once-daily topical brimonidine tartrate gel 0.5% for the treatment of moderate to severe facial erythema of rosacea: results of two randomized, double-blind, and vehicle-controlled pivotal studies. J Drugs Dermatol 2013 1.14
27 Agonists of proteinase-activated receptor 2 induce cytokine release and activation of nuclear transcription factor kappaB in human dermal microvascular endothelial cells. J Invest Dermatol 2002 1.12
28 Neurophysiology of pruritus: cutaneous elicitation of itch. Arch Dermatol 2003 1.12
29 Ubiquitin-dependent down-regulation of the neurokinin-1 receptor. J Biol Chem 2006 1.12
30 Neurovascular and neuroimmune aspects in the pathophysiology of rosacea. J Investig Dermatol Symp Proc 2011 1.10
31 Characterization of thrombin-induced leukocyte rolling and adherence: a potential proinflammatory role for proteinase-activated receptor-4. J Immunol 2002 1.10
32 Neuronal sensitization for histamine-induced itch in lesional skin of patients with atopic dermatitis. Arch Dermatol 2003 1.09
33 PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin. Nat Commun 2011 1.09
34 Proteinase-activated receptor-2 in the skin: receptor expression, activation and function during health and disease. Drug News Perspect 2008 1.08
35 Recycling and resensitization of the neurokinin 1 receptor. Influence of agonist concentration and Rab GTPases. J Biol Chem 2004 1.07
36 Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection. Am J Pathol 2006 1.07
37 Proteinase-activated receptors: novel signals for peripheral nerves. Trends Neurosci 2003 1.06
38 Successful treatment of generalized eruptive histiocytoma with PUVA. J Dtsch Dermatol Ges 2007 1.05
39 IL-33: a novel danger signal system in atopic dermatitis. J Invest Dermatol 2012 1.05
40 Mouse model of touch-evoked itch (alloknesis). J Invest Dermatol 2012 1.04
41 Neurophysiology of pruritus: interaction of itch and pain. Arch Dermatol 2003 1.03
42 Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosacea. J Invest Dermatol 2011 1.02
43 Endothelin-converting enzyme-1 degrades internalized somatostatin-14. Endocrinology 2008 1.01
44 Par2 inactivation inhibits early production of TSLP, but not cutaneous inflammation, in Netherton syndrome adult mouse model. J Invest Dermatol 2010 0.98
45 Pruritus in elderly patients--eruptions of senescence. Semin Cutan Med Surg 2011 0.98
46 Neuroimmune interactions in allergic skin diseases. Curr Opin Allergy Clin Immunol 2007 0.97
47 Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies. J Drugs Dermatol 2014 0.96
48 Agonists of proteinase-activated receptor-2 affect transendothelial migration and apoptosis of human neutrophils. Exp Dermatol 2007 0.95
49 Functional characterization and expression analysis of the proteinase-activated receptor-2 in human cutaneous mast cells. J Invest Dermatol 2006 0.94
50 Microfluidic reveals generation of platelet-strings on tumor-activated endothelium. Thromb Haemost 2007 0.92
51 Role of matriptase and proteinase-activated receptor-2 in nonmelanoma skin cancer. J Invest Dermatol 2009 0.90
52 Role of protease-activated receptors in human skin fibrosis and scleroderma. Exp Dermatol 2011 0.90
53 Anatomy and neurophysiology of pruritus. Semin Cutan Med Surg 2011 0.89
54 Management of itch in atopic dermatitis. Semin Cutan Med Surg 2011 0.89
55 Agonists of proteinase-activated receptor-2 enhance IFN-gamma-inducible effects on human monocytes: role in influenza A infection. J Immunol 2008 0.89
56 Proteinase-activated receptor-1 is an anti-inflammatory signal for colitis mediated by a type 2 immune response. Inflamm Bowel Dis 2005 0.89
57 Intermedin: a skin peptide that is downregulated in atopic dermatitis. J Invest Dermatol 2006 0.88
58 Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones. J Physiol 2011 0.88
59 Proteinase-activated receptor-2 (PAR2): a tumor suppressor in skin carcinogenesis. J Invest Dermatol 2007 0.88
60 Rosacea: The cytokine and chemokine network. J Investig Dermatol Symp Proc 2011 0.87
61 Transient receptor potential ankyrin 1 mediates chronic pancreatitis pain in mice. Am J Physiol Gastrointest Liver Physiol 2013 0.87
62 Improvement in facial erythema within 30 minutes of initial application of brimonidine tartrate in patients with rosacea. J Drugs Dermatol 2014 0.87
63 Role of spinal neurotransmitter receptors in itch: new insights into therapies and drug development. CNS Neurosci Ther 2010 0.86
64 Pruritus and renal failure. Semin Cutan Med Surg 2011 0.86
65 Psychoneuroimmunology of psychological stress and atopic dermatitis: pathophysiologic and therapeutic updates. Acta Derm Venereol 2012 0.86
