Published in Aging (Albany NY) on November 01, 2010
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
The association of telomere length and cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev (2011) 3.29
Telomere length in early life predicts lifespan. Proc Natl Acad Sci U S A (2012) 2.74
Shortened telomere length is associated with increased risk of cancer: a meta-analysis. PLoS One (2011) 2.61
Exposure to violence during childhood is associated with telomere erosion from 5 to 10 years of age: a longitudinal study. Mol Psychiatry (2012) 2.37
Answering the ultimate question "what is the proximal cause of aging?". Aging (Albany NY) (2012) 2.04
Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study. Diabetes (2013) 1.91
Telomere length measurement-caveats and a critical assessment of the available technologies and tools. Mutat Res (2011) 1.79
Dyskeratosis congenita as a disorder of telomere maintenance. Mutat Res (2011) 1.35
Telomere length in white blood cell DNA and lung cancer: a pooled analysis of three prospective cohorts. Cancer Res (2014) 1.35
Autonomic and adrenocortical reactivity and buccal cell telomere length in kindergarten children. Psychosom Med (2011) 1.34
Early life stress and telomere length: investigating the connection and possible mechanisms: a critical survey of the evidence base, research methodology and basic biology. Bioessays (2012) 1.23
Cell biology of disease: Telomeropathies: an emerging spectrum disorder. J Cell Biol (2014) 1.07
Progeria, rapamycin and normal aging: recent breakthrough. Aging (Albany NY) (2011) 1.06
Psychiatric disorders and leukocyte telomere length: Underlying mechanisms linking mental illness with cellular aging. Neurosci Biobehav Rev (2015) 1.05
Controversial aspects of oncogene-induced senescence. Cell Cycle (2012) 1.04
Age-adjusted recipient pretransplantation telomere length and treatment-related mortality after hematopoietic stem cell transplantation. Blood (2012) 1.01
Telomere shortening in neurological disorders: an abundance of unanswered questions. Trends Neurosci (2014) 0.96
Telomeres and immune competency. Curr Opin Immunol (2012) 0.94
Telomere length and risk of glioma. Cancer Epidemiol (2013) 0.94
Automated Assay of Telomere Length Measurement and Informatics for 100,000 Subjects in the Genetic Epidemiology Research on Adult Health and Aging (GERA) Cohort. Genetics (2015) 0.94
Blood and dried blood spot telomere length measurement by qPCR: assay considerations. PLoS One (2013) 0.90
Telomere content and risk of second malignant neoplasm in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. Clin Cancer Res (2013) 0.87
Short leukocyte telomere length predicts incidence and progression of carotid atherosclerosis in American Indians: the Strong Heart Family Study. Aging (Albany NY) (2014) 0.87
Leukocyte telomere length variation due to DNA extraction method. BMC Res Notes (2014) 0.87
Maternal estriol concentrations in early gestation predict infant telomere length. J Clin Endocrinol Metab (2015) 0.85
Pesticide Use and Relative Leukocyte Telomere Length in the Agricultural Health Study. PLoS One (2015) 0.85
Shorter telomere length in peripheral blood leukocytes is associated with childhood autism. Sci Rep (2014) 0.85
Telomere Length as an Indicator of the Robustness of B- and T-Cell Response to Influenza in Older Adults. J Infect Dis (2015) 0.83
Number of Children and Telomere Length in Women: A Prospective, Longitudinal Evaluation. PLoS One (2016) 0.82
Telomere length, genetic variants and risk of squamous cell carcinoma of the head and neck in Southeast Chinese. Sci Rep (2016) 0.81
Leukocyte telomere length and diabetes status, duration, and control: the 1999-2002 National Health and Nutrition Examination Survey. BMC Endocr Disord (2015) 0.81
A role for sister telomere cohesion in telomere elongation by telomerase. Cell Cycle (2012) 0.81
Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes. J Immunol Res (2016) 0.80
Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging. Ageing Res Rev (2016) 0.80
I walk the line: how to tell MDS from other bone marrow failure conditions. Curr Hematol Malig Rep (2014) 0.79
