Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging.

Single-photon-emission computed tomography (SPECT) with technetium-99m sestamibi in the diagnosis of small breast cancer and axillary lymph node involvement. World J Surg (2011) 1.41

Multicolored stain-free histopathology with coherent Raman imaging. Lab Invest (2012) 1.22

Differential diagnosis of breast cancer using quantitative, label-free and molecular vibrational imaging. Biomed Opt Express (2011) 0.93

Coherent fiber supercontinuum for biophotonics. Laser Photon Rev (2013) 0.87

Detection of lipid-rich prostate circulating tumour cells with coherent anti-Stokes Raman scattering microscopy. BMC Cancer (2012) 0.84

Raman imaging at biological interfaces: applications in breast cancer diagnosis. Mol Cancer (2013) 0.83

Pump-probe nonlinear phase dispersion spectroscopy. Opt Express (2013) 0.81

Nonlinear interferometric vibrational imaging for fast label-free visualization of molecular domains in skin. Anal Bioanal Chem (2011) 0.81

Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer. BMC Cancer (2016) 0.81

Stain-free histopathology by programmable supercontinuum pulses. Nat Photonics (2016) 0.80

Coherent anti-Stokes Raman scattering microscopy: overcoming technical barriers for clinical translation. J Biophotonics (2013) 0.78

Optical coherence tomography for rapid tissue screening and directed histological sectioning. Anal Cell Pathol (Amst) (2012) 0.76

Raman Spectroscopic Analysis Reveals Abnormal Fatty Acid Composition in Tumor Micro- and Macroenvironments in Human Breast and Rat Mammary Cancer. Sci Rep (2016) 0.75

In vivo imaging of the tumor and its associated microenvironment using combined CARS / 2-photon microscopy. Intravital (2015) 0.75

Optical parametrically gated microscopy in scattering media. Opt Express (2014) 0.75

The Gold Nanorod-Biology Interface: From Proteins to Cells to Tissue. Curr Phys Chem (2013) 0.75

Dispersion-based stimulated Raman scattering spectroscopy, holography, and optical coherence tomography. Opt Express (2016) 0.75

Enhanced detection of metastatic prostate cancer cells in human plasma with lipid bodies staining. BMC Cancer (2014) 0.75

Concurrence of extracellular vesicle enrichment and metabolic switch visualized label-free in the tumor microenvironment. Sci Adv (2017) 0.75

Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes Dev (2003) 11.29

In vivo endoscopic optical biopsy with optical coherence tomography. Science (1997) 6.74

Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A (2005) 5.96

Coherent anti-stokes Raman scattering microscopy: chemical imaging for biology and medicine. Annu Rev Anal Chem (Palo Alto Calif) (2008) 5.13

Positron emission tomography provides molecular imaging of biological processes. Proc Natl Acad Sci U S A (2000) 5.04

Prospects for in vivo Raman spectroscopy. Phys Med Biol (2000) 3.32

Diagnosing breast cancer by using Raman spectroscopy. Proc Natl Acad Sci U S A (2005) 2.95

Histological grading of breast carcinomas: a study of interobserver agreement. Hum Pathol (1995) 2.63

Intraoperative evaluation of breast tumor margins with optical coherence tomography. Cancer Res (2009) 2.28

Three-dimensional nonlinear optical endoscopy. J Biomed Opt (2007) 1.79

Nonlinear interferometric vibrational imaging. Phys Rev Lett (2004) 1.75

Towards a practical Fourier transform infrared chemical imaging protocol for cancer histopathology. Anal Bioanal Chem (2007) 1.62

Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer. Breast Cancer Res Treat (2004) 1.62

Coherent anti-Stokes Raman scattering imaging of lipids in cancer metastasis. BMC Cancer (2009) 1.41

Real-time Raman system for in vivo disease diagnosis. J Biomed Opt (2005) 1.36

Disease recognition by infrared and Raman spectroscopy. J Biophotonics (2009) 1.35

A comparison of the histopathology of premalignant and malignant mammary gland lesions induced in sexually immature rats with those occurring in the human. Lab Invest (2000) 1.32

Optical frequency up-conversion by supercontinuum-free widely-tunable fiber-optic Cherenkov radiation. Opt Express (2009) 1.30

Rat models of premalignant breast disease. J Mammary Gland Biol Neoplasia (2000) 1.20

Characterization of human breast biopsy specimens with near-IR Raman spectroscopy. Anal Chem (1994) 1.20

High speed nonlinear interferometric vibrational analysis of lipids by spectral decomposition. Anal Chem (2010) 1.13

High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett (2006) 1.13

Raman spectroscopy can differentiate malignant tumors from normal breast tissue and detect early neoplastic changes in a mouse model. Biopolymers (2008) 1.10

Model-based biological Raman spectral imaging. J Cell Biochem Suppl (2002) 1.10

A comparative Raman and CARS imaging study of colon tissue. J Biophotonics (2009) 1.10

Chirped coherent anti-stokes Raman scattering for high spectral resolution spectroscopy and chemically selective imaging. J Phys Chem B (2006) 1.06

