Structural basis for broad and potent neutralization of HIV-1 by antibody VRC01.

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Published in Science on July 08, 2010

Authors

Tongqing Zhou1, Ivelin Georgiev, Xueling Wu, Zhi-Yong Yang, Kaifan Dai, Andrés Finzi, Young Do Kwon, Johannes F Scheid, Wei Shi, Ling Xu, Yongping Yang, Jiang Zhu, Michel C Nussenzweig, Joseph Sodroski, Lawrence Shapiro, Gary J Nabel, John R Mascola, Peter D Kwong

Author Affiliations

1: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH), Bethesda, MD 20892, USA.

Associated clinical trials:

VRC-HIVMAB060-00-AB (VRC01) in People With Chronic HIV Infection Undergoing Analytical Treatment Interruption | NCT02471326

Evaluating the Safety, Pharmacokinetics, and Antiviral Activity of a Human Monoclonal Antibody (VRC01) in HIV-Infected Adults Undergoing a Brief Treatment Interruption | NCT02463227

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