Published in J Biol Chem on October 25, 2010
Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport. Proc Natl Acad Sci U S A (2011) 1.23
The kinetics of mechanically coupled myosins exhibit group size-dependent regimes. Biophys J (2013) 0.89
More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin Va. J Biol Chem (2013) 0.88
Vascular disease-causing mutation R258C in ACTA2 disrupts actin dynamics and interaction with myosin. Proc Natl Acad Sci U S A (2015) 0.87
Myosin VI has a one track mind versus myosin Va when moving on actin bundles or at an intersection. Traffic (2012) 0.85
Quantum dots find their stride in single molecule tracking. Curr Opin Chem Biol (2011) 0.83
A branched kinetic scheme describes the mechanochemical coupling of Myosin Va processivity in response to substrate. Biophys J (2012) 0.77
Phosphorylation of myosin regulatory light chain has minimal effect on kinetics and distribution of orientations of cross bridges of rabbit skeletal muscle. Am J Physiol Regul Integr Comp Physiol (2013) 0.76
Mesoscopic analysis of motion and conformation of cross-bridges. Biophys Rev (2012) 0.75
Myosin Vc Is Specialized for Transport on a Secretory Superhighway. Curr Biol (2016) 0.75
Myosin-V is a processive actin-based motor. Nature (1999) 7.13
Assembly dynamics of microtubules at molecular resolution. Nature (2006) 5.52
The gated gait of the processive molecular motor, myosin V. Nat Cell Biol (2002) 5.34
Myosin-V stepping kinetics: a molecular model for processivity. Proc Natl Acad Sci U S A (2000) 5.03
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Load-dependent kinetics of myosin-V can explain its high processivity. Nat Cell Biol (2005) 3.69
Myosin V processivity: multiple kinetic pathways for head-to-head coordination. Proc Natl Acad Sci U S A (2004) 2.49
Myosin V: regulation by calcium, calmodulin, and the tail domain. J Cell Biol (2004) 2.40
Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys J (2005) 2.31
Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trap. Biophys J (1997) 2.28
Actin filament mechanics in the laser trap. J Muscle Res Cell Motil (1997) 1.97
Myosin V is a left-handed spiral motor on the right-handed actin helix. Nat Struct Biol (2002) 1.95
Force-dependent stepping kinetics of myosin-V. Biophys J (2005) 1.88
Myosin V from head to tail. Cell Mol Life Sci (2008) 1.76
Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc Natl Acad Sci U S A (2008) 1.65
Elastic lever-arm model for myosin V. Biophys J (2005) 1.62
Direct observation of the myosin-Va power stroke and its reversal. Nat Struct Mol Biol (2010) 1.28
A mutant heterodimeric myosin with one inactive head generates maximal displacement. J Cell Biol (2003) 1.26
Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem (2008) 1.24
A nonprocessive class V myosin drives cargo processively when a kinesin- related protein is a passenger. Curr Biol (2009) 1.21
Regulation of myosin V processivity by calcium at the single molecule level. J Biol Chem (2006) 1.10
Phosphorylation of a single head of smooth muscle myosin activates the whole molecule. Biochemistry (2006) 0.97
Robust processivity of myosin V under off-axis loads. Nat Chem Biol (2010) 0.91
The lever arm effects a mechanical asymmetry of the myosin-V-actin bond. Biophys J (2010) 0.81
Myosin V processivity: multiple kinetic pathways for head-to-head coordination. Proc Natl Acad Sci U S A (2004) 2.49
Myosin V: regulation by calcium, calmodulin, and the tail domain. J Cell Biol (2004) 2.40
Cargo transport: molecular motors navigate a complex cytoskeleton. Curr Opin Cell Biol (2008) 2.39
Three-dimensional structure of the myosin V inhibited state by cryoelectron tomography. Nature (2006) 2.39
Differential labeling of myosin V heads with quantum dots allows direct visualization of hand-over-hand processivity. Biophys J (2005) 2.31
Myosin Va maneuvers through actin intersections and diffuses along microtubules. Proc Natl Acad Sci U S A (2007) 2.14
The myosin power stroke. Cell Motil Cytoskeleton (2002) 1.88
