Published in J Cell Mol Med on October 01, 2011
Tumor suppressor functions of FBW7 in cancer development and progression. FEBS Lett (2012) 1.64
Shielding the messenger (RNA): microRNA-based anticancer therapies. Pharmacol Ther (2011) 1.12
Friend or foe: the role of microRNA in chemotherapy resistance. Acta Pharmacol Sin (2013) 1.11
Aberrant regulation of FBW7 in cancer. Oncotarget (2014) 1.08
The two faces of FBW7 in cancer drug resistance. Bioessays (2011) 1.08
A set of miRNAs that involve in the pathways of drug resistance and leukemic stem-cell differentiation is associated with the risk of relapse and glucocorticoid response in childhood ALL. Hum Mol Genet (2011) 1.07
MiR-27a functions as a tumor suppressor in acute leukemia by regulating 14-3-3θ. PLoS One (2012) 1.04
miRNA profiles as a predictor of chemoresponsiveness in Wilms' tumor blastema. PLoS One (2013) 1.02
Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression. Cell Death Dis (2013) 1.01
MicroRNA: important player in the pathobiology of multiple myeloma. Biomed Res Int (2014) 0.89
MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy. Drug Metab Dispos (2015) 0.89
Bortezomib action in multiple myeloma: microRNA-mediated synergy (and miR-27a/CDK5 driven sensitivity)? Blood Cancer J (2012) 0.88
Molecular and genetic alterations associated with therapy resistance and relapse of acute myeloid leukemia. J Hematol Oncol (2017) 0.85
A serum microRNA signature associated with complete remission and progression after autologous stem-cell transplantation in patients with multiple myeloma. Oncotarget (2015) 0.85
MicroRNAs and their relevance to ABC transporters. Br J Clin Pharmacol (2014) 0.83
Altered expression of miR-24, miR-126 and miR-365 does not affect viability of childhood TCF3-rearranged leukemia cells. Leukemia (2013) 0.81
MicroRNAs: key players of taxane resistance and their therapeutic potential in human cancers. J Cell Mol Med (2013) 0.81
MicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid Malignancies. ISRN Hematol (2013) 0.80
MiR-424 and miR-27a increase TRAIL sensitivity of acute myeloid leukemia by targeting PLAG1. Oncotarget (2016) 0.78
Association between pre-miR-27a functional polymorphism and risk of colorectal cancer in north Chinese Han population. Onco Targets Ther (2015) 0.78
MicroRNAs in B-cells: from normal differentiation to treatment of malignancies. Oncotarget (2015) 0.77
Role of micro-RNAs in drug resistance of multiple myeloma. Oncotarget (2016) 0.77
The Profile of Serum microRNAs Predicts Prognosis for Resected Gastric Cancer Patients Receiving Platinum-Based Chemotherapy. Dig Dis Sci (2017) 0.77
Membrane microparticles: shedding new light into cancer cell communication. J Cancer Res Clin Oncol (2015) 0.76
Role of miR-27a, miR-181a and miR-20b in gastric cancer hypoxia-induced chemoresistance. Cancer Biol Ther (2016) 0.76
Microparticles induce multifactorial resistance through oncogenic pathways independently of cancer cell type. Cancer Sci (2014) 0.76
Effect of Propofol on microRNA Expression Profile in Adipocyte-Derived Adult Stem Cells. Chonnam Med J (2014) 0.76
Mechanisms of doxorubicin resistance in hepatocellular carcinoma. Hepat Oncol (2016) 0.75
Therapeutic Resistance in Acute Myeloid Leukemia: The Role of Non-Coding RNAs. Int J Mol Sci (2016) 0.75
Alpha-2, 3-sialyltransferases regulate the multidrug resistance of chronic myeloid leukemia through miR-4701-5p targeting ST3GAL1. Lab Invest (2016) 0.75
Regulation of multidrug resistance by microRNAs in anti-cancer therapy. Acta Pharm Sin B (2016) 0.75
MicroRNAs as prognostic biomarker and relapse indicator in leukemia. Clin Transl Oncol (2017) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 198.59
Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci U S A (1998) 192.97
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell (2005) 96.87
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature (2005) 31.60
Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol (2008) 8.55
MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res (2008) 7.45
Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res (2007) 6.57
miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer (2008) 4.09
