Published in Am J Psychiatry on October 15, 2010
Disruption of social approach by MK-801, amphetamine, and fluoxetine in adolescent C57BL/6J mice. Neurotoxicol Teratol (2012) 2.12
Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome. Proc Natl Acad Sci U S A (2014) 1.51
Chromosomal microarray analysis of consecutive individuals with autism spectrum disorders or learning disability presenting for genetic services. Gene (2013) 1.09
The FMRP regulon: from targets to disease convergence. Front Neurosci (2013) 1.07
Cellular and synaptic network defects in autism. Curr Opin Neurobiol (2012) 1.02
Glutamate receptor dysfunction and drug targets across models of autism spectrum disorders. Pharmacol Biochem Behav (2011) 1.01
Synaptic proteins and receptors defects in autism spectrum disorders. Front Cell Neurosci (2014) 0.98
PRICKLE1 interaction with SYNAPSIN I reveals a role in autism spectrum disorders. PLoS One (2013) 0.97
Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins. Front Mol Neurosci (2014) 0.96
Following the genes: a framework for animal modeling of psychiatric disorders. BMC Biol (2011) 0.94
Social brain development in williams syndrome: the current status and directions for future research. Front Psychol (2012) 0.93
A novel role for PSD-95 in mediating ethanol intoxication, drinking and place preference. Addict Biol (2011) 0.93
Unpredictable neonatal stress enhances adult anxiety and alters amygdala gene expression related to serotonin and GABA. Neuroscience (2013) 0.89
Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism. Behav Brain Res (2013) 0.88
Social phenotypes of autism spectrum disorders and williams syndrome: similarities and differences. Front Psychol (2012) 0.86
Modulation of behavior by scaffolding proteins of the post-synaptic density. Neurobiol Learn Mem (2013) 0.86
Expression of the G72/G30 gene in transgenic mice induces behavioral changes. Mol Psychiatry (2013) 0.86
Preweaning sensorimotor deficits and adolescent hypersociability in Grin1 knockdown mice. Dev Neurosci (2012) 0.84
Durable fear memories require PSD-95. Mol Psychiatry (2014) 0.84
Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability. Mol Cytogenet (2014) 0.83
Molecular handoffs in nitrergic neurotransmission. Front Med (Lausanne) (2014) 0.83
Characterisation of de novo MAPK10/JNK3 truncation mutations associated with cognitive disorders in two unrelated patients. Hum Genet (2013) 0.83
Individual differences in frontolimbic circuitry and anxiety emerge with adolescent changes in endocannabinoid signaling across species. Proc Natl Acad Sci U S A (2016) 0.82
Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome. Curr Opin Neurol (2012) 0.82
Altered microstructure within social-cognitive brain networks during childhood in Williams syndrome. Cereb Cortex (2013) 0.82
Brief report: altered social behavior in isolation-reared Fmr1 knockout mice. J Autism Dev Disord (2013) 0.80
Maternal Style Selectively Shapes Amygdalar Development and Social Behavior in Rats Genetically Prone to High Anxiety. Dev Neurosci (2015) 0.80
DPP6 gene disruption in a family with Gilles de la Tourette syndrome. Neurogenetics (2014) 0.79
Dehydroascorbic Acid Attenuates Ischemic Brain Edema and Neurotoxicity in Cerebral Ischemia: An in vivo Study. Exp Neurobiol (2015) 0.79
Using Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autism. BMC Bioinformatics (2015) 0.79
Tolerance to ethanol intoxication after chronic ethanol: role of GluN2A and PSD-95. Addict Biol (2014) 0.79
The SocioBox: A Novel Paradigm to Assess Complex Social Recognition in Male Mice. Front Behav Neurosci (2016) 0.79
The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity. Mol Brain (2016) 0.78
Autism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits. Mol Autism (2014) 0.78
The effects of aging on the BTBR mouse model of autism spectrum disorder. Front Aging Neurosci (2014) 0.78
Psychometric precision in phenotype definition is a useful step in molecular genetic investigation of psychiatric disorders. Transl Psychiatry (2015) 0.78
Glutamatergic candidate genes in autism spectrum disorder: an overview. J Neural Transm (Vienna) (2014) 0.78
Epistatic interaction of genetic depression risk variants in the human subgenual cingulate cortex during memory encoding. Transl Psychiatry (2014) 0.78
Effects of genetic deletion of the Kv4.2 voltage-gated potassium channel on murine anxiety-, fear- and stress-related behaviors. Biol Mood Anxiety Disord (2012) 0.77
FMRP: a triple threat to PSD-95. Front Cell Neurosci (2013) 0.77
Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders. Cell Syst (2015) 0.76
Reductions in synaptic proteins and selective alteration of prepulse inhibition in male C57BL/6 mice after postnatal administration of a VIP receptor (VIPR2) agonist. Psychopharmacology (Berl) (2015) 0.76
Resequencing and Association Analysis of Six PSD-95-Related Genes as Possible Susceptibility Genes for Schizophrenia and Autism Spectrum Disorders. Sci Rep (2016) 0.75
Emerging Synaptic Molecules as Candidates in the Etiology of Neurological Disorders. Neural Plast (2017) 0.75
The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila. Mol Cell Neurosci (2015) 0.75
Decreased anxiety- and depression-like behaviors and hyperactivity in a type 3 deiodinase-deficient mouse showing brain thyrotoxicosis and peripheral hypothyroidism. Psychoneuroendocrinology (2016) 0.75