Tropomyosin is essential for processive movement of a class V myosin from budding yeast. Curr Biol (2012) 1.84
The structural basis of myosin V processive movement as revealed by electron cryomicroscopy. Mol Cell (2005) 1.82
Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor. Circ Res (2012) 1.69
Myosin V and Kinesin act as tethers to enhance each others' processivity. Proc Natl Acad Sci U S A (2008) 1.65
Crystal structure of apo-calmodulin bound to the first two IQ motifs of myosin V reveals essential recognition features. Proc Natl Acad Sci U S A (2006) 1.63
Crystal structures of expressed non-polymerizable monomeric actin in the ADP and ATP states. J Biol Chem (2006) 1.62
The biochemical kinetics underlying actin movement generated by one and many skeletal muscle myosin molecules. Biophys J (2002) 1.59
Human actin mutations associated with hypertrophic and dilated cardiomyopathies demonstrate distinct thin filament regulatory properties in vitro. J Mol Cell Cardiol (2009) 1.57
Analysis of myosin heavy chain functionality in the heart. J Biol Chem (2003) 1.57
Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single- molecule imaging of quantum-dot-labeled proteins. Mol Cell (2010) 1.40
Unique single molecule binding of cardiac myosin binding protein-C to actin and phosphorylation-dependent inhibition of actomyosin motility requires 17 amino acids of the motif domain. J Mol Cell Cardiol (2011) 1.40
Random walk of processive, quantum dot-labeled myosin Va molecules within the actin cortex of COS-7 cells. Biophys J (2009) 1.37
Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA. Nucleic Acids Res (2011) 1.32
A mutant heterodimeric myosin with one inactive head generates maximal displacement. J Cell Biol (2003) 1.26
Engineering the processive run length of Myosin V. J Biol Chem (2007) 1.25
Load and Pi control flux through the branched kinetic cycle of myosin V. J Biol Chem (2008) 1.24
Myosin Va and myosin VI coordinate their steps while engaged in an in vitro tug of war during cargo transport. Proc Natl Acad Sci U S A (2011) 1.23
Alpha-cardiac actin mutations produce atrial septal defects. Hum Mol Genet (2007) 1.21
A nonprocessive class V myosin drives cargo processively when a kinesin- related protein is a passenger. Curr Biol (2009) 1.21
Molecular mechanics of mouse cardiac myosin isoforms. Am J Physiol Heart Circ Physiol (2002) 1.17
Does the myosin V neck region act as a lever? J Muscle Res Cell Motil (2004) 1.16
Single-myosin crossbridge interactions with actin filaments regulated by troponin-tropomyosin. Proc Natl Acad Sci U S A (2005) 1.16
Mutation of a conserved glycine in the SH1-SH2 helix affects the load-dependent kinetics of myosin. Biophys J (2006) 1.15
Distribution and structure-function relationship of myosin heavy chain isoforms in the adult mouse heart. J Biol Chem (2007) 1.15
A point mutation in the regulatory light chain reduces the step size of skeletal muscle myosin. Proc Natl Acad Sci U S A (2004) 1.15
Cardiac myosin binding protein-C modulates actomyosin binding and kinetics in the in vitro motility assay. J Mol Cell Cardiol (2008) 1.15
Mechanical coupling between myosin molecules causes differences between ensemble and single-molecule measurements. Biophys J (2012) 1.15
Slip sliding away: load-dependence of velocity generated by skeletal muscle myosin molecules in the laser trap. Biophys J (2005) 1.14
She3p binds to the rod of yeast myosin V and prevents it from dimerizing, forming a single-headed motor complex. J Biol Chem (2008) 1.13
Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism. Proc Natl Acad Sci U S A (2014) 1.10
Myosin isoforms show unique conformations in the actin-bound state. Proc Natl Acad Sci U S A (2003) 1.10
Regulation of myosin V processivity by calcium at the single molecule level. J Biol Chem (2006) 1.10
Common structural motifs for the regulation of divergent class II myosins. J Biol Chem (2010) 1.08
A small-molecule inhibitor of T. gondii motility induces the posttranslational modification of myosin light chain-1 and inhibits myosin motor activity. PLoS Pathog (2010) 1.08
