Published in Proc Natl Acad Sci U S A on October 18, 2010
Alternative splicing at the intersection of biological timing, development, and stress responses. Plant Cell (2013) 2.63
Alternative splicing mediates responses of the Arabidopsis circadian clock to temperature changes. Plant Cell (2012) 1.74
Complexity in the wiring and regulation of plant circadian networks. Curr Biol (2012) 1.58
Versatility of PRMT5-induced methylation in growth control and development. Trends Biochem Sci (2011) 1.44
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery. Genes Dev (2013) 1.27
SKIP is a component of the spliceosome linking alternative splicing and the circadian clock in Arabidopsis. Plant Cell (2012) 1.21
Structural insights into protein arginine symmetric dimethylation by PRMT5. Proc Natl Acad Sci U S A (2011) 1.14
Arabidopsis floral initiator SKB1 confers high salt tolerance by regulating transcription and pre-mRNA splicing through altering histone H4R3 and small nuclear ribonucleoprotein LSM4 methylation. Plant Cell (2011) 1.11
PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145. Nat Commun (2015) 1.04
NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis. Plant Cell (2013) 1.02
Polypyrimidine tract binding protein homologs from Arabidopsis are key regulators of alternative splicing with implications in fundamental developmental processes. Plant Cell (2012) 1.01
An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana. Nucleic Acids Res (2012) 1.00
The Role of Protein Arginine Methylation in mRNP Dynamics. Mol Biol Int (2011) 0.98
A functional component of the transcriptionally active chromosome complex, Arabidopsis pTAC14, interacts with pTAC12/HEMERA and regulates plastid gene expression. Plant Physiol (2011) 0.95
A KH-domain RNA-binding protein interacts with FIERY2/CTD phosphatase-like 1 and splicing factors and is important for pre-mRNA splicing in Arabidopsis. PLoS Genet (2013) 0.94
Escape from preferential retention following repeated whole genome duplications in plants. Front Plant Sci (2012) 0.94
LSM proteins provide accurate splicing and decay of selected transcripts to ensure normal Arabidopsis development. Plant Cell (2012) 0.94
Alternative splicing adds a new loop to the circadian clock. Commun Integr Biol (2011) 0.91
The spliceosome-activating complex: molecular mechanisms underlying the function of a pleiotropic regulator. Front Plant Sci (2012) 0.90
The cyclophilin CYP20-2 modulates the conformation of BRASSINAZOLE-RESISTANT1, which binds the promoter of FLOWERING LOCUS D to regulate flowering in Arabidopsis. Plant Cell (2013) 0.90
The Role of Polypyrimidine Tract-Binding Proteins and Other hnRNP Proteins in Plant Splicing Regulation. Front Plant Sci (2012) 0.90
Role of chromatin in water stress responses in plants. J Exp Bot (2013) 0.89
Small Molecule Inhibitors of Protein Arginine Methyltransferases. Expert Opin Investig Drugs (2016) 0.89
Crystal structure of the plant epigenetic protein arginine methyltransferase 10. J Mol Biol (2011) 0.88
Integrating circadian dynamics with physiological processes in plants. Nat Rev Genet (2015) 0.88
New approaches to Prunus transcriptome analysis. Genetica (2011) 0.88
Circadian clock and photoperiodic response in Arabidopsis: from seasonal flowering to redox homeostasis. Biochemistry (2014) 0.86
Arabidopsis protein arginine methyltransferase 3 is required for ribosome biogenesis by affecting precursor ribosomal RNA processing. Proc Natl Acad Sci U S A (2014) 0.85
The circadian clock goes genomic. Genome Biol (2013) 0.85
Genome wide comparative analysis of the effects of PRMT5 and PRMT4/CARM1 arginine methyltransferases on the Arabidopsis thaliana transcriptome. BMC Genomics (2015) 0.81
RNA around the clock - regulation at the RNA level in biological timing. Front Plant Sci (2015) 0.80
Alternative splicing at the right time. RNA Biol (2011) 0.80
Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process. Biomolecules (2015) 0.80
Arabidopsis histone methylase CAU1/PRMT5/SKB1 acts as an epigenetic suppressor of the calcium signaling gene CAS to mediate stomatal closure in response to extracellular calcium. Plant Cell (2013) 0.79