The oncogenic microRNA-27a targets genes that regulate specificity protein transcription factors and the G2-M checkpoint in MDA-MB-231 breast cancer cells. Cancer Res (2007) 3.40
The role of ABC transporters in clinical practice. Oncologist (2003) 3.21
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol Cancer Ther (2008) 2.85
Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm Genome (2006) 2.64
Role of MicroRNA miR-27a and miR-451 in the regulation of MDR1/P-glycoprotein expression in human cancer cells. Biochem Pharmacol (2008) 2.56
Taxanes, microtubules and chemoresistant breast cancer. Biochim Biophys Acta (2007) 2.45
miR-34a as a prognostic marker of relapse in surgically resected non-small-cell lung cancer. Carcinogenesis (2009) 2.41
Evolution of resistance during clonal expansion. Genetics (2006) 2.36
Expression of the multidrug resistance-associated P-glycoprotein (P-170) in 59 cases of de novo acute lymphoblastic leukemia: prognostic implications. Blood (1993) 1.99
Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation. Eur J Cancer (2009) 1.97
Epigenetics as a mechanism driving polygenic clinical drug resistance. Br J Cancer (2006) 1.77
Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence. Int J Cancer (2010) 1.76
Involvement of miR-326 in chemotherapy resistance of breast cancer through modulating expression of multidrug resistance-associated protein 1. Biochem Pharmacol (2009) 1.75
The promise of TRAIL--potential and risks of a novel anticancer therapy. J Mol Med (Berl) (2007) 1.73
MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia. PLoS One (2009) 1.62
Oncogenic microRNA-27a is a target for anticancer agent methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate in colon cancer cells. Int J Cancer (2009) 1.60
miRNA expression profiles in chronic lymphocytic and acute lymphocytic leukemia. Braz J Med Biol Res (2007) 1.59
Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma. Blood (2009) 1.45
In vitro cellular drug resistance and prognosis in newly diagnosed childhood acute lymphoblastic leukemia. Blood (1997) 1.28
Multiple paths to a drug resistance phenotype: mutations, translocations, deletions and amplification of coding genes or promoter regions, epigenetic changes and microRNAs. Drug Resist Updat (2007) 1.22
Multiple genetic and epigenetic interacting mechanisms contribute to clonally selection of drug-resistant tumors: current views and new therapeutic prospective. J Cell Physiol (2006) 1.20
Computational identification of microRNAs and their targets. Birth Defects Res C Embryo Today (2006) 1.18
miR-138 might reverse multidrug resistance of leukemia cells. Leuk Res (2009) 1.18
Clinical studies with modulators of multidrug resistance. Hematol Oncol Clin North Am (1995) 1.06
Role of multidrug resistance and its pharmacological modulation in acute myeloid leukemia. Leukemia (1996) 1.03
Correlation of P-glycoprotein expression and function in childhood acute leukemia: a children's cancer group study. Blood (1996) 0.87
Troglitazone reverses the multiple drug resistance phenotype in cancer cells. Drug Des Devel Ther (2009) 0.87
Sequential gene expression of P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines. Anticancer Drugs (2001) 0.81
Upregulation of multi drug resistance genes in doxorubicin resistant human acute myelogeneous leukemia cells and reversal of the resistance. Hematology (2007) 0.79
Multi-drug resistance genes in the management of neoplastic disease. J Vet Intern Med (1991) 0.78
Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1. Science (2010) 14.91
Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature (2007) 11.73
The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science (2007) 11.15
Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01. Science (2010) 10.69
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02
Accelerated vaccination for Ebola virus haemorrhagic fever in non-human primates. Nature (2003) 6.35
Preserved CD4+ central memory T cells and survival in vaccinated SIV-challenged monkeys. Science (2006) 6.06
Induction of broadly neutralizing H1N1 influenza antibodies by vaccination. Science (2010) 5.13
