Published in N Engl J Med on October 14, 2010
Charting a course for genomic medicine from base pairs to bedside. Nature (2011) 9.39
Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations. Eur Respir J (2012) 7.18
Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. Pharmacogenomics (2012) 1.63
Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases. PLoS Genet (2012) 1.55
Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation. Curr Pharmacogenomics Person Med (2011) 1.49
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa. Genome Res (2015) 1.39
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
Mapping of disease-associated variants in admixed populations. Genome Biol (2011) 1.21
Ethical and legal implications of whole genome and whole exome sequencing in African populations. BMC Med Ethics (2013) 1.14
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Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans. PLoS One (2011) 0.99
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Genetic variants of TSLP and asthma in an admixed urban population. PLoS One (2011) 0.98
Translational Genomics in Low- and Middle-Income Countries: Opportunities and Challenges. Public Health Genomics (2015) 0.93
Disease-associated alleles in genome-wide association studies are enriched for derived low frequency alleles relative to HapMap and neutral expectations. BMC Med Genomics (2010) 0.90
Awareness of direct-to-consumer genetic tests and use of genetic tests among Puerto Rican adults, 2009. Prev Chronic Dis (2011) 0.90
Clinical and pharmacogenomic implications of genetic variation in a Southern Ethiopian population. Pharmacogenomics J (2014) 0.89
African ancestry, early life exposures, and respiratory morbidity in early childhood. Clin Exp Allergy (2011) 0.88
First genome-wide association study in an Australian aboriginal population provides insights into genetic risk factors for body mass index and type 2 diabetes. PLoS One (2015) 0.87
Why personalized medicine will fail if we stay the course. Per Med (2012) 0.86
The relationship between polymorphisms on chromosome 9p21 and age of onset of coronary heart disease in black and white women. Genet Test Mol Biomarkers (2011) 0.85
Health aspects of the pre-departure phase of migration. PLoS Med (2011) 0.84
Genome-wide association studies in Africans and African Americans: expanding the framework of the genomics of human traits and disease. Public Health Genomics (2014) 0.84
Translating biotechnology to knowledge-based innovation, peace, and development? Deploy a Science Peace Corps--an open letter to world leaders. OMICS (2014) 0.82
Stroke genomics in people of African ancestry: charting new paths. Cardiovasc J Afr (2015) 0.81
Impact of ethnicity on progress of glycaemic control in 131,935 newly diagnosed patients with type 2 diabetes: a nationwide observational study from the Swedish National Diabetes Register. BMJ Open (2015) 0.81
Genetic African Ancestry and Markers of Mineral Metabolism in CKD. Clin J Am Soc Nephrol (2016) 0.80
Diversity and inclusion in genomic research: why the uneven progress? J Community Genet (2017) 0.79
Discussing race-related limitations of genomic testing for colon cancer risk: implications for education and counseling. Soc Sci Med (2014) 0.78
Pharmacogenomic implications of the evolutionary history of infectious diseases in Africa. Pharmacogenomics J (2016) 0.78
Admixture into and within sub-Saharan Africa. Elife (2016) 0.77
Type 2 Diabetes Genetic Predisposition, Obesity, and All-Cause Mortality Risk in the U.S.: A Multiethnic Analysis. Diabetes Care (2016) 0.76
A Single Nucleotide Polymorphism in Catalase Is Strongly Associated with Ovarian Cancer Survival. PLoS One (2015) 0.76
Social Determinants of Racial Disparities in CKD. J Am Soc Nephrol (2016) 0.76
Neurobehavioral assessment in forensic practice. Int J Law Psychiatry (2012) 0.76
Nature versus Nurture: Does Genetic Ancestry Alter the Effect of Air Pollution in Children with Asthma? Am J Respir Crit Care Med (2016) 0.75
Recruitment of Yoruba families from Nigeria for genetic research: experience from a multisite keloid study. BMC Med Ethics (2014) 0.75
Pituitary tumors in patients with MEN1 syndrome. Clinics (Sao Paulo) (2012) 0.75
Medical genetics teaching in Iranian medical schools, especially Ahvaz, south of Iran. J Adv Med Educ Prof (2014) 0.75
Health regulatory communications of well-established safety-related pharmacogenomics associations in six developed countries: an evaluation of alignment. Pharmacogenomics J (2016) 0.75
BiDil in the Clinic: An Interdisciplinary Investigation of Physicians' Prescription Patterns of a Race-Based Therapy. AJOB Empir Bioeth (2014) 0.75
MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies. PLoS One (2017) 0.75
Recent Advances in the Molecular Genetics of Familial Hypertrophic Cardiomyopathy in South Asian Descendants. Front Physiol (2016) 0.75
