Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response.
|
Science
|
2006
|
18.74
|
2
|
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know.
|
J Clin Endocrinol Metab
|
2010
|
13.29
|
3
|
Endogenous antimicrobial peptides and skin infections in atopic dermatitis.
|
N Engl J Med
|
2002
|
9.01
|
4
|
The antimicrobial peptide cathelicidin protects the urinary tract against invasive bacterial infection.
|
Nat Med
|
2006
|
5.20
|
5
|
Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism.
|
J Clin Invest
|
2007
|
3.82
|
6
|
HIF-1alpha expression regulates the bactericidal capacity of phagocytes.
|
J Clin Invest
|
2005
|
3.77
|
7
|
Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea.
|
Nat Med
|
2007
|
3.75
|
8
|
AMPed up immunity: how antimicrobial peptides have multiple roles in immune defense.
|
Trends Immunol
|
2009
|
3.40
|
9
|
Cytokine milieu of atopic dermatitis skin subverts the innate immune response to vaccinia virus.
|
Immunity
|
2006
|
3.39
|
10
|
Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury.
|
Nat Med
|
2009
|
3.32
|
11
|
An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.
|
J Clin Invest
|
2003
|
3.19
|
12
|
Recognition of hyaluronan released in sterile injury involves a unique receptor complex dependent on Toll-like receptor 4, CD44, and MD-2.
|
J Biol Chem
|
2007
|
2.82
|
13
|
Hyaluronan fragments stimulate endothelial recognition of injury through TLR4.
|
J Biol Chem
|
2004
|
2.81
|
14
|
IOM committee members respond to Endocrine Society vitamin D guideline.
|
J Clin Endocrinol Metab
|
2012
|
2.75
|
15
|
Histone acetylation in keratinocytes enables control of the expression of cathelicidin and CD14 by 1,25-dihydroxyvitamin D3.
|
J Invest Dermatol
|
2007
|
2.45
|
16
|
Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation.
|
FASEB J
|
2006
|
2.41
|
17
|
Neuroendocrine nicotinic receptor activation increases susceptibility to bacterial infections by suppressing antimicrobial peptide production.
|
Cell Host Microbe
|
2010
|
2.39
|
18
|
Administration of oral vitamin D induces cathelicidin production in atopic individuals.
|
J Allergy Clin Immunol
|
2008
|
2.33
|
19
|
Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin.
|
FASEB J
|
2006
|
2.33
|
20
|
Statins enhance formation of phagocyte extracellular traps.
|
Cell Host Microbe
|
2010
|
2.28
|
21
|
Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum.
|
J Allergy Clin Immunol
|
2009
|
2.20
|
22
|
Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection.
|
J Invest Dermatol
|
2005
|
2.19
|
23
|
The antimicrobial protein REG3A regulates keratinocyte proliferation and differentiation after skin injury.
|
Immunity
|
2012
|
2.17
|
24
|
Selective killing of vaccinia virus by LL-37: implications for eczema vaccinatum.
|
J Immunol
|
2004
|
2.16
|
25
|
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin.
|
J Invest Dermatol
|
2010
|
2.13
|
26
|
D-alanylation of teichoic acids promotes group a streptococcus antimicrobial peptide resistance, neutrophil survival, and epithelial cell invasion.
|
J Bacteriol
|
2005
|
2.04
|
27
|
Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers.
|
J Invest Dermatol
|
2007
|
2.02
|
28
|
Interplay between antibacterial effectors: a macrophage antimicrobial peptide impairs intracellular Salmonella replication.
|
Proc Natl Acad Sci U S A
|
2004
|
2.00
|
29
|
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury.
|
J Biol Chem
|
2009
|
1.91
|
30
|
Cathelicidin deficiency predisposes to eczema herpeticum.
|
J Allergy Clin Immunol
|
2006
|
1.88
|
31
|
Control of the innate epithelial antimicrobial response is cell-type specific and dependent on relevant microenvironmental stimuli.
|
Immunology
|
2006
|
1.88
|
32
|
N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution.
|
Mol Cell Biol
|
2007
|
1.87
|
33
|
Dermatan sulfate: new functions from an old glycosaminoglycan.
|
Glycobiology
|
2002
|
1.87
|
34
|
Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens.
