Published in Proc Natl Acad Sci U S A on December 19, 2007
Water in cavity-ligand recognition. J Am Chem Soc (2010) 1.63
Correlated structural kinetics and retarded solvent dynamics at the metalloprotease active site. Nat Struct Mol Biol (2011) 1.35
Dissecting the THz spectrum of liquid water from first principles via correlations in time and space. Proc Natl Acad Sci U S A (2010) 1.18
Temperature dependence of protein folding kinetics in living cells. Proc Natl Acad Sci U S A (2012) 1.11
Site-specific hydration dynamics in the nonpolar core of a molten globule by dynamic nuclear polarization of water. J Am Chem Soc (2011) 1.05
Quantitative chemical imaging and unsupervised analysis using hyperspectral coherent anti-Stokes Raman scattering microscopy. Anal Chem (2013) 1.05
Two-dimensional Raman-terahertz spectroscopy of water. Proc Natl Acad Sci U S A (2013) 1.00
Long-range protein-water dynamics in hyperactive insect antifreeze proteins. Proc Natl Acad Sci U S A (2012) 0.97
Evidence of functional protein dynamics from X-ray crystallographic ensembles. PLoS Comput Biol (2010) 0.95
Novel determinants of the neuronal Cl(-) concentration. J Physiol (2014) 0.94
Structure and dynamics of protein waters revealed by radiolysis and mass spectrometry. Proc Natl Acad Sci U S A (2012) 0.91
Evidence for water structuring forces between surfaces. Curr Opin Colloid Interface Sci (2011) 0.90
Simulation-based fitting of protein-protein interaction potentials to SAXS experiments. Biophys J (2008) 0.90
Fast protein folding kinetics. Q Rev Biophys (2014) 0.86
Hydration water and bulk water in proteins have distinct properties in radial distributions calculated from 105 atomic resolution crystal structures. J Phys Chem B (2008) 0.86
The effects of alpha-helical structure and cyanylated cysteine on each other. J Phys Chem B (2010) 0.85
Crowding induced collective hydration of biological macromolecules over extended distances. J Am Chem Soc (2013) 0.85
Folding domain B of protein A on a dynamically partitioned free energy landscape. Proc Natl Acad Sci U S A (2008) 0.85
Thermal stability of lysozyme as a function of ion concentration: a reappraisal of the relationship between the Hofmeister series and protein stability. Protein Sci (2013) 0.85
Vibrational spectroscopy of water in hydrated lipid multi-bilayers. I. Infrared spectra and ultrafast pump-probe observables. J Chem Phys (2011) 0.84
Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces. Proc Natl Acad Sci U S A (2013) 0.84
Solvation dynamics of biomolecules: modeling and terahertz experiments. HFSP J (2008) 0.84
Water Dynamics in the Hydration Shells of Biomolecules. Chem Rev (2017) 0.83
Antifouling glycocalyx-mimetic peptoids. J Am Chem Soc (2013) 0.82
Evidence of protein collective motions on the picosecond timescale. Biophys J (2011) 0.82
Profiling of dynamics in protein-lipid-water systems: a time-resolved fluorescence study of a model membrane protein with the label BADAN at specific membrane depths. Eur Biophys J (2009) 0.81
Dielectric relaxation dynamics of water in model membranes probed by terahertz spectroscopy. Biophys J (2009) 0.80
The role of structured water in mediating general anesthetic action on alpha4beta2 nAChR. Phys Chem Chem Phys (2010) 0.80
Effects of surface functionalization on the adsorption of human serum albumin onto nanoparticles - a fluorescence correlation spectroscopy study. Beilstein J Nanotechnol (2014) 0.79
Pyroglutamate and O-linked glycan determine functional production of anti-IL17A and anti-IL22 peptide-antibody bispecific genetic fusions. J Biol Chem (2012) 0.78
Energy dissipation of nanoconfined hydration layer: long-range hydration on the hydrophilic solid surface. Sci Rep (2014) 0.78
Detailed study of the dielectric function of a lysozyme solution studied with molecular dynamics simulations. Eur Biophys J (2015) 0.78
Changes of water hydrogen bond network with different externalities. Int J Mol Sci (2015) 0.78
Do hydration dynamics follow the structural perturbation during thermal denaturation of a protein: a terahertz absorption study. Biophys J (2011) 0.78
Functional importance of short-range binding and long-range solvent interactions in helical antifreeze peptides. Biophys J (2012) 0.77
Aligning experimental and theoretical anisotropic B-factors: water models, normal-mode analysis methods, and metrics. J Phys Chem B (2014) 0.77
The glassy state of crambin and the THz time scale protein-solvent fluctuations possibly related to protein function. BMC Biophys (2014) 0.76
Cholesterol enhances surface water diffusion of phospholipid bilayers. J Chem Phys (2014) 0.76
