Published in J Cell Biol on October 25, 2010
Spindle position in symmetric cell divisions during epiboly is controlled by opposing and dynamic apicobasal forces. Dev Cell (2012) 1.59
The centrosome is an actin-organizing centre. Nat Cell Biol (2015) 1.54
AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain. Mol Cell Biol (2012) 1.29
Cellular control of cortical actin nucleation. Curr Biol (2014) 1.16
And the dead shall rise: actin and myosin return to the spindle. Dev Cell (2011) 1.11
Ehrlichia chaffeensis TRP120 interacts with a diverse array of eukaryotic proteins involved in transcription, signaling, and cytoskeleton organization. Infect Immun (2011) 0.97
Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. Proc Natl Acad Sci U S A (2013) 0.96
Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds. Dev Cell (2015) 0.93
Regulation of mitotic spindle orientation: an integrated view. EMBO Rep (2016) 0.84
Cell-cycle regulation of formin-mediated actin cable assembly. Proc Natl Acad Sci U S A (2013) 0.83
Adducin-1 is essential for mitotic spindle assembly through its interaction with myosin-X. J Cell Biol (2013) 0.82
Force and the spindle: mechanical cues in mitotic spindle orientation. Semin Cell Dev Biol (2014) 0.81
Evolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human. PLoS One (2012) 0.81
Oocyte Maturation and Development. F1000Res (2016) 0.79
Coupling changes in cell shape to chromosome segregation. Nat Rev Mol Cell Biol (2016) 0.79
Characterization of ring-like F-actin structure as a mechanical partner for spindle positioning in mitosis. PLoS One (2014) 0.78
Cell shape impacts on the positioning of the mitotic spindle with respect to the substratum. Mol Biol Cell (2015) 0.76
Might makes right: Using force to align the mitotic spindle. Nat Cell Biol (2011) 0.76
Fimbrin phosphorylation by metaphase Cdk1 regulates actin cable dynamics in budding yeast. Nat Commun (2016) 0.76
A Subpopulation of the K562 Cells Are Killed by Curcumin Treatment after G2/M Arrest and Mitotic Catastrophe. PLoS One (2016) 0.75
Actomyosin-dependent dynamic spatial patterns of cytoskeletal components drive mesoscale podosome organization. Nat Commun (2016) 0.75
Foci of cyclin A2 interact with actin and RhoA in mitosis. Sci Rep (2016) 0.75
Screening of differentially expressed proteins in psoriasis vulgaris by two-dimensional gel electrophoresis and mass spectrometry. Exp Ther Med (2017) 0.75
Rho GTPases in cell biology. Nature (2002) 22.81
Regulation of actin filament assembly by Arp2/3 complex and formins. Annu Rev Biophys Biomol Struct (2007) 6.87
Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci U S A (2006) 5.16
The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol (2005) 5.00
Cortical flow in animal cells. Science (1988) 4.66
Versatile fluorescent probes for actin filaments based on the actin-binding domain of utrophin. Cell Motil Cytoskeleton (2007) 4.61
Myosin II-dependent cortical movement is required for centrosome separation and positioning during mitotic spindle assembly. Cell (2004) 3.18
Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse. Immunity (2007) 3.14
Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis. Curr Biol (2008) 2.92
Actin dynamics in living mammalian cells. J Cell Sci (1998) 2.86
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J (2007) 2.73
The complex containing actin-related proteins Arp2 and Arp3 is required for the motility and integrity of yeast actin patches. Curr Biol (1997) 2.71
Regulation of cytokinesis by Rho GTPase flux. Nat Cell Biol (2008) 2.50
A contractile nuclear actin network drives chromosome congression in oocytes. Nature (2005) 2.45
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes. Mol Biol Cell (2006) 2.36
RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J Cell Biol (2003) 2.34
Actin nucleation and elongation factors: mechanisms and interplay. Curr Opin Cell Biol (2009) 2.27
Moesin and its activating kinase Slik are required for cortical stability and microtubule organization in mitotic cells. J Cell Biol (2008) 2.02
Myosin-10 and actin filaments are essential for mitotic spindle function. J Cell Biol (2008) 1.99
Spindle positioning in mouse oocytes relies on a dynamic meshwork of actin filaments. Curr Biol (2008) 1.97
Annexin A2-dependent polymerization of actin mediates endosome biogenesis. Dev Cell (2009) 1.67
Actin-driven chromosomal motility leads to symmetry breaking in mammalian meiotic oocytes. Nat Cell Biol (2008) 1.65
