Published in Acta Ophthalmol on November 23, 2011
NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration. Invest Ophthalmol Vis Sci (2013) 1.58
DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE). PLoS One (2013) 1.49
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy (2013) 1.34
Aging is not a disease: distinguishing age-related macular degeneration from aging. Prog Retin Eye Res (2013) 1.29
Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis. PLoS One (2013) 1.16
Mechanisms for countering oxidative stress and damage in retinal pigment epithelium. Int Rev Cell Mol Biol (2012) 1.05
Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis in mice. PLoS One (2013) 1.04
Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia/reperfusion injury in mice. Mol Neurodegener (2013) 0.95
Phagocyte dysfunction, tissue aging and degeneration. Ageing Res Rev (2013) 0.91
Potential Sources and Roles of Adaptive Immunity in Age-Related Macular Degeneration: Shall We Rename AMD into Autoimmune Macular Disease? Autoimmune Dis (2014) 0.91
[Clinical, morphological and molecular biological characteristics of the aging eye]. Ophthalmologe (2016) 0.90
CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Sci Rep (2013) 0.88
Translational attenuation differentially alters the fate of disease-associated fibulin proteins. FASEB J (2012) 0.88
Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration. PLoS One (2015) 0.87
Toll-like receptor 3 (TLR3) protects retinal pigmented epithelium (RPE) cells from oxidative stress through a STAT3-dependent mechanism. Mol Immunol (2012) 0.86
Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death. PLoS One (2013) 0.86
Zeaxanthin induces Nrf2-mediated phase II enzymes in protection of cell death. Cell Death Dis (2014) 0.86
A novel protective role for the innate immunity Toll-Like Receptor 3 (TLR3) in the retina via Stat3. Mol Cell Neurosci (2014) 0.85
Risk factors and biomarkers of age-related macular degeneration. Prog Retin Eye Res (2016) 0.85
Enhancing RPE Cell-Based Therapy Outcomes for AMD: The Role of Bruch's Membrane. Transl Vis Sci Technol (2014) 0.83
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells. Autophagy (2015) 0.81
Dysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration. Cell Death Dis (2017) 0.80
Dementia of the eye: the role of amyloid beta in retinal degeneration. Eye (Lond) (2015) 0.79
Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes. Invest Ophthalmol Vis Sci (2015) 0.79
Regulatory regions of the paraoxonase 1 (PON1) gene are associated with neovascular age-related macular degeneration (AMD). Age (Dordr) (2012) 0.78
Acetylcholinesterase function in apoptotic retina pigment epithelial cells induced by H2O2. Int J Ophthalmol (2013) 0.78
Photobiomodulation with 670 nm light increased phagocytosis in human retinal pigment epithelial cells. Mol Vis (2015) 0.78
Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons. BMC Neurosci (2015) 0.77
Arundic acid attenuates retinal ganglion cell death by increasing glutamate/aspartate transporter expression in a model of normal tension glaucoma. Cell Death Dis (2015) 0.77
Small molecule mediated proliferation of primary retinal pigment epithelial cells. ACS Chem Biol (2013) 0.77
Friend or Foe? Resident Microglia vs Bone Marrow-Derived Microglia and Their Roles in the Retinal Degeneration. Mol Neurobiol (2016) 0.76
Looking into the future: Using induced pluripotent stem cells to build two and three dimensional ocular tissue for cell therapy and disease modeling. Brain Res (2015) 0.76
Molecular imaging of retinal disease. J Ocul Pharmacol Ther (2013) 0.76
Contributions of age-related alterations of the retinal pigment epithelium and of glia to the AMD-like pathology in OXYS rats. Sci Rep (2017) 0.75
Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study. Clin Ophthalmol (2016) 0.75
The small tellurium-based compound SAS suppresses inflammation in human retinal pigment epithelium. Mol Vis (2016) 0.75
Exogenous NAD(+) decreases oxidative stress and protects H2O2-treated RPE cells against necrotic death through the up-regulation of autophagy. Sci Rep (2016) 0.75
Histological and Electrophysiological Changes in the Retinal Pigment Epithelium after Injection of Sodium Iodate in the Orbital Venus Plexus of Pigmented Rats. J Ophthalmic Vis Res (2016) 0.75
Monte Carlo simulation of laser beams interaction with the human eye using Geant4. Biomed Eng Online (2014) 0.75
Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation. J Cell Mol Med (2016) 0.75
Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress. Free Radic Biol Med (2017) 0.75
Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo. PLoS One (2016) 0.75
Protective Mechanisms of the Mitochondrial-Derived Peptide Humanin in Oxidative and Endoplasmic Reticulum Stress in RPE Cells. Oxid Med Cell Longev (2017) 0.75