Hydration dynamics in a partially denatured ensemble of the globular protein human alpha-lactalbumin investigated with molecular dynamics simulations. Biophys J (2008) 0.76
Protein structural and surface water rearrangement constitute major events in the earliest aggregation stages of tau. Proc Natl Acad Sci U S A (2015) 0.76
Solvent-Slaved Dynamic Processes Observed by Tryptophan Phosphorescence of Human Serum Albumin. Biophys J (2017) 0.75
The hydrogen-bond network of water supports propagating optical phonon-like modes. Nat Commun (2016) 0.75
Contraction-Induced Changes in Hydrogen Bonding of Muscle Hydration Water. J Phys Chem Lett (2014) 0.75
Hydrogen Bond Network of Water around Protein Investigated with Terahertz and Infrared Spectroscopy. Biophys J (2016) 0.75
Distinct Protein Hydration Water Species Defined by Spatially Resolved Spectra of Intermolecular Vibrations. J Phys Chem B (2017) 0.75
Signatures of solvation thermodynamics in spectra of intermolecular vibrations. J Chem Theory Comput (2017) 0.75
Protein states and proteinquakes. Proc Natl Acad Sci U S A (1985) 10.43
Protein hydration in solution: experimental observation by x-ray and neutron scattering. Proc Natl Acad Sci U S A (1998) 6.07
Folding at the speed limit. Nature (2003) 4.23
Direct observation of protein solvation and discrete disorder with experimental crystallographic phases. Science (1996) 2.65
Average protein density is a molecular-weight-dependent function. Protein Sci (2004) 2.62
Is the first hydration shell of lysozyme of higher density than bulk water? Proc Natl Acad Sci U S A (2002) 2.19
Cooperative water filling of a nonpolar protein cavity observed by high-pressure crystallography and simulation. Proc Natl Acad Sci U S A (2005) 1.91
Protein folding, stability, and solvation structure in osmolyte solutions. Biophys J (2005) 1.72
Diffusion of solvent around biomolecular solutes: a molecular dynamics simulation study. Biophys J (1998) 1.61
Dielectric modulation of biological water. Phys Rev Lett (2004) 1.40
Femtosecond dynamics of rubredoxin: tryptophan solvation and resonance energy transfer in the protein. Proc Natl Acad Sci U S A (2001) 1.33
Hydration-coupled dynamics in proteins studied by neutron scattering and NMR: the case of the typical EF-hand calcium-binding parvalbumin. Biophys J (1999) 1.30
Solvent-tuning the collapse and helix formation time scales of lambda(6-85)*. Protein Sci (2006) 1.16
Solute-induced retardation of water dynamics probed directly by terahertz spectroscopy. Proc Natl Acad Sci U S A (2006) 1.13
Probing the collective vibrational dynamics of a protein in liquid water by terahertz absorption spectroscopy. Protein Sci (2006) 1.06
Techniques: spectroscopy at a stretch. Nature (2005) 0.98
Large oxidation dependence observed in terahertz dielectric response for cytochrome c. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 0.96
High-resolution terahertz spectroscopy of crystalline trialanine: extreme sensitivity to beta-sheet structure and cocrystallized water. J Am Chem Soc (2006) 0.90
A loss-of-function RNA interference screen for molecular targets in cancer. Nature (2006) 8.11
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity (2004) 6.72
IRF4 addiction in multiple myeloma. Nature (2008) 6.27
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity (2002) 6.27
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma. J Exp Med (2003) 6.06
Absolute comparison of simulated and experimental protein-folding dynamics. Nature (2002) 5.68
Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial. Lancet Oncol (2013) 4.30
Folding at the speed limit. Nature (2003) 4.23
Ten-microsecond molecular dynamics simulation of a fast-folding WW domain. Biophys J (2008) 3.81
UV disinfection induces a VBNC state in Escherichia coli and Pseudomonas aeruginosa. Environ Sci Technol (2015) 3.26
Mental health system in China: history, recent service reform and future challenges. World Psychiatry (2011) 3.23
Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation. J Immunol (2004) 2.90
Pulse Pressure Variation Adjusted by Respiratory Changes in Pleural Pressure, Rather Than by Tidal Volume, Reliably Predicts Fluid Responsiveness in Patients With Acute Respiratory Distress Syndrome. Crit Care Med (2016) 2.64
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci (2010) 2.60
An experimental survey of the transition between two-state and downhill protein folding scenarios. Proc Natl Acad Sci U S A (2008) 2.57
Folding lambda-repressor at its speed limit. Biophys J (2004) 2.44
Context-dependent contributions of backbone hydrogen bonding to beta-sheet folding energetics. Nature (2004) 2.44
