Published in Blood on November 17, 2010
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev (2011) 1.89
Marrow failure: a window into ribosome biology. Blood (2014) 1.06
Ribosome biogenesis in skeletal development and the pathogenesis of skeletal disorders. Biochim Biophys Acta (2013) 0.93
Inherited bone marrow failure syndromes in adolescents and young adults. Ann Med (2014) 0.88
Of blood, bones, and ribosomes: is Swachman-Diamond syndrome a ribosomopathy? Genes Dev (2011) 0.86
Modulation of osteoclast differentiation and bone resorption by Rho GTPases. Small GTPases (2014) 0.80
Ribosomopathies: mechanisms of disease. Clin Med Insights Blood Disord (2014) 0.80
Integrative Analysis of Transcriptomic and Epigenomic Data to Reveal Regulation Patterns for BMD Variation. PLoS One (2015) 0.80
Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs. Nucleic Acids Res (2016) 0.77
The ever-expanding conundrum of primary osteoporosis: aetiopathogenesis, diagnosis, and treatment. Ital J Pediatr (2014) 0.77
Functional relevance for associations between osteoporosis and genetic variants. PLoS One (2017) 0.75
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet (2002) 7.12
Activation of antibacterial autophagy by NADPH oxidases. Proc Natl Acad Sci U S A (2009) 3.87
Stem cell depletion through epidermal deletion of Rac1. Science (2005) 3.26
Requirements for Vav guanine nucleotide exchange factors and Rho GTPases in FcgammaR- and complement-mediated phagocytosis. Immunity (2006) 2.57
Time scale and other invariants of integrative mechanical behavior in living cells. Phys Rev E Stat Nonlin Soft Matter Phys (2003) 2.42
NADPH oxidase complex and IBD candidate gene studies: identification of a rare variant in NCF2 that results in reduced binding to RAC2. Gut (2011) 2.26
Rac1 is the small GTPase responsible for regulating the neutrophil chemotaxis compass. Blood (2004) 2.06
Shwachman-Diamond syndrome: report from an international conference. J Pediatr (2002) 1.99
Targeting cell surface receptors with ligand-conjugated nanocrystals. J Am Chem Soc (2002) 1.82
Common variants in ZNF365 are associated with both mammographic density and breast cancer risk. Nat Genet (2011) 1.77
The N. gonorrhoeae type IV pilus stimulates mechanosensitive pathways and cytoprotection through a pilT-dependent mechanism. PLoS Biol (2005) 1.50
Rac1 links leading edge and uropod events through Rho and myosin activation during chemotaxis. Blood (2006) 1.49
Design of radiation tolerant materials via interface engineering. Adv Mater (2013) 1.47
A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J Cell Sci (2009) 1.45
Rac1 and Rac2 differentially regulate actin free barbed end formation downstream of the fMLP receptor. J Cell Biol (2007) 1.41
The phosphatidylserine receptor TIM4 utilizes integrins as coreceptors to effect phagocytosis. Mol Biol Cell (2014) 1.38
Molecular epidemiology of avian leukosis virus subgroup J in layer flocks in China. J Clin Microbiol (2012) 1.33
Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome. Ann N Y Acad Sci (2011) 1.33
Genetic ablation of Rac1 in cartilage results in chondrodysplasia. Dev Biol (2007) 1.26
Rac2 is required for the formation of neutrophil extracellular traps. J Leukoc Biol (2011) 1.25
Role of osteopontin in neutrophil function. Immunology (2007) 1.25
Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation. Am J Physiol Heart Circ Physiol (2008) 1.24
Identifying the relative contributions of Rac1 and Rac2 to osteoclastogenesis. J Bone Miner Res (2008) 1.21
Vav proteins in neutrophils are required for FcgammaR-mediated signaling to Rac GTPases and nicotinamide adenine dinucleotide phosphate oxidase component p40(phox). J Immunol (2006) 1.21
Filamin A regulates cell spreading and survival via beta1 integrins. Exp Cell Res (2007) 1.20
Chemotactic signaling pathways in neutrophils: from receptor to actin assembly. Crit Rev Oral Biol Med (2002) 1.13
Human neutrophils coordinate chemotaxis by differential activation of Rac1 and Rac2. J Immunol (2009) 1.10
Diabetes and periodontal diseases: interplay and links. Curr Diabetes Rev (2011) 1.10
Unraveling the complex genetic model for cystic fibrosis: pleiotropic effects of modifier genes on early cystic fibrosis-related morbidities. Hum Genet (2013) 1.10
Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis. Am J Physiol Lung Cell Mol Physiol (2009) 1.09