Characterization of the PRMT gene family in rice reveals conservation of arginine methylation. PLoS One (2011) 0.79
Proteomic Analysis of a Fraction with Intact Eyespots of Chlamydomonas reinhardtii and Assignment of Protein Methylation. Front Plant Sci (2015) 0.78
The enzymatic activity of Arabidopsis protein arginine methyltransferase 10 is essential for flowering time regulation. Protein Cell (2012) 0.78
Histone H4R3 methylation catalyzed by SKB1/PRMT5 is required for maintaining shoot apical meristem. PLoS One (2013) 0.77
RNA Binding Proteins RZ-1B and RZ-1C Play Critical Roles in Regulating Pre-mRNA Splicing and Gene Expression during Development in Arabidopsis. Plant Cell (2015) 0.77
Recruitment of the NineTeen Complex to the activated spliceosome requires AtPRMT5. Proc Natl Acad Sci U S A (2016) 0.76
The regulatory role of Pcf11-similar-4 (PCFS4) in Arabidopsis development by genome-wide physical interactions with target loci. BMC Genomics (2013) 0.76
Unraveling the circadian clock in Arabidopsis. Plant Signal Behav (2012) 0.76
JACALIN-LECTIN LIKE1 Regulates the Nuclear Accumulation of GLYCINE-RICH RNA-BINDING PROTEIN7, Influencing the RNA Processing of FLOWERING LOCUS C Antisense Transcripts and Flowering Time in Arabidopsis. Plant Physiol (2015) 0.76
TDRD6 mediates early steps of spliceosome maturation in primary spermatocytes. PLoS Genet (2017) 0.75
Role of type II protein arginine methyltransferase 5 in the regulation of Circadian Per1 gene. PLoS One (2012) 0.75
Root morphogenic pathways in Eucalyptus grandis are modified by the activity of protein arginine methyltransferases. BMC Plant Biol (2017) 0.75
PRMT5 regulates IRES-dependent translation via methylation of hnRNP A1. Nucleic Acids Res (2017) 0.75
Role of protein arginine methyltransferase 5 in inflammation and migration of fibroblast-like synoviocytes in rheumatoid arthritis. J Cell Mol Med (2016) 0.75
Investment in plant research and development bears fruit in China. Plant Cell Rep (2014) 0.75
Alternative Splicing in Plant Genes: A Means of Regulating the Environmental Fitness of Plants. Int J Mol Sci (2017) 0.75
Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol (2009) 235.12
Mapping and quantifying mammalian transcriptomes by RNA-Seq. Nat Methods (2008) 126.81
Regulation of alternative splicing by histone modifications. Science (2010) 7.98
Protein arginine methylation in mammals: who, what, and why. Mol Cell (2009) 7.44
Splicing in disease: disruption of the splicing code and the decoding machinery. Nat Rev Genet (2007) 7.42
GOEAST: a web-based software toolkit for Gene Ontology enrichment analysis. Nucleic Acids Res (2008) 6.91
Arginine methylation an emerging regulator of protein function. Mol Cell (2005) 6.49
Genome-wide mapping of alternative splicing in Arabidopsis thaliana. Genome Res (2009) 5.24
SMN deficiency causes tissue-specific perturbations in the repertoire of snRNAs and widespread defects in splicing. Cell (2008) 4.54
Blimp1 associates with Prmt5 and directs histone arginine methylation in mouse germ cells. Nat Cell Biol (2006) 3.65
The methylosome, a 20S complex containing JBP1 and pICln, produces dimethylarginine-modified Sm proteins. Mol Cell Biol (2001) 3.27
Alternative splicing of pre-messenger RNAs in plants in the genomic era. Annu Rev Plant Biol (2007) 3.09
SMN, the product of the spinal muscular atrophy gene, binds preferentially to dimethylarginine-containing protein targets. Mol Cell (2001) 2.95
Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes Dev (2009) 2.95
Arginine methylation regulates the p53 response. Nat Cell Biol (2008) 2.94
Methylation of Sm proteins by a complex containing PRMT5 and the putative U snRNP assembly factor pICln. Curr Biol (2001) 2.90
Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2008) 2.74
A proteomic analysis of arginine-methylated protein complexes. Mol Cell Proteomics (2003) 2.59
In vivo and in vitro arginine methylation of RNA-binding proteins. Mol Cell Biol (1995) 2.55
Tudor domains bind symmetrical dimethylated arginines. J Biol Chem (2005) 2.23
A novel WD repeat protein component of the methylosome binds Sm proteins. J Biol Chem (2001) 2.22
Histone methylation in higher plants. Annu Rev Plant Biol (2010) 2.13