Clinical feasibility of microscopically-guided breast needle biopsy using a fiber-optic probe with computer-aided detection. Technol Cancer Res Treat (2009) 1.00

Chasing lipids in health and diseases by coherent anti-Stokes Raman scattering microscopy. Vib Spectrosc (2009) 0.99

Classification of premalignant and malignant lesions developing in the rat mammary gland after injection of sexually immature rats with 1-methyl-1-nitrosourea. J Mammary Gland Biol Neoplasia (2000) 0.98

High-Speed Nonlinear Interferometric Vibrational Imaging of Biological Tissue With Comparison to Raman Microscopy. IEEE J Quantum Electron (2009) 0.90

Chirped coherent anti-Stokes Raman scattering as a high-spectral- and spatial-resolution microscopy. Opt Lett (2007) 0.83

The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76

Absolute comparison of simulated and experimental protein-folding dynamics. Nature (2002) 5.68

Folding at the speed limit. Nature (2003) 4.23

Ten-microsecond molecular dynamics simulation of a fast-folding WW domain. Biophys J (2008) 3.81

Genomic analyses identify distinct patterns of selection in domesticated pigs and Tibetan wild boars. Nat Genet (2013) 3.41

Optical coherence tomography: a review of clinical development from bench to bedside. J Biomed Opt (2007) 3.18

An experimental survey of the transition between two-state and downhill protein folding scenarios. Proc Natl Acad Sci U S A (2008) 2.57

Folding lambda-repressor at its speed limit. Biophys J (2004) 2.44

Context-dependent contributions of backbone hydrogen bonding to beta-sheet folding energetics. Nature (2004) 2.44

Intraoperative evaluation of breast tumor margins with optical coherence tomography. Cancer Res (2009) 2.28

Structure-function-folding relationship in a WW domain. Proc Natl Acad Sci U S A (2006) 2.28

Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation. Proc Natl Acad Sci U S A (2003) 2.15

Rate-temperature relationships in lambda-repressor fragment lambda 6-85 folding. Biochemistry (2004) 2.11

Optical micro-scale mapping of dynamic biomechanical tissue properties. Opt Express (2008) 2.02

Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes (2012) 1.91

Engineered microsphere contrast agents for optical coherence tomography. Opt Lett (2003) 1.91

Fourier transform light scattering of inhomogeneous and dynamic structures. Phys Rev Lett (2008) 1.90

Biomechanical properties of in vivo human skin from dynamic optical coherence elastography. IEEE Trans Biomed Eng (2009) 1.89

Optical coherence elastography of engineered and developing tissue. Tissue Eng (2006) 1.86

In vivo three-dimensional optical coherence elastography. Opt Express (2011) 1.84

Plasmon-resonant gold nanorods as low backscattering albedo contrast agents for optical coherence tomography. Opt Express (2006) 1.81

Protein folding stability and dynamics imaged in a living cell. Nat Methods (2010) 1.77

Spectroscopic spectral-domain optical coherence microscopy. Opt Lett (2006) 1.77

Nonlinear interferometric vibrational imaging. Phys Rev Lett (2004) 1.75

Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding. Proc Natl Acad Sci U S A (2010) 1.75

Imaging magnetically labeled cells with magnetomotive optical coherence tomography. Opt Lett (2005) 1.73

Effect of Agouti-related protein in regulation of the hypothalamic-pituitary-thyroid axis in the melanocortin 4 receptor knockout mouse. Endocrinology (2004) 1.71

Therapy insight: Use of melanocortin antagonists in the treatment of cachexia in chronic disease. Nat Clin Pract Endocrinol Metab (2006) 1.70

Phase-resolved magnetomotive OCT for imaging nanomolar concentrations of magnetic nanoparticles in tissues. Opt Express (2008) 1.67

Optical probes and techniques for molecular contrast enhancement in coherence imaging. J Biomed Opt (2005) 1.67

Compressive holography. Opt Express (2009) 1.66

In vivo magnetomotive optical molecular imaging using targeted magnetic nanoprobes. Proc Natl Acad Sci U S A (2010) 1.65

Noninvasive in vivo optical detection of biofilm in the human middle ear. Proc Natl Acad Sci U S A (2012) 1.63

Exploring the energy landscape of a small RNA hairpin. J Am Chem Soc (2006) 1.62

Optical coherence tomography: feasibility for basic research and image-guided surgery of breast cancer. Breast Cancer Res Treat (2004) 1.62

An extended dynamical hydration shell around proteins. Proc Natl Acad Sci U S A (2007) 1.59

Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130. Endocrinology (2009) 1.58

Computational adaptive optics for broadband optical interferometric tomography of biological tissue. Proc Natl Acad Sci U S A (2012) 1.57

Handheld optical coherence tomography scanner for primary care diagnostics. IEEE Trans Biomed Eng (2010) 1.56

Multimodal biomedical imaging with asymmetric single-walled carbon nanotube/iron oxide nanoparticle complexes. Nano Lett (2007) 1.55

Magnetomotive nanoparticle transducers for optical rheology of viscoelastic materials. Opt Express (2009) 1.53

