Published in Trends Pharmacol Sci on May 27, 2011
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell (2012) 1.54
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol Cell (2012) 1.52
Hematopoietic Stem Cells Count and Remember Self-Renewal Divisions. Cell (2016) 1.50
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nat Commun (2013) 1.39
A stochastic model of epigenetic dynamics in somatic cell reprogramming. Front Physiol (2012) 0.97
Stem cells and the developing mammary gland. J Mammary Gland Biol Neoplasia (2013) 0.87
Mathematical approaches to modeling development and reprogramming. Proc Natl Acad Sci U S A (2014) 0.87
Transient JMJD2B-mediated reduction of H3K9me3 levels improves reprogramming of embryonic stem cells into cloned embryos. Mol Cell Biol (2012) 0.84
Genes and Conditions Controlling Mammalian Pre- and Post-implantation Embryo Development. Curr Genomics (2015) 0.83
A role for polyamine regulators in ESC self-renewal. Cell Cycle (2012) 0.78
Letters to the editor. Ochsner J (2013) 0.75
Retroviral infection of hES cells produces random-like integration patterns. Mol Cells (2012) 0.75
DNA Methylation Dynamics Regulate the Formation of a Regenerative Wound Epithelium during Axolotl Limb Regeneration. PLoS One (2015) 0.75
Cellular reprogramming for clinical cartilage repair. Cell Biol Toxicol (2017) 0.75
Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells. PLoS One (2017) 0.75
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell (2006) 48.80
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1981) 18.96
Dissecting direct reprogramming through integrative genomic analysis. Nature (2008) 16.47
An extended transcriptional network for pluripotency of embryonic stem cells. Cell (2008) 14.64
Epigenetic memory in induced pluripotent stem cells. Nature (2010) 14.31
c-Myc regulates transcriptional pause release. Cell (2010) 11.64
Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds. Nat Biotechnol (2008) 10.97
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev (2002) 10.54
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell (2008) 10.34
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nat Biotechnol (2010) 9.24
Direct reprogramming of genetically unmodified fibroblasts into pluripotent stem cells. Nat Biotechnol (2007) 9.04
Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell (2010) 8.79
Direct cell reprogramming is a stochastic process amenable to acceleration. Nature (2009) 8.71
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. Dev Cell (2006) 8.53
Role of the murine reprogramming factors in the induction of pluripotency. Cell (2009) 7.46
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells. Cell Stem Cell (2007) 7.05
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature (2010) 7.05
How is pluripotency determined and maintained? Development (2007) 6.92
Oct4-induced pluripotency in adult neural stem cells. Cell (2009) 6.50
A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell (2008) 5.90
Chromatin remodelling during development. Nature (2010) 5.86
Global transcription in pluripotent embryonic stem cells. Cell Stem Cell (2008) 5.81
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells. Genes Dev (2007) 5.79
A fresh look at iPS cells. Cell (2009) 5.73
Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells. Nat Genet (2009) 5.52
X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet (2008) 5.18
An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell (2010) 5.00
Polycomb/Trithorax response elements and epigenetic memory of cell identity. Development (2007) 4.80
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A (2010) 4.73
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell (2010) 4.32
Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol (2008) 4.30
An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell (2008) 4.27
Chd1 regulates open chromatin and pluripotency of embryonic stem cells. Nature (2009) 4.13
SetDB1 contributes to repression of genes encoding developmental regulators and maintenance of ES cell state. Genes Dev (2009) 4.09
H2AZ is enriched at polycomb complex target genes in ES cells and is necessary for lineage commitment. Cell (2008) 3.90
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature (2010) 3.84
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proc Natl Acad Sci U S A (2009) 3.82
Epigenetic memory of an active gene state depends on histone H3.3 incorporation into chromatin in the absence of transcription. Nat Cell Biol (2007) 3.71
Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature (2009) 3.70
An expanded Oct4 interaction network: implications for stem cell biology, development, and disease. Cell Stem Cell (2010) 3.60
Transcriptional signature and memory retention of human-induced pluripotent stem cells. PLoS One (2009) 3.07
Nuclear reprogramming in cells. Science (2008) 3.04
Systems biology of stem cell fate and cellular reprogramming. Nat Rev Mol Cell Biol (2009) 2.93
CHD7 cooperates with PBAF to control multipotent neural crest formation. Nature (2010) 2.88
Polycomb group proteins set the stage for early lineage commitment. Cell Stem Cell (2010) 2.83
Stem cells and early lineage development. Cell (2008) 2.77
Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration. Nat Rev Mol Cell Biol (2011) 2.52
Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells. Genes Dev (2009) 2.18
Why myc? An unexpected ingredient in the stem cell cocktail. Cell Stem Cell (2008) 1.86
Open conformation chromatin and pluripotency. Genes Dev (2007) 1.83
Molecular analyses of human induced pluripotent stem cells and embryonic stem cells. Cell Stem Cell (2010) 1.81
Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation. Cell Stem Cell (2010) 1.74
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (2009) 1.72
Oct4 dependence of chromatin structure within the extended Nanog locus in ES cells. Genes Dev (2008) 1.68
Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo. PLoS One (2010) 1.60
Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming. Trends Pharmacol Sci (2009) 1.59
Oct4 and klf4 reprogram dermal papilla cells into induced pluripotent stem cells. Stem Cells (2010) 1.44
Inactive yet indispensable: the tale of Jarid2. Trends Cell Biol (2010) 1.24
A phosphorylated subpopulation of the histone variant macroH2A1 is excluded from the inactive X chromosome and enriched during mitosis. Proc Natl Acad Sci U S A (2008) 1.07