Measuring relative telomere length: is tissue an issue? Aging (Albany NY) (2010) 0.79
The challenging world of cytopenias: distinguishing myelodysplastic syndromes from other disorders of marrow failure. Oncologist (2014) 0.77
A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition. Aging (Albany NY) (2015) 0.77
Impact of biological aging on arterial aging in American Indians: findings from the Strong Heart Family Study. Aging (Albany NY) (2016) 0.77
Fanconi anemia proteins in telomere maintenance. DNA Repair (Amst) (2016) 0.76
The assessment of CD146-based cell sorting and telomere length analysis for establishing the identity of mesenchymal stem cells in human umbilical cord. F1000Res (2014) 0.75
Novel evolutionary models and periodic charts in p- and q-individual chromosomes of auxiliary lymph node and buccal cells. Dis Markers (2013) 0.75
Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder. Transl Psychiatry (2015) 0.75
Cigarette smoking and telomere length: A systematic review of 84 studies and meta-analysis. Environ Res (2017) 0.75
Telomere reduction in human colorectal carcinoma and with ageing. Nature (1990) 11.24
Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci U S A (1992) 10.19
Telomere length measurement by a novel monochrome multiplex quantitative PCR method. Nucleic Acids Res (2009) 6.42
Telomeres and aging. Physiol Rev (2008) 4.79
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. Am J Hum Genet (1993) 4.78
Flow cytometry and FISH to measure the average length of telomeres (flow FISH). Nat Protoc (2006) 4.00
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood (2007) 3.86
Malignancies and survival patterns in the National Cancer Institute inherited bone marrow failure syndromes cohort study. Br J Haematol (2010) 3.09
Telomere length abnormalities occur early in the initiation of epithelial carcinogenesis. Clin Cancer Res (2004) 2.84
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita. Blood Cells Mol Dis (2001) 2.69
Syndromes of telomere shortening. Annu Rev Genomics Hum Genet (2009) 2.60
Constitutional short telomeres are strong genetic susceptibility markers for bladder cancer. Carcinogenesis (2005) 2.47
Dyskeratosis congenita. Hematol Oncol Clin North Am (2009) 2.45
Telomere length in different tissues of elderly patients. Mech Ageing Dev (2000) 2.45
The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging Cell (2009) 2.22
Telomere lengths are characteristic in each human individual. Exp Gerontol (2002) 2.13
The epidemiology of human telomeres: faults and promises. J Gerontol A Biol Sci Med Sci (2008) 2.11
Progressive telomere shortening in aplastic anemia. Blood (1998) 2.10
Chromosomal instability in ulcerative colitis is related to telomere shortening. Nat Genet (2002) 2.08
TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements. Blood (2008) 1.99
Analysis of telomeres in peripheral blood cells from patients with bone marrow failure. Pediatr Blood Cancer (2009) 1.71
Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mech Ageing Dev (2008) 1.69
Cancer and aging: the importance of telomeres in genome maintenance. Int J Biochem Cell Biol (2005) 1.64
Dyskeratosis congenita, stem cells and telomeres. Biochim Biophys Acta (2009) 1.62
Telomere length and genetic analyses in population-based studies of endometrial cancer risk. Cancer (2010) 1.61
Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet (1998) 1.39
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. Aging Cell (2007) 1.20
Abnormal telomere shortening in leucocytes of children with Shwachman-Diamond syndrome. Br J Haematol (2002) 1.19
Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma. Hepatology (2004) 1.19
Comparative analysis of telomere lengths and erosion with age in human epidermis and lingual epithelium. J Invest Dermatol (2002) 1.11
Investigation of telomere lengths measurement by quantitative real-time PCR to predict age. Leg Med (Tokyo) (2008) 1.05
Constitutive telomere length and gastric cancer risk: case-control analysis in Chinese Han population. Cancer Sci (2009) 1.05
Telomere length in fibroblasts and blood cells from healthy centenarians. Exp Cell Res (1999) 1.02
