Published in Cell Signal on October 16, 2010
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J Mol Med (Berl) (2011) 2.26
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Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
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Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev (2007) 1.96
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Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal (2013) 1.65
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Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors. Prog Neurobiol (2009) 1.57
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev (2011) 1.53
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation (2009) 1.46
Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). Immunol Lett (2012) 1.46
Celastrol: Molecular targets of Thunder God Vine. Biochem Biophys Res Commun (2010) 1.45
Maturation of autophagosomes and endosomes: a key role for Rab7. Biochim Biophys Acta (2012) 1.43
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal (2011) 1.41
Pharmacokinetics, efficacy and safety profiles of preserved and preservative-free tafluprost in healthy volunteers. Acta Ophthalmol Suppl (Oxf ) (2008) 1.39
Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling. Cell Signal (2009) 1.34
Molecular mechanisms of retinal pigment epithelium damage and development of age-related macular degeneration. Acta Ophthalmol (2011) 1.31
SIRT1: regulation of longevity via autophagy. Cell Signal (2009) 1.29
Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication. Acta Ophthalmol (2010) 1.29
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype. Eur J Neurosci (2011) 1.26
Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med (2010) 1.22
Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS One (2013) 1.20
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Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases. Cell Mol Life Sci (2012) 1.19
Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. Immunol Lett (2008) 1.18
SIRT1 longevity factor suppresses NF-kappaB -driven immune responses: regulation of aging via NF-kappaB acetylation? Bioessays (2008) 1.17
AMP-activated protein kinase: a potential player in Alzheimer's disease. J Neurochem (2011) 1.16
Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. J Cell Mol Med (2008) 1.16
Regulatory role of HIF-1alpha in the pathogenesis of age-related macular degeneration (AMD). Ageing Res Rev (2009) 1.16
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med (2008) 1.14
Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration. Int J Mol Sci (2013) 1.13
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome. Prog Neurobiol (2013) 1.12
NF-kappaB signaling in the aging process. J Clin Immunol (2009) 1.10
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cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure. Biochim Biophys Acta (2002) 1.06
ER stress and hormetic regulation of the aging process. Ageing Res Rev (2010) 1.04
Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process. Ageing Res Rev (2012) 1.03
Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration. PLoS One (2008) 1.03
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease. Prog Neurobiol (2011) 1.02
Comparison of three intraocular pressure measurement methods including biomechanical properties of the cornea. Invest Ophthalmol Vis Sci (2014) 1.01
Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol Life Sci (2010) 1.01
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. Prog Neurobiol (2010) 0.99
Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res (2009) 0.97
Symptom score questionnaire for nasolacrimal duct obstruction in adults--a novel tool to assess the outcome after endoscopic dacryocystorhinostomy. Rhinology (2010) 0.97
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells. Mol Vis (2010) 0.95
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Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology (2013) 0.92
A prospective study on postoperative pain after cataract surgery. Clin Ophthalmol (2013) 0.90
Siglec receptors and hiding plaques in Alzheimer's disease. J Mol Med (Berl) (2009) 0.90
Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process. J Cell Physiol (2010) 0.90
Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. Tissue Eng Part A (2014) 0.90
The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells. Immunol Lett (2007) 0.89
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The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells. Mol Vis (2012) 0.88
Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells. Eur J Pharmacol (2008) 0.88
Regression of necrotizing scleritis in Wegener's granulomatosis after infliximab treatment. Acta Ophthalmol (2009) 0.88
Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney. Antioxid Redox Signal (2007) 0.87
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Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis (2007) 0.86
ROCK, PAK, and Toll of synapses in Alzheimer's disease. Biochem Biophys Res Commun (2008) 0.85
Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study. Acta Ophthalmol (2011) 0.85
Postoperative pain after cataract surgery. J Cataract Refract Surg (2013) 0.85
Imiquimod in the treatment of eyelid basal cell carcinoma. Acta Ophthalmol Scand (2007) 0.85
Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells. Pharmacol Res (2011) 0.85
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process. J Mol Med (Berl) (2014) 0.84
Autophagy--hot topic in AMD. Acta Ophthalmol (2010) 0.84
Protein-oxidized phospholipid interactions in cellular signaling for cell death: from biophysics to clinical correlations. Biochim Biophys Acta (2012) 0.84
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Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process. Curr Opin Clin Nutr Metab Care (2012) 0.83
Filter-cultured ARPE-19 cells as outer blood-retinal barrier model. Eur J Pharm Sci (2010) 0.83
Genetics vs. entropy: longevity factors suppress the NF-kappaB-driven entropic aging process. Ageing Res Rev (2009) 0.83
Genetic variability in DNA repair proteins in age-related macular degeneration. Int J Mol Sci (2012) 0.83
NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes? Biochem Biophys Res Commun (2008) 0.82
Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro. Mol Vis (2011) 0.82
SIRT1 regulates the ribosomal DNA locus: epigenetic candles twinkle longevity in the Christmas tree. Biochem Biophys Res Commun (2008) 0.82
ADAMTS9 locus associates with increased risk of wet AMD. Acta Ophthalmol (2014) 0.81
5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration. Rejuvenation Res (2011) 0.81
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Altered calcium signaling in an experimental model of glaucoma. Invest Ophthalmol Vis Sci (2010) 0.80
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Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function. Cell Mol Life Sci (2013) 0.79
Potential of epigenetic mechanisms in AMD pathology. Front Biosci (Schol Ed) (2013) 0.79
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Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice. Mol Vis (2012) 0.78
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Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies. Mol Vis (2012) 0.77
High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis. Biorheology (2002) 0.77
Hypoxic conditions stimulate the release of B-type natriuretic peptide from human retinal pigment epithelium cell culture. Acta Ophthalmol (2014) 0.77
Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration. Mol Vis (2009) 0.76
Recovery and patient satisfaction after cataract surgery. A one-year prospective follow-up study. Acta Ophthalmol (2014) 0.76
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Specific induction of heat shock protein 90beta by high hydrostatic pressure. Biorheology (2003) 0.76