Published in PLoS One on May 14, 2010
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res (2011) 5.83
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Efficient cellular fractionation improves RNA sequencing analysis of mature and nascent transcripts from human tissues. BMC Biotechnol (2013) 0.84
Transfer RNA detection by small RNA deep sequencing and disease association with myelodysplastic syndromes. BMC Genomics (2015) 0.84
Both endo-siRNAs and tRNA-derived small RNAs are involved in the differentiation of primitive eukaryote Giardia lamblia. Proc Natl Acad Sci U S A (2014) 0.83
Regulation of mammalian transcription and splicing by Nuclear RNAi. Nucleic Acids Res (2015) 0.83
Transcriptional targeting by microRNA-polycomb complexes: a novel route in cell fate determination. Cell Cycle (2012) 0.83
miR-125b induces cellular senescence in malignant melanoma. BMC Dermatol (2014) 0.82
Assessing the gene regulatory properties of Argonaute-bound small RNAs of diverse genomic origin. Nucleic Acids Res (2014) 0.82
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Identification of nuclear-enriched miRNAs during mouse granulopoiesis. J Hematol Oncol (2014) 0.81
A comprehensive repertoire of tRNA-derived fragments in prostate cancer. Oncotarget (2016) 0.79
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Impact of gastro-oesophageal reflux on microRNA expression, location and function. BMC Gastroenterol (2013) 0.79
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Selective microRNA-Offset RNA expression in human embryonic stem cells. PLoS One (2015) 0.78
The Role of microRNAs in Stemness of Cancer Stem Cells. Oncol Rev (2013) 0.78
RNA-Seq of the nucleolus reveals abundant SNORD44-derived small RNAs. PLoS One (2014) 0.78
Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif. PLoS One (2014) 0.78
MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells. Nucleic Acids Res (2015) 0.78
Gene processing control loops suggested by sequencing, splicing, and RNA folding. BMC Bioinformatics (2010) 0.78
Nuclear microRNAs in normal hemopoiesis and cancer. J Hematol Oncol (2017) 0.78
Identification of General and Heart-Specific miRNAs in Sheep (Ovis aries). PLoS One (2015) 0.77
The nuclear and organellar tRNA-derived RNA fragment population in Arabidopsis thaliana is highly dynamic. Nucleic Acids Res (2016) 0.77
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microPIR2: a comprehensive database for human-mouse comparative study of microRNA-promoter interactions. Database (Oxford) (2014) 0.77
tRF2Cancer: A web server to detect tRNA-derived small RNA fragments (tRFs) and their expression in multiple cancers. Nucleic Acids Res (2016) 0.77
Schizophrenia-Associated MIR204 Regulates Noncoding RNAs and Affects Neurotransmitter and Ion Channel Gene Sets. PLoS One (2015) 0.76
MicroRNAs in the Host Response to Viral Infections of Veterinary Importance. Front Vet Sci (2016) 0.76
Molecular organization of the 5S rDNA gene type II in elasmobranchs. RNA Biol (2015) 0.75
Conserved and highly expressed tRNA derived fragments in zebrafish. BMC Mol Biol (2015) 0.75
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Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases. Genomics Inform (2015) 0.75
Nuclear Compartmentalization Contributes to Stage-Specific Gene Expression Control in Trypanosoma cruzi. Front Cell Dev Biol (2017) 0.75
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Predictive biophysical modeling and understanding of the dynamics of mRNA translation and its evolution. Nucleic Acids Res (2016) 0.75
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Connecting the dots of RNA-directed DNA methylation in Arabidopsis thaliana. Chromosome Res (2014) 0.75
Long non-coding RNA SeT and miR-155 regulate the Tnfα gene allelic expression profile. PLoS One (2017) 0.75
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The UCSC Genome Browser Database. Nucleic Acids Res (2003) 32.84
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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev (2003) 17.64
Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science (2002) 17.04
Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Mol Cell (2004) 16.10
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Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell (2006) 15.12
Argonaute HITS-CLIP decodes microRNA-mRNA interaction maps. Nature (2009) 14.07
Identification of microRNAs of the herpesvirus family. Nat Methods (2005) 12.98
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. Genome Res (2008) 10.18
Discovering microRNAs from deep sequencing data using miRDeep. Nat Biotechnol (2008) 10.17
Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs. Genome Res (2007) 9.61
Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell (2005) 9.27
MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. Dev Cell (2007) 7.66
MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc Natl Acad Sci U S A (2008) 6.38
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
A human snoRNA with microRNA-like functions. Mol Cell (2008) 5.84
A hexanucleotide element directs microRNA nuclear import. Science (2007) 5.71
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Argonaute-1 directs siRNA-mediated transcriptional gene silencing in human cells. Nat Struct Mol Biol (2006) 4.93
A human, ATP-independent, RISC assembly machine fueled by pre-miRNA. Genes Dev (2005) 4.55
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Angiogenin cleaves tRNA and promotes stress-induced translational repression. J Cell Biol (2009) 4.07
Argonaute loading improves the 5' precision of both MicroRNAs and their miRNA* strands in flies. Curr Biol (2008) 4.07
An Argonaute transports siRNAs from the cytoplasm to the nucleus. Science (2008) 3.86
A microRNA catalog of the developing chicken embryo identified by a deep sequencing approach. Genome Res (2008) 3.74
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The primary transcription product of a silkworm alanine tRNA gene: identification of in vitro sites of initiation, termination and processing. Cell (1979) 2.66
Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries. PLoS One (2009) 2.37
MicroRNA-206 colocalizes with ribosome-rich regions in both the nucleolus and cytoplasm of rat myogenic cells. Proc Natl Acad Sci U S A (2006) 2.15