Targeted depletion of lymphotoxin-alpha-expressing TH1 and TH17 cells inhibits autoimmune disease. Nat Med (2009) 2.42
Remodeling of cardiac fiber structure after infarction in rats quantified with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2003) 2.30
Structure-function-folding relationship in a WW domain. Proc Natl Acad Sci U S A (2006) 2.28
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. Am J Pathol (2010) 2.20
Tuning the free-energy landscape of a WW domain by temperature, mutation, and truncation. Proc Natl Acad Sci U S A (2003) 2.15
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
Rate-temperature relationships in lambda-repressor fragment lambda 6-85 folding. Biochemistry (2004) 2.11
Awareness and attitudes of healthcare professionals in Wuhan, China to the reporting of adverse drug reactions. Chin Med J (Engl) (2004) 2.08
Regional ventricular wall thickening reflects changes in cardiac fiber and sheet structure during contraction: quantification with diffusion tensor MRI. Am J Physiol Heart Circ Physiol (2005) 1.91
The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity. J Biol Chem (2001) 1.82
Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: implications for rational therapy of restenosis. Circulation (2002) 1.77
Protein folding stability and dynamics imaged in a living cell. Nat Methods (2010) 1.77
Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding. Proc Natl Acad Sci U S A (2010) 1.75
Quantitative "magnetic resonance immunohistochemistry" with ligand-targeted (19)F nanoparticles. Magn Reson Med (2004) 1.68
Incidence and nature of cognitive decline over 1 year among HIV-infected former plasma donors in China. AIDS (2010) 1.66
Neurobehavioral effects of human immunodeficiency virus infection among former plasma donors in rural China. J Neurovirol (2008) 1.64
Cellular MRI contrast via coexpression of transferrin receptor and ferritin. Magn Reson Med (2006) 1.64
Exploring the energy landscape of a small RNA hairpin. J Am Chem Soc (2006) 1.62
Label-free imaging of metal-carbonyl complexes in live cells by Raman microspectroscopy. Angew Chem Int Ed Engl (2010) 1.62
Mechanoelectrical feedback as novel mechanism of cardiac electrical remodeling. Circulation (2007) 1.57
Cardioprotective effect of ocotillol, a derivate of pseudoginsenoside F11, on myocardial injury induced by isoproterenol in rats. Arzneimittelforschung (2007) 1.52
Engineering a beta-sheet protein toward the folding speed limit. J Phys Chem B (2005) 1.49
Kinetics are probe-dependent during downhill folding of an engineered lambda6-85 protein. Proc Natl Acad Sci U S A (2005) 1.49
Aggregation-induced dissociation of HCl(H2O)4 below 1 K: the smallest droplet of acid. Science (2009) 1.47
Computational design and experimental testing of the fastest-folding β-sheet protein. J Mol Biol (2010) 1.46
Heterogeneous folding of the trpzip hairpin: full atom simulation and experiment. J Mol Biol (2004) 1.46
Inducible re-expression of HEXIM1 causes physiological cardiac hypertrophy in the adult mouse. Cardiovasc Res (2013) 1.45
Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen. Proc Natl Acad Sci U S A (2008) 1.42
Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer. Am J Pathol (2002) 1.41
Optoelectronic Switching of a Carbon Nanotube Chiral Junction Imaged with Nanometer Spatial Resolution. ACS Nano (2015) 1.40
Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. Am J Psychiatry (2003) 1.40
Improved molecular imaging contrast agent for detection of human thrombus. Magn Reson Med (2003) 1.37
Tuning lambda6-85 towards downhill folding at its melting temperature. J Mol Biol (2007) 1.36
Harmonic phase MR tagging for direct quantification of Lagrangian strain in rat hearts after myocardial infarction. Magn Reson Med (2004) 1.35
Correlated structural kinetics and retarded solvent dynamics at the metalloprotease active site. Nat Struct Mol Biol (2011) 1.35
Folding thermodynamics and kinetics of YNMG RNA hairpins: specific incorporation of 8-bromoguanosine leads to stabilization by enhancement of the folding rate. Biochemistry (2004) 1.33
The role of aquaporin RWC3 in drought avoidance in rice. Plant Cell Physiol (2004) 1.33
Detection-dependent kinetics as a probe of folding landscape microstructure. J Am Chem Soc (2004) 1.33
Depression and suicidality in HIV/AIDS in China. J Affect Disord (2006) 1.32
MR tagging demonstrates quantitative differences in regional ventricular wall motion in mice, rats, and men. Am J Physiol Heart Circ Physiol (2006) 1.28
The transition state transit time of WW domain folding is controlled by energy landscape roughness. J Chem Phys (2009) 1.27
