Published in FASEB J on December 19, 2003
Interdependence of hypoxic and innate immune responses. Nat Rev Immunol (2009) 3.29
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Hypoxia inducible factor (HIF) in rheumatology: low O2! See what HIF can do! Ann Rheum Dis (2005) 1.35
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The expression of hypoxia-inducible factor-1alpha in hepatitis B virus-related hepatocellular carcinoma: correlation with patients' prognosis and hepatitis B virus X protein. Dig Dis Sci (2008) 1.07
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Hepatitis B virus X protein and the estrogen receptor variant lacking exon 5 inhibit estrogen receptor signaling in hepatoma cells. Nucleic Acids Res (2006) 0.98
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Modulation of apoptotic signaling by the hepatitis B virus X protein. Viruses (2012) 0.93
Particular distribution and expression pattern of endoglin (CD105) in the liver of patients with hepatocellular carcinoma. BMC Cancer (2007) 0.92
Hepatitis B virus protein X-induced expression of the CXC chemokine IP-10 is mediated through activation of NF-kappaB and increases migration of leukocytes. J Biol Chem (2010) 0.92
Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib. J Transl Med (2011) 0.91
Hepatitis B virus promotes angiopoietin-2 expression in liver tissue: role of HBV x protein. Am J Pathol (2006) 0.89
Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoter. Cancer Gene Ther (2010) 0.87
BC-box protein domain-related mechanism for VHL protein degradation. Proc Natl Acad Sci U S A (2013) 0.86
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Angiogenesis: multiple masks in hepatocellular carcinoma and liver regeneration. Hepatol Int (2010) 0.84
Overexpression of cyclooxygenase-2 in noncancerous liver tissue increases the postoperative recurrence of hepatocellular carcinoma in patients with hepatitis B virus-related cirrhosis. Can J Gastroenterol (2010) 0.82
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Hypoxia inducible factor-1 alpha activation of the JCV promoter: role in the pathogenesis of progressive multifocal leukoencephalopathy. Acta Neuropathol (2009) 0.79
Potential mechanisms of hepatitis B virus induced liver injury. World J Gastroenterol (2014) 0.78
Molecular Pathogenesis of Hepatitis-B-virus-associated Hepatocellular Carcinoma. Gut Liver (2007) 0.77
Viral hepatitis markers in liver tissue in relation to serostatus in hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev (2013) 0.77
Differential functions of C- and N-terminal hepatitis B x protein in liver cells treated with doxorubicin in normoxic or hypoxic condition. PLoS One (2012) 0.76
Dissecting the pleiotropic actions of HBx mutants against hypoxia in hepatocellular carcinoma. Hepatobiliary Surg Nutr (2014) 0.75
A network-based maximum link approach towards MS identifies potentially important roles for undetected ARRB1/2 and ACTB in liver cancer progression. Int J Bioinform Res Appl (2012) 0.75
Risk of echocardiographic pulmonary hypertension in individuals with human immunodeficiency virus-hepatitis C virus coinfection. Ann Am Thorac Soc (2014) 0.75
A compendium of proteins that interact with HIF-1α. Exp Cell Res (2017) 0.75
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Analyses of pig genomes provide insight into porcine demography and evolution. Nature (2012) 5.58
Multi-platform next-generation sequencing of the domestic turkey (Meleagris gallopavo): genome assembly and analysis. PLoS Biol (2010) 5.39
Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling. Cell (2010) 3.82
Telomerase maintains telomere structure in normal human cells. Cell (2003) 3.29
Hypoxia-inducible factor (HIF-1)alpha: its protein stability and biological functions. Exp Mol Med (2004) 3.04
SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier. Nat Med (2003) 2.78
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II. Nature (2005) 2.29
Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice. Blood (2003) 2.05
Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity. J Biol Chem (2002) 1.75
Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene. Blood (2011) 1.73
Molecular functions and biological roles of hepatitis B virus x protein. Cancer Sci (2006) 1.72
Sumoylation increases HIF-1alpha stability and its transcriptional activity. Biochem Biophys Res Commun (2004) 1.70
Pharmacogenetic analysis of pediatric patients with acute lymphoblastic leukemia: a possible association between survival rate and ITPA polymorphism. PLoS One (2012) 1.60
