Published in Exp Hematol on October 07, 2010
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Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome. Cancer Cell (2013) 2.22
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood (2011) 1.83
The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer. J Hematol Oncol (2012) 1.56
MicroRNAs in platelet production and activation. Blood (2011) 1.17
MicroRNAs are shaping the hematopoietic landscape. Haematologica (2011) 1.17
Shielding the messenger (RNA): microRNA-based anticancer therapies. Pharmacol Ther (2011) 1.12
Impacts of microRNA gene polymorphisms on the susceptibility of environmental factors leading to carcinogenesis in oral cancer. PLoS One (2012) 1.09
Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signaling. J Exp Med (2015) 0.99
The Yin and Yang of microRNAs: leukemia and immunity. Immunol Rev (2013) 0.98
MicroRNA 146 (Mir146) modulates spermatogonial differentiation by retinoic acid in mice. Biol Reprod (2013) 0.96
A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia. Leukemia (2013) 0.95
Role of heme oxygenase-1 in postnatal differentiation of stem cells: a possible cross-talk with microRNAs. Antioxid Redox Signal (2014) 0.94
MicroRNA profiling of a CD133(+) spheroid-forming subpopulation of the OVCAR3 human ovarian cancer cell line. BMC Med Genomics (2012) 0.92
MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways. PLoS One (2013) 0.90
Role of microRNA-146a in normal and malignant hematopoietic stem cell function. Front Genet (2014) 0.89
Involvement of MicroRNA in T-Cell Differentiation and Malignancy. Int J Hematol Oncol Stem Cell Res (2015) 0.88
MicroRNA control of myelopoiesis and the differentiation block in acute myeloid leukaemia. J Cell Mol Med (2012) 0.86
MicroRNA as Type I Interferon-Regulated Transcripts and Modulators of the Innate Immune Response. Front Immunol (2015) 0.86
MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1. Oncotarget (2015) 0.84
GATA2 deficiency. Curr Opin Allergy Clin Immunol (2015) 0.82
Identification of nuclear-enriched miRNAs during mouse granulopoiesis. J Hematol Oncol (2014) 0.81
MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies. ISRN Hematol (2013) 0.80
miR-146a expression level as a novel putative prognostic marker for acute promyelocytic leukemia. Dis Markers (2014) 0.80
Pathogenic microRNA's in myeloid malignancies. Front Genet (2014) 0.80
Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway. Leuk Res Treatment (2012) 0.79
MicroRNAs in Control of Stem Cells in Normal and Malignant Hematopoiesis. Curr Stem Cell Rep (2016) 0.79
MIR146A inhibits JMJD3 expression and osteogenic differentiation in human mesenchymal stem cells. FEBS Lett (2014) 0.78
Positive correlation of STAT1 and miR-146a with anemia in patients with systemic lupus erythematosus. J Clin Immunol (2013) 0.78
Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34(+) cells from patients with del(5q) myelodysplastic syndrome. Haematologica (2012) 0.78
MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia. Exp Hematol (2015) 0.77
Implication of microRNAs in the pathogenesis of MDS. Curr Pharm Des (2012) 0.77
miR-99 regulates normal and malignant hematopoietic stem cell self-renewal. J Exp Med (2017) 0.75
Specific Depletion of Leukemic Stem Cells: Can MicroRNAs Make the Difference? Cancers (Basel) (2017) 0.75
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med (2013) 19.87
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet (2010) 10.97
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res (2008) 10.18
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med (2009) 4.03
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood (2010) 4.02
Mitochondrial STAT3 supports Ras-dependent oncogenic transformation. Science (2009) 3.89
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell (2002) 3.70
In-depth characterization of the microRNA transcriptome in a leukemia progression model. Genome Res (2008) 3.55
Long-term monitoring of bacteria undergoing programmed population control in a microchemostat. Science (2005) 3.54
Recent insights into the role of Notch signaling in tumorigenesis. Blood (2005) 3.37
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med (2007) 3.05
Lipopolysaccharide signaling in endothelial cells. Lab Invest (2006) 2.58
High-throughput microfluidic single-cell RT-qPCR. Proc Natl Acad Sci U S A (2011) 2.57
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol (2002) 2.53
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med (2003) 2.42
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol (2011) 2.27
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood (2005) 2.06
Megapixel digital PCR. Nat Methods (2011) 1.94
High-throughput analysis of single hematopoietic stem cell proliferation in microfluidic cell culture arrays. Nat Methods (2011) 1.93
Smooth Muscle alpha-actin is a direct target of Notch/CSL. Circ Res (2006) 1.90
Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia. Blood (2009) 1.90
Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal. Blood (2009) 1.89
Extracellular superoxide dismutase (EC-SOD) binds to type i collagen and protects against oxidative fragmentation. J Biol Chem (2004) 1.86
Hox regulation of normal and leukemic hematopoietic stem cells. Curr Opin Hematol (2005) 1.84
In vitro and in vivo expansion of hematopoietic stem cells. Oncogene (2004) 1.83
Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation. Blood (2008) 1.79
Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia. Cancer Cell (2006) 1.74
IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity. Blood (2003) 1.73
SHIP-deficient mice are severely osteoporotic due to increased numbers of hyper-resorptive osteoclasts. Nat Med (2002) 1.71
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood (2003) 1.70
Notch signaling in cardiac development. Circ Res (2008) 1.69
The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice. J Clin Invest (2005) 1.68
The Lin28b-let-7-Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells. Nat Cell Biol (2013) 1.67
Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. J Exp Med (2002) 1.62
Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells. Proc Natl Acad Sci U S A (2002) 1.61
High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector. J Clin Invest (2008) 1.61
Notch activation induces endothelial cell cycle arrest and participates in contact inhibition: role of p21Cip1 repression. Mol Cell Biol (2004) 1.61
Canadian anaplastic lymphoma kinase study: a model for multicenter standardization and optimization of ALK testing in lung cancer. J Thorac Oncol (2014) 1.55
Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. Stem Cells (2005) 1.52
Activated Notch4 inhibits angiogenesis: role of beta 1-integrin activation. Mol Cell Biol (2002) 1.52
Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol Cell Biol (2003) 1.50
Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells. Blood (2011) 1.44
Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol (2004) 1.43
Serum microRNAs as a novel class of biomarkers: a comprehensive review of the literature. Exp Hematol (2010) 1.43
TRAF6 is an amplified oncogene bridging the RAS and NF-κB pathways in human lung cancer. J Clin Invest (2011) 1.42
The Opitz syndrome gene Mid1 is transcribed from a human endogenous retroviral promoter. Mol Biol Evol (2002) 1.42
Identification of sokotrasterol sulfate as a novel proangiogenic steroid. Circ Res (2006) 1.41
A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities. Proc Natl Acad Sci U S A (2012) 1.41
Unraveling the crucial roles of Meis1 in leukemogenesis and normal hematopoiesis. Genes Dev (2007) 1.41
Microfluidic single cell analysis: from promise to practice. Curr Opin Chem Biol (2012) 1.41
MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML. Blood (2007) 1.37
Hox genes: from leukemia to hematopoietic stem cell expansion. Ann N Y Acad Sci (2005) 1.37
Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. Blood (2010) 1.36
High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells. J Clin Invest (2004) 1.35
Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells. PLoS Med (2006) 1.35
A complete microfluidic screening platform for rational protein crystallization. J Am Chem Soc (2007) 1.33
Minimal contribution of marrow-derived endothelial precursors to tumor vasculature. J Immunol (2005) 1.31
Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood (2002) 1.30
Notch4 inhibits endothelial apoptosis via RBP-Jkappa-dependent and -independent pathways. J Biol Chem (2003) 1.29
Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia. Proc Natl Acad Sci U S A (2004) 1.27
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex. Cancer Cell (2011) 1.25
Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. J Biol Chem (2006) 1.23
The methyltransferase G9a regulates HoxA9-dependent transcription in AML. Genes Dev (2014) 1.23
Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase. Dev Cell (2011) 1.22
Roles of reactive oxygen species in angiopoietin-1/tie-2 receptor signaling. FASEB J (2005) 1.21
Circulating microRNAs in hematological diseases: principles, challenges, and perspectives. Blood (2013) 1.19
Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family. Gene (2006) 1.16
Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA. Mol Ther Nucleic Acids (2012) 1.16
The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia. Blood (2006) 1.14
The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity (2003) 1.14
Near-maximal expansions of hematopoietic stem cells in culture using NUP98-HOX fusions. Exp Hematol (2007) 1.13
Phase knowledge enables rational screens for protein crystallization. Proc Natl Acad Sci U S A (2006) 1.13
Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases. FASEB J (2003) 1.12
A microfluidic device for multiplexed protein detection in nano-liter volumes. Anal Biochem (2008) 1.12
The inositol 5'-phosphatase SHIP-1 and the Src kinase Lyn negatively regulate macrophage colony-stimulating factor-induced Akt activity. J Biol Chem (2003) 1.12
Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes. PLoS One (2007) 1.10
HIF-1 induction attenuates Nrf2-dependent IL-8 expression in human endothelial cells. Antioxid Redox Signal (2009) 1.09
Homeostasis and regeneration of the hematopoietic stem cell pool are altered in SHIP-deficient mice. Blood (2003) 1.09
Differential regulation of transforming growth factor beta signaling pathways by Notch in human endothelial cells. J Biol Chem (2009) 1.07
Involvement of endothelial progenitor cells in tumor vascularization. Microvasc Res (2010) 1.06
Linkage of Meis1 leukemogenic activity to multiple downstream effectors including Trib2 and Ccl3. Exp Hematol (2008) 1.05