Neural crest cell-specific deletion of Rac1 results in defective cell-matrix interactions and severe craniofacial and cardiovascular malformations. Dev Biol (2010) 1.06
Cytoskeletal remodeling in leukocyte function. Curr Opin Hematol (2004) 1.06
Novel sequences of subgroup J avian leukosis viruses associated with hemangioma in Chinese layer hens. Virol J (2011) 1.06
Mammographic breast density and breast cancer: evidence of a shared genetic basis. Cancer Res (2012) 1.03
Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E. Exp Toxicol Pathol (2008) 1.03
CD44 is a phagocytic receptor. Blood (2006) 1.03
The axonal repellent, Slit2, inhibits directional migration of circulating neutrophils. J Leukoc Biol (2009) 1.02
Critical role for voltage-dependent anion channel 2 in infectious bursal disease virus-induced apoptosis in host cells via interaction with VP5. J Virol (2011) 1.02
Polarization and directed migration of murine neutrophils is dependent on cell surface expression of CD44. Cell Immunol (2005) 1.00
Shwachman-Diamond syndrome is associated with low-turnover osteoporosis. Bone (2007) 0.99
A 205-nucleotide deletion in the 3' untranslated region of avian leukosis virus subgroup J, currently emergent in China, contributes to its pathogenicity. J Virol (2012) 0.99
The role of Rac1 and Rac2 in bacterial killing. Cell Immunol (2005) 0.98
Single nucleotide polymorphisms that increase expression of the guanosine triphosphatase RAC1 are associated with ulcerative colitis. Gastroenterology (2011) 0.97
The chloride channel ClC-4 co-localizes with cystic fibrosis transmembrane conductance regulator and may mediate chloride flux across the apical membrane of intestinal epithelia. J Biol Chem (2001) 0.97
Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. J Immunol (2008) 0.96
Control of neutrophil pseudopods by fluid shear: role of Rho family GTPases. Am J Physiol Cell Physiol (2004) 0.96
Filamin A regulates monocyte migration through Rho small GTPases during osteoclastogenesis. J Bone Miner Res (2010) 0.95
Gelsolin mediates collagen phagocytosis through a rac-dependent step. Mol Biol Cell (2003) 0.95
Macrophage mesenchymal migration requires podosome stabilization by filamin A. J Biol Chem (2012) 0.94
Rac regulates PtdInsP₃ signaling and the chemotactic compass through a redox-mediated feedback loop. Blood (2011) 0.94
Development of an indirect ELISA for serological detection of reticuloendotheliosis virus using the gp90 protein expressed in Pichia pastoris. J Virol Methods (2011) 0.94
MicroRNA 181 suppresses porcine reproductive and respiratory syndrome virus (PRRSV) infection by targeting PRRSV receptor CD163. J Virol (2013) 0.93
The major outer sheath protein of Treponema denticola selectively inhibits Rac1 activation in murine neutrophils. Cell Microbiol (2007) 0.93
Innate immunity and arthritis: neutrophil Rac and toll-like receptor 4 expression define outcomes in infection-triggered arthritis. Arthritis Rheum (2005) 0.92
Employing heavy metal-free colloidal quantum dots in solution-processed white light-emitting diodes. Nano Lett (2010) 0.91
Oral neutrophil transcriptome changes result in a pro-survival phenotype in periodontal diseases. PLoS One (2013) 0.90
Highly efficient quantum-dot light-emitting diodes with DNA-CTMA as a combined hole-transporting and electron-blocking layer. ACS Nano (2009) 0.90
Role of Rac1 in a bleomycin-induced scleroderma model using fibroblast-specific Rac1-knockout mice. Arthritis Rheum (2008) 0.89
Effects of helium implantation on the tensile properties and microstructure of Ni73P27 metallic glass nanostructures. Nano Lett (2014) 0.89
Timing of neutrophil tissue repopulation predicts restoration of innate immune protection in a murine bone marrow transplantation model. Blood (2006) 0.89
Induction of de novo subcortical actin filament assembly by Treponema denticola major outer sheath protein. Infect Immun (2004) 0.88
Identification of a novel percent mammographic density locus at 12q24. Hum Mol Genet (2012) 0.88
Aquaporin 9 phosphorylation mediates membrane localization and neutrophil polarization. J Leukoc Biol (2011) 0.87
Pivotal Advance: Phospholipids determine net membrane surface charge resulting in differential localization of active Rac1 and Rac2. J Leukoc Biol (2010) 0.87
Naturally occurring mutations at residues 253 and 284 in VP2 contribute to the cell tropism and virulence of very virulent infectious bursal disease virus. Antiviral Res (2009) 0.87