Collective dynamics of elastically coupled myosin V motors. J Biol Chem (2012) 1.06
In vivo optical trapping indicates kinesin's stall force is reduced by dynein during intracellular transport. Proc Natl Acad Sci U S A (2013) 1.05
Expression of a nonpolymerizable actin mutant in Sf9 cells. Biochemistry (2004) 1.05
A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin. J Biol Chem (2013) 1.04
The converter domain modulates kinetic properties of Drosophila myosin. Am J Physiol Cell Physiol (2002) 1.04
Molecular and phenotypic effects of heterozygous, homozygous, and compound heterozygote myosin heavy-chain mutations. Am J Physiol Heart Circ Physiol (2004) 1.03
Two single-headed myosin V motors bound to a tetrameric adapter protein form a processive complex. J Cell Biol (2011) 1.03
Functional consequences of a mutation in an expressed human alpha-cardiac actin at a site implicated in familial hypertrophic cardiomyopathy. J Biol Chem (2006) 1.02
Processivity of chimeric class V myosins. J Biol Chem (2005) 1.01
Single-molecule reconstitution of mRNA transport by a class V myosin. Nat Struct Mol Biol (2013) 1.01
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc Natl Acad Sci U S A (2010) 1.00
Phosphorylation of a single head of smooth muscle myosin activates the whole molecule. Biochemistry (2006) 0.97
The extent of cardiac myosin binding protein-C phosphorylation modulates actomyosin function in a graded manner. J Muscle Res Cell Motil (2012) 0.97
Smooth muscle heavy meromyosin phosphorylated on one of its two heads supports force and motion. J Biol Chem (2009) 0.97
Addition of lysines to the 50/20 kDa junction of myosin strengthens weak binding to actin without affecting the maximum ATPase activity. Biochemistry (2003) 0.97
Fission yeast tropomyosin specifies directed transport of myosin-V along actin cables. Mol Biol Cell (2013) 0.96
The unique properties of tonic smooth muscle emerge from intrinsic as well as intermolecular behaviors of Myosin molecules. J Biol Chem (2003) 0.96
The carboxyl-terminal isoforms of smooth muscle myosin heavy chain determine thick filament assembly properties. J Cell Biol (2002) 0.96
Crystal structures of monomeric actin bound to cytochalasin D. J Mol Biol (2008) 0.95
Diffusive movement of processive kinesin-1 on microtubules. Traffic (2009) 0.95
The R403Q myosin mutation implicated in familial hypertrophic cardiomyopathy causes disorder at the actomyosin interface. PLoS One (2007) 0.90
Phosphorylated smooth muscle heavy meromyosin shows an open conformation linked to activation. J Mol Biol (2011) 0.89
Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences. J Biol Chem (2013) 0.89
Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif. Biophys J (2013) 0.88
More than just a cargo adapter, melanophilin prolongs and slows processive runs of myosin Va. J Biol Chem (2013) 0.88
Essential features of the class V myosin from budding yeast for ASH1 mRNA transport. Mol Biol Cell (2009) 0.86
Motor domain phosphorylation modulates kinesin-1 transport. J Biol Chem (2013) 0.85
Delineating cooperative responses of processive motors in living cells. Proc Natl Acad Sci U S A (2014) 0.85
Myosin VI has a one track mind versus myosin Va when moving on actin bundles or at an intersection. Traffic (2012) 0.85
Full-length myosin Va exhibits altered gating during processive movement on actin. Proc Natl Acad Sci U S A (2012) 0.84
The two heads of smooth muscle myosin are enzymatically independent but mechanically interactive. J Biol Chem (2003) 0.82
Functional effects of nemaline myopathy mutations on human skeletal alpha-actin. J Biol Chem (2008) 0.81
Biopanning Phage-Display Libraries on Small Tissue Sections Captured by Laser Capture Microdissection. J Biotech Res (2009) 0.80
No strain, no gain. Nat Cell Biol (2005) 0.80
Molecular architecture of the Spire-actin nucleus and its implication for actin filament assembly. Proc Natl Acad Sci U S A (2011) 0.80