|
J Immunol
|
2005
|
1.86
|
35
|
Plasmacytoid dendritic cells sense skin injury and promote wound healing through type I interferons.
|
J Exp Med
|
2010
|
1.85
|
36
|
Antimicrobial peptides and the skin immune defense system.
|
J Allergy Clin Immunol
|
2008
|
1.85
|
37
|
Cutaneous defense mechanisms by antimicrobial peptides.
|
J Invest Dermatol
|
2005
|
1.85
|
38
|
Neutrophil-derived cathelicidin protects from neointimal hyperplasia.
|
Sci Transl Med
|
2011
|
1.84
|
39
|
Neutrophil-derived cathelicidin promotes adhesion of classical monocytes.
|
Circ Res
|
2013
|
1.80
|
40
|
The 2011 Dietary Reference Intakes for Calcium and Vitamin D: what dietetics practitioners need to know.
|
J Am Diet Assoc
|
2011
|
1.80
|
41
|
M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition.
|
J Innate Immun
|
2009
|
1.80
|
42
|
Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide.
|
J Immunol
|
2003
|
1.79
|
43
|
Activation of TLR2 by a small molecule produced by Staphylococcus epidermidis increases antimicrobial defense against bacterial skin infections.
|
J Invest Dermatol
|
2010
|
1.79
|
44
|
The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury.
|
J Invest Dermatol
|
2008
|
1.79
|
45
|
Structure-function relationships among human cathelicidin peptides: dissociation of antimicrobial properties from host immunostimulatory activities.
|
J Immunol
|
2005
|
1.78
|
46
|
Tight junction defects in patients with atopic dermatitis.
|
J Allergy Clin Immunol
|
2010
|
1.77
|
47
|
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions.
|
Sci Transl Med
|
2011
|
1.74
|
48
|
Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense.
|
J Immunol
|
2004
|
1.74
|
49
|
Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice.
|
J Clin Invest
|
2007
|
1.72
|
50
|
Antimicrobial and protease inhibitory functions of the human cathelicidin (hCAP18/LL-37) prosequence.
|
J Invest Dermatol
|
2003
|
1.70
|
51
|
Cathelicidins, essential gene-encoded mammalian antibiotics.
|
J Mol Med (Berl)
|
2002
|
1.68
|
52
|
Ultraviolet radiation damages self noncoding RNA and is detected by TLR3.
|
Nat Med
|
2012
|
1.68
|
53
|
Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation, and epidermal organelles.
|
J Invest Dermatol
|
2013
|
1.68
|
54
|
Cathelin-related antimicrobial peptide differentially regulates T- and B-cell function.
|
Eur J Immunol
|
2011
|
1.67
|
55
|
The mammalian ionic environment dictates microbial susceptibility to antimicrobial defense peptides.
|
FASEB J
|
2006
|
1.66
|
56
|
Keratinocyte production of cathelicidin provides direct activity against bacterial skin pathogens.
|
Infect Immun
|
2005
|
1.60
|
57
|
Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgaris.
|
J Invest Dermatol
|
2008
|
1.55
|
58
|
Interleukin-10 downregulates anti-microbial peptide expression in atopic dermatitis.
|
J Invest Dermatol
|
2005
|
1.54
|
59
|
Bcl-3 acts as an innate immune modulator by controlling antimicrobial responses in keratinocytes.
|
J Invest Dermatol
|
2009
|
1.52
|
60
|
The microbiome extends to subepidermal compartments of normal skin.
|
Nat Commun
|
2013
|
1.52
|
61
|
Expression of LL-37 by human gastric epithelial cells as a potential host defense mechanism against Helicobacter pylori.
|
Gastroenterology
|
2003
|
1.51
|
62
|
Keratinocytes store the antimicrobial peptide cathelicidin in lamellar bodies.
|
J Invest Dermatol
|
2005
|
1.48
|
63
|
M protein and hyaluronic acid capsule are essential for in vivo selection of covRS mutations characteristic of invasive serotype M1T1 group A Streptococcus.
|
MBio
|
2010
|
1.47
|
64
|
Cathelicidin anti-microbial peptide expression in sweat, an innate defense system for the skin.
|
J Invest Dermatol
|
2002
|
1.47
|
65
|
Adrenocorticotropin hormone stimulates interleukin-18 expression in human HaCaT keratinocytes.