Nitric oxide enhances osteoclastogenesis possibly by mediating cell fusion. Nitric Oxide (2009) 0.87
A computationally guided protein-interaction screen uncovers coiled-coil interactions involved in vesicular trafficking. J Mol Biol (2009) 0.86
Genetic diversity and phylogenetic analysis of glycoprotein gp85 of avian leukosis virus subgroup J wild-bird isolates from Northeast China. Arch Virol (2014) 0.86
Expression and translocation of fluorescent-tagged p21-activated kinase-binding domain and PH domain of protein kinase B during murine neutrophil chemotaxis. J Leukoc Biol (2007) 0.86
Toxic effects of zearalenone and alpha-zearalenol on the regulation of steroidogenesis and testosterone production in mouse Leydig cells. Toxicol In Vitro (2006) 0.86
Differential expression of microRNAs in avian leukosis virus subgroup J-induced tumors. Vet Microbiol (2012) 0.86
Avian leukosis virus subgroup A and B infection in wild birds of Northeast China. Vet Microbiol (2013) 0.86
Modulation of human neutrophil functions in vitro by Treponema denticola major outer sheath protein. Infect Immun (2006) 0.86
Upregulation of centromere protein H is associated with progression of renal cell carcinoma. J Mol Histol (2015) 0.85
Requirement for Vav proteins in post-recruitment neutrophil cytotoxicity in IgG but not complement C3-dependent injury. J Immunol (2008) 0.85
Filamin A protects cells against force-induced apoptosis by stabilizing talin- and vinculin-containing cell adhesions. FASEB J (2013) 0.85
Proteome analysis of silk gland proteins from the silkworm, Bombyx mori. Proteomics (2006) 0.85
Genetic diversity and phylogenetic analysis of glycoprotein GP85 of ALV-J isolates from Mainland China between 1999 and 2010: coexistence of two extremely different subgroups in layers. Vet Microbiol (2011) 0.85
Identification of the pathogens associated with skin ulceration and peristome tumescence in cultured sea cucumbers Apostichopus japonicus (Selenka). J Invertebr Pathol (2010) 0.84
Development of an antigen-capture ELISA for the detection of avian leukosis virus p27 antigen. J Virol Methods (2012) 0.84
Development and application of a multiplex PCR method for rapid differential detection of subgroup A, B, and J avian leukosis viruses. J Clin Microbiol (2013) 0.84
Development and application of real-time PCR for detection of subgroup J avian leukosis virus. J Clin Microbiol (2012) 0.84
Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages. J Biol Chem (2009) 0.84
A hyperactive neutrophil phenotype in patients with refractory periodontitis. J Periodontol (2007) 0.84
A single amino acid V4I substitution in VP1 attenuates virulence of very virulent infectious bursal disease virus (vvIBDV) in SPF chickens and increases replication in CEF cells. Virology (2013) 0.84
Recombinant Kluyveromyces lactis expressing highly pathogenic porcine reproductive and respiratory syndrome virus GP5 elicits mucosal and cell-mediated immune responses in mice. J Vet Sci (2013) 0.84
Engagement of soluble resistance-related calcium binding protein (sorcin) with foot-and-mouth disease virus (FMDV) VP1 inhibits type I interferon response in cells. Vet Microbiol (2013) 0.83
Molecular characterization and phylogenetic analysis of the reticuloendotheliosis virus isolated from wild birds in Northeast China. Vet Microbiol (2013) 0.83
Osteopetrosis mutation R444L causes endoplasmic reticulum retention and misprocessing of vacuolar H+-ATPase a3 subunit. J Biol Chem (2012) 0.83
Treponema denticola major outer sheath protein induces actin assembly at free barbed ends by a PIP2-dependent uncapping mechanism in fibroblasts. PLoS One (2011) 0.83
Development of a loop-mediated isothermal amplification method for rapid detection of reticuloendotheliosis virus. J Virol Methods (2010) 0.83
Rac2-deficiency leads to exacerbated and protracted colitis in response to Citrobacter rodentium infection. PLoS One (2013) 0.83
Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine. Drug Metab Dispos (2008) 0.83
Blockade of TLR2 inhibits Porphyromonas gingivalis suppression of mineralized matrix formation by human dental pulp stem cells. J Endod (2011) 0.83
Detection and molecular characterization of recombinant avian leukosis viruses in commercial egg-type chickens in China. Avian Pathol (2011) 0.83