Abnormal telomere metabolism in Fanconi's anaemia correlates with genomic instability and the probability of developing severe aplastic anaemia. Br J Haematol (2003) 0.99
Comparison of telomere length of vocal folds with different tissues: a physiological measurement of vocal senescence. J Voice (2005) 0.86
Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer (2009) 6.00
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
Diagnosing and treating Diamond Blackfan anaemia: results of an international clinical consensus conference. Br J Haematol (2008) 4.41
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Cancer in dyskeratosis congenita. Blood (2009) 4.28
Hematotoxicity in workers exposed to low levels of benzene. Science (2004) 4.19
TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita. Am J Hum Genet (2008) 4.12
Cancer incidence in persons with Fanconi anemia. Blood (2002) 4.05
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood (2007) 3.86
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
The association of telomere length and cancer: a meta-analysis. Cancer Epidemiol Biomarkers Prev (2011) 3.29
Pathophysiology and management of inherited bone marrow failure syndromes. Blood Rev (2010) 3.24
Malignancies and survival patterns in the National Cancer Institute inherited bone marrow failure syndromes cohort study. Br J Haematol (2010) 3.09
Cell aging in relation to stress arousal and cardiovascular disease risk factors. Psychoneuroendocrinology (2005) 3.08
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Blood (2013) 2.82
The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy. Blood (2006) 2.82
Cancer risks in Fanconi anemia: findings from the German Fanconi Anemia Registry. Haematologica (2008) 2.72
A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of non-Hodgkin lymphoma. Clin Cancer Res (2009) 2.48
Dyskeratosis congenita. Hematol Oncol Clin North Am (2009) 2.45
Cancer survivorship--genetic susceptibility and second primary cancers: research strategies and recommendations. J Natl Cancer Inst (2006) 2.42
The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men. Aging (Albany NY) (2008) 2.35
Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells. Cancer Epidemiol Biomarkers Prev (2010) 2.34
The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer. Aging Cell (2009) 2.22
Germline mutations of regulator of telomere elongation helicase 1, RTEL1, in Dyskeratosis congenita. Hum Genet (2013) 2.10
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells. Nature (2011) 2.03
Fanconi anemia. Semin Hematol (2006) 1.99
Shwachman-Diamond syndrome: report from an international conference. J Pediatr (2002) 1.99
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita. Genes Dev (2011) 1.98
Risk of head and neck squamous cell cancer and death in patients with Fanconi anemia who did and did not receive transplants. Blood (2004) 1.97
International osteosarcoma incidence patterns in children and adolescents, middle ages and elderly persons. Int J Cancer (2009) 1.91
Telomere length is associated with disease severity and declines with age in dyskeratosis congenita. Haematologica (2011) 1.71
Incidence of neoplasia in Diamond Blackfan anemia: a report from the Diamond Blackfan Anemia Registry. Blood (2012) 1.69
p53 protein overexpression in bone marrow biopsies of patients with Shwachman-Diamond syndrome has a prevalence similar to that of patients with refractory anemia. Arch Pathol Lab Med (2002) 1.64
Cancer in Fanconi anemia. Blood (2003) 1.63
Endocrine abnormalities in patients with Fanconi anemia. J Clin Endocrinol Metab (2007) 1.63
Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions. Am J Hematol (2004) 1.56
The role of telomere biology in bone marrow failure and other disorders. Mech Ageing Dev (2007) 1.56
The association of telomere length and genetic variation in telomere biology genes. Hum Mutat (2010) 1.53
Telomere length in peripheral leukocyte DNA and gastric cancer risk. Cancer Epidemiol Biomarkers Prev (2009) 1.48
A prospective study of telomere length measured by monochrome multiplex quantitative PCR and risk of lung cancer. Lung Cancer (2011) 1.47