Engineering a beta-sheet protein toward the folding speed limit. J Phys Chem B (2005) 1.49

Kinetics are probe-dependent during downhill folding of an engineered lambda6-85 protein. Proc Natl Acad Sci U S A (2005) 1.49

Computational design and experimental testing of the fastest-folding β-sheet protein. J Mol Biol (2010) 1.46

High-resolution three-dimensional imaging of biofilm development using optical coherence tomography. J Biomed Opt (2006) 1.46

Heterogeneous folding of the trpzip hairpin: full atom simulation and experiment. J Mol Biol (2004) 1.46

Acoustomotive optical coherence elastography for measuring material mechanical properties. Opt Lett (2009) 1.45

Dynamic spectral-domain optical coherence elastography for tissue characterization. Opt Express (2010) 1.44

Spectroscopic optical coherence elastography. Opt Express (2010) 1.43

Computational methods for analysis of human breast tumor tissue in optical coherence tomography images. J Biomed Opt (2006) 1.42

Full-range k-domain linearization in spectral-domain optical coherence tomography. Appl Opt (2011) 1.41

Microscopic imaging and spectroscopy with scattered light. Annu Rev Biomed Eng (2010) 1.41

Speckle reduction by I-divergence regularization in optical coherence tomography. J Opt Soc Am A Opt Image Sci Vis (2005) 1.41

Optoelectronic Switching of a Carbon Nanotube Chiral Junction Imaged with Nanometer Spatial Resolution. ACS Nano (2015) 1.40

Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice. Am J Pathol (2005) 1.37

Tuning lambda6-85 towards downhill folding at its melting temperature. J Mol Biol (2007) 1.36

Comparative performance analysis of time-frequency distributions for spectroscopic optical coherence tomography. Appl Opt (2005) 1.35

Regulation of central melanocortin signaling by interleukin-1 beta. Endocrinology (2007) 1.34

Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate. Biochemistry (2004) 1.33

Detection-dependent kinetics as a probe of folding landscape microstructure. J Am Chem Soc (2004) 1.33

Three-dimensional optical coherence tomography of the embryonic murine cardiovascular system. J Biomed Opt (2006) 1.33

Stabilization of continuum generation from normally dispersive nonlinear optical fibers for a tunable broad bandwidth source for optical coherence tomography. Opt Lett (2007) 1.32

Inverse scattering for optical coherence tomography. J Opt Soc Am A Opt Image Sci Vis (2006) 1.32

Real-time in vivo computed optical interferometric tomography. Nat Photonics (2013) 1.31

Role of leptin and melanocortin signaling in uremia-associated cachexia. J Clin Invest (2005) 1.30

Resonant acoustic spectroscopy of soft tissues using embedded magnetomotive nanotransducers and optical coherence tomography. Phys Med Biol (2010) 1.30

Optical frequency up-conversion by supercontinuum-free widely-tunable fiber-optic Cherenkov radiation. Opt Express (2009) 1.30

Scalar generalized nonlinear Schrödinger equation-quantified continuum generation in an all-normal dispersion photonic crystal fiber for broadband coherent optical sources. Opt Express (2010) 1.30

Non-invasive optical interferometry for the assessment of biofilm growth in the middle ear. Biomed Opt Express (2010) 1.29

Projected index computed tomography. Opt Lett (2003) 1.29

An atlas of DNA methylomes in porcine adipose and muscle tissues. Nat Commun (2012) 1.28

Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns. Science (2011) 1.27

The transition state transit time of WW domain folding is controlled by energy landscape roughness. J Chem Phys (2009) 1.27

Tuning the heterogeneous early folding dynamics of phosphoglycerate kinase. J Mol Biol (2003) 1.26

Nonparaxial vector-field modeling of optical coherence tomography and interferometric synthetic aperture microscopy. J Opt Soc Am A Opt Image Sci Vis (2007) 1.25

Ghrelin treatment causes increased food intake and retention of lean body mass in a rat model of cancer cachexia. Endocrinology (2007) 1.25

Autofocus algorithm for dispersion correction in optical coherence tomography. Appl Opt (2003) 1.25

Digital algorithm for dispersion correction in optical coherence tomography for homogeneous and stratified media. Appl Opt (2003) 1.24

Obesity-induced inflammation in white adipose tissue is attenuated by loss of melanocortin-3 receptor signaling. Endocrinology (2007) 1.24

Ghrelin treatment of chronic kidney disease: improvements in lean body mass and cytokine profile. Endocrinology (2007) 1.23

Near-infrared dyes as contrast-enhancing agents for spectroscopic optical coherence tomography. Opt Lett (2004) 1.23

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice. Metabolism (2012) 1.22

Localized waveguide formation in germanosilicate fiber transmitting femtosecond IR pulses. J Opt Soc Am B (2008) 1.22

Inflammation-induced lethargy is mediated by suppression of orexin neuron activity. J Neurosci (2011) 1.22

Ground tit genome reveals avian adaptation to living at high altitudes in the Tibetan plateau. Nat Commun (2013) 1.20