Trends in access to health services and financial protection in China between 2003 and 2011: a cross-sectional study. Lancet (2012) 4.98
The chemistry of two-dimensional layered transition metal dichalcogenide nanosheets. Nat Chem (2013) 4.57
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res (2013) 4.33
Structural basis of immune evasion at the site of CD4 attachment on HIV-1 gp120. Science (2009) 4.20
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication. Science (2007) 4.12
starBase: a database for exploring microRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data. Nucleic Acids Res (2010) 3.99
Acetylation of histone H3 lysine 56 regulates replication-coupled nucleosome assembly. Cell (2008) 3.96
Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res (2009) 3.86
TGM6 identified as a novel causative gene of spinocerebellar ataxias using exome sequencing. Brain (2010) 3.66
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets. J Exp Med (2008) 3.48
Single-layer MoS2 phototransistors. ACS Nano (2011) 3.43
LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer. Cell (2009) 3.34
Plant snoRNA database. Nucleic Acids Res (2003) 3.15
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery. Nucleic Acids Res (2011) 3.05
Immunization by avian H5 influenza hemagglutinin mutants with altered receptor binding specificity. Science (2007) 2.95
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 2.90
Fasting plasma glucose at 24-28 weeks to screen for gestational diabetes mellitus: new evidence from China. Diabetes Care (2013) 2.89
Graphene-based composites. Chem Soc Rev (2011) 2.85
Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine (2005) 2.82
Growth of large-area and highly crystalline MoS2 thin layers on insulating substrates. Nano Lett (2012) 2.81
Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res (2008) 2.81
Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias. Brain (2011) 2.80
The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein. Mol Cell (2002) 2.80
Complete reconstitution of a highly reducing iterative polyketide synthase. Science (2009) 2.68
Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology (2010) 2.64
The SNPlex genotyping system: a flexible and scalable platform for SNP genotyping. J Biomol Tech (2005) 2.64
Immune protection of nonhuman primates against Ebola virus with single low-dose adenovirus vectors encoding modified GPs. PLoS Med (2006) 2.64
Heterologous envelope immunogens contribute to AIDS vaccine protection in rhesus monkeys. J Virol (2004) 2.63
Replication-defective adenovirus serotype 5 vectors elicit durable cellular and humoral immune responses in nonhuman primates. J Virol (2005) 2.61
Pathway analysis of coronary atherosclerosis. Physiol Genomics (2005) 2.59
Factors affecting catastrophic health expenditure and impoverishment from medical expenses in China: policy implications of universal health insurance. Bull World Health Organ (2012) 2.53
Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer. Nat Med (2011) 2.49
The evolution of dip-pen nanolithography. Angew Chem Int Ed Engl (2004) 2.49
Collateral density, remodeling, and VEGF-A expression differ widely between mouse strains. Physiol Genomics (2007) 2.46
Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Ann Neurol (2012) 2.45
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res (2008) 2.44
The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med (2008) 2.43
Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
Calibrating the end-Permian mass extinction. Science (2011) 2.41
Multiclade human immunodeficiency virus type 1 envelope immunogens elicit broad cellular and humoral immunity in rhesus monkeys. J Virol (2005) 2.40
China's rural-urban care gap shrank for chronic disease patients, but inequities persist. Health Aff (Millwood) (2010) 2.39
Acetylation of lysine 56 of histone H3 catalyzed by RTT109 and regulated by ASF1 is required for replisome integrity. J Biol Chem (2007) 2.38
Variations of oral microbiota are associated with pancreatic diseases including pancreatic cancer. Gut (2011) 2.38
Alternative splicing of cGMP-dependent protein kinase I in angiotensin-hypertension: novel mechanism for nitrate tolerance in vascular smooth muscle. Circ Res (2003) 2.35