Actin based motility on retraction fibers in mitotic PtK2 cells. Cell Motil Cytoskeleton (1992) 1.51
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia. J Exp Med (2007) 1.49
Caenorhabditis elegans WASP and Ena/VASP proteins play compensatory roles in morphogenesis and neuronal cell migration. Genetics (2004) 1.41
Analysis of the mechanisms of Salmonella-induced actin assembly during invasion of host cells and intracellular replication. Cell Microbiol (2004) 1.40
WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2. Nat Cell Biol (2008) 1.38
Overexpression of normal and mutant Arp1alpha (centractin) differentially affects microtubule organization during mitosis and interphase. J Cell Sci (1999) 1.21
AIP1/WDR1 supports mitotic cell rounding. Biochem Biophys Res Commun (2005) 1.20
Dual role for microtubules in regulating cortical contractility during cytokinesis. J Cell Sci (2008) 1.15
Changes in the balance between caldesmon regulated by p21-activated kinases and the Arp2/3 complex govern podosome formation. J Biol Chem (2007) 1.01
Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis. J Cell Sci (2009) 0.96
Inhibition of cytokinesis by wiskostatin does not rely on N-WASP/Arp2/3 complex pathway. BMC Cell Biol (2008) 0.86
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat Immunol (2004) 5.71
Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells. Mol Cell Biol (2002) 4.50
Ripples from neighbouring transcription. Nat Cell Biol (2008) 3.87
Activity of Rho-family GTPases during cell division as visualized with FRET-based probes. J Cell Biol (2003) 3.85
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene (2003) 3.53
Cathepsin K-dependent toll-like receptor 9 signaling revealed in experimental arthritis. Science (2008) 3.38
Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat Cell Biol (2002) 3.35
Identification of a consensus motif for Plk (Polo-like kinase) phosphorylation reveals Myt1 as a Plk1 substrate. J Biol Chem (2003) 3.30
JNK functions in the non-canonical Wnt pathway to regulate convergent extension movements in vertebrates. EMBO Rep (2001) 3.08
Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo. Nat Med (2004) 2.94
Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction. J Exp Med (2005) 2.90
The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev (2005) 2.81
Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med (2012) 2.80
Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes. J Biol Chem (2006) 2.73
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J (2007) 2.73
Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr Biol (2006) 2.59
Localized RhoA activation as a requirement for the induction of membrane ruffling. Mol Biol Cell (2005) 2.58
CD4 T follicular helper cell dynamics during SIV infection. J Clin Invest (2012) 2.55
PtdIns(3,4,5)P3 regulates spindle orientation in adherent cells. Dev Cell (2007) 2.45
The duration, magnitude and compartmentalization of ERK MAP kinase activity: mechanisms for providing signaling specificity. J Cell Sci (2005) 2.40
Molecular recognitions in the MAP kinase cascades. Cell Signal (2003) 2.36
Development of an optimized backbone of FRET biosensors for kinases and GTPases. Mol Biol Cell (2011) 2.28
Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2. Genes Dev (2004) 2.22
MAPK signalling: ERK5 versus ERK1/2. EMBO Rep (2006) 2.19
Plk1 promotes nuclear translocation of human Cdc25C during prophase. EMBO Rep (2002) 2.15
Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans. Nature (2008) 2.14
Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells. Mol Cell Biol (2002) 2.13
The Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-Src. Mol Cell Biol (2006) 2.11
Sef is a spatial regulator for Ras/MAP kinase signaling. Dev Cell (2004) 2.04
Roles played by a subset of integrin signaling molecules in cadherin-based cell-cell adhesion. J Cell Biol (2004) 2.02
ERK activation propagates in epithelial cell sheets and regulates their migration during wound healing. Curr Biol (2004) 2.00
E-selectin receptors on human leukocytes. Blood (2008) 1.99
Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med (2006) 1.93
Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol (2007) 1.92
HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration. Nature (2013) 1.84
A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling. EMBO J (2012) 1.81
XGAP, an ArfGAP, is required for polarized localization of PAR proteins and cell polarity in Xenopus gastrulation. Dev Cell (2006) 1.79