[Atrophy of the macula in the context of its wet, age-related degeneration : An inescapable consequence of anti-VEGF therapy?] Ophthalmologe (2016) 0.75
[Morphological features of myopic choroidal neovascularization: differences to neovascular age-related macular degeneration]. Ophthalmologe (2012) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan. J Mol Med (Berl) (2011) 2.26
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging. Ageing Res Rev (2007) 1.96
Evaluation of tear osmolarity in non-Sjögren and Sjögren syndrome dry eye patients with the TearLab system. Cornea (2012) 1.74
Regulation of the aging process by autophagy. Trends Mol Med (2009) 1.69
Reliability and repeatability of swept-source Fourier-domain optical coherence tomography and Scheimpflug imaging in keratoconus. J Cataract Refract Surg (2012) 1.68
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. Cell Signal (2013) 1.65
Inflammaging: disturbed interplay between autophagy and inflammasomes. Aging (Albany NY) (2012) 1.58
Inflammation in Alzheimer's disease: amyloid-beta oligomers trigger innate immunity defence via pattern recognition receptors. Prog Neurobiol (2009) 1.57
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network. Ageing Res Rev (2011) 1.53
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology. J Neuroinflammation (2009) 1.46
Activation of neural progenitor cells in human eyes with proliferative vitreoretinopathy. Exp Eye Res (2012) 1.46
Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). Immunol Lett (2012) 1.46
Celastrol: Molecular targets of Thunder God Vine. Biochem Biophys Res Commun (2010) 1.45
Maturation of autophagosomes and endosomes: a key role for Rab7. Biochim Biophys Acta (2012) 1.43
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP). Cell Signal (2011) 1.41
Pharmacokinetics, efficacy and safety profiles of preserved and preservative-free tafluprost in healthy volunteers. Acta Ophthalmol Suppl (Oxf ) (2008) 1.39
Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling. Cell Signal (2009) 1.34
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration. Autophagy (2013) 1.34
Two-year safety and efficacy of ranibizumab 0.5 mg in diabetic macular edema: interim analysis of the RESTORE extension study. Ophthalmology (2013) 1.33
Cell death and autophagy: cytokines, drugs, and nutritional factors. Toxicology (2008) 1.31
SIRT1: regulation of longevity via autophagy. Cell Signal (2009) 1.29
Switching from a preserved to a preservative-free prostaglandin preparation in topical glaucoma medication. Acta Ophthalmol (2010) 1.29
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype. Eur J Neurosci (2011) 1.26
Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med (2010) 1.22
Autophagy activation clears ELAVL1/HuR-mediated accumulation of SQSTM1/p62 during proteasomal inhibition in human retinal pigment epithelial cells. PLoS One (2013) 1.20
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma. Graefes Arch Clin Exp Ophthalmol (2006) 1.19
Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases. Cell Mol Life Sci (2012) 1.19
Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. Immunol Lett (2008) 1.18
SIRT1 longevity factor suppresses NF-kappaB -driven immune responses: regulation of aging via NF-kappaB acetylation? Bioessays (2008) 1.17
AMP-activated protein kinase: a potential player in Alzheimer's disease. J Neurochem (2011) 1.16
Regulatory role of HIF-1alpha in the pathogenesis of age-related macular degeneration (AMD). Ageing Res Rev (2009) 1.16
Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology. J Cell Mol Med (2008) 1.16
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells. J Cell Mol Med (2008) 1.14
Mitochondrial and nuclear DNA damage and repair in age-related macular degeneration. Int J Mol Sci (2013) 1.13
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome. Prog Neurobiol (2013) 1.12
Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging. Cell Signal (2010) 1.11
Neurogenesis in the adult spinal cord in an experimental model of multiple sclerosis. Eur J Neurosci (2006) 1.11
NF-kappaB signaling in the aging process. J Clin Immunol (2009) 1.10
Stem cells from the adult human brain develop into functional neurons in culture. Exp Cell Res (2003) 1.09
Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process. Int J Mol Sci (2013) 1.07
cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure. Biochim Biophys Acta (2002) 1.06
ER stress and hormetic regulation of the aging process. Ageing Res Rev (2010) 1.04
Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: impact on the aging process. Ageing Res Rev (2012) 1.03
Multifactor effects and evidence of potential interaction between complement factor H Y402H and LOC387715 A69S in age-related macular degeneration. PLoS One (2008) 1.03
ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages. PLoS One (2012) 1.03
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease. Prog Neurobiol (2011) 1.02