Ocular and orbital manifestations of the inherited bone marrow failure syndromes: Fanconi anemia and dyskeratosis congenita. Ophthalmology (2009) 1.47
Telomere length and cognitive function in community-dwelling elders: findings from the Health ABC Study. Neurobiol Aging (2009) 1.46
All in the family: disclosure of "unwanted" information to an adolescent to benefit a relative. Am J Med Genet A (2008) 1.44
Epidemiologic evidence for a role of telomere dysfunction in cancer etiology. Mutat Res (2011) 1.37
Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. Br J Haematol (2007) 1.37
Frequency and natural history of inherited bone marrow failure syndromes: the Israeli Inherited Bone Marrow Failure Registry. Haematologica (2010) 1.36
Leukocyte telomere length in a population-based case-control study of ovarian cancer: a pilot study. Cancer Causes Control (2009) 1.32
Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility. Lung Cancer (2009) 1.31
The Severe Chronic Neutropenia International Registry: 10-Year Follow-up Report. Support Cancer Ther (2006) 1.30
Association of longer telomeres with better health in centenarians. J Gerontol A Biol Sci Med Sci (2008) 1.28
Variants in the VCAM1 gene and risk for symptomatic stroke in sickle cell disease. Blood (2002) 1.27
How high are carrier frequencies of rare recessive syndromes? Contemporary estimates for Fanconi Anemia in the United States and Israel. Am J Med Genet A (2011) 1.23
A prospective analysis of telomere length and pancreatic cancer in the alpha-tocopherol beta-carotene cancer (ATBC) prevention study. Int J Cancer (2013) 1.22
A role for heterochromatin protein 1γ at human telomeres. Genes Dev (2011) 1.22
Dyskeratosis congenita: the first NIH clinical research workshop. Pediatr Blood Cancer (2009) 1.22
Updates on the biology and management of dyskeratosis congenita and related telomere biology disorders. Expert Rev Hematol (2013) 1.20
Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol (2010) 1.17
Polymorphisms in cytokine and cellular adhesion molecule genes and susceptibility to hematotoxicity among workers exposed to benzene. Cancer Res (2005) 1.16
Genome-wide association study of relative telomere length. PLoS One (2011) 1.16
Telomere length, telomere-related genes, and breast cancer risk: the breast cancer health disparities study. Genes Chromosomes Cancer (2013) 1.16
Intensive immunosuppression therapy for aplastic anemia associated with dyskeratosis congenita. Int J Hematol (2006) 1.13
Lung transplantation for pulmonary fibrosis in dyskeratosis congenita: Case Report and systematic literature review. BMC Blood Disord (2011) 1.12
LINE-1 methylation is inherited in familial testicular cancer kindreds. BMC Med Genet (2010) 1.11
Individualized risks of first adverse events in patients with Fanconi anemia. Blood (2004) 1.09
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood Cells Mol Dis (2006) 1.09
Squamous cell carcinomas in patients with Fanconi anemia and dyskeratosis congenita: a search for human papillomavirus. Int J Cancer (2013) 1.08
Current diagnosis of inherited bone marrow failure syndromes. Pediatr Hematol Oncol (2007) 1.08
Educational attainment and late life telomere length in the Health, Aging and Body Composition Study. Brain Behav Immun (2012) 1.08
Outcomes of allogeneic hematopoietic cell transplantation in patients with dyskeratosis congenita. Biol Blood Marrow Transplant (2013) 1.07
Telomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. PLoS One (2013) 1.07
Height at diagnosis and birth-weight as risk factors for osteosarcoma. Cancer Causes Control (2011) 1.07
Genomic characterization of the inherited bone marrow failure syndromes. Semin Hematol (2013) 1.07
A recessive founder mutation in regulator of telomere elongation helicase 1, RTEL1, underlies severe immunodeficiency and features of Hoyeraal Hreidarsson syndrome. PLoS Genet (2013) 1.05
Telomere biology in hematopoiesis and stem cell transplantation. Blood Rev (2011) 1.05
Sources of uncertainty and their association with medical decision making: exploring mechanisms in Fanconi anemia. Ann Behav Med (2013) 1.05