Published in Blood on October 20, 2010
Targeting IRAK1 as a therapeutic approach for myelodysplastic syndrome. Cancer Cell (2013) 2.22
NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood (2011) 1.91
miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood (2015) 1.56
The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer. J Hematol Oncol (2012) 1.56
MiR-124 suppresses growth of human colorectal cancer by inhibiting STAT3. PLoS One (2013) 1.28
CopraRNA and IntaRNA: predicting small RNA targets, networks and interaction domains. Nucleic Acids Res (2014) 1.23
The tumor suppressive role of miRNA-370 by targeting FoxM1 in acute myeloid leukemia. Mol Cancer (2012) 1.14
FOXP3 Controls an miR-146/NF-κB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells. Cancer Res (2015) 1.08
A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL. Hum Mol Genet (2011) 1.07
MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias. Blood Cancer J (2011) 1.00
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network. Cell Rep (2014) 0.99
DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma. World J Gastroenterol (2014) 0.99
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs. PLoS Genet (2014) 0.96
MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells. Blood (2013) 0.96
Integration of SNP and mRNA arrays with microRNA profiling reveals that MiR-370 is upregulated and targets NF1 in acute myeloid leukemia. PLoS One (2012) 0.92
MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways. PLoS One (2013) 0.90
Circulating microRNAs as biomarkers - True Blood? Genome Med (2011) 0.82
MicroRNA gene dosage alterations and drug response in lung cancer. J Biomed Biotechnol (2011) 0.81
miR-146a expression level as a novel putative prognostic marker for acute promyelocytic leukemia. Dis Markers (2014) 0.80
The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes. Blood Cancer J (2015) 0.80
Characterization of miRNomes in acute and chronic myeloid leukemia cell lines. Genomics Proteomics Bioinformatics (2014) 0.79
Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway. Leuk Res Treatment (2012) 0.79
Genomic tools in acute myeloid leukemia: From the bench to the bedside. Cancer (2014) 0.79
Premalignant PTEN-deficient thymocytes activate microRNAs miR-146a and miR-146b as a cellular defense against malignant transformation. Blood (2014) 0.78
miRNA-mediated deregulation in leukemia. Front Genet (2012) 0.78
The Role of MicroRNAs in Hematopoietic Stem Cell and Leukemic Stem Cell Function. Ther Adv Hematol (2011) 0.77
Implication of microRNAs in the pathogenesis of MDS. Curr Pharm Des (2012) 0.77
Clonal evolution in myelodysplastic syndromes with isolated del(5q): the importance of genetic monitoring. Haematologica (2011) 0.76
Understanding the role of miRNA in regulating NF-κB in blood cancer. Am J Cancer Res (2011) 0.76
Stem and progenitor cell alterations in myelodysplastic syndromes. Blood (2017) 0.75
MicroRNA-mRNA Pairs Associated with Outcome in AML: From In Vitro Cell-Based Studies to AML Patients. Front Pharmacol (2016) 0.75
MicroRNAs in the pathogenesis of myelodysplastic syndromes and myeloid leukaemia. Curr Opin Hematol (2014) 0.75
MicroRNAs and acute myeloid leukemia: therapeutic implications and emerging concepts. Blood (2017) 0.75
Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing. Nat Methods (2007) 45.04
Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature (2004) 24.40
International network of cancer genome projects. Nature (2010) 20.35
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med (2013) 19.87
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature (2009) 18.08
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet (2005) 15.37
The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol (2010) 13.99
ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med (2010) 13.07
The clonal and mutational evolution spectrum of primary triple-negative breast cancers. Nature (2012) 11.91
The somatic genomic landscape of glioblastoma. Cell (2013) 11.73
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin. Nat Genet (2010) 10.97
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res (2008) 10.18
Profiling the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. Biotechniques (2008) 10.02
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma. Nature (2011) 9.71
De novo assembly and analysis of RNA-seq data. Nat Methods (2010) 9.69
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res (2004) 9.18
The genome of the kinetoplastid parasite, Leishmania major. Science (2005) 8.64
A comprehensive analysis of common copy-number variations in the human genome. Am J Hum Genet (2006) 8.61
De novo transcriptome assembly with ABySS. Bioinformatics (2009) 8.38
A tiling resolution DNA microarray with complete coverage of the human genome. Nat Genet (2004) 7.68
Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol (2010) 7.00
Next-generation tag sequencing for cancer gene expression profiling. Genome Res (2009) 6.50
The functional role of long non-coding RNA in human carcinomas. Mol Cancer (2011) 6.37