Population effect model identifies gene expression predictors of survival outcomes in lung adenocarcinoma for both Caucasian and Asian patients. PLoS One (2017) 0.75
Genome Wide Association Studies of Chemotherapeutic Toxicities: Genomics of Inequality. Clin Cancer Res (2017) 0.75
Analysis of genetic inheritance in a family quartet by whole-genome sequencing. Science (2010) 18.45
Mobile elements create structural variation: analysis of a complete human genome. Genome Res (2009) 7.06
Genetic evidence for high-altitude adaptation in Tibet. Science (2010) 5.37
Human population genetic structure and inference of group membership. Am J Hum Genet (2003) 4.73
Mutations in embryonic myosin heavy chain (MYH3) cause Freeman-Sheldon syndrome and Sheldon-Hall syndrome. Nat Genet (2006) 3.94
Large-scale SNP analysis reveals clustered and continuous patterns of human genetic variation. Hum Genomics (2005) 3.77
Using VAAST to identify an X-linked disorder resulting in lethality in male infants due to N-terminal acetyltransferase deficiency. Am J Hum Genet (2011) 3.43
A probabilistic disease-gene finder for personal genomes. Genome Res (2011) 3.23
A comprehensive map of mobile element insertion polymorphisms in humans. PLoS Genet (2011) 3.14
Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms. Genome Res (2003) 2.47
A comprehensive analysis of recently integrated human Ta L1 elements. Am J Hum Genet (2002) 2.47
De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. Nat Genet (2012) 2.34
Natural selection and molecular evolution in PTC, a bitter-taste receptor gene. Am J Hum Genet (2004) 2.33
Mutations in genes encoding fast-twitch contractile proteins cause distal arthrogryposis syndromes. Am J Hum Genet (2003) 2.11
Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proc Natl Acad Sci U S A (2008) 2.06
Maximum-likelihood estimation of recent shared ancestry (ERSA). Genome Res (2011) 1.88
Alu elements and hominid phylogenetics. Proc Natl Acad Sci U S A (2003) 1.81
A strong signature of balancing selection in the 5' cis-regulatory region of CCR5. Proc Natl Acad Sci U S A (2002) 1.78
Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications. Proc Natl Acad Sci U S A (2008) 1.70
Mobile element scanning (ME-Scan) identifies thousands of novel Alu insertions in diverse human populations. Genome Res (2013) 1.66
Larger genetic differences within africans than between Africans and Eurasians. Genetics (2002) 1.62
Natural selection and population history in the human angiotensinogen gene (AGT): 736 complete AGT sequences in chromosomes from around the world. Am J Hum Genet (2004) 1.61
A method for detecting recent selection in the human genome from allele age estimates. Genetics (2003) 1.55
Mobile element scanning (ME-Scan) by targeted high-throughput sequencing. BMC Genomics (2010) 1.54
Mutations in TNNT3 cause multiple congenital contractures: a second locus for distal arthrogryposis type 2B. Am J Hum Genet (2003) 1.52
Worldwide haplotype diversity and coding sequence variation at human bitter taste receptor loci. Hum Mutat (2005) 1.50
Fine-scaled human genetic structure revealed by SNP microarrays. Genome Res (2009) 1.48
Toward a more uniform sampling of human genetic diversity: a survey of worldwide populations by high-density genotyping. Genomics (2010) 1.47
Recently integrated Alu elements and human genomic diversity. Mol Biol Evol (2003) 1.46
Balinese Y-chromosome perspective on the peopling of Indonesia: genetic contributions from pre-neolithic hunter-gatherers, Austronesian farmers, and Indian traders. Hum Biol (2005) 1.45
AGT genetic variation, plasma AGT, and blood pressure: An analysis of the Utah Genetic Reference Project pedigrees. Am J Hypertens (2010) 1.43
Nucleotide diversity and haplotype structure of the human angiotensinogen gene in two populations. Am J Hum Genet (2001) 1.43
Insights into the demographic history of African Pygmies from complete mitochondrial genomes. Mol Biol Evol (2010) 1.43
Gene flow from the Indian subcontinent to Australia: evidence from the Y chromosome. Curr Biol (2002) 1.43
Mobile DNA elements in primate and human evolution. Am J Phys Anthropol (2007) 1.38
Genome-wide analysis of the human Alu Yb-lineage. Hum Genomics (2004) 1.33
A novel mutation in FGFR3 causes camptodactyly, tall stature, and hearing loss (CATSHL) syndrome. Am J Hum Genet (2006) 1.31
Common variants on chromosome 2 and risk of primary open-angle glaucoma in the Afro-Caribbean population of Barbados. Proc Natl Acad Sci U S A (2009) 1.30
Expressivity of Holt-Oram syndrome is not predicted by TBX5 genotype. Am J Hum Genet (2003) 1.26
Germline mutations in NFKB2 implicate the noncanonical NF-κB pathway in the pathogenesis of common variable immunodeficiency. Am J Hum Genet (2013) 1.23