|
J Invest Dermatol
|
2007
|
1.45
|
66
|
Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization.
|
J Immunol
|
2007
|
1.42
|
67
|
The molecular pathology of rosacea.
|
J Dermatol Sci
|
2009
|
1.41
|
68
|
Induction of the antimicrobial peptide CRAMP in the blood-brain barrier and meninges after meningococcal infection.
|
Infect Immun
|
2006
|
1.41
|
69
|
Lack of neutrophil-derived CRAMP reduces atherosclerosis in mice.
|
Circ Res
|
2012
|
1.38
|
70
|
Fermentation of Propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant Staphylococcus aureus.
|
PLoS One
|
2013
|
1.38
|
71
|
Genetic variants in thymic stromal lymphopoietin are associated with atopic dermatitis and eczema herpeticum.
|
J Allergy Clin Immunol
|
2010
|
1.38
|
72
|
Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis.
|
J Cell Biol
|
2007
|
1.36
|
73
|
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris.
|
J Invest Dermatol
|
2009
|
1.35
|
74
|
Antimicrobial peptides: old molecules with new ideas.
|
J Invest Dermatol
|
2011
|
1.34
|
75
|
Cathelicidins and innate defense against invasive bacterial infection.
|
Scand J Infect Dis
|
2003
|
1.33
|
76
|
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
|
Invest Ophthalmol Vis Sci
|
2007
|
1.33
|
77
|
A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence.
|
FASEB J
|
2008
|
1.31
|
78
|
IL-17A enhances vitamin D3-induced expression of cathelicidin antimicrobial peptide in human keratinocytes.
|
J Immunol
|
2008
|
1.31
|
79
|
Antimicrobial peptides.
|
J Am Acad Dermatol
|
2005
|
1.30
|
80
|
Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection.
|
Proc Natl Acad Sci U S A
|
2005
|
1.26
|
81
|
Collagen synthesis is suppressed in dermal fibroblasts by the human antimicrobial peptide LL-37.
|
J Invest Dermatol
|
2008
|
1.26
|
82
|
Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression.
|
J Invest Dermatol
|
2009
|
1.23
|
83
|
Neutrophil differentiation into a unique hybrid population exhibiting dual phenotype and functionality of neutrophils and dendritic cells.
|
Blood
|
2013
|
1.23
|
84
|
Functions of the skin microbiota in health and disease.
|
Semin Immunol
|
2013
|
1.22
|
85
|
Structural and sequence motifs in dermatan sulfate for promoting fibroblast growth factor-2 (FGF-2) and FGF-7 activity.
|
J Biol Chem
|
2004
|
1.22
|
86
|
Heterogeneous expression of human cathelicidin hCAP18/LL-37 in inflammatory bowel diseases.
|
Eur J Gastroenterol Hepatol
|
2006
|
1.21
|
87
|
Cathelicidin-related antimicrobial peptide is required for effective lung mucosal immunity in Gram-negative bacterial pneumonia.
|
J Immunol
|
2012
|
1.20
|
88
|
Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin.
|
J Immunol
|
2008
|
1.20
|
89
|
TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes.
|
J Invest Dermatol
|
2010
|
1.18
|
90
|
Antimicrobial peptides in human skin disease.
|
Eur J Dermatol
|
2007
|
1.17
|
91
|
Staphylococcus epidermidis antimicrobial delta-toxin (phenol-soluble modulin-gamma) cooperates with host antimicrobial peptides to kill group A Streptococcus.
|
PLoS One
|
2010
|
1.17
|
92
|
M1T1 group A streptococcal pili promote epithelial colonization but diminish systemic virulence through neutrophil extracellular entrapment.
|
J Mol Med (Berl)
|
2009
|
1.17
|
93
|
Antimicrobial peptides and the skin immune defense system.
|
J Allergy Clin Immunol
|
2009
|
1.16
|
94
|
Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS.
|
Mol Immunol
|
2009
|
1.16
|
95
|
Neonatal skin in mice and humans expresses increased levels of antimicrobial peptides: innate immunity during development of the adaptive response.
|
Pediatr Res
|
2003
|
1.15
|
96
|
Flagellin stimulates protective lung mucosal immunity: role of cathelicidin-related antimicrobial peptide.