Fluorescence correlation spectroscopy and fluorescence cross-correlation spectroscopy reveal the cytoplasmic origination of loaded nuclear RISC in vivo in human cells. Nucleic Acids Res (2008) 2.01
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Identification of 20 microRNAs from Oryza sativa. Nucleic Acids Res (2004) 1.61
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Comprehensive thermodynamic analysis of 3' double-nucleotide overhangs neighboring Watson-Crick terminal base pairs. Nucleic Acids Res (2006) 1.54
High-resolution profiling and discovery of planarian small RNAs. Proc Natl Acad Sci U S A (2009) 1.53
Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia. Nucleic Acids Res (2008) 1.52
The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs. Nat Cell Biol (2009) 1.48
Plant dicistronic tRNA-snoRNA genes: a new mode of expression of the small nucleolar RNAs processed by RNase Z. EMBO J (2003) 1.47
A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Trends Cell Biol (2008) 1.44
Synthesis and maturation of Xenopus laevis methionine tRNA gene transcripts in homologous cell-free extracts. J Biol Chem (1982) 1.27
Identification of newly transcribed RNA. Curr Protoc Mol Biol (2007) 1.02
Conservation of a masked nuclear export activity of La proteins and its effects on tRNA maturation. Mol Cell Biol (2007) 0.98
Microarray analysis of differentially expressed genes between nasopharyngeal carcinoma cell lines 5-8F and 6-10B. Cancer Genet Cytogenet (2010) 0.84
The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science (2007) 11.15
starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res (2013) 4.33
Rtt109 acetylates histone H3 lysine 56 and functions in DNA replication. Science (2007) 4.12
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Salivary microRNA: discovery, characterization, and clinical utility for oral cancer detection. Clin Cancer Res (2009) 3.86
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Salivary proteomic and genomic biomarkers for primary Sjögren's syndrome. Arthritis Rheum (2007) 2.90
Salivary proteomics for oral cancer biomarker discovery. Clin Cancer Res (2008) 2.81
Complete reconstitution of a highly reducing iterative polyketide synthase. Science (2009) 2.68
Liver-enriched transcription factors regulate microRNA-122 that targets CUTL1 during liver development. Hepatology (2010) 2.64
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Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
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MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. Biochem Biophys Res Commun (2009) 1.73
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Identification of 20 microRNAs from Oryza sativa. Nucleic Acids Res (2004) 1.61
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Evidence that a West-East admixed population lived in the Tarim Basin as early as the early Bronze Age. BMC Biol (2010) 1.55
Rtt106p is a histone chaperone involved in heterochromatin-mediated silencing. Proc Natl Acad Sci U S A (2005) 1.55
Injection of recombinant human type VII collagen corrects the disease phenotype in a murine model of dystrophic epidermolysis bullosa. Mol Ther (2008) 1.54
Epidemiologic study of the predisposing factors in erythema toxicum neonatorum. Dermatology (2005) 1.53
Stress-induced tRNA-derived RNAs: a novel class of small RNAs in the primitive eukaryote Giardia lamblia. Nucleic Acids Res (2008) 1.52
Rice embryogenic calli express a unique set of microRNAs, suggesting regulatory roles of microRNAs in plant post-embryogenic development. FEBS Lett (2006) 1.47
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Extremely low genetic diversity indicating the endangered status of Ranodon sibiricus (Amphibia: Caudata) and implications for phylogeography. PLoS One (2012) 1.44
piRNA, the new non-coding RNA, is aberrantly expressed in human cancer cells. Clin Chim Acta (2011) 1.43
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer. PLoS One (2010) 1.43
Mitochondrial DNA evidence for a diversified origin of workers building First Emperor of China. PLoS One (2008) 1.40
Impulse inhibition in people with Internet addiction disorder: electrophysiological evidence from a Go/NoGo study. Neurosci Lett (2010) 1.40
piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells. Cancer Lett (2011) 1.39
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The Relationship of Parathyroidectomy and Bisphosphonates With Fracture Risk in Primary Hyperparathyroidism: An Observational Study. Ann Intern Med (2016) 1.38
HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration. J Neurosci (2011) 1.38
A novel role for histone chaperones CAF-1 and Rtt106p in heterochromatin silencing. EMBO J (2007) 1.37
A prospective, randomized clinical trial comparing plasmakinetic resection of the prostate with holmium laser enucleation of the prostate based on a 2-year followup. J Urol (2012) 1.37
Visualizing individual nitrogen dopants in monolayer graphene. Science (2011) 1.35
Systemic disease-induced salivary biomarker profiles in mouse models of melanoma and non-small cell lung cancer. PLoS One (2009) 1.35
High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells. FEBS Lett (2010) 1.34
The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. PLoS Genet (2009) 1.32
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease. Environ Health Perspect (2011) 1.30
Precursor or sequela: pathological disorders in people with Internet addiction disorder. PLoS One (2011) 1.30
Prevalidation of salivary biomarkers for oral cancer detection. Cancer Epidemiol Biomarkers Prev (2012) 1.30
Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently. J Biol Chem (2002) 1.29
A new method for purification of recombinant human alpha-synuclein in Escherichia coli. Protein Expr Purif (2005) 1.28
Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays. Proteomics (2011) 1.27
Mitogenomic perspectives on the origin and phylogeny of living amphibians. Syst Biol (2005) 1.26
The Schizosaccharomyces pombe mgU6-47 gene is required for 2'-O-methylation of U6 snRNA at A41. Nucleic Acids Res (2002) 1.26
Expression analysis of phytohormone-regulated microRNAs in rice, implying their regulation roles in plant hormone signaling. FEBS Lett (2009) 1.26