Genetic determinants of Tibetan high-altitude adaptation. Hum Genet (2011) 1.21
Variants in TNFAIP3, STAT4, and C12orf30 loci associated with multiple autoimmune diseases are also associated with juvenile idiopathic arthritis. Arthritis Rheum (2009) 1.20
LINE-1 preTa elements in the human genome. J Mol Biol (2003) 1.16
HapMap tagSNP transferability in multiple populations: general guidelines. Genomics (2008) 1.16
Variation in the human TAS1R taste receptor genes. Chem Senses (2006) 1.14
Genetic diversity in India and the inference of Eurasian population expansion. Genome Biol (2010) 1.13
Alu repeats increase local recombination rates. BMC Genomics (2009) 1.11
Contrasting effects of natural selection on human and chimpanzee CC chemokine receptor 5. Am J Hum Genet (2004) 1.10
Directional migration in the Hindu castes: inferences from mitochondrial, autosomal and Y-chromosomal data. Hum Genet (2004) 1.09
Trismus-pseudocamptodactyly syndrome is caused by recurrent mutation of MYH8. Am J Med Genet A (2006) 1.08
Following the LINEs: an analysis of primate genomic variation at human-specific LINE-1 insertion sites. Mol Biol Evol (2003) 1.08
Affinities among Melanesians, Micronesians, and Polynesians: a neutral biparental genetic perspective. Hum Biol (2002) 1.07
Comprehensive analysis of two Alu Yd subfamilies. J Mol Evol (2003) 1.06
Mobile element biology: new possibilities with high-throughput sequencing. Trends Genet (2013) 1.05
Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol (2011) 1.03
Genetics and population history of Caucasus populations. Hum Biol (2003) 1.00
Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes. J Hypertens (2010) 0.97
Genomic analysis of natural selection and phenotypic variation in high-altitude mongolians. PLoS Genet (2013) 0.97
Comprehensive analysis of Alu-associated diversity on the human sex chromosomes. Gene (2003) 0.95
Mobile elements reveal small population size in the ancient ancestors of Homo sapiens. Proc Natl Acad Sci U S A (2010) 0.94
EWS/FLI-responsive GGAA microsatellites exhibit polymorphic differences between European and African populations. Cancer Genet (2012) 0.94
Metabolic insight into mechanisms of high-altitude adaptation in Tibetans. Mol Genet Metab (2012) 0.93
High fidelity of whole-genome amplified DNA on high-density single nucleotide polymorphism arrays. Genomics (2008) 0.93
Length polymorphism of thymidylate synthase regulatory region in Chinese populations and evolution of the novel alleles. Biochem Genet (2002) 0.91
Quantification of the familial contribution to juvenile idiopathic arthritis. Arthritis Rheum (2010) 0.89
Estimating the age of retrotransposon subfamilies using maximum likelihood. Genomics (2009) 0.89
The heritability of gestational age in a two-million member cohort: implications for spontaneous preterm birth. Hum Genet (2015) 0.89
Meta-analysis confirms association between TNFA-G238A variant and JIA, and between PTPN22-C1858T variant and oligoarticular, RF-polyarticular and RF-positive polyarticular JIA. Pediatr Rheumatol Online J (2013) 0.88
Hamartoma syndromes, exome sequencing, and a protean puzzle. N Engl J Med (2011) 0.86
Modeling the amplification dynamics of human Alu retrotransposons. PLoS Comput Biol (2005) 0.85
Genetic analysis of ancestry, admixture and selection in Bolivian and Totonac populations of the New World. BMC Genet (2012) 0.84
Genetic adaptation to extreme hypoxia: study of high-altitude pulmonary edema in a three-generation Han Chinese family. Blood Cells Mol Dis (2009) 0.84
Strong evidence for a novel schizophrenia risk locus on chromosome 1p31.1 in homogeneous pedigrees from Tamil Nadu, India. Am J Psychiatry (2008) 0.83
Limited distribution of a cardiomyopathy-associated variant in India. Ann Hum Genet (2010) 0.83
Temporal, seasonal, and regional differences in births and deaths in Aland (Finland). Hum Biol (2008) 0.83
Lack of association of functional CTLA4 polymorphisms with juvenile idiopathic arthritis. Arthritis Rheum (2008) 0.82
Effect of interleukin-6 polymorphism on risk of preterm birth within population strata: a meta-analysis. BMC Genet (2013) 0.81
Correction: Alternating Hemiplegia of Childhood: Retrospective Genetic Study and Genotype-Phenotype Correlations in 187 Subjects from the US AHCF Registry. PLoS One (2015) 0.81
Duplication and divergence in humans and chimpanzees. Bioessays (2006) 0.81
Culture creates genetic structure in the Caucasus: autosomal, mitochondrial, and Y-chromosomal variation in Daghestan. BMC Genet (2008) 0.80
Ancestry of the Iban is predominantly Southeast Asian: genetic evidence from autosomal, mitochondrial, and Y chromosomes. PLoS One (2011) 0.79
Ancestral alleles and population origins: inferences depend on mutation rate. Mol Biol Evol (2007) 0.78
Using VAAST to Identify Disease-Associated Variants in Next-Generation Sequencing Data. Curr Protoc Hum Genet (2014) 0.77