A stem cell molecular signature. Science (2002) 14.47
Dissecting self-renewal in stem cells with RNA interference. Nature (2006) 11.66
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature (2007) 11.14
Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev (2002) 10.71
Epigenetics: a landscape takes shape. Cell (2007) 8.29
Stem cells and their niches. Science (2006) 7.86
The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells. Nat Neurosci (2006) 4.49
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature (2010) 4.38
Wdr5 mediates self-renewal and reprogramming via the embryonic stem cell core transcriptional network. Cell (2011) 4.04
shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. Cell Stem Cell (2007) 3.40
Systems biology of stem cell fate and cellular reprogramming. Nat Rev Mol Cell Biol (2009) 2.93
RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos. Dev Biol (2004) 2.82
Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell (2013) 2.71
Systems-level dynamic analyses of fate change in murine embryonic stem cells. Nature (2009) 2.70
KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma. Cancer Cell (2012) 2.55
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8. Nature (2010) 2.49
A genomewide functional network for the laboratory mouse. PLoS Comput Biol (2008) 2.25
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells. Nat Biotechnol (2011) 2.22
Prdm16 is a physiologic regulator of hematopoietic stem cells. Blood (2011) 1.86
Polycomb Group proteins: an evolutionary perspective. Trends Genet (2007) 1.79
Systematic identification of cis-regulatory sequences active in mouse and human embryonic stem cells. PLoS Genet (2007) 1.77
Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic stem cells. Blood (2011) 1.76
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (2009) 1.72
MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation. Cell Stem Cell (2012) 1.72
Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity. Nat Cell Biol (2012) 1.56
Regulation of embryonic and induced pluripotency by aurora kinase-p53 signaling. Cell Stem Cell (2012) 1.54
A molecular profile of a hematopoietic stem cell niche. Proc Natl Acad Sci U S A (2002) 1.53
Stem cells: interactive niches. Nature (2003) 1.42
MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency. Nat Commun (2013) 1.39
Bmi-1 cooperates with Foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev (2009) 1.39
Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell (2009) 1.36
Genomewide gain-of-function genetic screen identifies functionally active genes in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2006) 1.35
H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proc Natl Acad Sci U S A (2012) 1.28
Diversification of stem cell molecular repertoire by alternative splicing. Proc Natl Acad Sci U S A (2005) 1.27
High-efficiency stem cell fusion-mediated assay reveals Sall4 as an enhancer of reprogramming. PLoS One (2008) 1.26
Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming. Proc Natl Acad Sci U S A (2012) 1.26
Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells (2011) 1.22
Epigenetic roles of MLL oncoproteins are dependent on NF-κB. Cancer Cell (2013) 1.20
Histone variants: emerging players in cancer biology. Cell Mol Life Sci (2013) 1.17
Statistical mechanics of pluripotency. Cell (2013) 1.16
A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood (2002) 1.13
ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells. Database (Oxford) (2013) 1.10
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression. Genes Dev (2012) 1.10
Toward a complete in silico, multi-layered embryonic stem cell regulatory network. Wiley Interdiscip Rev Syst Biol Med (2010) 1.06
Delivery of short hairpin RNAs--triggers of gene silencing--into mouse embryonic stem cells. Nat Methods (2006) 1.05
GATE: software for the analysis and visualization of high-dimensional time series expression data. Bioinformatics (2009) 1.05
ATRX: the case of a peculiar chromatin remodeler. Epigenetics (2012) 1.03
Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor. Nat Struct Mol Biol (2010) 1.00
"Tie-ing" down the hematopoietic niche. Cell (2004) 0.95
Reprogramming cell fates: insights from combinatorial approaches. Ann N Y Acad Sci (2012) 0.93
Induced pluripotent stem cell-derived cardiomyocytes as models for genetic cardiovascular disorders. Curr Opin Cardiol (2011) 0.92
Combining competition assays with genetic complementation strategies to dissect mouse embryonic stem cell self-renewal and pluripotency. Nat Protoc (2012) 0.91
Analysis of marker-defined HNSCC subpopulations reveals a dynamic regulation of tumor initiating properties. PLoS One (2012) 0.91
SVM classifier to predict genes important for self-renewal and pluripotency of mouse embryonic stem cells. BMC Syst Biol (2010) 0.90
Genomic editing tools to model human diseases with isogenic pluripotent stem cells. Stem Cells Dev (2014) 0.89
Partners in imprinting: noncoding RNA and polycomb group proteins. Dev Cell (2008) 0.88
Delayed differentiation in embryonic stem cells and mesodermal progenitors in the absence of CtBP2. Mech Dev (2009) 0.86
Patterning pluripotency in embryonic stem cells. Stem Cells (2013) 0.86
Hemp, an mbt domain-containing protein, plays essential roles in hematopoietic stem cell function and skeletal formation. Proc Natl Acad Sci U S A (2011) 0.86
Exploration of self-renewal and pluripotency in ES cells using RNAi. Methods Enzymol (2010) 0.85
Chromatin modifications sequentially enhance ErbB2 expression in ErbB2-positive breast cancers. Cell Rep (2013) 0.85
SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal. Epigenetics (2013) 0.85
Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells (2014) 0.83
Mapping dynamic histone acetylation patterns to gene expression in nanog-depleted murine embryonic stem cells. PLoS Comput Biol (2010) 0.82
Mitogen-activated protein kinase signaling mediates phosphorylation of polycomb ortholog Cbx7. J Biol Chem (2013) 0.77
Molecular karyotype analysis of Perkinsus atlanticus (Phylum Perkinsozoa) by pulsed field gel electrophoresis. Eur J Protistol (2007) 0.76
Cells for repair: breakout session summary. Ann N Y Acad Sci (2002) 0.75
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation. JCI Insight (2017) 0.75