Complete genome sequence analysis of Seneca Valley virus-001, a novel oncolytic picornavirus. J Gen Virol (2008) 2.31
Light regulates COP1-mediated degradation of HFR1, a transcription factor essential for light signaling in Arabidopsis. Plant Cell (2005) 2.31
Incidence of atypical nontraumatic diaphyseal fractures of the femur. J Bone Miner Res (2012) 2.29
In vitro derivation of functional insulin-producing cells from human embryonic stem cells. Cell Res (2007) 2.28
Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Res (2006) 2.26
Association between vitamin D and risk of colorectal cancer: a systematic review of prospective studies. J Clin Oncol (2011) 2.24
Multiple functions of Osterix are required for bone growth and homeostasis in postnatal mice. Proc Natl Acad Sci U S A (2010) 2.20
Interaction of Huntington disease protein with transcriptional activator Sp1. Mol Cell Biol (2002) 2.19
The effects of CES1A2 A(-816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease. Pharmacogenet Genomics (2014) 2.15
A role for Gcn5 in replication-coupled nucleosome assembly. Mol Cell (2010) 2.14
Polymer pen lithography. Science (2008) 2.14
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model. Cancer Cell (2009) 2.14
Comparative efficacy of neutralizing antibodies elicited by recombinant hemagglutinin proteins from avian H5N1 influenza virus. J Virol (2008) 2.14
Salivary transcriptomic biomarkers for detection of resectable pancreatic cancer. Gastroenterology (2009) 2.13
No significant association between the TP53 codon 72 polymorphism and breast cancer risk: a meta-analysis of 21 studies involving 24,063 subjects. Breast Cancer Res Treat (2010) 2.12
Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers. PLoS One (2010) 2.12
ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data. Nucleic Acids Res (2012) 2.11
Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
Structure-based stabilization of HIV-1 gp120 enhances humoral immune responses to the induced co-receptor binding site. PLoS Pathog (2009) 2.07
Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol (2005) 2.07
MRI-based finite-element analysis of left ventricular aneurysm. Am J Physiol Heart Circ Physiol (2005) 2.06
Helical myofiber orientation after myocardial infarction and left ventricular surgical restoration in sheep. J Thorac Cardiovasc Surg (2005) 2.06
Chloride intracellular channel-4 is a determinant of native collateral formation in skeletal muscle and brain. Circ Res (2009) 2.02
Obesity and risk of colorectal cancer: a systematic review of prospective studies. PLoS One (2013) 2.02
Electrically conductive and optically active porous silicon nanowires. Nano Lett (2009) 2.00
Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol (2009) 2.00
Efficient protein boosting after plasmid DNA or recombinant adenovirus immunization with HIV-1 vaccine constructs. Vaccine (2006) 1.99
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol (2009) 1.98
Functional characterization of DNAM-1 (CD226) interaction with its ligands PVR (CD155) and nectin-2 (PRR-2/CD112). Int Immunol (2004) 1.92
Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet (2012) 1.91
Protective role of ecto-5'-nucleotidase (CD73) in renal ischemia. J Am Soc Nephrol (2007) 1.90
Aspirin for primary prevention of cardiovascular events in patients with diabetes: A meta-analysis. Diabetes Res Clin Pract (2009) 1.90
MicroRNA-99a inhibits hepatocellular carcinoma growth and correlates with prognosis of patients with hepatocellular carcinoma. J Biol Chem (2011) 1.88
SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer. J Pathol (2013) 1.87
Tumor-associated microglia/macrophages enhance the invasion of glioma stem-like cells via TGF-β1 signaling pathway. J Immunol (2012) 1.86
Hypomethylation-linked activation of PAX2 mediates tamoxifen-stimulated endometrial carcinogenesis. Nature (2005) 1.86
Graphene-based materials: synthesis, characterization, properties, and applications. Small (2011) 1.85
G-protein-coupled receptor modulation of striatal CaV1.3 L-type Ca2+ channels is dependent on a Shank-binding domain. J Neurosci (2005) 1.84