|
J Immunol
|
2010
|
1.15
|
97
|
Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7).
|
J Biol Chem
|
2002
|
1.11
|
98
|
Developmental switch of intestinal antimicrobial peptide expression.
|
J Exp Med
|
2008
|
1.11
|
99
|
Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid.
|
J Invest Dermatol
|
2010
|
1.09
|
100
|
Cathelicidin antimicrobial peptide LL-37 in psoriasis enables keratinocyte reactivity against TLR9 ligands.
|
J Invest Dermatol
|
2011
|
1.09
|
101
|
Neutrophil antimicrobial defense against Staphylococcus aureus is mediated by phagolysosomal but not extracellular trap-associated cathelicidin.
|
J Leukoc Biol
|
2009
|
1.08
|
102
|
Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel.
|
J Am Acad Dermatol
|
2013
|
1.08
|
103
|
Activation of epidermal toll-like receptor 2 enhances tight junction function: implications for atopic dermatitis and skin barrier repair.
|
J Invest Dermatol
|
2012
|
1.08
|
104
|
S100A15, an antimicrobial protein of the skin: regulation by E. coli through Toll-like receptor 4.
|
J Invest Dermatol
|
2007
|
1.08
|
105
|
Development of atopic dermatitis-like skin disease from the chronic loss of epidermal caspase-8.
|
Proc Natl Acad Sci U S A
|
2010
|
1.07
|
106
|
Vitamin D in allergic disease: shedding light on a complex problem.
|
J Allergy Clin Immunol
|
2013
|
1.06
|
107
|
Antimicrobial peptides in the pathogenesis of psoriasis.
|
J Dermatol
|
2012
|
1.06
|
108
|
Antimicrobial peptides, skin infections, and atopic dermatitis.
|
Semin Cutan Med Surg
|
2008
|
1.06
|
109
|
Sebocytes express functional cathelicidin antimicrobial peptides and can act to kill propionibacterium acnes.
|
J Invest Dermatol
|
2008
|
1.06
|
110
|
Migration studies and histology of injectable microspheres of different sizes in mice.
|
Plast Reconstr Surg
|
2004
|
1.05
|
111
|
Propionibacterium acnes CAMP factor and host acid sphingomyelinase contribute to bacterial virulence: potential targets for inflammatory acne treatment.
|
PLoS One
|
2011
|
1.04
|
112
|
Innate immunity and antimicrobial defense systems in psoriasis.
|
Clin Dermatol
|
2007
|
1.04
|
113
|
Vaccination targeting a surface sialidase of P. acnes: implication for new treatment of acne vulgaris.
|
PLoS One
|
2008
|
1.04
|
114
|
The host defense peptide cathelicidin is required for NK cell-mediated suppression of tumor growth.
|
J Immunol
|
2009
|
1.04
|
115
|
Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer.
|
Cancer Res
|
2012
|
1.03
|
116
|
Histone H4 is a major component of the antimicrobial action of human sebocytes.
|
J Invest Dermatol
|
2009
|
1.03
|
117
|
The antimicrobial peptide cathelicidin modulates Clostridium difficile-associated colitis and toxin A-mediated enteritis in mice.
|
Gut
|
2012
|
1.02
|
118
|
Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin.
|
J Invest Dermatol
|
2012
|
1.02
|
119
|
Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins.
|
Biochemistry
|
2012
|
1.01
|
120
|
Staphylococcus aureus hijacks a skin commensal to intensify its virulence: immunization targeting β-hemolysin and CAMP factor.
|
J Invest Dermatol
|
2010
|
1.01
|
121
|
Reductions in claudin-1 may enhance susceptibility to herpes simplex virus 1 infections in atopic dermatitis.
|
J Allergy Clin Immunol
|
2011
|
1.01
|
122
|
Bioengineering a humanized acne microenvironment model: proteomics analysis of host responses to Propionibacterium acnes infection in vivo.
|
Proteomics
|
2008
|
1.01
|
123
|
Vitamin D and innate immunity.
|
Dermatol Ther
|
2010
|
1.01
|
124
|
Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection.
|
Microbes Infect
|
2010
|
0.99
|
125
|
Expression and secretion of cathelicidin antimicrobial peptides in murine mammary glands and human milk.