Multiple sclerosis-associated uveitis. Ocul Immunol Inflamm (2004) 1.02
Apoptotic response of uveal melanoma cells upon treatment with chelidonine, sanguinarine and chelerythrine. Cancer Lett (2005) 1.02
Comparison of three intraocular pressure measurement methods including biomechanical properties of the cornea. Invest Ophthalmol Vis Sci (2014) 1.01
Apoptosis and aging: increased resistance to apoptosis enhances the aging process. Cell Mol Life Sci (2010) 1.01
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease. Prog Neurobiol (2010) 0.99
Anterior segment changes with age and during accommodation measured with partial coherence interferometry. J Cataract Refract Surg (2007) 0.98
Efflux protein expression in human retinal pigment epithelium cell lines. Pharm Res (2009) 0.97
Symptom score questionnaire for nasolacrimal duct obstruction in adults--a novel tool to assess the outcome after endoscopic dacryocystorhinostomy. Rhinology (2010) 0.97
Assessment of corneal topography indices after collagen crosslinking for keratoconus. Eur J Ophthalmol (2013) 0.96
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells. Mol Vis (2010) 0.95
Retinal arterial macroaneurysms. Acta Ophthalmol (2013) 0.95
Ex vivo expanded autologous limbal epithelial cells on amniotic membrane using a culture medium with human serum as single supplement. Exp Eye Res (2012) 0.94
Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. Biochem Biophys Res Commun (2007) 0.93
Keratometry evaluations with the Pentacam high resolution in comparison with the automated keratometry and conventional corneal topography. Cornea (2012) 0.92
Regeneration of infarcted myocardium with resveratrol-modified cardiac stem cells. J Cell Mol Med (2012) 0.92
Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology (2013) 0.92
Siglec receptors and hiding plaques in Alzheimer's disease. J Mol Med (Berl) (2009) 0.90
A prospective study on postoperative pain after cataract surgery. Clin Ophthalmol (2013) 0.90
Glycolysis links p53 function with NF-kappaB signaling: impact on cancer and aging process. J Cell Physiol (2010) 0.90
Transplantation of stem cells from the adult human brain to the adult rat brain. Neurosurgery (2007) 0.90
Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. Tissue Eng Part A (2014) 0.90
Pseudophakic accommodation and pseudoaccommodation under physiological conditions measured with partial coherence interferometry. J Cataract Refract Surg (2006) 0.89
Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis. Stem Cells (2006) 0.89
Cellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization. Int J Biochem Cell Biol (2013) 0.89
The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells. Immunol Lett (2007) 0.89
A comparison between stem cells from the adult human brain and from brain tumors. Neurosurgery (2008) 0.89
Endoscopically harvested stem cells: a putative method in future autotransplantation. Neurosurgery (2005) 0.89
The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells. Mol Vis (2012) 0.88
Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy. J Proteomics (2012) 0.88
Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells. Eur J Pharmacol (2008) 0.88
Isolation of human multipotent neural progenitors from adult filum terminale. Stem Cells Dev (2009) 0.88
Regression of necrotizing scleritis in Wegener's granulomatosis after infliximab treatment. Acta Ophthalmol (2009) 0.88
Reliability of the corneal thickness measurements with the Pentacam HR imaging system and ultrasound pachymetry. Cornea (2011) 0.87
Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney. Antioxid Redox Signal (2007) 0.87
Stem cells of the adult cornea: from cytometric markers to therapeutic applications. Cytometry A (2009) 0.87
Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process. Int J Cell Biol (2012) 0.87
Immunolocalization of EMMPRIN (CD147) in the human eye and detection of soluble form of EMMPRIN in ocular fluids. Curr Eye Res (2006) 0.87
Bilateral central retinal vein occlusion caused by malignant hypertension in a young patient. Clin Exp Hypertens (2010) 0.86
Clinical transplantation of ex vivo expanded autologous limbal epithelial cells using a culture medium with human serum as single supplement: a retrospective case series. Acta Ophthalmol (2012) 0.86
Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma. Mol Vis (2007) 0.86
Predifferentiated brain-derived adult human progenitor cells migrate toward ischemia after transplantation to the adult rat brain. Neurosurgery (2011) 0.86
[Acanthamoeba keratitis]. Orv Hetil (2008) 0.85
ROCK, PAK, and Toll of synapses in Alzheimer's disease. Biochem Biophys Res Commun (2008) 0.85
Postoperative pain after cataract surgery. J Cataract Refract Surg (2013) 0.85
Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study. Acta Ophthalmol (2011) 0.85
Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium. PLoS One (2012) 0.85