A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function. Proc Natl Acad Sci U S A (2016) 0.75
NOMA-GAP/ARHGAP33 regulates synapse development and autistic-like behavior in the mouse. Mol Psychiatry (2015) 0.75
A Novel Human CAMK2A Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors. J Neurosci (2017) 0.75
Developing Medications Targeting Glutamatergic Dysfunction in Autism: Progress to Date. CNS Drugs (2015) 0.75
Magel2 knockout mice manifest altered social phenotypes and a deficit in preference for social novelty. Genes Brain Behav (2017) 0.75
Modulation of Synaptic Plasticity by Exercise Training as a Basis for Ischemic Stroke Rehabilitation. Cell Mol Neurobiol (2016) 0.75
Structural variation of chromosomes in autism spectrum disorder. Am J Hum Genet (2008) 15.51
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci (2005) 10.13
Neuroligins and neurexins link synaptic function to cognitive disease. Nature (2008) 9.23
PDZ domain proteins of synapses. Nat Rev Neurosci (2004) 8.14
Identifying autism loci and genes by tracing recent shared ancestry. Science (2008) 7.72
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science (2007) 6.64
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature (1998) 6.29
Supravalvular aortic stenosis. Circulation (1961) 5.45
Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci (2006) 3.92
Autism-like behavioral phenotypes in BTBR T+tf/J mice. Genes Brain Behav (2007) 3.76
Anatomical and physiological plasticity of dendritic spines. Annu Rev Neurosci (2007) 3.75
Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism. Proc Natl Acad Sci U S A (2008) 3.74
The amygdala response to emotional stimuli: a comparison of faces and scenes. Neuroimage (2002) 3.70
Classical and Bayesian inference in neuroimaging: theory. Neuroimage (2002) 3.56
Supravalvular aortic stenosis in association with mental retardation and a certain facial appearance. Circulation (1962) 3.11
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. Proc Natl Acad Sci U S A (2009) 2.93
Neural mechanisms of a genome-wide supported psychosis variant. Science (2009) 2.88
Immune transcriptome alterations in the temporal cortex of subjects with autism. Neurobiol Dis (2008) 2.88
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron (2004) 2.76
Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior. J Neurosci (2010) 2.57
Motor coordination in autism spectrum disorders: a synthesis and meta-analysis. J Autism Dev Disord (2010) 2.51
Designing mouse behavioral tasks relevant to autistic-like behaviors. Ment Retard Dev Disabil Res Rev (2004) 2.31
Smaller dendritic spines, weaker synaptic transmission, but enhanced spatial learning in mice lacking Shank1. J Neurosci (2008) 2.27
Neural mechanisms in Williams syndrome: a unique window to genetic influences on cognition and behaviour. Nat Rev Neurosci (2006) 2.13
Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. Neuropsychopharmacology (2009) 2.10
Synaptic regulation of protein synthesis and the fragile X protein. Proc Natl Acad Sci U S A (2001) 2.09
Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice. Autism Res (2008) 2.08
Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation. Am J Hum Genet (2004) 2.04
Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. J Neurosci (2000) 1.88
The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders. Trends Neurosci (2009) 1.84
Removal of FKBP12 enhances mTOR-Raptor interactions, LTP, memory, and perseverative/repetitive behavior. Neuron (2008) 1.80
Synapse-associated protein 102/dlgh3 couples the NMDA receptor to specific plasticity pathways and learning strategies. J Neurosci (2007) 1.68
Fragile X: translation in action. Neuropsychopharmacology (2007) 1.65
Defining the social phenotype in Williams syndrome: a model for linking gene, the brain, and behavior. Dev Psychopathol (2008) 1.61
Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit. Genes Brain Behav (2009) 1.51
Microanatomy of dendritic spines: emerging principles of synaptic pathology in psychiatric and neurological disease. Biol Psychiatry (2004) 1.45
Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice. EMBO Mol Med (2009) 1.30
Neurotransmitters drive combinatorial multistate postsynaptic density networks. Sci Signal (2009) 1.24
Association of Per1 and Npas2 with autistic disorder: support for the clock genes/social timing hypothesis. Mol Psychiatry (2007) 1.20
LIMK1 and CLIP-115: linking cytoskeletal defects to Williams syndrome. Bioessays (2004) 1.11
Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry. Brain Res (2006) 1.07
mGlu5 receptor antagonists: a novel class of anxiolytics? Drug News Perspect (2004) 0.91
Satellites on the terminal short arm of chromosome 12 (12ps), inherited through several generations in three families: a new variant without phenotypic effect. J Med Genet (2001) 0.77
Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13
The HUPO PSI's molecular interaction format--a community standard for the representation of protein interaction data. Nat Biotechnol (2004) 16.08
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52
Common variants conferring risk of schizophrenia. Nature (2009) 10.37
5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci (2005) 10.13
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34
Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am J Psychiatry (2010) 6.15
Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13
City living and urban upbringing affect neural social stress processing in humans. Nature (2011) 5.46
Oxytocin modulates neural circuitry for social cognition and fear in humans. J Neurosci (2005) 5.42
Hierarchical organization of human cortical networks in health and schizophrenia. J Neurosci (2008) 5.19
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine. Nat Rev Neurosci (2011) 5.03
A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94
The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology. J Neurosci (2004) 4.84
Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron (2006) 4.80
Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78
Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry (2009) 4.74
Adaptive reconfiguration of fractal small-world human brain functional networks. Proc Natl Acad Sci U S A (2006) 4.58
Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38
Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat Neurosci (2005) 4.00
Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogn Sci (2006) 3.92
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
The ascent of mouse: advances in modelling human depression and anxiety. Nat Rev Drug Discov (2005) 3.80
Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73
Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome. J Neurochem (2006) 3.67
Characterization of the proteome, diseases and evolution of the human postsynaptic density. Nat Neurosci (2010) 3.67
Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet (2009) 3.58
PDZ domain proteins: plug and play! Sci STKE (2003) 3.38
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24
High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02
Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. Nat Genet (2009) 2.93
Know your place: neural processing of social hierarchy in humans. Neuron (2008) 2.92
Neural mechanisms of a genome-wide supported psychosis variant. Science (2009) 2.88
Impaired fear extinction learning and cortico-amygdala circuit abnormalities in a common genetic mouse strain. J Neurosci (2008) 2.87
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron (2004) 2.76
Single nucleotide variation analysis in 65 candidate genes for CNS disorders in a representative sample of the European population. Genome Res (2003) 2.75
Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient. Biol Psychiatry (2010) 2.71
Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet (2011) 2.71
Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia. Proc Natl Acad Sci U S A (2005) 2.68
Brief uncontrollable stress causes dendritic retraction in infralimbic cortex and resistance to fear extinction in mice. J Neurosci (2006) 2.68
Why New Zealand must rapidly halve its greenhouse gas emissions. N Z Med J (2009) 2.67
Dissecting the phenotype in genome-wide association studies of psychiatric illness. Br J Psychiatry (2009) 2.65
A validated network of effective amygdala connectivity. Neuroimage (2007) 2.58
A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability. Nat Neurosci (2007) 2.54
Prediction error as a linear function of reward probability is coded in human nucleus accumbens. Neuroimage (2006) 2.52
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. Genes Dev (2004) 2.49
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J Neurosci (2002) 2.46
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1. Nat Genet (2010) 2.46
Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy. Nat Rev Drug Discov (2012) 2.44
Genome-wide pharmacogenetics of antidepressant response in the GENDEP project. Am J Psychiatry (2010) 2.41
Efficient physical embedding of topologically complex information processing networks in brains and computer circuits. PLoS Comput Biol (2010) 2.37
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nat Med (2009) 2.37
Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet (2011) 2.21
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. BMC Med Genomics (2008) 2.20
Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol (2009) 2.17
A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function. Proc Natl Acad Sci U S A (2010) 2.16
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci. Nat Genet (2012) 2.15
Cognitive fitness of cost-efficient brain functional networks. Proc Natl Acad Sci U S A (2009) 2.07
Neurophysiological correlates of age-related changes in working memory capacity. Neurosci Lett (2005) 2.06
The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes. J Physiol (2002) 2.05
TIGAR is required for efficient intestinal regeneration and tumorigenesis. Dev Cell (2013) 2.03
Test-retest reliability of resting-state connectivity network characteristics using fMRI and graph theoretical measures. Neuroimage (2011) 2.03
The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron (2011) 2.02
Interacting effects of the dopamine transporter gene and psychosocial adversity on attention-deficit/hyperactivity disorder symptoms among 15-year-olds from a high-risk community sample. Arch Gen Psychiatry (2007) 2.02
Effects of repeated maternal separation on anxiety- and depression-related phenotypes in different mouse strains. Neurosci Biobehav Rev (2006) 2.00
Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Am J Hum Genet (2002) 1.99
Proteomic analysis of in vivo phosphorylated synaptic proteins. J Biol Chem (2004) 1.99