|
Pediatr Res
|
2004
|
0.99
|
126
|
FGF-10 and specific structural elements of dermatan sulfate size and sulfation promote maximal keratinocyte migration and cellular proliferation.
|
Wound Repair Regen
|
2009
|
0.99
|
127
|
Toll-like receptors in skin infections and inflammatory diseases.
|
Infect Disord Drug Targets
|
2008
|
0.99
|
128
|
Phagocytosis of different particulate dermal filler substances by human macrophages and skin cells.
|
Dermatol Surg
|
2002
|
0.97
|
129
|
Augmentation of cutaneous immune responses by ATP gamma S: purinergic agonists define a novel class of immunologic adjuvants.
|
J Immunol
|
2005
|
0.97
|
130
|
Cathelicidin antimicrobial peptides inhibit hyaluronan-induced cytokine release and modulate chronic allergic dermatitis.
|
J Immunol
|
2008
|
0.97
|
131
|
Acute ethanol exposure disrupts VEGF receptor cell signaling in endothelial cells.
|
Am J Physiol Heart Circ Physiol
|
2008
|
0.97
|
132
|
Staphylococcus epidermidis in the human skin microbiome mediates fermentation to inhibit the growth of Propionibacterium acnes: implications of probiotics in acne vulgaris.
|
Appl Microbiol Biotechnol
|
2013
|
0.96
|
133
|
Rosacea as a disease of cathelicidins and skin innate immunity.
|
J Investig Dermatol Symp Proc
|
2011
|
0.96
|
134
|
Antimicrobial peptides and the skin.
|
Expert Opin Biol Ther
|
2004
|
0.95
|
135
|
Expanding the roles of antimicrobial peptides in skin: alarming and arming keratinocytes.
|
J Invest Dermatol
|
2007
|
0.95
|
136
|
Hyaluronan digestion controls DC migration from the skin.
|
J Clin Invest
|
2014
|
0.95
|
137
|
Streptococcal inhibitor of complement promotes innate immune resistance phenotypes of invasive M1T1 group A Streptococcus.
|
J Innate Immun
|
2010
|
0.94
|
138
|
Impairment of innate immune killing mechanisms by bacteriostatic antibiotics.
|
FASEB J
|
2007
|
0.94
|
139
|
Differing effects of exogenous or endogenous cathelicidin on macrophage toll-like receptor signaling.
|
Immunol Cell Biol
|
2009
|
0.93
|
140
|
The vitamin D pathway: a new target for control of the skin's immune response?
|
Exp Dermatol
|
2008
|
0.93
|
141
|
ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis.
|
J Innate Immun
|
2009
|
0.93
|
142
|
A novel role of a lipid species, sphingosine-1-phosphate, in epithelial innate immunity.
|
Mol Cell Biol
|
2012
|
0.93
|
143
|
Innate immune defense system of the skin.
|
Vet Dermatol
|
2013
|
0.91
|
144
|
Why is rosacea considered to be an inflammatory disorder? The primary role, clinical relevance, and therapeutic correlations of abnormal innate immune response in rosacea-prone skin.
|
J Drugs Dermatol
|
2012
|
0.91
|
145
|
Granulysin-derived peptides demonstrate antimicrobial and anti-inflammatory effects against Propionibacterium acnes.
|
J Invest Dermatol
|
2005
|
0.90
|
146
|
Quantitative proteomes and in vivo secretomes of progressive and regressive UV-induced fibrosarcoma tumor cells: mimicking tumor microenvironment using a dermis-based cell-trapped system linked to tissue chamber.
|
Proteomics
|
2007
|
0.90
|
147
|
The essentiality of alpha-2-macroglobulin in human salivary innate immunity against new H1N1 swine origin influenza A virus.
|
Proteomics
|
2010
|
0.90
|
148
|
Structure and function of the human skin microbiome.
|
Trends Microbiol
|
2013
|
0.89
|
149
|
Protecting the boundary: the sentinel role of host defense peptides in the skin.
|
Cell Mol Life Sci
|
2011
|
0.89
|
150
|
Cyclooxygenase-2 enhances antimicrobial peptide expression and killing of Staphylococcus aureus.
|
J Immunol
|
2010
|
0.89
|
151
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