Assisted RNP assembly: SMN and PRMT5 complexes cooperate in the formation of spliceosomal UsnRNPs. EMBO J (2002) 2.04
SERRATE coordinates shoot meristem function and leaf axial patterning in Arabidopsis. Nature (2005) 2.01
Symmetrical dimethylarginine methylation is required for the localization of SMN in Cajal bodies and pre-mRNA splicing. J Cell Biol (2002) 1.83
atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes. Genes Dev (1999) 1.82
The Sm-protein methyltransferase, dart5, is essential for germ-cell specification and maintenance. Curr Biol (2006) 1.78
Regulation of flowering time in Arabidopsis by K homology domain proteins. Proc Natl Acad Sci U S A (2004) 1.73
An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Cell (2008) 1.72
Arginine methyltransferase Capsuleen is essential for methylation of spliceosomal Sm proteins and germ cell formation in Drosophila. Development (2007) 1.61
A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C. Plant Cell (2004) 1.56
Deciphering the assembly pathway of Sm-class U snRNPs. FEBS Lett (2008) 1.55
The ASRG database: identification and survey of Arabidopsis thaliana genes involved in pre-mRNA splicing. Genome Biol (2004) 1.51
Two RNA binding proteins, HEN4 and HUA1, act in the processing of AGAMOUS pre-mRNA in Arabidopsis thaliana. Dev Cell (2003) 1.47
Commitment of yeast pre-mRNA to the splicing pathway requires a novel U1 small nuclear ribonucleoprotein polypeptide, Prp39p. Mol Cell Biol (1994) 1.44
Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis. Nucleic Acids Res (2008) 1.43
Methylation of ribosomal protein S10 by protein-arginine methyltransferase 5 regulates ribosome biogenesis. J Biol Chem (2010) 1.37
SKB1-mediated symmetric dimethylation of histone H4R3 controls flowering time in Arabidopsis. EMBO J (2007) 1.37
Identification of proteins interacting with the RNAPII FCP1 phosphatase: FCP1 forms a complex with arginine methyltransferase PRMT5 and it is a substrate for PRMT5-mediated methylation. FEBS Lett (2005) 1.32
Histone arginine methylation is required for vernalization-induced epigenetic silencing of FLC in winter-annual Arabidopsis thaliana. Proc Natl Acad Sci U S A (2008) 1.22
Mutations in the Type II protein arginine methyltransferase AtPRMT5 result in pleiotropic developmental defects in Arabidopsis. Plant Physiol (2007) 1.22
HUA2 is required for the expression of floral repressors in Arabidopsis thaliana. Plant J (2005) 1.20
PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Res (2010) 1.05
Regulation of flowering time by the protein arginine methyltransferase AtPRMT10. EMBO Rep (2007) 1.01
Caenorhabditis elegans protein arginine methyltransferase PRMT-5 negatively regulates DNA damage-induced apoptosis. PLoS Genet (2009) 1.00
Post-translational modifications, but not transcriptional regulation, of major chloroplast RNA-binding proteins are related to Arabidopsis seedling development. Proteomics (2006) 0.97
Regulation of flowering time by RNA processing. Curr Top Microbiol Immunol (2008) 0.94
The Arabidopsis thaliana AT PRP39-1 gene, encoding a tetratricopeptide repeat protein with similarity to the yeast pre-mRNA processing protein PRP39, affects flowering time. Plant Cell Rep (2007) 0.88
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
ARGONAUTE4 control of locus-specific siRNA accumulation and DNA and histone methylation. Science (2003) 9.54
Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase. Nature (2002) 9.51
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Criteria for annotation of plant MicroRNAs. Plant Cell (2008) 7.49
Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification. Cell (2011) 5.27
A genetic variation map for chicken with 2.8 million single-nucleotide polymorphisms. Nature (2004) 5.24
One-way control of FWA imprinting in Arabidopsis endosperm by DNA methylation. Science (2003) 5.00
Interplay between two epigenetic marks. DNA methylation and histone H3 lysine 9 methylation. Curr Biol (2002) 4.98
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility. Mol Cell (2012) 4.18
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Role of Arabidopsis ARGONAUTE4 in RNA-directed DNA methylation triggered by inverted repeats. Curr Biol (2004) 3.54