Blood-neural barrier: intercellular communication at glio-vascular interface. J Biochem Mol Biol (2006) 1.59
Retracted Oligomeric interaction of hepatitis C virus NS5B is critical for catalytic activity of RNA-dependent RNA polymerase. J Biol Chem (2001) 1.51
Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull (2007) 1.51
Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology (2007) 1.45
Regression of low-grade gastric mucosa-associated lymphoid tissue lymphoma after eradication of Helicobacter pylori: possible association with p16 hypermethylation. J Gastroenterol (2002) 1.44
The transcriptional transactivation function of HBx protein is important for its augmentation role in hepatitis B virus replication. J Virol (2005) 1.43
CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs. J Clin Invest (2010) 1.41
Jab1 interacts directly with HIF-1alpha and regulates its stability. J Biol Chem (2001) 1.41
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells. Biochim Biophys Acta (2008) 1.41
Oxidative stress and antioxidants in hepatic pathogenesis. World J Gastroenterol (2010) 1.40
Hypoxia-induced angiogenesis during carcinogenesis. J Biochem Mol Biol (2003) 1.32
Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity. Biochem Biophys Res Commun (2003) 1.31
Syntenin is overexpressed and promotes cell migration in metastatic human breast and gastric cancer cell lines. Oncogene (2002) 1.31
VDUP1 is required for the development of natural killer cells. Immunity (2005) 1.31
Inactivating mutations of CASP10 gene in non-Hodgkin lymphomas. Blood (2002) 1.30
ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4. Nat Struct Mol Biol (2012) 1.30
Hepatitis B virus X protein enhances transcriptional activity of hypoxia-inducible factor-1alpha through activation of mitogen-activated protein kinase pathway. J Biol Chem (2003) 1.29
The multiplex bead array approach to identifying serum biomarkers associated with breast cancer. Breast Cancer Res (2009) 1.28
Structural basis for depletion of heat shock protein 90 client proteins by deguelin. J Natl Cancer Inst (2007) 1.27
Effect of interaction between hepatitis C virus NS5A and NS5B on hepatitis C virus RNA replication with the hepatitis C virus replicon. J Virol (2004) 1.26
Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1. Oncol Rep (2006) 1.26
Clinicopathologic features and prognostic implications of epidermal growth factor receptor (EGFR) gene copy number and protein expression in non-small cell lung cancer. Lung Cancer (2006) 1.25
Characterization of neural cell types expressing peroxiredoxins in mouse brain. Neurosci Lett (2005) 1.25
Local tumor invasiveness is more predictive of survival than International Prognostic Index in stage I(E)/II(E) extranodal NK/T-cell lymphoma, nasal type. Blood (2005) 1.24
ROS-induced ATF3 causes susceptibility to secondary infections during sepsis-associated immunosuppression. Nat Med (2011) 1.21
Anti-inflammatory effects of chlorogenic acid in lipopolysaccharide-stimulated RAW 264.7 cells. Inflamm Res (2013) 1.20
Interleukin-32 monoclonal antibodies for immunohistochemistry, Western blotting, and ELISA. J Immunol Methods (2008) 1.18
Visfatin promotes angiogenesis by activation of extracellular signal-regulated kinase 1/2. Biochem Biophys Res Commun (2007) 1.17
Capsaicin inhibits in vitro and in vivo angiogenesis. Cancer Res (2004) 1.16
Roles of peroxiredoxin II in the regulation of proinflammatory responses to LPS and protection against endotoxin-induced lethal shock. J Exp Med (2007) 1.16
Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4, and T-cell receptor gammadelta in plaque and guttate psoriasis. J Cutan Pathol (2007) 1.15
Dose-dependent biphasic activity of tRNA synthetase-associating factor, p43, in angiogenesis. J Biol Chem (2002) 1.14
Cytosolic peroxiredoxin attenuates the activation of Jnk and p38 but potentiates that of Erk in Hela cells stimulated with tumor necrosis factor-alpha. J Biol Chem (2003) 1.14
Hepatitis B virus infection and B-cell non-Hodgkin's lymphoma in a hepatitis B endemic area: a case-control study. Jpn J Cancer Res (2002) 1.14
Regulation of the HIF-1alpha stability by histone deacetylases. Oncol Rep (2007) 1.13
Hypoxia-induced angiogenesis in human hepatocellular carcinoma. J Mol Med (Berl) (2002) 1.13
MicroRNA-27a regulates lipid metabolism and inhibits hepatitis C virus replication in human hepatoma cells. J Virol (2013) 1.12
Blood-neural barrier: its diversity and coordinated cell-to-cell communication. BMB Rep (2008) 1.12
Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis. Int J Cancer (2002) 1.11
