PubRank

Ihor R Lemischka

Author PubWeight™ 103.34‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A stem cell molecular signature. Science 2002 14.47
2 Dissecting self-renewal in stem cells with RNA interference. Nature 2006 11.66
3 Stem cells and their niches. Science 2006 7.86
4 The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat Neurosci 2006 4.49
5 Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010 4.38
6 Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell 2011 4.04
7 shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell 2007 3.40
8 Systems biology of stem cell fate and cellular reprogramming. Nat Rev Mol Cell Biol 2009 2.93
9 Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell 2013 2.71
10 Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature 2009 2.70
11 KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell 2012 2.55
12 A genomewide functional network for the laboratory mouse. PLoS Comput Biol 2008 2.25
13 Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat Biotechnol 2011 2.22
14 Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood 2011 1.86
15 Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells. Blood 2011 1.76
16 Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells 2009 1.72
17 Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity. Nat Cell Biol 2012 1.56
18 Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell 2012 1.54
19 A molecular profile of a hematopoietic stem cell niche. Proc Natl Acad Sci U S A 2002 1.53
20 Stem cells: interactive niches. Nature 2003 1.42
21 Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 2009 1.39
22 Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell 2009 1.36
23 Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proc Natl Acad Sci U S A 2006 1.35
24 Diversification of stem cell molecular repertoire by alternative splicing. Proc Natl Acad Sci U S A 2005 1.27
25 Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming. Proc Natl Acad Sci U S A 2012 1.26
26 Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells 2011 1.22
27 Epigenetic roles of MLL oncoproteins are dependent on NF-κB. Cancer Cell 2013 1.20
28 Statistical mechanics of pluripotency. Cell 2013 1.16
29 A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood 2002 1.13
30 Stem cells and reprogramming: breaking the epigenetic barrier? Trends Pharmacol Sci 2011 1.12
31 ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells. Database (Oxford) 2013 1.10
32 Toward a complete in silico, multi-layered embryonic stem cell regulatory network. Wiley Interdiscip Rev Syst Biol Med 2010 1.06
33 GATE: software for the analysis and visualization of high-dimensional time series expression data. Bioinformatics 2009 1.05
34 Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells. Nat Methods 2006 1.05
35 "Tie-ing" down the hematopoietic niche. Cell 2004 0.95
36 Reprogramming cell fates: insights from combinatorial approaches. Ann N Y Acad Sci 2012 0.93
37 Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders. Curr Opin Cardiol 2011 0.92
38 Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Nat Protoc 2012 0.91
39 SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells. BMC Syst Biol 2010 0.90
40 Genomic editing tools to model human diseases with isogenic pluripotent stem cells. Stem Cells Dev 2014 0.89
41 Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proc Natl Acad Sci U S A 2011 0.86
42 Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2. Mech Dev 2009 0.86
43 Patterning pluripotency in embryonic stem cells. Stem Cells 2013 0.86
44 Exploration of self-renewal and pluripotency in ES cells using RNAi. Methods Enzymol 2010 0.85
45 SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics 2013 0.85
46 Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells 2014 0.83
47 Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells. PLoS Comput Biol 2010 0.82
48 Cells for repair: breakout session summary. Ann N Y Acad Sci 2002 0.75