Deep RNA sequencing at single base-pair resolution reveals high complexity of the rice transcriptome. Genome Res (2010) 3.34
Genome-wide analysis for discovery of rice microRNAs reveals natural antisense microRNAs (nat-miRNAs). Proc Natl Acad Sci U S A (2008) 2.92
The first identification of lysine malonylation substrates and its regulatory enzyme. Mol Cell Proteomics (2011) 2.83
A complete sequence of the T. tengcongensis genome. Genome Res (2002) 2.60
HMGB1 mediates endogenous TLR2 activation and brain tumor regression. PLoS Med (2009) 2.56
Pigs in sequence space: a 0.66X coverage pig genome survey based on shotgun sequencing. BMC Genomics (2005) 2.34
MicroRNAs inhibit the translation of target mRNAs on the endoplasmic reticulum in Arabidopsis. Cell (2013) 2.28
The genome sequence of Salmonella enterica serovar Choleraesuis, a highly invasive and resistant zoonotic pathogen. Nucleic Acids Res (2005) 2.21
Histone methylation in higher plants. Annu Rev Plant Biol (2010) 2.13
High rate of chimeric gene origination by retroposition in plant genomes. Plant Cell (2006) 2.08
On the nature of human housekeeping genes. Trends Genet (2008) 2.06
Decoupling suspension controller based on magnetic flux feedback. ScientificWorldJournal (2013) 2.03
EvolView, an online tool for visualizing, annotating and managing phylogenetic trees. Nucleic Acids Res (2012) 1.90
A comparison of rice chloroplast genomes. Plant Physiol (2004) 1.85
Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing. Carcinogenesis (2012) 1.84
The Putative RNA-dependent RNA polymerase RDR6 acts synergistically with ASYMMETRIC LEAVES1 and 2 to repress BREVIPEDICELLUS and MicroRNA165/166 in Arabidopsis leaf development. Plant Cell (2005) 1.80
Loss of function of OsDCL1 affects microRNA accumulation and causes developmental defects in rice. Plant Physiol (2005) 1.77
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model. Cancer Res (2005) 1.74
Arabidopsis REF6 is a histone H3 lysine 27 demethylase. Nat Genet (2011) 1.74
Brain edema after intracerebral hemorrhage in rats: the role of inflammation. Neurol India (2006) 1.69
A transcriptomic analysis of superhybrid rice LYP9 and its parents. Proc Natl Acad Sci U S A (2009) 1.67
Wild bird migration across the Qinghai-Tibetan plateau: a transmission route for highly pathogenic H5N1. PLoS One (2011) 1.62
The rice mitochondrial genomes and their variations. Plant Physiol (2005) 1.59
A brief review on the mechanisms of miRNA regulation. Genomics Proteomics Bioinformatics (2009) 1.56
Evolution and pathogenesis of Staphylococcus aureus: lessons learned from genotyping and comparative genomics. FEMS Microbiol Rev (2007) 1.55
The relationship of hamstrings and quadriceps strength to anterior cruciate ligament injury in female athletes. Clin J Sport Med (2009) 1.55
Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Mol Cell Proteomics (2012) 1.54
In vivo mature immunological synapses forming SMACs mediate clearance of virally infected astrocytes from the brain. J Exp Med (2006) 1.52
Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials. PLoS One (2008) 1.49
The silkworm (Bombyx mori) microRNAs and their expressions in multiple developmental stages. PLoS One (2008) 1.48
Complete genome sequence of bacteriophage T5. Virology (2005) 1.48
A comparison between ribo-minus RNA-sequencing and polyA-selected RNA-sequencing. Genomics (2010) 1.47
Hysteroscopic surgery of ectopic pregnancy in the cesarean section scar. J Minim Invasive Gynecol (2009) 1.46
Plasmid-mediated quinolone resistance determinants qnr and aac(6')-Ib-cr in extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in China. J Antimicrob Chemother (2008) 1.46
Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer. PLoS One (2009) 1.45
Small RNA-directed epigenetic natural variation in Arabidopsis thaliana. PLoS Genet (2008) 1.43
Inflammatory and anti-glioma effects of an adenovirus expressing human soluble Fms-like tyrosine kinase 3 ligand (hsFlt3L): treatment with hsFlt3L inhibits intracranial glioma progression. Mol Ther (2004) 1.42
Roles of DCL4 and DCL3b in rice phased small RNA biogenesis. Plant J (2011) 1.42