Dynamic remodeling of individual nucleosomes across a eukaryotic genome in response to transcriptional perturbation. PLoS Biol (2008) 5.88
Mutation of FOXL2 in granulosa-cell tumors of the ovary. N Engl J Med (2009) 5.63
Alternative expression analysis by RNA sequencing. Nat Methods (2010) 5.02
A physical map of the mouse genome. Nature (2002) 4.97
The genetic landscape of high-risk neuroblastoma. Nat Genet (2013) 4.71
deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data. PLoS Comput Biol (2011) 4.66
Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell (2012) 4.41
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell (2010) 4.34
Human illness from avian influenza H7N3, British Columbia. Emerg Infect Dis (2004) 4.29
Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding. Genome Res (2008) 4.11
Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing. Nucleic Acids Res (2008) 4.08
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype. Nat Med (2009) 4.03
SNVMix: predicting single nucleotide variants from next-generation sequencing of tumors. Bioinformatics (2010) 4.02
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation. Blood (2010) 4.02
Mitochondrial STAT3 supports Ras-dependent oncogenic transformation. Science (2009) 3.89
Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell (2008) 3.87
Massively parallel sequencing of the polyadenylated transcriptome of C. elegans. Genome Res (2009) 3.83
HOXB4-induced expansion of adult hematopoietic stem cells ex vivo. Cell (2002) 3.70
Resolving the resolution of array CGH. Genomics (2007) 3.66
Applications of new sequencing technologies for transcriptome analysis. Annu Rev Genomics Hum Genet (2009) 3.59
In-depth characterization of the microRNA transcriptome in a leukemia progression model. Genome Res (2008) 3.55
PIK3CA mutations and copy number gains in human lung cancers. Cancer Res (2008) 3.42
Recent insights into the role of Notch signaling in tumorigenesis. Blood (2005) 3.37
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers. Nature (2011) 3.22
JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data. Bioinformatics (2012) 3.21
SKPs derive from hair follicle precursors and exhibit properties of adult dermal stem cells. Cell Stem Cell (2009) 3.20
DNA methylation and SETDB1/H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs. Cell Stem Cell (2011) 3.10
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin. J Exp Med (2007) 3.05
Massively parallel sequencing: the next big thing in genetic medicine. Am J Hum Genet (2009) 3.01
De novo genome sequence assembly of a filamentous fungus using Sanger, 454 and Illumina sequence data. Genome Biol (2009) 2.99
Analysis of the prostate cancer cell line LNCaP transcriptome using a sequencing-by-synthesis approach. BMC Genomics (2006) 2.98
Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines. PLoS One (2009) 2.79
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature (2013) 2.76
The Human Epigenome Browser at Washington University. Nat Methods (2011) 2.62
Evolution of an adenocarcinoma in response to selection by targeted kinase inhibitors. Genome Biol (2010) 2.60
Lipopolysaccharide signaling in endothelial cells. Lab Invest (2006) 2.58
Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathol (2011) 2.53
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol (2002) 2.53
Integrating copy number polymorphisms into array CGH analysis using a robust HMM. Bioinformatics (2006) 2.50
Multiple microalterations detected at high frequency in oral cancer. Cancer Res (2005) 2.47
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med (2003) 2.42
Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential. Blood (2009) 2.41
Human cancer long non-coding RNA transcriptomes. PLoS One (2011) 2.38
A mouse atlas of gene expression: large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells. Proc Natl Acad Sci U S A (2005) 2.35
Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies. Lancet Oncol (2013) 2.32
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers. J Pathol (2011) 2.27
Feature-based classifiers for somatic mutation detection in tumour-normal paired sequencing data. Bioinformatics (2011) 2.26
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. N Engl J Med (2011) 2.25
The shaping and functional consequences of the microRNA landscape in breast cancer. Nature (2013) 2.22
The completion of the Mammalian Gene Collection (MGC). Genome Res (2009) 2.21
Slug is a direct Notch target required for initiation of cardiac cushion cellularization. J Cell Biol (2008) 2.21
High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH. Int J Cancer (2006) 2.16
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression. Genome Res (2012) 2.10
Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation. Circ Res (2004) 2.10
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Res (2012) 2.09
A stepwise framework for the normalization of array CGH data. BMC Bioinformatics (2005) 2.08
Loss of expression of the Hoxa-9 homeobox gene impairs the proliferation and repopulating ability of hematopoietic stem cells. Blood (2005) 2.06