The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO J (2004) 1.76
Cell type-specific regulation of RhoA activity during cytokinesis. J Biol Chem (2004) 1.76
IkappaBzeta regulates T(H)17 development by cooperating with ROR nuclear receptors. Nature (2010) 1.76
Lateral propagation of EGF signaling after local stimulation is dependent on receptor density. Dev Cell (2002) 1.74
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. Mol Biol Cell (2003) 1.72
SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility. Mol Cell (2011) 1.70
Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport. Nat Struct Mol Biol (2009) 1.64
Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation. Mol Cell (2013) 1.62
Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase. EMBO Rep (2005) 1.62
A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions. Cell Rep (2012) 1.60
A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis. J Biol Chem (2004) 1.56
Processive phosphorylation of ERK MAP kinase in mammalian cells. Proc Natl Acad Sci U S A (2011) 1.55
Regulation of MAP kinases by MAP kinase phosphatases. Biochim Biophys Acta (2006) 1.54
Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors. Nat Protoc (2009) 1.53
Local phosphatidylinositol 3,4,5-trisphosphate accumulation recruits Vav2 and Vav3 to activate Rac1/Cdc42 and initiate neurite outgrowth in nerve growth factor-stimulated PC12 cells. Mol Biol Cell (2005) 1.48
CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37. Mol Cell Biol (2004) 1.44
Noninvasive method for assessing the human circadian clock using hair follicle cells. Proc Natl Acad Sci U S A (2010) 1.43
Docking interactions in the mitogen-activated protein kinase cascades. Pharmacol Ther (2002) 1.43
Site mapping and characterization of O-glycan structures on alpha-dystroglycan isolated from rabbit skeletal muscle. J Biol Chem (2010) 1.43
Temperature compensation and temperature resetting of circadian rhythms in mammalian cultured fibroblasts. Genes Cells (2003) 1.42
Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells. J Biol Chem (2003) 1.41
ERK MAP kinase in G cell cycle progression and cancer. Cancer Sci (2006) 1.41
Mechanism of the spatio-temporal regulation of Ras and Rap1. EMBO J (2003) 1.40
FGF induces oscillations of Hes1 expression and Ras/ERK activation. Curr Biol (2008) 1.40
Imaging of Rab5 activity identifies essential regulators for phagosome maturation. Nature (2008) 1.39
Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway. J Cell Biol (2009) 1.36
Percutaneous CT-guided puncture and steroid injection for the treatment of lumbar discal cyst: a case report. Spine (Phila Pa 1976) (2003) 1.35
Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro. PLoS One (2013) 1.34
Regulatory mechanisms and function of ERK MAP kinases. J Biochem (2004) 1.34
Polo-like kinase 1 facilitates chromosome alignment during prometaphase through BubR1. J Biol Chem (2007) 1.33
Glycomic analyses of mouse models of congenital muscular dystrophy. J Biol Chem (2011) 1.32
A clathrin-dependent pathway leads to KRas signaling on late endosomes en route to lysosomes. J Cell Biol (2009) 1.30
Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis. J Cell Biol (2010) 1.30
Signaling pathway via TNF-alpha/NF-kappaB in intestinal epithelial cells may be directly involved in colitis-associated carcinogenesis. Am J Physiol Gastrointest Liver Physiol (2009) 1.27
Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin-induced activation of Cdc42 and formation of adherens junctions. J Biol Chem (2004) 1.26
An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells. J Cell Biol (2007) 1.25
Self-assembly of flexible supramolecular metallacyclic ensembles: structures and adsorption properties of their nanoporous crystalline frameworks. J Am Chem Soc (2004) 1.25
Dual role of Cdc42 in spindle orientation control of adherent cells. Mol Cell Biol (2009) 1.24
Rap1-PDZ-GEF1 interacts with a neurotrophin receptor at late endosomes, leading to sustained activation of Rap1 and ERK and neurite outgrowth. J Cell Biol (2007) 1.23
Novel nuclear import of Vpr promoted by importin alpha is crucial for human immunodeficiency virus type 1 replication in macrophages. J Virol (2007) 1.23
Involvement of the protein kinase CK2 in the regulation of mammalian circadian rhythms. Sci Signal (2009) 1.21
Monitoring spatio-temporal regulation of Ras and Rho GTPase with GFP-based FRET probes. Methods (2005) 1.21
ABL1 regulates spindle orientation in adherent cells and mammalian skin. Nat Commun (2012) 1.20