Published in Cancer Lett on October 23, 2010
Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers. Gastroenterology (2011) 2.33
Does the hepatitis B antigen HBx promote the appearance of liver cancer stem cells? Cancer Res (2011) 1.33
Hepatitis B virus infection and the risk of hepatocellular carcinoma. World J Gastroenterol (2011) 1.14
Hepatitis B virus X protein accelerates the development of hepatoma. Cancer Biol Med (2014) 1.04
Virus associated malignancies: the role of viral hepatitis in hepatocellular carcinoma. Semin Cancer Biol (2014) 1.04
HBx-related long non-coding RNA DBH-AS1 promotes cell proliferation and survival by activating MAPK signaling in hepatocellular carcinoma. Oncotarget (2015) 0.99
Dickkopfs and Wnt/β-catenin signalling in liver cancer. World J Clin Oncol (2011) 0.94
Helicobacter pylori virulence factor CagA promotes tumorigenesis of gastric cancer via multiple signaling pathways. Cell Commun Signal (2015) 0.92
The hepatitis B virus-associated tumor microenvironment in hepatocellular carcinoma. Natl Sci Rev (2014) 0.91
Human tumour viruses and the deregulation of cell polarity in cancer. Nat Rev Cancer (2012) 0.90
Flavonoids and Wnt/β-catenin signaling: potential role in colorectal cancer therapies. Int J Mol Sci (2014) 0.89
Molecular alterations in hepatocellular carcinoma associated with hepatitis B and hepatitis C infections. Oncotarget (2016) 0.88
Novel strategies targeting cancer stem cells through phytochemicals and their analogs. Drug Deliv Transl Res (2013) 0.85
Structural and functional hepatocyte polarity and liver disease. J Hepatol (2015) 0.84
Curcumin a potent cancer preventive agent: Mechanisms of cancer cell killing. Interv Med Appl Sci (2014) 0.83
Hepatitis B virus and microRNAs: Complex interactions affecting hepatitis B virus replication and hepatitis B virus-associated diseases. World J Gastroenterol (2015) 0.81
Molecular mechanism of hepatitis B virus X protein function in hepatocarcinogenesis. World J Gastroenterol (2015) 0.80
Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol (2015) 0.78
Activation of signal transduction pathways during hepatic oncogenesis. Cancer Lett (2015) 0.77
The viral transactivator HBx protein exhibits a high potential for regulation via phosphorylation through an evolutionarily conserved mechanism. Infect Agent Cancer (2012) 0.77
Aberrant regulation of Wnt signaling in hepatocellular carcinoma. World J Gastroenterol (2016) 0.76
A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection. J Virol (2016) 0.76
Up-regulation of human cervical cancer proto-oncogene contributes to hepatitis B virus-induced malignant transformation of hepatocyte by down-regulating E-cadherin. Oncotarget (2015) 0.75
Study of Dickkopf-1 (DKK-1) Gene Expression in Hepatocellular Carcinoma Patients. J Clin Diagn Res (2017) 0.75
Chronic hepatitis infection is associated with extrahepatic cancer development: a nationwide population-based study in Taiwan. BMC Cancer (2016) 0.75
Hepatitis B virus molecular biology and pathogenesis. Hepatoma Res (2016) 0.75
Association of TIP30 expression and prognosis of hepatocellular carcinoma in patients with HBV infection. Cancer Med (2016) 0.75
HBx mutations promote hepatoma cell migration through the Wnt/β-catenin signaling pathway. Cancer Sci (2016) 0.75
The regulation of proteins associated with the cytoskeleton by hepatitis B virus X protein during hepatocarcinogenesis. Oncol Lett (2017) 0.75
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell (2010) 3.82
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature (2013) 2.67
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature (2005) 2.29
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood (2003) 2.05
Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1. Cancer Res (2012) 1.97
Epigenetic changes induced by reactive oxygen species in hepatocellular carcinoma: methylation of the E-cadherin promoter. Gastroenterology (2008) 1.78
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene. Blood (2011) 1.73
Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology (2007) 1.45
CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. J Clin Invest (2010) 1.41
Oxidative stress and antioxidants in hepatic pathogenesis. World J Gastroenterol (2010) 1.40
Comparison of proteome between hepatitis B virus- and hepatitis C virus-associated hepatocellular carcinoma. Clin Cancer Res (2003) 1.33
VDUP1 is required for the development of natural killer cells. Immunity (2005) 1.31
Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis. J Hepatol (2010) 1.30
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway. J Biol Chem (2003) 1.29
Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1alpha. FASEB J (2003) 1.25
Characterization of neural cell types expressing peroxiredoxins in mouse brain. Neurosci Lett (2005) 1.25
Proteome analysis of hepatocellular carcinoma. Biochem Biophys Res Commun (2002) 1.23
Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA. J Immunol Methods (2008) 1.18
Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock. J Exp Med (2007) 1.16
Up-regulation of cyclin D1 by HBx is mediated by NF-kappaB2/BCL3 complex through kappaB site of cyclin D1 promoter. J Biol Chem (2006) 1.15
Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha. J Biol Chem (2003) 1.14
p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma. FEBS Lett (2010) 1.11
Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. Circ Res (2011) 1.08
Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface. Proteins (2007) 1.07
Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation. Mol Endocrinol (2003) 1.06
Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter. FEBS Lett (2010) 1.05
Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis. J Hepatol (2009) 1.05
Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver. Hepatology (2011) 1.05
Peroxiredoxin II is an essential antioxidant enzyme that prevents the oxidative inactivation of VEGF receptor-2 in vascular endothelial cells. Mol Cell (2011) 1.05
Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J Pathol (2009) 1.04
Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches. Int J Oncol (2009) 1.04
Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma. Hepatology (2011) 1.04
The influence of the signal dynamics of activated form of IKK on NF-kappaB and anti-apoptotic gene expressions: a systems biology approach. FEBS Lett (2006) 1.03
Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase. Mol Cell Biol (2006) 1.00
Calcium ions affect the hepatitis B virus core assembly. Virology (2005) 0.99
Inhibitory role of peroxiredoxin II (Prx II) on cellular senescence. FEBS Lett (2005) 0.99
Gender-dependent hepatic alterations in H-ras12V transgenic mice. J Hepatol (2005) 0.98
The effects of disruption of genes for peroxiredoxin-2, glutathione peroxidase-1, and catalase on erythrocyte oxidative metabolism. Free Radic Biol Med (2009) 0.96
Phosphorylation of hepatitis B virus Cp at Ser87 facilitates core assembly. Biochem J (2006) 0.96
Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein. Cancer Res (2012) 0.96
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn. EMBO J (2009) 0.95
Asialoglycoprotein receptor targeted gene delivery using galactosylated polyethylenimine-graft-poly(ethylene glycol): in vitro and in vivo studies. J Control Release (2005) 0.95
HBx-induced hepatic steatosis and apoptosis are regulated by TNFR1- and NF-kappaB-dependent pathways. J Mol Biol (2010) 0.94
T lymphocytes and dendritic cells are activated by the deletion of peroxiredoxin II (Prx II) gene. Immunol Lett (2005) 0.94
Reactive oxygen species induced by the deletion of peroxiredoxin II (PrxII) increases the number of thymocytes resulting in the enlargement of PrxII-null thymus. Eur J Immunol (2004) 0.94
Antisense oligodeoxynucleotides targeted against molecular chaperonin Hsp60 block human hepatitis B virus replication. J Biol Chem (2003) 0.94
Hepatitis B virus X protein induced expression of interleukin 18 (IL-18): a potential mechanism for liver injury caused by hepatitis B virus (HBV) infection. J Hepatol (2002) 0.94
The hepatitis B viral X protein activates NF-kappaB signaling pathway through the up-regulation of TBK1. FEBS Lett (2009) 0.94
Hepatitis B virus X protein modulates peroxisome proliferator-activated receptor gamma through protein-protein interaction. FEBS Lett (2004) 0.92
Proteome analysis of human amnion and amniotic fluid by two-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proteomics (2006) 0.92
Gd-DOTA conjugate of RGD as a potential tumor-targeting MRI contrast agent. Chembiochem (2008) 0.92
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1. Bioorg Med Chem (2013) 0.91
Peroxiredoxin I is a ROS/p38 MAPK-dependent inducible antioxidant that regulates NF-κB-mediated iNOS induction and microglial activation. J Neuroimmunol (2013) 0.90
Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence. Free Radic Res (2006) 0.90
A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion. FEBS J (2008) 0.90
Peroxiredoxin II is essential for preventing hemolytic anemia from oxidative stress through maintaining hemoglobin stability. Biochem Biophys Res Commun (2012) 0.90
Notch1 binds and induces degradation of Snail in hepatocellular carcinoma. BMC Biol (2011) 0.89
HBx-induced reactive oxygen species activates hepatocellular carcinogenesis via dysregulation of PTEN/Akt pathway. World J Gastroenterol (2010) 0.89
Microglial peroxiredoxin V acts as an inducible anti-inflammatory antioxidant through cooperation with redox signaling cascades. J Neurochem (2010) 0.88
Human lactoferrin activates transcription of IL-1beta gene in mammalian cells. Biochem Biophys Res Commun (2002) 0.88
Proteomic analysis of liver tissue from HBx-transgenic mice at early stages of hepatocarcinogenesis. Proteomics (2009) 0.87
Up-regulation of Foxo4 mediated by hepatitis B virus X protein confers resistance to oxidative stress-induced cell death. Int J Mol Med (2011) 0.87