Protein native-state stabilization by placing aromatic side chains in N-glycosylated reverse turns. Science (2011) 1.27
Effect of varying amounts of a liquid nutritional supplement on the pharmacokinetics of posaconazole in healthy volunteers. Antimicrob Agents Chemother (2009) 1.27
Tuning the heterogeneous early folding dynamics of phosphoglycerate kinase. J Mol Biol (2003) 1.26
Paradoxical increase in ventricular torsion and systolic torsion rate in type I diabetic patients under tight glycemic control. J Am Coll Cardiol (2005) 1.25
Mass fractal dimension and the compactness of proteins. Phys Rev E Stat Nonlin Soft Matter Phys (2005) 1.24
Aminoglycoside resistance and susceptibility testing errors in Acinetobacter baumannii-calcoaceticus complex. J Clin Microbiol (2010) 1.23
Integrative structural modeling with small angle X-ray scattering profiles. BMC Struct Biol (2012) 1.22
Mental health in China: challenges and progress. Lancet (2012) 1.21
ORFDB: an information resource linking scientific content to a high-quality Open Reading Frame (ORF) collection. Nucleic Acids Res (2004) 1.19
On the extended beta-conformation propensity of polypeptides at high temperature. J Am Chem Soc (2003) 1.19
Dissecting the THz spectrum of liquid water from first principles via correlations in time and space. Proc Natl Acad Sci U S A (2010) 1.18
Manganese-enhanced magnetic resonance imaging (MEMRI) of mouse brain development. NMR Biomed (2004) 1.17
Carbapenem susceptibility testing errors using three automated systems, disk diffusion, Etest, and broth microdilution and carbapenem resistance genes in isolates of Acinetobacter baumannii-calcoaceticus complex. Antimicrob Agents Chemother (2011) 1.16
Solvent-tuning the collapse and helix formation time scales of lambda(6-85)*. Protein Sci (2006) 1.16
MicroRNA expression and its clinical implications in Ewing's sarcoma. Cell Prolif (2014) 1.14
Multidrug-resistant gram-negative bacteria colonization of healthy US military personnel in the US and Afghanistan. BMC Infect Dis (2013) 1.14
Early manifestation of alteration in cardiac function in dystrophin deficient mdx mouse using 3D CMR tagging. J Cardiovasc Magn Reson (2009) 1.13
High speed nonlinear interferometric vibrational analysis of lipids by spectral decomposition. Anal Chem (2010) 1.13
Neurobehavioral effects of HIV-1 infection in China and the United States: a pilot study. J Int Neuropsychol Soc (2007) 1.12
ModBase, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res (2013) 1.12
APOE epsilon4 and MBL-2 O/O genotypes are associated with neurocognitive impairment in HIV-infected plasma donors. AIDS (2010) 1.12
Upland rice and lowland rice exhibited different PIP expression under water deficit and ABA treatment. Cell Res (2006) 1.11
Temperature dependence of protein folding kinetics in living cells. Proc Natl Acad Sci U S A (2012) 1.11
Antifreeze glycoprotein activity correlates with long-range protein-water dynamics. J Am Chem Soc (2010) 1.10
Tobacco mosaic virus rods and spheres as supramolecular high-relaxivity MRI contrast agents. J Mater Chem B Mater Biol Med (2013) 1.10
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc Natl Acad Sci U S A (2012) 1.10
Amplitude of low-frequency oscillations in first-episode, treatment-naive patients with major depressive disorder: a resting-state functional MRI study. PLoS One (2012) 1.09
Identification and characterization of Bmi-1-responding element within the human p16 promoter. J Biol Chem (2010) 1.09
Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging. Cancer Res (2010) 1.09
Name change for schizophrenia. Schizophr Bull (2014) 1.08
Evaluating beta-turn mimics as beta-sheet folding nucleators. Proc Natl Acad Sci U S A (2009) 1.07
Tetracycline susceptibility testing and resistance genes in isolates of Acinetobacter baumannii-Acinetobacter calcoaceticus complex from a U.S. military hospital. Antimicrob Agents Chemother (2009) 1.06
The fast and the slow: folding and trapping of λ6-85. J Am Chem Soc (2011) 1.06
The formation of nitrogen-containing functional groups on carbon nanotube surfaces: a quantitative XPS and TPD study. Phys Chem Chem Phys (2010) 1.06
A survey of lambda repressor fragments from two-state to downhill folding. J Mol Biol (2010) 1.06
MicroRNA in intervertebral disc degeneration. Cell Prolif (2015) 1.05
Nontranscriptional regulation of SYK by the coactivator OCA-B is required at multiple stages of B cell development. Cell (2006) 1.05
Dual-modal magnetic resonance and fluorescence imaging of atherosclerotic plaques in vivo using VCAM-1 targeted tobacco mosaic virus. Nano Lett (2014) 1.04