Regulatable gutless adenovirus vectors sustain inducible transgene expression in the brain in the presence of an immune response against adenoviruses. J Virol (2006) 1.41
Single-base resolution maps of cultivated and wild rice methylomes and regulatory roles of DNA methylation in plant gene expression. BMC Genomics (2012) 1.40
Genomic analysis of the multidrug-resistant Acinetobacter baumannii strain MDR-ZJ06 widely spread in China. Antimicrob Agents Chemother (2011) 1.40
ARGONAUTE10 and ARGONAUTE1 regulate the termination of floral stem cells through two microRNAs in Arabidopsis. PLoS Genet (2011) 1.40
SDG714, a histone H3K9 methyltransferase, is involved in Tos17 DNA methylation and transposition in rice. Plant Cell (2007) 1.39
Porcine transcriptome analysis based on 97 non-normalized cDNA libraries and assembly of 1,021,891 expressed sequence tags. Genome Biol (2007) 1.39
Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3. PLoS One (2008) 1.38
One-year expression from high-capacity adenoviral vectors in the brains of animals with pre-existing anti-adenoviral immunity: clinical implications. Mol Ther (2007) 1.36
Genome sequence of the date palm Phoenix dactylifera L. Nat Commun (2013) 1.35
Comparative analysis of JmjC domain-containing proteins reveals the potential histone demethylases in Arabidopsis and rice. J Integr Plant Biol (2008) 1.35
Fms-like tyrosine kinase 3 ligand recruits plasmacytoid dendritic cells to the brain. J Immunol (2006) 1.32
Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model. Neuro Oncol (2007) 1.31
Genome evolution driven by host adaptations results in a more virulent and antimicrobial-resistant Streptococcus pneumoniae serotype 14. BMC Genomics (2009) 1.31
Oryza sativa dicer-like4 reveals a key role for small interfering RNA silencing in plant development. Plant Cell (2007) 1.30
Identification and expression analysis of miRNAs from nitrogen-fixing soybean nodules. Biochem Biophys Res Commun (2008) 1.30
Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proc Natl Acad Sci U S A (2010) 1.29
Improved distribution of small molecules and viral vectors in the murine brain using a hollow fiber catheter. J Neurosurg (2007) 1.24
Transcriptome and expression profiling analysis revealed changes of multiple signaling pathways involved in immunity in the large yellow croaker during Aeromonas hydrophila infection. BMC Genomics (2010) 1.23
Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome. EMBO J (2010) 1.23
Release of HMGB1 in response to proapoptotic glioma killing strategies: efficacy and neurotoxicity. Clin Cancer Res (2009) 1.22
Mutations in the Type II protein arginine methyltransferase AtPRMT5 result in pleiotropic developmental defects in Arabidopsis. Plant Physiol (2007) 1.22
Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma. Cancer Res (2006) 1.22
AGAMOUS terminates floral stem cell maintenance in Arabidopsis by directly repressing WUSCHEL through recruitment of Polycomb Group proteins. Plant Cell (2011) 1.22
A genome-wide microsatellite polymorphism database for the indica and japonica rice. DNA Res (2007) 1.21
The survey of H5N1 flu virus in wild birds in 14 Provinces of China from 2004 to 2007. PLoS One (2009) 1.21
Complete genome sequence of the pathogenic bacterium Riemerella anatipestifer strain RA-GD. J Bacteriol (2011) 1.20
Complete genome sequence of the metabolically versatile halophilic archaeon Haloferax mediterranei, a poly(3-hydroxybutyrate-co-3-hydroxyvalerate) producer. J Bacteriol (2012) 1.19
High-resolution N(6) -methyladenosine (m(6) A) map using photo-crosslinking-assisted m(6) A sequencing. Angew Chem Int Ed Engl (2014) 1.18
Identification of lysine succinylation substrates and the succinylation regulatory enzyme CobB in Escherichia coli. Mol Cell Proteomics (2013) 1.17
wapRNA: a web-based application for the processing of RNA sequences. Bioinformatics (2011) 1.17
Hydrogen sulfide improves drought resistance in Arabidopsis thaliana. Biochem Biophys Res Commun (2011) 1.17
Special fasciculiform cataract caused by a mutation in the gammaD-crystallin gene. Mol Vis (2004) 1.17
JMJ14 is an H3K4 demethylase regulating flowering time in Arabidopsis. Cell Res (2010) 1.17