Inhibition of MKK7-JNK by the TOR signaling pathway regulator-like protein contributes to resistance of HCC cells to TRAIL-induced apoptosis. Gastroenterology (2012) 0.87
Ablation of peroxiredoxin II attenuates experimental colitis by increasing FoxO1-induced Foxp3+ regulatory T cells. J Immunol (2013) 0.87
Hepatitis B virus vector carries a foreign gene into liver cells in vitro. Virus Genes (2002) 0.87
Tumor suppressor protein p53 induces degradation of the oncogenic protein HBx. Cancer Lett (2009) 0.86
Interferon-gamma sensitizes hepatitis B virus-expressing hepatocarcinoma cells to 5-fluorouracil through inhibition of hepatitis B virus-mediated nuclear factor-kappaB activation. Cancer Sci (2007) 0.86
Hepatitis B virus X protein regulates hepatic glucose homeostasis via activation of inducible nitric oxide synthase. J Biol Chem (2011) 0.86
Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-dependent activation of phosphoinositide 3-kinase and p38 mitogen-activated protein kinase signal pathways is required for lipopolysaccharide-induced microglial phagocytosis. Biol Pharm Bull (2008) 0.85
Delayed occurrence of H-ras12V-induced hepatocellular carcinoma with long-term treatment with cinnamaldehydes. Eur J Pharmacol (2006) 0.85
Cooperative transformation of murine fibroblast NIH3T3 cells by hepatitis C virus core protein and hepatitis B virus X protein. Virus Res (2003) 0.85
Histone deacetylase 1 contributes to cell cycle and apoptosis. Biol Pharm Bull (2005) 0.85
Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors. Biochem Biophys Res Commun (2010) 0.85
Fidelity of hepatitis B virus polymerase. Eur J Biochem (2003) 0.84
Hepatitis B virus X protein induces TNF-alpha expression via down-regulation of selenoprotein P in human hepatoma cell line, HepG2. Biochim Biophys Acta (2003) 0.84
Prx I suppresses K-ras-driven lung tumorigenesis by opposing redox-sensitive ERK/cyclin D1 pathway. Antioxid Redox Signal (2013) 0.83
Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway. J Gen Virol (2002) 0.83
Hepatitis B virus X protein specially regulates the sialyl lewis a synthesis among glycosylation events for metastasis. Mol Cancer (2014) 0.83
The 113th and 117th charged amino acids in the 5th alpha-helix of the HBV core protein are necessary for pgRNA encapsidation. Virus Genes (2003) 0.82
Peroxiredoxin I contributes to TRAIL resistance through suppression of redox-sensitive caspase activation in human hepatoma cells. Carcinogenesis (2009) 0.82
The Effect of Metformin Treatment on CRBP-I Level and Cancer Development in the Liver of HBx Transgenic Mice. Korean J Physiol Pharmacol (2013) 0.82
Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage. Neurobiol Aging (2009) 0.82
Increased DNA polymerase fidelity of the Lamivudine resistant variants of human hepatitis B virus DNA polymerase. J Biochem Mol Biol (2004) 0.82
Interferon-gamma inhibits hepatitis B virus-induced NF-kappaB activation through nuclear localization of NF-kappaB-inducing kinase. Gastroenterology (2005) 0.81
Reactive oxygen species downregulate catalase expression via methylation of a CpG island in the Oct-1 promoter. FEBS Lett (2011) 0.81
Steatosis induced by the accumulation of apolipoprotein A-I and elevated ROS levels in H-ras12V transgenic mice contributes to hepatic lesions. Biochem Biophys Res Commun (2011) 0.81
HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. Virus Res (2008) 0.81
Suppression of tumor growth in H-ras12V liver cancer mice by delivery of programmed cell death protein 4 using galactosylated poly(ethylene glycol)-chitosan-graft-spermine. Biomaterials (2011) 0.81
iNOS promotes HBx-induced hepatocellular carcinoma via upregulation of JNK activation. Biochem Biophys Res Commun (2013) 0.80
Mefenamic acid-induced apoptosis in human liver cancer cell-lines through caspase-3 pathway. Life Sci (2004) 0.80
Identification of a mimotope for circulating anti-cytokeratin 8/18 antibody and its usage for the diagnosis of breast cancer. Int J Oncol (2012) 0.80
Reactive oxygen species mediated DNA damage is essential for abnormal erythropoiesis in peroxiredoxin II(-/-) mice. Biochem Biophys Res Commun (2012) 0.80
Hepatic steatosis in transgenic mice overexpressing human histone deacetylase 1. Biochem Biophys Res Commun (2005) 0.80
Dominant role of peroxiredoxin/JNK axis in stemness regulation during neurogenesis from embryonic stem cells. Stem Cells (2014) 0.80
Heat shock protein 90 facilitates formation of the HBV capsid via interacting with the HBV core protein dimers. Virology (2010) 0.80
The hepatitis B virus X protein up-regulates lymphotoxin alpha expression in hepatocytes. Biochim Biophys Acta (2004) 0.80
Orchiectomy reduces hepatotumorigenesis of H-ras12V transgenic mice via the MAPK pathway. Life Sci (2006) 0.80
Phosphorylation of hepatitis B virus core C-terminally truncated protein (Cp149) by PKC increases capsid assembly and stability. Biochem J (2008) 0.79