Melatonin suppresses tumor angiogenesis by inhibiting HIF-1alpha stabilization under hypoxia. J Pineal Res (2010) 1.11
Pro-MMP-2 activation by the PPARgamma agonist, ciglitazone, induces cell invasion through the generation of ROS and the activation of ERK. FEBS Lett (2007) 1.10
Angiopoietin-1 reduces vascular endothelial growth factor-induced brain endothelial permeability via upregulation of ZO-2. Int J Mol Med (2009) 1.09
Treatment outcome of angiocentric T-cell and NK/T-cell lymphoma, nasal type: radiotherapy versus chemoradiotherapy. Jpn J Clin Oncol (2005) 1.08
TNF-related activation-induced cytokine (TRANCE) induces angiogenesis through the activation of Src and phospholipase C (PLC) in human endothelial cells. J Biol Chem (2001) 1.08
Hypoxia-inducible factor-1 alpha inhibits self-renewal of mouse embryonic stem cells in Vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway. J Biol Chem (2007) 1.08
Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. Circ Res (2011) 1.08
Carbon monoxide promotes VEGF expression by increasing HIF-1alpha protein level via two distinct mechanisms, translational activation and stabilization of HIF-1alpha protein. J Biol Chem (2010) 1.07
Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt/β-catenin signaling. Cancer Lett (2010) 1.07
Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury. Glia (2012) 1.07
Metastatic tumor antigen 1 is closely associated with frequent postoperative recurrence and poor survival in patients with hepatocellular carcinoma. Hepatology (2008) 1.07
Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice. Stroke (2013) 1.07
Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity. J Biol Chem (2001) 1.07
HIF-1alpha: a valid therapeutic target for tumor therapy. Cancer Res Treat (2004) 1.06
Therapeutic outcome of extranodal NK/T-cell lymphoma initially treated with chemotherapy--result of chemotherapy in NK/T-cell lymphoma. Acta Oncol (2003) 1.06
Protective effect of clusterin from oxidative stress-induced apoptosis in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (2009) 1.06
Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation. Mol Endocrinol (2003) 1.06
Brain angiogenesis in developmental and pathological processes: regulation, molecular and cellular communication at the neurovascular interface. FEBS J (2009) 1.05
Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases. Nucleic Acids Res (2009) 1.05
Concerted action of sulfiredoxin and peroxiredoxin I protects against alcohol-induced oxidative injury in mouse liver. Hepatology (2011) 1.05
Peroxiredoxin II is an essential antioxidant enzyme that prevents the oxidative inactivation of VEGF receptor-2 in vascular endothelial cells. Mol Cell (2011) 1.05
Non-structural 5A protein of hepatitis C virus induces a range of liver pathology in transgenic mice. J Pathol (2009) 1.04
USP8 is a novel target for overcoming gefitinib resistance in lung cancer. Clin Cancer Res (2013) 1.04
Recruitment of pericytes and astrocytes is closely related to the formation of tight junction in developing retinal vessels. J Neurosci Res (2009) 1.04
Coordinated interaction of the vascular and nervous systems: from molecule- to cell-based approaches. Biochem Biophys Res Commun (2003) 1.04
Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents. Bioorg Med Chem Lett (2004) 1.04
Direct activation of telomerase by EGF through Ets-mediated transactivation of TERT via MAP kinase signaling pathway. Oncogene (2002) 1.04
Profiling of transcripts and proteins modulated by K-ras oncogene in the lung tissues of K-ras transgenic mice by omics approaches. Int J Oncol (2009) 1.04
Resveratrol, a red wine polyphenol, suppresses pancreatic cancer by inhibiting leukotriene A₄hydrolase. Cancer Res (2010) 1.04
Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury. J Clin Invest (2013) 1.02
Subcellular localization of RPB5-mediating protein and its putative functional partner. Mol Cell Biol (2004) 1.02
Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha. Int J Cancer (2008) 1.02
Neuronal genes for subcutaneous fat thickness in human and pig are identified by local genomic sequencing and combined SNP association study. PLoS One (2011) 1.02
Intravenously administered gold nanoparticles pass through the blood-retinal barrier depending on the particle size, and induce no retinal toxicity. Nanotechnology (2009) 1.01
Metastasis-associated protein 1 enhances angiogenesis by stabilization of HIF-1alpha. Oncol Rep (2006) 1.01
Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP). Cell Res (2003) 1.01
Characterization of ARD1 variants in mammalian cells. Biochem Biophys Res Commun (2005) 1.01