66 Long-term safety of ivermectin 1% cream vs azelaic acid 15% gel in treating inflammatory lesions of rosacea: results of two 40-week controlled, investigator-blinded trials. J Drugs Dermatol 2014 0.86
67 Innovative management of pruritus. Dermatol Clin 2010 0.85
68 PAR-2 inhibition reverses experimental pulmonary hypertension. Circ Res 2012 0.85
69 Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1-induced pruritus. J Clin Invest 2014 0.84
70 Serine protease inhibition reduces post-ischemic granulocyte recruitment in mouse intestine. Am J Pathol 2011 0.84
71 Thrombin receptor: An endogenous inhibitor of inflammatory pain, activating opioid pathways. Pain 2009 0.84
72 Localization of mu-opioid receptor 1A on sensory nerve fibers in human skin. Regul Pept 2002 0.84
73 Agonist-induced endocytosis of rat somatostatin receptor 1. Endocrinology 2006 0.83
74 Histamine and antihistamines in atopic dermatitis. Adv Exp Med Biol 2010 0.83
75 Calcineurin inhibitors for the treatment of atopic dermatitis. Expert Opin Pharmacother 2008 0.83
76 Neurogenic components of trypsin- and thrombin-induced inflammation in rat skin, in vivo. Exp Dermatol 2006 0.83
77 Contribution of bone marrow-derived cells to the pro-inflammatory effects of protease-activated receptor-2 in colitis. Inflamm Res 2010 0.82
78 Serum kallikrein-8 correlates with skin activity, but not psoriatic arthritis, in patients with psoriatic disease. Clin Chem Lab Med 2013 0.82
79 Rosacea and small intestinal bacterial overgrowth: prevalence and response to rifaximin. J Am Acad Dermatol 2013 0.82
80 Preliminary evidence for a role of mast cells in epidermal growth factor receptor inhibitor-induced pruritus. J Am Acad Dermatol 2010 0.81
81 Livedoid vasculopathy in a pediatric patient with elevated lipoprotein(a) levels: prompt response to continuous low-molecular-weight heparin. Arch Dermatol 2010 0.81
82 Role of proteinase-activated receptor-2 in anti-bacterial and immunomodulatory effects of interferon-γ on human neutrophils and monocytes. Immunology 2011 0.81
83 Pituitary adenylate cyclase activating polypeptide: an important vascular regulator in human skin in vivo. Am J Pathol 2010 0.81
84 New tools for assessing the individual risk of metastasis in renal cell carcinoma. Clin Exp Metastasis 2012 0.81
85 Neurogenic rosacea: a distinct clinical subtype requiring a modified approach to treatment. Arch Dermatol 2011 0.81
86 A role for proteinase-activated receptor-1 in inflammatory bowel diseases. J Clin Invest 2006 0.80
87 Pathway management in ambulatory wound care: defining local standards for quality improvement and interprofessional care. Int Wound J 2005 0.79
88 Recapitulating atopic dermatitis in three dimensions: cross talk between keratinocytes and nerve fibers. J Invest Dermatol 2013 0.79
89 Role of cytokines and chemokines in itch. Handb Exp Pharmacol 2015 0.79
90 Proteinase-activated receptors 1 and 2 regulate invasive behavior of human melanoma cells via activation of protein kinase D1. J Invest Dermatol 2011 0.79
91 Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage. FASEB J 2004 0.78
92 α-1-Antitrypsin and IFN-γ reduce the severity of IC-mediated vasculitis by regulation of leukocyte recruitment in vivo. J Invest Dermatol 2012 0.78
93 Anti-inflammatory effects of nitric oxide-releasing hydrocortisone NCX 1022, in a murine model of contact dermatitis. Br J Pharmacol 2004 0.78
94 Intracellular degradation of somatostatin-14 following somatostatin-receptor3-mediated endocytosis in rat insulinoma cells. FEBS J 2008 0.77
95 Pruritus/itch: the science and treatment. Introduction. Semin Cutan Med Surg 2011 0.76
96 Erythema leprosum--after treatment of Lepromatous Leprosy. J Dtsch Dermatol Ges 2009 0.76
97 Interferon-γ induces upregulation and activation of the interleukin-31 receptor in human dermal microvascular endothelial cells. Exp Dermatol 2010 0.76
98 Disseminated erosive pustular dermatosis also involving the mucosa: successful treatment with oral dapsone. Acta Derm Venereol 2012 0.75
99 Proteinase-activated receptor-2 agonist activates anti-influenza mechanisms and modulates IFNγ-induced antiviral pathways in human neutrophils. Biomed Res Int 2013 0.75
100 [Persistent plaque on the back and right upper arm. Latent syphilis (lues III) with tubero-ulcero-serpiginous plaque]. J Dtsch Dermatol Ges 2006 0.75
101 [Atopic dermatitis. Pathophysiologic background, scientific status quo and therapeutic strategies]. Med Monatsschr Pharm 2005 0.75